aspirin has been researched along with Ornithine Carbamoyltransferase Deficiency Disease in 3 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Ornithine Carbamoyltransferase Deficiency Disease: An inherited urea cycle disorder associated with deficiency of the enzyme ORNITHINE CARBAMOYLTRANSFERASE, transmitted as an X-linked trait and featuring elevations of amino acids and ammonia in the serum. Clinical features, which are more prominent in males, include seizures, behavioral alterations, episodic vomiting, lethargy, and coma. (Menkes, Textbook of Child Neurology, 5th ed, pp49-50)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In Europe Reye's syndrome is a rather rare but often fatal disease affecting children and teenagers." | 1.27 | [Reye syndrome--a status review of current concepts of its pathogenesis]. ( Plauth, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Plauth, M | 1 |
| Yoshida, I | 1 |
| Yoshino, M | 1 |
| Watanabe, J | 1 |
| Yamashita, F | 1 |
| Thaler, MM | 1 |
1 review available for aspirin and Ornithine Carbamoyltransferase Deficiency Disease
| Article | Year |
|---|---|
Metabolic mechanisms in Reye syndrome. End of a Mystery?
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Aspirin; Brain Diseases; Carbamoyl-Phosphate Synthase | 1976 |
2 other studies available for aspirin and Ornithine Carbamoyltransferase Deficiency Disease
| Article | Year |
|---|---|
[Reye syndrome--a status review of current concepts of its pathogenesis].
Topics: Aflatoxins; Ammonia; Aspirin; Carbamoyl-Phosphate Synthase (Ammonia); Child; Fatty Acids, Nonesterif | 1984 |
Sudden onset of ornithine carbamoyltransferase deficiency after aspirin ingestion.
Topics: Adult; Aspirin; Coma; Humans; Male; Ornithine Carbamoyltransferase Deficiency Disease; Reye Syndrome | 1993 |