Page last updated: 2024-10-23

aspirin and Obesity, Morbid

aspirin has been researched along with Obesity, Morbid in 9 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Obesity, Morbid: The condition of weighing two, three, or more times the ideal weight, so called because it is associated with many serious and life-threatening disorders. In the BODY MASS INDEX, morbid obesity is defined as having a BMI greater than 40.0 kg/m2.

Research Excerpts

ExcerptRelevanceReference
"Aspirin use is associated with increased rates of marginal ulceration after RYGB."9.41Aspirin Use as a Risk Factor for Marginal Ulceration in Roux-en-Y Gastric Bypass Patients: A Meta-Analysis of 24,770 Patients. ( Clapp, B; Dayyeh, BA; Ghanem, OM; Hassan, O; Portela, RC; Sharma, I; Spaniolas, K; Vahibe, A, 2023)
"Aspirin use is associated with increased rates of marginal ulceration after RYGB."5.41Aspirin Use as a Risk Factor for Marginal Ulceration in Roux-en-Y Gastric Bypass Patients: A Meta-Analysis of 24,770 Patients. ( Clapp, B; Dayyeh, BA; Ghanem, OM; Hassan, O; Portela, RC; Sharma, I; Spaniolas, K; Vahibe, A, 2023)
" The patient was subsequently found to have incomplete inhibition of platelet activity despite being on clopidogrel 150 mg and aspirin 81 mg daily and having a normal CYP-2C19 genotype, suggesting that suboptimal antiplatelet inhibition, secondary to morbid obesity, contributed to his in-stent thrombosis."3.79Obesity and intracranial in-stent thrombosis. ( Koch, S; Reyes-Iglesias, Y; Rose, DZ; Yavagal, DR, 2013)
" Patients who received low-molecular-weight heparin for prophylaxis against deep venous thrombosis had a longer time until the postoperative wound was dry than did those treated with aspirin and mechanical foot compression or those who received Coumadin (warfarin); this difference was significant on the fifth postoperative day (p = 0."3.74Factors associated with prolonged wound drainage after primary total hip and knee arthroplasty. ( DeWal, H; Di Cesare, PE; Patel, VP; Preston, C; Sehgal, B; Walsh, M, 2007)
"For SA, Tmax significantly decreased after RYGB, while both Cmax and AUC0-24 significantly increased."2.82The Effect of Roux-en-Y Gastric Bypass Surgery in Morbidly Obese Patients on Pharmacokinetics of (Acetyl)Salicylic Acid and Omeprazole: the ERY-PAO Study. ( Mitrov-Winkelmolen, L; Overdiek, HWPM; Swank, DJ; Touw, DJ; van Buul-Gast, MW; van Schaik, RHN, 2016)
"Laparoscopic Roux-en-Y gastric bypass (LRYGB) surgery is a safe and effective procedure for patients with severe obesity."1.46Is Daily Low-Dose Aspirin Safe to Take Following Laparoscopic Roux-en-Y Gastric Bypass for Obesity Surgery? ( Amin, N; Anvari, M; Gmora, S; Hong, D; Kang, X; Tiboni, M, 2017)
"As the problem of morbid obesity has increased over the past several years in the United States, gastric bypass has become a viable option for many people seeking treatment."1.33Preventing vascular complications after gastric bypass. ( Heffline, MS, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Portela, RC1
Sharma, I1
Vahibe, A1
Hassan, O1
Spaniolas, K1
Dayyeh, BA1
Clapp, B1
Ghanem, OM1
Won, KB1
Shin, ES1
Kang, J1
Yang, HM1
Park, KW1
Han, KR1
Moon, KW1
Oh, SK1
Kim, U1
Rhee, MY1
Kim, DI1
Kim, SY1
Lee, SY1
Han, JK1
Koo, BK1
Kim, HS1
Mojkowska, A1
Gazdzinski, S1
Fraczek, M1
Wyleżoł, M1
Mitrov-Winkelmolen, L1
van Buul-Gast, MW1
Swank, DJ1
Overdiek, HWPM1
van Schaik, RHN1
Touw, DJ1
Kang, X1
Hong, D1
Anvari, M1
Tiboni, M1
Amin, N1
Gmora, S1
Linares Vicente, JA1
Pérez, JO1
Lacasa, RC1
Rose, DZ1
Koch, S1
Reyes-Iglesias, Y1
Yavagal, DR1
Heffline, MS1
Patel, VP1
Walsh, M1
Sehgal, B1
Preston, C1
DeWal, H1
Di Cesare, PE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Blood Saving Effect and Wound-related Complications of Tranexamic Acid in Mininally Invasive Total Knee Arthroplasty With Rivaroxaban as Thromboprophylaxis[NCT02458729]Phase 4294 participants (Actual)Interventional2012-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aspirin and Obesity, Morbid

ArticleYear
Aspirin Use as a Risk Factor for Marginal Ulceration in Roux-en-Y Gastric Bypass Patients: A Meta-Analysis of 24,770 Patients.
    The American surgeon, 2023, Volume: 89, Issue:6

    Topics: Aspirin; Gastric Bypass; Humans; Obesity, Morbid; Retrospective Studies; Risk Factors; Ulcer

2023

Trials

2 trials available for aspirin and Obesity, Morbid

ArticleYear
Body Mass Index and Major Adverse Events During Chronic Antiplatelet Monotherapy After Percutaneous Coronary Intervention With Drug-Eluting Stents - Results From the HOST-EXAM Trial.
    Circulation journal : official journal of the Japanese Circulation Society, 2023, 01-25, Volume: 87, Issue:2

    Topics: Aspirin; Body Mass Index; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Obesit

2023
The Effect of Roux-en-Y Gastric Bypass Surgery in Morbidly Obese Patients on Pharmacokinetics of (Acetyl)Salicylic Acid and Omeprazole: the ERY-PAO Study.
    Obesity surgery, 2016, Volume: 26, Issue:9

    Topics: Administration, Oral; Anti-Ulcer Agents; Area Under Curve; Aspirin; Female; Gastric Bypass; Humans;

2016

Other Studies

6 other studies available for aspirin and Obesity, Morbid

ArticleYear
Gastric Ulcer Hemorrhage - a Potential Life-Threatening Complication of Intragastric Balloon Treatment of Obesity.
    Obesity facts, 2017, Volume: 10, Issue:2

    Topics: Adult; Aspirin; Bariatric Surgery; Gastric Balloon; Gastrointestinal Hemorrhage; Helicobacter Infect

2017
Is Daily Low-Dose Aspirin Safe to Take Following Laparoscopic Roux-en-Y Gastric Bypass for Obesity Surgery?
    Obesity surgery, 2017, Volume: 27, Issue:5

    Topics: Adult; Aspirin; Female; Gastric Bypass; Humans; Laparoscopy; Male; Middle Aged; Obesity, Morbid; Pep

2017
Long-term successful percutaneous coronary intervention in factor VII deficiency.
    The Journal of invasive cardiology, 2012, Volume: 24, Issue:6

    Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Stenosis; Diabetes M

2012
Obesity and intracranial in-stent thrombosis.
    Journal of neurointerventional surgery, 2013, Sep-01, Volume: 5, Issue:5

    Topics: Abciximab; Angioplasty, Balloon; Antibodies, Monoclonal; Aspirin; Body Mass Index; Brain Ischemia; C

2013
Preventing vascular complications after gastric bypass.
    Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing, 2006, Volume: 24, Issue:2

    Topics: Adult; Aged; Anticoagulants; Aspirin; Bandages; Clinical Protocols; Drug Monitoring; Early Ambulatio

2006
Factors associated with prolonged wound drainage after primary total hip and knee arthroplasty.
    The Journal of bone and joint surgery. American volume, 2007, Volume: 89, Issue:1

    Topics: Aged; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Body Mass Index; Dra

2007