Page last updated: 2024-10-23

aspirin and Osteogenic Sarcoma

aspirin has been researched along with Osteogenic Sarcoma in 12 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Herein, we describe the use of low-dose aspirin with high-dose MTX in a patient with osteosarcoma."8.98Concomitant Administration of High-dose Methotrexate and Low-dose Aspirin Without Any Delay in Methotrexate Clearance in a Patient With Osteosarcoma: A Case Report and Review of the Literature. ( Gupta, A; Hopyan, S; Koo, A; Renzi, S; Taylor, T; Tsimerman, E, 2018)
"MTT assay, colony formation assay, and apoptosis assay were employed to analyze the effects of aspirin on the osteosarcoma cell viability in vitro."7.81Aspirin Suppresses the Growth and Metastasis of Osteosarcoma through the NF-κB Pathway. ( Duan, T; Hu, K; Kang, T; Liao, D; Lv, X; Wang, G; Wang, X; Zhang, RH; Zhong, L, 2015)
"Vanadium is a trace element widely distributed in the environment."5.35Vanadium(IV) complexes inhibit adhesion, migration and colony formation of UMR106 osteosarcoma cells. ( Cortizo, AM; Etcheverry, SB; Molinuevo, MS, 2008)
" VOAspi-PbetaPL film inhibited cell proliferation in a dose-response manner and induced formation of approximately half of the thiobarbituric acid reactive substances (TBARS), an index of lipid peroxidation."5.31A vanadium/aspirin complex controlled release using a poly(beta-propiolactone) film. Effects on osteosarcoma cells. ( Alessandrini, JL; Cortizo, AM; Cortizo, MS; Etcheverr, SB, 2001)
"Herein, we describe the use of low-dose aspirin with high-dose MTX in a patient with osteosarcoma."4.98Concomitant Administration of High-dose Methotrexate and Low-dose Aspirin Without Any Delay in Methotrexate Clearance in a Patient With Osteosarcoma: A Case Report and Review of the Literature. ( Gupta, A; Hopyan, S; Koo, A; Renzi, S; Taylor, T; Tsimerman, E, 2018)
"MTT assay, colony formation assay, and apoptosis assay were employed to analyze the effects of aspirin on the osteosarcoma cell viability in vitro."3.81Aspirin Suppresses the Growth and Metastasis of Osteosarcoma through the NF-κB Pathway. ( Duan, T; Hu, K; Kang, T; Liao, D; Lv, X; Wang, G; Wang, X; Zhang, RH; Zhong, L, 2015)
"Vanadium is a trace element widely distributed in the environment."1.35Vanadium(IV) complexes inhibit adhesion, migration and colony formation of UMR106 osteosarcoma cells. ( Cortizo, AM; Etcheverry, SB; Molinuevo, MS, 2008)
" VOAspi-PbetaPL film inhibited cell proliferation in a dose-response manner and induced formation of approximately half of the thiobarbituric acid reactive substances (TBARS), an index of lipid peroxidation."1.31A vanadium/aspirin complex controlled release using a poly(beta-propiolactone) film. Effects on osteosarcoma cells. ( Alessandrini, JL; Cortizo, AM; Cortizo, MS; Etcheverr, SB, 2001)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Renzi, S1
Tsimerman, E1
Taylor, T1
Hopyan, S1
Koo, A1
Gupta, A1
Aisa, MC1
Datti, A1
Orlacchio, A1
Di Renzo, GC1
De Luna-Bertos, E2
Ramos-Torrecillas, J2
García-Martínez, O2
Guildford, A1
Santin, M1
Ruiz, C2
Liao, D1
Zhong, L1
Duan, T1
Zhang, RH1
Wang, X1
Wang, G1
Hu, K1
Lv, X1
Kang, T1
Díaz-Rodríguez, L1
DE DEUXCHAISNES, CN1
KRANE, SM1
Molinuevo, MS1
Cortizo, AM2
Etcheverry, SB1
Clezardin, P1
Drouin, J1
Morel-Kopp, MC1
Hanss, M1
Kehrel, B1
Serre, CM1
Kaplan, C1
Delmas, PD1
Cortizo, MS1
Alessandrini, JL1
Etcheverr, SB1
Donaldson, WF1
Hindman, BJ1
Koka, BV1
Byers, PD1

Reviews

2 reviews available for aspirin and Osteogenic Sarcoma

ArticleYear
Concomitant Administration of High-dose Methotrexate and Low-dose Aspirin Without Any Delay in Methotrexate Clearance in a Patient With Osteosarcoma: A Case Report and Review of the Literature.
    Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:6

    Topics: Aspirin; Bone Neoplasms; Child; Glomerular Filtration Rate; Humans; Male; Methotrexate; Osteosarcoma

2018
PAGET'S DISEASE OF BONE: CLINICAL AND METABOLIC OBSERVATIONS.
    Medicine, 1964, Volume: 43

    Topics: Alkaline Phosphatase; Aspirin; Blood; Bone and Bones; Calcium; Citrates; Fluorides; Geriatrics; Hear

1964

Other Studies

10 other studies available for aspirin and Osteogenic Sarcoma

ArticleYear
COX inhibitors and bone: A safer impact on osteoblasts by NO-releasing NSAIDs.
    Life sciences, 2018, Sep-01, Volume: 208

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Neoplasms; Cathepsin B; Cell Differentiation;

2018
Therapeutic doses of nonsteroidal anti-inflammatory drugs inhibit osteosarcoma MG-63 osteoblast-like cells maturation, viability, and biomineralization potential.
    TheScientificWorldJournal, 2013, Volume: 2013

    Topics: Alkaline Phosphatase; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Differentiation; Aspirin; B

2013
Aspirin Suppresses the Growth and Metastasis of Osteosarcoma through the NF-κB Pathway.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Dec-01, Volume: 21, Issue:23

    Topics: Animals; Apoptosis; Aspirin; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Ce

2015
Effect of aspirin on cell growth of human MG-63 osteosarcoma line.
    TheScientificWorldJournal, 2012, Volume: 2012

    Topics: Apoptosis; Aspirin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Humans; Male; Osteosar

2012
Vanadium(IV) complexes inhibit adhesion, migration and colony formation of UMR106 osteosarcoma cells.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:5

    Topics: Animals; Aspirin; Cell Adhesion; Cell Line, Tumor; Cell Movement; Colony-Forming Units Assay; Cyclic

2008
Role of platelet membrane glycoproteins Ib/IX and IIb/IIIa, and of platelet alpha-granule proteins in platelet aggregation induced by human osteosarcoma cells.
    Cancer research, 1993, Oct-01, Volume: 53, Issue:19

    Topics: Antibodies, Monoclonal; Aspirin; Bernard-Soulier Syndrome; Blood Platelets; Cell Communication; Huma

1993
A vanadium/aspirin complex controlled release using a poly(beta-propiolactone) film. Effects on osteosarcoma cells.
    Journal of biomaterials science. Polymer edition, 2001, Volume: 12, Issue:9

    Topics: Animals; Aspirin; Bone Neoplasms; Cell Division; Drug Combinations; Drug Delivery Systems; Kinetics;

2001
Orthopedic surgery.
    Surgery, gynecology & obstetrics, 1975, Volume: 140, Issue:2

    Topics: Animals; Aspirin; Bone Cysts; Dogs; Education, Medical; Hormones; Humans; Joint Prosthesis; Methods;

1975
Usefulness of the post-aspirin bleeding time.
    Anesthesiology, 1986, Volume: 64, Issue:3

    Topics: Adolescent; Aspirin; Bleeding Time; Blood Platelets; Hemorrhage; Hemostasis; Humans; Intraoperative

1986
Solitary benign osteoblastic lesions of bone. Osteoid osteoma and benign osteoblastoma.
    Cancer, 1968, Volume: 22, Issue:1

    Topics: Adult; Age Factors; Aspirin; Axons; Bone and Bones; Bone Neoplasms; Diagnosis, Differential; Female;

1968