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aspirin and Optic Neuropathy, Ischemic

aspirin has been researched along with Optic Neuropathy, Ischemic in 22 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Optic Neuropathy, Ischemic: Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)

Research Excerpts

ExcerptRelevanceReference
"To examine the effect of aspirin use on the visual outcome of nonarteritic anterior ischemic optic neuropathy."7.69The effect of aspirin on the visual outcome of nonarteritic anterior ischemic optic neuropathy. ( Arnold, AC; Botelho, PJ; Johnson, LN, 1996)
"To determine the benefit of aspirin in reducing the risk of nonarteritic anterior ischemic optic neuropathy in the fellow eye following its occurrence in the first eye."7.69Aspirin therapy in nonarteritic anterior ischemic optic neuropathy. ( Beck, RW; Hayreh, SS; Moke, PS; Podhajsky, PA; Tan, ES, 1997)
"To examine the effect of aspirin use on the visual outcome of nonarteritic anterior ischemic optic neuropathy."3.69The effect of aspirin on the visual outcome of nonarteritic anterior ischemic optic neuropathy. ( Arnold, AC; Botelho, PJ; Johnson, LN, 1996)
"To determine the benefit of aspirin in reducing the risk of nonarteritic anterior ischemic optic neuropathy in the fellow eye following its occurrence in the first eye."3.69Aspirin therapy in nonarteritic anterior ischemic optic neuropathy. ( Beck, RW; Hayreh, SS; Moke, PS; Podhajsky, PA; Tan, ES, 1997)
"The objective of this study was to determine if aspirin reduces the incidence of second eye involvement after nonarteritic anterior ischemic optic neuropathy (NAION) in one eye."3.69Aspirin reduces the incidence of second eye NAION: a retrospective study. ( Frohman, L; Hirschfeld, J; Jacobs, J; Ku, C; Kupersmith, MJ; Sanderson, M; Warren, FA, 1997)
"Although giant cell or temporal arteritis represents 5-10% of ischaemic optic neuropathies and is the most common arteritis in people over 60 years old."2.46[Temporal arteritis: treatment controversies]. ( Balsalobre Aznar, J; Porta-Etessam, J, 2010)
"Takayasu arteritis is a granulomatous panarteritis that predominantly affects the aorta and its major branches."1.46Bilateral ocular ischemia-induced blindness as a presenting manifestation of Takayasu arteritis: a case report. ( Epafra, E; Janabi, M; Kazahura, P; Lyimo, F; Nicholaus, P; Pallangyo, P, 2017)
"Arteriosclerosis is the main cause of lacunar CVA and IOMP."1.33Clinical characteristics of patients with ischemic ocular nerve palsies and lacunar brain infarcts: a retrospective comparative study. ( Goldhammer, Y; Hartmann, B; Kessler, A; Pollak, L; Rabey, MJ, 2005)
"In 52 patients who presented with NAION between 1984 and 1997 adequate information was available regarding use of aspirin, presence of risk factors and second eye involvement."1.30Role of aspirin in reducing the frequency of second eye involvement in patients with non-arteritic anterior ischaemic optic neuropathy. ( Huna-Baron, R; Kurtz, S; Salomon, O; Seligsohn, U; Steinberg, DM, 1999)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (27.27)18.2507
2000's7 (31.82)29.6817
2010's7 (31.82)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Arnold, AC3
Egan, RA1
Lee, AG3
Van Stavern, GP3
Pallangyo, P1
Epafra, E1
Nicholaus, P1
Lyimo, F1
Kazahura, P1
Janabi, M1
Panos, GD1
Panos, LD1
Hafezi, F1
Gatzioufas, Z1
Assad, M1
Coffin-Pichonnet, S1
Billotte, C1
Denion, É1
Mears, KA1
Berger, CT1
Wolbers, M1
Meyer, P1
Daikeler, T1
Hess, C1
Balsalobre Aznar, J1
Porta-Etessam, J1
Hayreh, SS3
Pelegrín, L1
Mesquida, M1
Rey, A1
Sánchez-Dalmau, B1
Frohman, L2
Mercado, JL1
Purvin, VA1
Kawasaki, A1
WuDunn, D1
Goff, MJ1
Kerrison, JB1
Pollak, L1
Kessler, A1
Rabey, MJ1
Hartmann, B1
Goldhammer, Y1
Randhawa, S1
Botelho, PJ1
Johnson, LN1
Beck, RW2
Podhajsky, PA1
Tan, ES1
Moke, PS1
Kupersmith, MJ1
Sanderson, M1
Jacobs, J1
Hirschfeld, J1
Ku, C1
Warren, FA1
Salomon, O1
Huna-Baron, R1
Steinberg, DM1
Kurtz, S1
Seligsohn, U1
Malik, KP1
Kapoor, K1
Mehta, A1
Dadeya, S1
Guliani, BP1
Aggarwal, S1
Gupta, VS1

Reviews

4 reviews available for aspirin and Optic Neuropathy, Ischemic

ArticleYear
Aspirin Should Not Be Recommended to Prevent Second Eye Involvement in Patients With Nonarteritic Anterior Ischemic Optic Neuropathy.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2020, Volume: 40, Issue:2

    Topics: Aspirin; Humans; Optic Neuropathy, Ischemic; Platelet Aggregation Inhibitors; Visual Acuity

2020
Should Aspirin Be Prescribed to Prevent Recurrence in Nonarteritic Anterior Ischemic Optic Neuropathy?
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2020, Volume: 40, Issue:3

    Topics: Aspirin; Humans; Optic Neuropathy, Ischemic; Platelet Aggregation Inhibitors; Prescription Drugs; Re

2020
[Temporal arteritis: treatment controversies].
    Neurologia (Barcelona, Spain), 2010, Volume: 25, Issue:7

    Topics: Aspirin; Benzamides; Giant Cell Arteritis; Glucocorticoids; Humans; Imatinib Mesylate; Immunosuppres

2010
Vascular disorders in neuro-ophthalmology.
    Current opinion in neurology, 2011, Volume: 24, Issue:1

    Topics: Adrenal Cortex Hormones; Anticoagulants; Aspirin; Humans; Ophthalmology; Optic Neuropathy, Ischemic;

2011

Other Studies

18 other studies available for aspirin and Optic Neuropathy, Ischemic

ArticleYear
Bilateral ocular ischemia-induced blindness as a presenting manifestation of Takayasu arteritis: a case report.
    Journal of medical case reports, 2017, Jun-10, Volume: 11, Issue:1

    Topics: Anti-Inflammatory Agents; Aspirin; Blindness; Computed Tomography Angiography; Dexamethasone; Female

2017
Ischemic optic neuropathy after a long airplane flight: coincidence or rare economy class syndrome manifestation?
    Klinische Monatsblatter fur Augenheilkunde, 2014, Volume: 231, Issue:4

    Topics: Aircraft; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diagnosis, Differential; Humans; Male; M

2014
[Acute unilateral arteritic anterior ischemic optic neuropathy becoming bilateral despite corticosteroid therapy].
    Journal francais d'ophtalmologie, 2016, Volume: 39, Issue:1

    Topics: Acute Disease; Aged; Alzheimer Disease; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Disease P

2016
Bilateral simultaneous anterior ischaemic optic neuropathy associated with Sticky Platelet Syndrome.
    The British journal of ophthalmology, 2009, Volume: 93, Issue:7

    Topics: Adult; Aspirin; Blood Platelet Disorders; Fluorescein Angiography; Humans; Male; Optic Neuropathy, I

2009
High incidence of severe ischaemic complications in patients with giant cell arteritis irrespective of platelet count and size, and platelet inhibition.
    Rheumatology (Oxford, England), 2009, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Brain Ischemia; Cell Size; Female; Giant Cell Art

2009
Blind runner.
    Survey of ophthalmology, 2012, Volume: 57, Issue:5

    Topics: Adult; Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Hum

2012
Bilateral sequential nonarteritic anterior ischemic optic neuropathy: a comparison of visual outcomes in fellow eyes using quantitative analysis of goldmann visual fields.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2012, Volume: 130, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aspirin; Carbonic Anhydrase Inhibitors;

2012
Bilateral simultaneous anterior ischemic optic neuropathy in a young, healthy man.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:11

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Brimonidine Tartra

2003
Clinical characteristics of patients with ischemic ocular nerve palsies and lacunar brain infarcts: a retrospective comparative study.
    Acta neurologica Scandinavica, 2005, Volume: 111, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Brain I

2005
Sticky platelet syndrome and anterior ischaemic optic neuropathy.
    Clinical & experimental ophthalmology, 2007, Volume: 35, Issue:8

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelet Disorders; Humans; Male

2007
Reversible loss of vision due to posterior ischemic optic neuropathy.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1995, Volume: 30, Issue:6

    Topics: Acute Disease; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blindness

1995
The effect of aspirin on the visual outcome of nonarteritic anterior ischemic optic neuropathy.
    American journal of ophthalmology, 1996, Volume: 121, Issue:4

    Topics: Aged; Aspirin; Case-Control Studies; Female; Humans; Male; Middle Aged; Optic Neuropathy, Ischemic;

1996
Bilateral nonarteritic anterior ischemic optic neuropathy.
    Ophthalmology, 1997, Volume: 104, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Giant Cell Arteritis; Humans; Optic Neuropathy, Is

1997
Aspirin therapy in nonarteritic anterior ischemic optic neuropathy.
    American journal of ophthalmology, 1997, Volume: 123, Issue:2

    Topics: Aspirin; Cohort Studies; Humans; Optic Neuropathy, Ischemic; Platelet Aggregation Inhibitors; Retros

1997
Aspirin reduces the incidence of second eye NAION: a retrospective study.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 1997, Volume: 17, Issue:4

    Topics: Aged; Aspirin; Female; Functional Laterality; Humans; Incidence; Male; Middle Aged; Optic Neuropathy

1997
Role of aspirin in reducing the frequency of second eye involvement in patients with non-arteritic anterior ischaemic optic neuropathy.
    Eye (London, England), 1999, Volume: 13 ( Pt 3a)

    Topics: Adult; Age Factors; Aged; Aspirin; Dose-Response Relationship, Drug; Fibrinolytic Agents; Follow-Up

1999
Role of aspirin in reducing the frequency of second eye involvement in patients with non-arteritic anterior ischaemic optic neuropathy.
    Eye (London, England), 2000, Volume: 14 ( Pt 1)

    Topics: Aspirin; Fibrinolytic Agents; Humans; Optic Neuropathy, Ischemic; Platelet Aggregation Inhibitors

2000
Bilateral anterior ischaemic optic neuropathy in Takayasu arteritis.
    Indian journal of ophthalmology, 2002, Volume: 50, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Fluorescein Angiography; Glucocorticoids; H

2002