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aspirin and Orphan Diseases

aspirin has been researched along with Orphan Diseases in 18 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Orphan Diseases: Rare diseases that have not been well studied.

Research Excerpts

ExcerptRelevanceReference
" We present the case of a 50-year-old male with the Samter-Beer triad of asthma, nasal polyps, and salicylate intolerance with an ST elevation myocardial infarction complicated with cardiac arrest due to multi-vessel coronary artery spasm secondary to aspirin anaphylaxis."3.81Kounis syndrome with Samter-Beer triad treated with intracoronary adrenaline. ( Ihdayhid, AR; Rankin, J, 2015)
" The strict adherence to aspirin and dipyridamole has led to no stroke or progression of the vasculopathy for 8 years."3.73Moyamoya syndrome in a splenectomized patient with beta-thalassemia intermedia. ( Hara, T; Kira, R; Ohga, S; Sanefuji, M; Torisu, H; Yoshiura, T, 2006)
" To the best of our knowledge, this is the third reported case of takotsubo cardiomyopathy following appropriately dosed intramuscular administration of epinephrine for anaphylaxis."1.43Rare case of stress cardiomyopathy due to intramuscular epinephrine administration. ( Lloyd, B; Lohani, S; Melnick, S; Nazir, S, 2016)
"At elderly age, Kawasaki disease may remain unrecognized with a subsequent delay in appropriate therapy and an increased risk of coronary artery aneurysms."1.39Rare refractory Kawasaki disease in an adolescent boy with cardiac and diffuse coronary artery involvement. ( Jankauskas, A; Jurkienė, N; Kėvalas, R; Kudzytė, J; Labanauskas, L; Rakauskienė, V; Šileikienė, R, 2013)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's13 (72.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yilmaz, OK1
Smithson, LE1
Vinay, K1
Sawatkar, G1
Dogra, S1
Saikia, UN1
Sun, Q1
Zhang, J1
Yang, Y1
Davda, N1
Osman, C1
Šileikienė, R1
Kudzytė, J1
Jankauskas, A1
Labanauskas, L1
Rakauskienė, V1
Jurkienė, N1
Kėvalas, R1
Yang, M1
Bai, X1
Xu, J1
Ni, J1
Tang, J1
Zeng, Y1
Fang, Q1
Ihdayhid, AR1
Rankin, J1
Man, BL1
Chi, MS1
Fu, YP1
Nazir, S1
Melnick, S1
Lohani, S1
Lloyd, B1
Inoue, S1
Okiyama, N1
Okune, M1
Shiraki, N1
Kessoku, R1
Fujimoto, M1
Penot, JP1
Pradeau, F1
Günther, C1
Meurer, M1
Stein, A1
Viehweg, A1
Lee-Kirsch, MA1
HOLT, KE1
Fisher, R1
Fisher, EA1
Peters, MR1
Hajsadeghi, S1
Jafarian Kerman, SR1
Pouraliakbar, H1
Mohammadi, R1
Metules, T1
Bauer, J1
Sanefuji, M1
Ohga, S1
Kira, R1
Yoshiura, T1
Torisu, H1
Hara, T1
Pyun, HW1
Lee, DH1
Kwon, SU1
Lee, JH1
Choi, CG1
Kim, SJ1
Suh, DC1

Reviews

2 reviews available for aspirin and Orphan Diseases

ArticleYear
Gallbladder Hydrops Associated With Kawasaki Disease: A Case Report and Literature Review.
    Clinical pediatrics, 2018, Volume: 57, Issue:3

    Topics: Aspirin; Child; Edema; Follow-Up Studies; Gallbladder Diseases; Humans; Immunoglobulins, Intravenous

2018
Clinical and histological characteristics of livedo racemosa in essential thrombocythemia: A report of two cases and review of the published works.
    The Journal of dermatology, 2017, Volume: 44, Issue:1

    Topics: Aged; Aspirin; Calreticulin; Humans; Hydroxyurea; Janus Kinase 2; Livedo Reticularis; Male; Middle A

2017

Other Studies

16 other studies available for aspirin and Orphan Diseases

ArticleYear
Klippel-Trénaunay syndrome: a case report of a rare vascular disorder identified in a rural Canadian hospital.
    Rural and remote health, 2019, Volume: 19, Issue:4

    Topics: Anticoagulants; Aspirin; Humans; Klippel-Trenaunay-Weber Syndrome; Male; Middle Aged; Newfoundland a

2019
Systemic lupus erythematosus with Degos disease: role of dermatoscopy in diagnosis.
    International journal of dermatology, 2017, Volume: 56, Issue:7

    Topics: Adolescent; Aspirin; Biopsy, Needle; Dermoscopy; Drug Therapy, Combination; Female; Humans; Hydroxyc

2017
Anterior spinal cord infarct: a rare yet disabling stroke.
    BMJ case reports, 2018, May-07, Volume: 2018

    Topics: Aged, 80 and over; Aspirin; Atorvastatin; Clopidogrel; Diagnosis, Differential; Humans; Hydroxymethy

2018
Rare refractory Kawasaki disease in an adolescent boy with cardiac and diffuse coronary artery involvement.
    Medicina (Kaunas, Lithuania), 2013, Volume: 49, Issue:7

    Topics: Adolescent; Anticoagulants; Aspirin; Coronary Aneurysm; Drug Resistance; Humans; Immunoglobulins, In

2013
Two young women with severe coronary arterial ostial narrowing: A potential subtype of Takayasu arteritis.
    International journal of cardiology, 2015, Volume: 189

    Topics: Adult; Aspirin; Clopidogrel; Coronary Angiography; Coronary Stenosis; Cyclophosphamide; Diagnosis, D

2015
Kounis syndrome with Samter-Beer triad treated with intracoronary adrenaline.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2015, Nov-15, Volume: 86, Issue:6

    Topics: Anaphylaxis; Aspirin; Asthma; Chest Pain; Coronary Stenosis; Coronary Vessels; Electrocardiography;

2015
Wall-eyed bilateral internuclear ophthalmoplaegia (WEBINO) from a paramedian mesencephalic infarct.
    BMJ case reports, 2015, Oct-13, Volume: 2015

    Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Stem Infarctions; Exotrop

2015
Rare case of stress cardiomyopathy due to intramuscular epinephrine administration.
    BMJ case reports, 2016, Jun-07, Volume: 2016

    Topics: Administration, Intranasal; Adrenergic beta-Antagonists; Adult; Anaphylaxis; Angiotensin-Converting

2016
[Iatrogenic dementia and extrapyramidal syndrome: rare adverse effect of valproic acid-aspirin combination].
    Presse medicale (Paris, France : 1983), 2010, Volume: 39, Issue:2

    Topics: Aged; Anticonvulsants; Aspirin; Basal Ganglia Diseases; Dementia; Drug Interactions; Drug Therapy, C

2010
Familial chilblain lupus--a monogenic form of cutaneous lupus erythematosus due to a heterozygous mutation in TREX1.
    Dermatology (Basel, Switzerland), 2009, Volume: 219, Issue:2

    Topics: Adolescent; Aspirin; Biopsy, Needle; Chronic Disease; Disease Progression; Drug Therapy, Combination

2009
The separation of acetylsalicylic acid, acetophenetidin, and caffeine.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1946, Volume: 35

    Topics: Aspirin; Caffeine; Phenacetin; Rare Diseases; Retinal Degeneration; Retinal Detachment; Salicylates

1946
A rare case of a coronary vascular ring arising from an anomalous single coronary artery.
    The Journal of invasive cardiology, 2012, Volume: 24, Issue:6

    Topics: Aged; Aspirin; Atorvastatin; Coronary Angiography; Coronary Vessel Anomalies; Drug Therapy, Combinat

2012
A huge coronary artery aneurysm in osteogenesis imperfecta: a case report.
    Acta medica Iranica, 2012, Volume: 50, Issue:11

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Aneurysm; Drug Therap

2012
Be on the lookout for this seasonal ailment.
    RN, 2006, Volume: 69, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child, Preschool; Coronary Aneurysm; Diagnosis, Di

2006
Moyamoya syndrome in a splenectomized patient with beta-thalassemia intermedia.
    Journal of child neurology, 2006, Volume: 21, Issue:1

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta-Thalassemia; Carotid Arteries; Di

2006
Internal carotid artery stenosis with ipsilateral persistent hypoglossal artery presenting as a multiterritorial embolic infarction: a case report.
    Acta radiologica (Stockholm, Sweden : 1987), 2007, Volume: 48, Issue:1

    Topics: Aged; Aspirin; Basilar Artery; Brain; Carotid Artery, Internal; Carotid Stenosis; Cerebral Infarctio

2007