Page last updated: 2024-10-23

aspirin and Odontalgia

aspirin has been researched along with Odontalgia in 25 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"The effects of aspirin or 5-hydroxytryptamine (5-HT)-related drugs on the dental pain induced by electrical stimulation of tooth pulp afferent fibers were assessed in conscious monkeys."7.67Possible role of central serotoninergic neurons in the development of dental pain and aspirin-induced analgesia in the monkey. ( Lin, MT; Shyu, KW; Wu, TC, 1984)
"The effectiveness of nonprescription analgesics--acetaminophen and aspirin--in providing subjective relief of preoperative dental pain was evaluated in a varied population of adults."7.66Evaluation of acetaminophen and aspirin in the relief of preoperative dental pain. ( Kilkuts, A; Korberly, BH; Orkand, RK; Schreiber, GF; Segal, H, 1980)
"Piroxicam, a NSAID with a proved analgesic and antiphlogistic efficacy, largely used in rheumatic-orthopedic pathologies, has an antalgic action also in extra-rheumatic pathologies, such as postoperative and dental pain and primary dysmenorrhea."6.16[Piroxicam in analgesia]. ( della Pepa, C; Eandi, M; Rubinetto, MP, 1991)
"The effects of aspirin or 5-hydroxytryptamine (5-HT)-related drugs on the dental pain induced by electrical stimulation of tooth pulp afferent fibers were assessed in conscious monkeys."3.67Possible role of central serotoninergic neurons in the development of dental pain and aspirin-induced analgesia in the monkey. ( Lin, MT; Shyu, KW; Wu, TC, 1984)
"The effectiveness of nonprescription analgesics--acetaminophen and aspirin--in providing subjective relief of preoperative dental pain was evaluated in a varied population of adults."3.66Evaluation of acetaminophen and aspirin in the relief of preoperative dental pain. ( Kilkuts, A; Korberly, BH; Orkand, RK; Schreiber, GF; Segal, H, 1980)
"001, respectively) and 60 min after dosing (p < 0."2.41The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/ caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis). ( Kiersch, TA; Minić, MR, 2002)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199016 (64.00)18.7374
1990's4 (16.00)18.2507
2000's3 (12.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Voelker, M2
Schachtel, BP1
Cooper, SA2
Gatoulis, SC1
Dodd, MD2
Graham, CA1
TRANCHARD, M1
CHAMU, J1
MASURE, A1
SAVINEL, E1
DEHAENE, P1
LEBEURRE, P1
DESSINGES, S1
Shyu, KW1
Lin, MT1
Wu, TC1
Seymour, RA1
Korberly, BH1
Schreiber, GF1
Kilkuts, A1
Orkand, RK1
Segal, H1
Preshaw, PM1
Meechan, JG1
Schweiger, A1
Mason, C1
Porter, SR1
Madland, G1
Parry, J1
Vergne, P1
Bertin, P1
Trèves, R1
Kiersch, TA1
Minić, MR1
Bloomquist, DS1
Haegerstam, G1
Edwall, L1
Eandi, M1
della Pepa, C1
Rubinetto, MP1
Holmes, A1
Davidson, LE1
di Garzegna, AD1
Cassarino, G2
Ferretti, C1
Rainero, I1
Re, G1
Veglia, M1
Portaleone, P2
Hargreaves, KM1
Troullos, ES1
Dionne, RA1
Giacone, E1
Lee, MH1
Zarestsky, HH1
Ernst, M1
Dworkin, B1
Jonas, R1
Schubert, J1
Petersen, JK1
Riethe, P1
Wilske, E1
Yamamoto, I1
Inoki, R1
Shigenaga, Y1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Onset of Action of a Fast Release Aspirin Tablet and Acetaminophen Caplet in Sore Throat Pain[NCT01453400]Phase 3177 participants (Actual)Interventional2011-09-27Completed
Comparative Onset of Action of a Fast Release Aspirin Tablet in a Dental Impaction Pain Model[NCT01420094]Phase 3510 participants (Actual)Interventional2011-06-16Completed
Assessment of Preemptive Analgesic Effect of Caldolor® vs. Ofirmev® on Third Molar Surgery: A Prospective, Randomized, Double-blinded Clinical Trial[NCT02133326]Phase 267 participants (Actual)Interventional2014-03-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for aspirin and Odontalgia

ArticleYear
[Aspirin, pain and inflammation].
    La Revue de medecine interne, 2000, Volume: 21 Suppl 1

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Child; Colic; Controlle

2000
The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/ caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis).
    Current medical research and opinion, 2002, Volume: 18, Issue:1

    Topics: Adult; Antipyrine; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Ibupro

2002
[Piroxicam in analgesia].
    La Clinica terapeutica, 1991, Jan-31, Volume: 136, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Tolerance; Dysmenorrhea; Female; Humans; Pain

1991
Pharmacologic rationale for the treatment of acute pain.
    Dental clinics of North America, 1987, Volume: 31, Issue:4

    Topics: Acute Disease; Analgesics; Aspirin; Facial Pain; Humans; Nociceptors; Toothache

1987
[Analgesics, with special reference to recent trends].
    Nihon Shika Ishikai zasshi, 1968, Oct-11, Volume: 21, Issue:8

    Topics: Analgesics; Animals; Aspirin; Brain Stem; Central Nervous System; Dental Pulp; Depression, Chemical;

1968

Trials

6 trials available for aspirin and Odontalgia

ArticleYear
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Evaluation of onset of pain relief from micronized aspirin in a dental pain model.
    Inflammopharmacology, 2012, Volume: 20, Issue:4

    Topics: Adult; Aspirin; Chemistry, Pharmaceutical; Double-Blind Method; Female; Humans; Male; Tablets; Tooth

2012
[Piroxicam in analgesia].
    La Clinica terapeutica, 1991, Jan-31, Volume: 136, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Tolerance; Dysmenorrhea; Female; Humans; Pain

1991
[Clinical evaluation of the efficacy of suprofen as an analgesic compared to acetylsalicylic acid in toothache].
    Minerva stomatologica, 1986, Volume: 35, Issue:6

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Phenylpropi

1986
The analgesic effects of aspirin and placebo on experimentally induced tooth pulp pain.
    Journal of medicine, 1985, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Analgesia; Aspirin; Clinical Trials as Topic; Dental Pulp Diseases; Female; Human

1985
[Analgetic effects on the stimulus threshold of the human tooth].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:4

    Topics: Administration, Oral; Amides; Analgesics; Analysis of Variance; Aspirin; Caffeine; Clinical Trials a

1974

Other Studies

15 other studies available for aspirin and Odontalgia

ArticleYear
Unintentional overdose of analgesia secondary to acute dental pain.
    British dental journal, 2002, Aug-24, Volume: 193, Issue:4

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents,

2002
[THE USE OF SALICYLIC ACID DERIVATIVES IN PEDIATRICS].
    Gazette medicale de France, 1964, Jun-10, Volume: 71

    Topics: Analgesia; Aspirin; Bicarbonates; Biomedical Research; Child; Headache; Infant; Joint Diseases; Pedi

1964
[TRIALS WITH TH-2152 (CATALGINE). (APROPOS OF 397 CASES)].
    Gazette medicale de France, 1964, Jun-10, Volume: 71

    Topics: Arthritis; Aspirin; Bicarbonates; Biomedical Research; Headache; Humans; Influenza, Human; Joint Dis

1964
Possible role of central serotoninergic neurons in the development of dental pain and aspirin-induced analgesia in the monkey.
    Experimental neurology, 1984, Volume: 84, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Aspirin; Cyproheptadine; Dental Pulp; Fenclonine; Macaca; Male; Pa

1984
The efficacy of self-prescribed analgesics in the treatment of toothache.
    Journal of dentistry, 1983, Volume: 11, Issue:1

    Topics: Acetaminophen; Adult; Analgesics; Aspirin; Female; Humans; Male; Self Medication; Toothache

1983
Evaluation of acetaminophen and aspirin in the relief of preoperative dental pain.
    Journal of the American Dental Association (1939), 1980, Volume: 100, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Female; Humans; Male; Middle Aged; Mouth Diseases;

1980
Self-medication for the control of dental pain: what are our patients taking?
    Dental update, 1994, Volume: 21, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Aspirin; Chi-Square Distribution; Codeine; Consu

1994
[A fixed combination of acetylsalicylic acid and paracetamol is absolutely effective. Interview by Dr. rer. nat. Anita Schweiger].
    Fortschritte der Medizin, 1996, Feb-10, Volume: 114, Issue:4

    Topics: Analgesics; Aspirin; Barbiturates; Caffeine; Drug Combinations; Humans; Pain; Pain Measurement; Phen

1996
Early management of dental pain in children and adolescents.
    Journal of dentistry, 1997, Volume: 25, Issue:1

    Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal

1997
Pain control in endodontics.
    Dental clinics of North America, 1979, Volume: 23, Issue:4

    Topics: Acetaminophen; Analgesics; Aspirin; Cellulitis; Codeine; Dextropropoxyphene; Humans; Nausea; Pain; P

1979
Sodium acetylsalicylate and the role of prostaglandins in the mechanism of intradental pain.
    Acta odontologica Scandinavica, 1977, Volume: 35, Issue:2

    Topics: Administration, Topical; Animals; Arachidonic Acids; Aspirin; Cats; Cyclooxygenase Inhibitors; Evoke

1977
Reye's syndrome and analgesic choice in dentistry.
    British dental journal, 1989, Nov-25, Volume: 167, Issue:10

    Topics: Acetaminophen; Aspirin; Attitude; Child; Child, Preschool; Female; Health Education; Humans; Infant;

1989
[Correlation between dental pulp pain, blood levels of ACTH, cortisol and beta-endorphin and the analgesic efficacy of acetylsalicylic acid].
    Minerva stomatologica, 1987, Volume: 36, Issue:5

    Topics: Adrenocorticotropic Hormone; Adult; Aspirin; beta-Endorphin; Dental Caries; Dental Pulp Diseases; Dr

1987
[Local administration of acetylsalicylic acid in postoperative pain].
    Deutsche Stomatologie, 1972, Volume: 22, Issue:9

    Topics: Aspirin; Humans; Methods; Tooth Extraction; Toothache

1972
[Acetylsalicylic acid and the dentist].
    Tandlaegebladet, 1974, Volume: 78, Issue:5

    Topics: Aspirin; Humans; Toothache

1974