aspirin has been researched along with Osteolysis in 8 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Osteolysis: Dissolution of bone that particularly involves the removal or loss of calcium.
| Excerpt | Relevance | Reference |
|---|---|---|
| "23 (60%) of 38 human breast carcinomas had significant in-vitro osteolytic activity." | 5.26 | Breast-cancer osteolysis, bone metastases, and anti-osteolytic effect of aspirin. ( Dowsett, M; Easty, DM; Easty, GC; Neville, AM; Powles, TJ, 1976) |
| "Osteolysis effected in vitro by breast carcinomas can be inhibited by aspirin." | 3.65 | Human breast tumour-induced osteolysis and prostaglandins. ( Dowsett, M; Easty, DM; Easty, GC; Neville, AM; Powles, TJ, 1976) |
| "Aspirin was injected intraperitoneally twice daily for 11 days." | 1.51 | Aspirin alleviates orthopedic implant‑associated infection. ( Jiang, Y; Lin, JC; Qin, HJ; Ren, ML; Wang, SN; Wu, HT; Yu, B, 2019) |
| "23 (60%) of 38 human breast carcinomas had significant in-vitro osteolytic activity." | 1.26 | Breast-cancer osteolysis, bone metastases, and anti-osteolytic effect of aspirin. ( Dowsett, M; Easty, DM; Easty, GC; Neville, AM; Powles, TJ, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, Y | 1 |
| Wang, SN | 1 |
| Wu, HT | 1 |
| Qin, HJ | 1 |
| Ren, ML | 1 |
| Lin, JC | 1 |
| Yu, B | 1 |
| Wei, Y | 1 |
| Liu, Z | 1 |
| Zhu, X | 1 |
| Jiang, L | 1 |
| Shi, W | 1 |
| Wang, Y | 1 |
| Xu, N | 1 |
| Gang, F | 1 |
| Wang, X | 1 |
| Zhao, L | 1 |
| Lin, J | 1 |
| Sun, X | 1 |
| Loscocco, GG | 1 |
| Antonioli, E | 1 |
| Romano, I | 1 |
| Vergoni, F | 1 |
| Rotunno, G | 1 |
| Mannelli, F | 1 |
| Guglielmelli, P | 1 |
| Vannucchi, AM | 1 |
| Farah, AE | 1 |
| Rosenberg, F | 1 |
| Powles, TJ | 3 |
| Dowsett, M | 3 |
| Easty, GC | 3 |
| Easty, DM | 3 |
| Neville, AM | 4 |
| Coombes, RC | 1 |
| Gazet, JC | 2 |
| Ford, HT | 1 |
| Nash, AG | 1 |
| Baker, JW | 1 |
| Powles, JT | 1 |
1 review available for aspirin and Osteolysis
| Article | Year |
|---|---|
Potential therapeutic applications of aspirin and other cyclo-oxygenase inhibitors.
Topics: Animals; Aspirin; Blood Platelets; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Digestive Sys | 1980 |
7 other studies available for aspirin and Osteolysis
| Article | Year |
|---|---|
Aspirin alleviates orthopedic implant‑associated infection.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Female; Humans; I | 2019 |
Dual directions to address the problem of aseptic loosening via electrospun PLGA @ aspirin nanofiber coatings on titanium.
Topics: Aspirin; Humans; Nanofibers; Osteogenesis; Osteolysis; Titanium | 2020 |
Lenalidomide: A double-edged sword for concomitant multiple myeloma and post-essential thrombocythemia myelofibrosis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Bone Marrow; Calreticulin; Dexamethas | 2021 |
Breast-cancer osteolysis, bone metastases, and anti-osteolytic effect of aspirin.
Topics: Animals; Aspirin; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Cultur | 1976 |
Agents affecting osteolysis in patients with breast cancer.
Topics: Anti-Inflammatory Agents; Aspirin; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcitonin; Fe | 1979 |
In vitro osteolysis by human breast tumours.
Topics: Aspirin; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Female; Humans; In Vitro Techni | 1977 |
Human breast tumour-induced osteolysis and prostaglandins.
Topics: Aspirin; Bone Resorption; Breast Neoplasms; Female; Humans; Indomethacin; Osteolysis; Prostaglandins | 1976 |