aspirin has been researched along with Nerve Degeneration in 9 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent randomized trials have shown that cilostazol is superior to aspirin for secondary stroke prevention." | 9.16 | Cilostazol combined with aspirin prevents early neurological deterioration in patients with acute ischemic stroke: a pilot study. ( Nakamura, T; Tsuruta, S; Uchiyama, S, 2012) |
| "This paper will examine how cerebral perfusion deficits in cocaine abusers may be a target for pharmacotherapy." | 8.80 | Pharmacotherapy of cerebral ischemia in cocaine dependence. ( Kosten, TR, 1998) |
| "The potential neuroprotective effects of the novel nitro-derivate of aspirin (NCX4016) on permanent focal cerebral ischemia in spontaneously hypertensive rats (SHRs) was investigated." | 7.71 | Nitro-aspirin (NCX4016) reduces brain damage induced by focal cerebral ischemia in the rat. ( Ambrosini, MV; Del Soldato, P; Fredduzzi, S; Mariucci, G; Tantucci, M, 2001) |
| "Recent randomized trials have shown that cilostazol is superior to aspirin for secondary stroke prevention." | 5.16 | Cilostazol combined with aspirin prevents early neurological deterioration in patients with acute ischemic stroke: a pilot study. ( Nakamura, T; Tsuruta, S; Uchiyama, S, 2012) |
| "This paper will examine how cerebral perfusion deficits in cocaine abusers may be a target for pharmacotherapy." | 4.80 | Pharmacotherapy of cerebral ischemia in cocaine dependence. ( Kosten, TR, 1998) |
| "The potential neuroprotective effects of the novel nitro-derivate of aspirin (NCX4016) on permanent focal cerebral ischemia in spontaneously hypertensive rats (SHRs) was investigated." | 3.71 | Nitro-aspirin (NCX4016) reduces brain damage induced by focal cerebral ischemia in the rat. ( Ambrosini, MV; Del Soldato, P; Fredduzzi, S; Mariucci, G; Tantucci, M, 2001) |
| "The effect of capsaicin-sensitive nerve degeneration (capsaicin-treatment) was investigated on the antral ulcer induction by the combined administration of 2-deoxy-D-glucose (2-DG; 200 mg/kg, i." | 3.68 | Aggravation by the capsaicin-treatment of gastric antral ulcer induced by the combination of 2-deoxy-D-glucose, aspirin and ammonia in rats. ( Uchida, M; Watanabe, K; Yano, S, 1991) |
| "Aspirin, which has been shown to block phosphorylation of the IkappaB component of the cytoplasmic NF-kappaB complex, significantly suppressed glutamate-induced cell death, whereas the NF-kappaB decoy oligonucleotide potentiated it." | 1.33 | Distinct nuclear factor-kappaB/Rel proteins have opposing modulatory effects in glutamate-induced cell death in HT22 cells. ( Arakawa, M; Ishige, K; Ito, Y; Saito, H; Tanaka, M, 2005) |
| "Aspirin treatment improved survival ratio and stroke index, and decreased ischemically injured cell numbers in cortex." | 1.31 | Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia. ( Hosomi, N; Kohno, M; Mizushige, K; Ohyama, H; Takahashi, T, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, T | 1 |
| Tsuruta, S | 1 |
| Uchiyama, S | 1 |
| Ishige, K | 1 |
| Tanaka, M | 1 |
| Arakawa, M | 1 |
| Saito, H | 1 |
| Ito, Y | 1 |
| Di Matteo, V | 1 |
| Pierucci, M | 1 |
| Di Giovanni, G | 1 |
| Di Santo, A | 1 |
| Poggi, A | 1 |
| Benigno, A | 1 |
| Esposito, E | 1 |
| Kosten, TR | 1 |
| Casper, D | 1 |
| Yaparpalvi, U | 1 |
| Rempel, N | 1 |
| Werner, P | 1 |
| Fredduzzi, S | 1 |
| Mariucci, G | 1 |
| Tantucci, M | 1 |
| Del Soldato, P | 1 |
| Ambrosini, MV | 1 |
| Ohyama, H | 1 |
| Hosomi, N | 1 |
| Takahashi, T | 1 |
| Mizushige, K | 1 |
| Kohno, M | 1 |
| De Cristóbal, J | 1 |
| Madrigal, JL | 1 |
| Lizasoain, I | 1 |
| Lorenzo, P | 1 |
| Leza, JC | 1 |
| Moro, MA | 1 |
| Uchida, M | 1 |
| Yano, S | 1 |
| Watanabe, K | 1 |
1 review available for aspirin and Nerve Degeneration
| Article | Year |
|---|---|
Pharmacotherapy of cerebral ischemia in cocaine dependence.
Topics: Aspirin; Brain; Brain Ischemia; Cerebrovascular Circulation; Cocaine; Cocaine-Related Disorders; Cog | 1998 |
1 trial available for aspirin and Nerve Degeneration
| Article | Year |
|---|---|
Cilostazol combined with aspirin prevents early neurological deterioration in patients with acute ischemic stroke: a pilot study.
Topics: Aged; Aspirin; Brain Ischemia; Cilostazol; Drug Therapy, Combination; Female; Humans; Male; Middle A | 2012 |
7 other studies available for aspirin and Nerve Degeneration
| Article | Year |
|---|---|
Distinct nuclear factor-kappaB/Rel proteins have opposing modulatory effects in glutamate-induced cell death in HT22 cells.
Topics: Amino Acid Transport System y+; Animals; Aspirin; Cell Death; Cell Line, Transformed; Cell Survival; | 2005 |
Aspirin protects striatal dopaminergic neurons from neurotoxin-induced degeneration: an in vivo microdialysis study.
Topics: Analysis of Variance; Animals; Aspirin; Chromatography, High Pressure Liquid; Corpus Striatum; Dopam | 2006 |
Ibuprofen protects dopaminergic neurons against glutamate toxicity in vitro.
Topics: Acetaminophen; Animals; Aspirin; Cell Count; Cells, Cultured; Dopamine; Fetus; Glutamic Acid; Ibupro | 2000 |
Nitro-aspirin (NCX4016) reduces brain damage induced by focal cerebral ischemia in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Astrocytes; Brain; Brain Injur | 2001 |
Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia.
Topics: Animals; Antithrombins; Arginine; Aspirin; Blood Pressure; Brain Edema; Cerebrovascular Circulation; | 2001 |
Aspirin inhibits stress-induced increase in plasma glutamate, brain oxidative damage and ATP fall in rats.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Cerebral C | 2002 |
Aggravation by the capsaicin-treatment of gastric antral ulcer induced by the combination of 2-deoxy-D-glucose, aspirin and ammonia in rats.
Topics: Ammonia; Animals; Aspirin; Capsaicin; Deoxyglucose; Gastric Acid; Gastric Mucosa; Male; Nerve Degene | 1991 |