aspirin has been researched along with Neonatal Death in 14 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Neonatal Death: The death of a live-born INFANT less than 28 days of age.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the impact of low-dose aspirin (LDA) starting in early pregnancy on delaying preterm hypertensive disorders of pregnancy." | 9.69 | Aspirin delays the onset of hypertensive disorders of pregnancy among nulliparous pregnant women: A secondary analysis of the ASPIRIN trial. ( Bauserman, M; Bucher, S; Carlo, WA; Chomba, E; Das, P; Derman, RJ; Esamai, F; Figueroa, L; Goco, N; Goldenberg, RL; Goudar, SS; Hibberd, PL; Hoffman, MK; Jessani, S; Kavi, A; Koso-Thomas, M; Krebs, NF; Lokangaka, A; McClure, EM; Metgud, MC; Moore, J; Mwenechanya, M; Nielsen, E; Patel, A; Saleem, S; Silver, R; Somannavar, MS; Tshefu, A, 2023) |
| "The Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas trial was a landmark study that demonstrated a reduction in preterm birth and hypertensive disorders of pregnancy in nulliparous women who received low-dose aspirin." | 9.69 | The impact of risk factors on aspirin's efficacy for the prevention of preterm birth. ( Achieng, E; Bauserman, M; Bucher, S; Carlo, WA; Chomba, E; Das, P; Derman, RJ; Esamai, F; Figueroa, L; Goco, N; Goldenberg, RL; Goudar, SS; Hemingway-Foday, J; Hibberd, PL; Hoffman, MK; Jessani, S; Kavi, A; Krebs, NF; Kurhe, K; Liechty, EA; Lokangaka, A; McClure, EM; Metgud, M; Moore, J; Nuss, EE; Nyongesa, P; Okitawutshu, J; Saleem, S; Silver, RM; Somannavar, M; Tembo, AM; Tshefu, A, 2023) |
| "Low dose aspirin (LDA) is an effective strategy to reduce preterm birth." | 9.51 | The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries. ( Bauserman, M; Bose, CL; Carlo, WA; Chomba, E; Derman, RJ; Esamai, F; Goldenberg, RL; Hemingway-Foday, J; Hoffman, M; Jessani, S; Koso-Thomas, M; Leuba, SI; Liechty, EA; Lokangaka, A; McClure, EM; Meshnick, SR; Moore, J; Nolen, TL; Patterson, J; Saleem, S; Tsehfu, A, 2022) |
| "Evidence has shown significant benefits of aspirin for preventing pre-eclampsia." | 9.41 | Prevention of pre-eclampsia with aspirin: A systematic review of guidelines and evaluation of the quality of recommendation evidence. ( Ali, R; McDonald, SD; Morfaw, F; Ninan, K, 2023) |
| "This systematic review and meta-analysis investigated whether the use of low-dose aspirin during pregnancy by women with chronic hypertension reduces the odds of superimposed preeclampsia and poor perinatal outcomes." | 9.41 | Low-dose aspirin for the prevention of superimposed preeclampsia in women with chronic hypertension: a systematic review and meta-analysis. ( Giorgione, V; Richards, EMF; Stevens, O; Thilaganathan, B, 2023) |
| "Diagnosis of preeclampsia; adverse pregnancy health outcomes and complications including eclampsia, perinatal mortality, preterm birth, small for gestational age, and potential bleeding harms or infant/child harms from aspirin exposure." | 9.12 | Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. ( Henderson, JT; Redmond, N; Senger, CA; Thomas, RG; Vesco, KK, 2021) |
| "The USPSTF concludes with moderate certainty that there is a substantial net benefit of daily low-dose aspirin use to reduce the risk for preeclampsia, preterm birth, small for gestational age/intrauterine growth restriction, and perinatal mortality in pregnant persons at high risk for preeclampsia." | 8.02 | Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: US Preventive Services Task Force Recommendation Statement. ( Barry, MJ; Cabana, M; Caughey, AB; Davidson, KW; Davis, EM; Donahue, KE; Doubeni, CA; Kubik, M; Li, L; Mangione, CM; Ogedegbe, G; Pbert, L; Silverstein, M; Simon, MA; Stevermer, J; Tseng, CW; Wong, JB, 2021) |
| "Premature birth is associated with an increased risk of mortality and morbidity, and strategies to prevent preterm birth are few in number and resource intensive." | 5.91 | Cost-effectiveness of low-dose aspirin for the prevention of preterm birth: a prospective study of the Global Network for Women's and Children's Health Research. ( Achieng, E; Bose, CL; Bresnahan, BW; Bucher, S; Carlo, WA; Chicuy, J; Chomba, E; Das, P; Derman, RJ; Esamai, F; Figueroa, L; Goco, N; Goldenberg, RL; Goudar, SS; Hibberd, PL; Hoffman, M; Jessani, S; Kavi, A; Koso-Thomas, M; Krebs, NF; Kurhe, K; Liechty, EA; Lokangaka, A; McClure, EM; Metgud, M; Moore, J; Mwapule, A; Mwenechanya, M; Neuwahl, S; Nyongesa, P; Okitawutshu, J; Patel, A; Patterson, JK; Saleem, S; Somannavar, M; Tshefu, A, 2023) |
| "To assess the impact of low-dose aspirin (LDA) starting in early pregnancy on delaying preterm hypertensive disorders of pregnancy." | 5.69 | Aspirin delays the onset of hypertensive disorders of pregnancy among nulliparous pregnant women: A secondary analysis of the ASPIRIN trial. ( Bauserman, M; Bucher, S; Carlo, WA; Chomba, E; Das, P; Derman, RJ; Esamai, F; Figueroa, L; Goco, N; Goldenberg, RL; Goudar, SS; Hibberd, PL; Hoffman, MK; Jessani, S; Kavi, A; Koso-Thomas, M; Krebs, NF; Lokangaka, A; McClure, EM; Metgud, MC; Moore, J; Mwenechanya, M; Nielsen, E; Patel, A; Saleem, S; Silver, R; Somannavar, MS; Tshefu, A, 2023) |
| "The Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas trial was a landmark study that demonstrated a reduction in preterm birth and hypertensive disorders of pregnancy in nulliparous women who received low-dose aspirin." | 5.69 | The impact of risk factors on aspirin's efficacy for the prevention of preterm birth. ( Achieng, E; Bauserman, M; Bucher, S; Carlo, WA; Chomba, E; Das, P; Derman, RJ; Esamai, F; Figueroa, L; Goco, N; Goldenberg, RL; Goudar, SS; Hemingway-Foday, J; Hibberd, PL; Hoffman, MK; Jessani, S; Kavi, A; Krebs, NF; Kurhe, K; Liechty, EA; Lokangaka, A; McClure, EM; Metgud, M; Moore, J; Nuss, EE; Nyongesa, P; Okitawutshu, J; Saleem, S; Silver, RM; Somannavar, M; Tembo, AM; Tshefu, A, 2023) |
| "Low dose aspirin (LDA) is an effective strategy to reduce preterm birth." | 5.51 | The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries. ( Bauserman, M; Bose, CL; Carlo, WA; Chomba, E; Derman, RJ; Esamai, F; Goldenberg, RL; Hemingway-Foday, J; Hoffman, M; Jessani, S; Koso-Thomas, M; Leuba, SI; Liechty, EA; Lokangaka, A; McClure, EM; Meshnick, SR; Moore, J; Nolen, TL; Patterson, J; Saleem, S; Tsehfu, A, 2022) |
| "Evidence has shown significant benefits of aspirin for preventing pre-eclampsia." | 5.41 | Prevention of pre-eclampsia with aspirin: A systematic review of guidelines and evaluation of the quality of recommendation evidence. ( Ali, R; McDonald, SD; Morfaw, F; Ninan, K, 2023) |
| "This systematic review and meta-analysis investigated whether the use of low-dose aspirin during pregnancy by women with chronic hypertension reduces the odds of superimposed preeclampsia and poor perinatal outcomes." | 5.41 | Low-dose aspirin for the prevention of superimposed preeclampsia in women with chronic hypertension: a systematic review and meta-analysis. ( Giorgione, V; Richards, EMF; Stevens, O; Thilaganathan, B, 2023) |
| "Diagnosis of preeclampsia; adverse pregnancy health outcomes and complications including eclampsia, perinatal mortality, preterm birth, small for gestational age, and potential bleeding harms or infant/child harms from aspirin exposure." | 5.12 | Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. ( Henderson, JT; Redmond, N; Senger, CA; Thomas, RG; Vesco, KK, 2021) |
| "To perform a meta-analysis and meta-regression of randomized controlled trials (RCTs) to evaluate the impact of low-dose aspirin (LDA) on perinatal outcome, independent of its effect on pre-eclampsia (PE), preterm birth and low birth weight." | 5.05 | Impact of low-dose aspirin on adverse perinatal outcome: meta-analysis and meta-regression. ( Hartel, G; Kumar, S; Robertson, NT; Turner, JM, 2020) |
| "The USPSTF concludes with moderate certainty that there is a substantial net benefit of daily low-dose aspirin use to reduce the risk for preeclampsia, preterm birth, small for gestational age/intrauterine growth restriction, and perinatal mortality in pregnant persons at high risk for preeclampsia." | 4.02 | Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: US Preventive Services Task Force Recommendation Statement. ( Barry, MJ; Cabana, M; Caughey, AB; Davidson, KW; Davis, EM; Donahue, KE; Doubeni, CA; Kubik, M; Li, L; Mangione, CM; Ogedegbe, G; Pbert, L; Silverstein, M; Simon, MA; Stevermer, J; Tseng, CW; Wong, JB, 2021) |
| "When superimposed preeclampsia was present, it developed at an earlier gestational age among the group without GDM (35 ± 5 vs." | 2.82 | Rate of Gestational Diabetes Mellitus and Pregnancy Outcomes in Patients with Chronic Hypertension. ( Blackwell, SC; Haidar, ZA; Leon, MG; Longo, M; Mendez-Figueroa, H; Moussa, HN; Pedroza, C; Sibai, BM, 2016) |
| "Women at an increased risk of preeclampsia should be offered antiplatelet therapy, regardless of whether they are first seen before or after 16 weeks' gestation." | 2.55 | Antiplatelet therapy before or after 16 weeks' gestation for preventing preeclampsia: an individual participant data meta-analysis. ( Askie, L; Duley, L; Hunter, K; Meher, S, 2017) |
| "Premature birth is associated with an increased risk of mortality and morbidity, and strategies to prevent preterm birth are few in number and resource intensive." | 1.91 | Cost-effectiveness of low-dose aspirin for the prevention of preterm birth: a prospective study of the Global Network for Women's and Children's Health Research. ( Achieng, E; Bose, CL; Bresnahan, BW; Bucher, S; Carlo, WA; Chicuy, J; Chomba, E; Das, P; Derman, RJ; Esamai, F; Figueroa, L; Goco, N; Goldenberg, RL; Goudar, SS; Hibberd, PL; Hoffman, M; Jessani, S; Kavi, A; Koso-Thomas, M; Krebs, NF; Kurhe, K; Liechty, EA; Lokangaka, A; McClure, EM; Metgud, M; Moore, J; Mwapule, A; Mwenechanya, M; Neuwahl, S; Nyongesa, P; Okitawutshu, J; Patel, A; Patterson, JK; Saleem, S; Somannavar, M; Tshefu, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 10 (71.43) | 2.80 |
| Authors | Studies |
|---|---|
| Davidson, KW | 1 |
| Barry, MJ | 1 |
| Mangione, CM | 1 |
| Cabana, M | 1 |
| Caughey, AB | 1 |
| Davis, EM | 1 |
| Donahue, KE | 1 |
| Doubeni, CA | 1 |
| Kubik, M | 1 |
| Li, L | 1 |
| Ogedegbe, G | 1 |
| Pbert, L | 1 |
| Silverstein, M | 1 |
| Simon, MA | 1 |
| Stevermer, J | 1 |
| Tseng, CW | 1 |
| Wong, JB | 1 |
| Henderson, JT | 1 |
| Vesco, KK | 1 |
| Senger, CA | 1 |
| Thomas, RG | 1 |
| Redmond, N | 1 |
| Bauserman, M | 3 |
| Leuba, SI | 1 |
| Hemingway-Foday, J | 2 |
| Nolen, TL | 1 |
| Moore, J | 4 |
| McClure, EM | 4 |
| Lokangaka, A | 4 |
| Tsehfu, A | 1 |
| Patterson, J | 1 |
| Liechty, EA | 3 |
| Esamai, F | 4 |
| Carlo, WA | 4 |
| Chomba, E | 4 |
| Goldenberg, RL | 4 |
| Saleem, S | 4 |
| Jessani, S | 4 |
| Koso-Thomas, M | 3 |
| Hoffman, M | 2 |
| Derman, RJ | 4 |
| Meshnick, SR | 1 |
| Bose, CL | 2 |
| Ninan, K | 1 |
| Ali, R | 1 |
| Morfaw, F | 1 |
| McDonald, SD | 1 |
| Richards, EMF | 1 |
| Giorgione, V | 1 |
| Stevens, O | 1 |
| Thilaganathan, B | 1 |
| Patterson, JK | 1 |
| Neuwahl, S | 1 |
| Goco, N | 3 |
| Goudar, SS | 3 |
| Metgud, M | 2 |
| Somannavar, M | 2 |
| Kavi, A | 3 |
| Okitawutshu, J | 2 |
| Tshefu, A | 3 |
| Mwapule, A | 1 |
| Mwenechanya, M | 2 |
| Chicuy, J | 1 |
| Figueroa, L | 3 |
| Krebs, NF | 3 |
| Kurhe, K | 2 |
| Das, P | 3 |
| Patel, A | 2 |
| Hibberd, PL | 3 |
| Achieng, E | 2 |
| Nyongesa, P | 2 |
| Bucher, S | 3 |
| Bresnahan, BW | 1 |
| Dimitriadis, E | 1 |
| Rolnik, DL | 1 |
| Zhou, W | 1 |
| Estrada-Gutierrez, G | 1 |
| Koga, K | 1 |
| Francisco, RPV | 1 |
| Whitehead, C | 1 |
| Hyett, J | 1 |
| da Silva Costa, F | 1 |
| Nicolaides, K | 1 |
| Menkhorst, E | 1 |
| Hoffman, MK | 2 |
| Somannavar, MS | 1 |
| Metgud, MC | 1 |
| Nielsen, E | 1 |
| Silver, R | 1 |
| Nuss, EE | 1 |
| Tembo, AM | 1 |
| Silver, RM | 1 |
| Turner, JM | 1 |
| Robertson, NT | 1 |
| Hartel, G | 1 |
| Kumar, S | 1 |
| Käehne, LV | 1 |
| Rørbye, C | 1 |
| Leon, MG | 1 |
| Moussa, HN | 1 |
| Longo, M | 1 |
| Pedroza, C | 1 |
| Haidar, ZA | 1 |
| Mendez-Figueroa, H | 1 |
| Blackwell, SC | 1 |
| Sibai, BM | 1 |
| von Dadelszen, P | 1 |
| Magee, LA | 1 |
| Meher, S | 1 |
| Duley, L | 1 |
| Hunter, K | 1 |
| Askie, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Best Practice Alert (BPA) for Low Dose Aspirin Recommendation in High-risk Pregnancies: a Randomized Controlled Trial[NCT05802940] | 640 participants (Anticipated) | Interventional | 2023-06-19 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for aspirin and Neonatal Death
| Article | Year |
|---|---|
Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Infant, Newborn; Infant, Small for | 2021 |
Prevention of pre-eclampsia with aspirin: A systematic review of guidelines and evaluation of the quality of recommendation evidence.
Topics: Aspirin; Female; Humans; Infant, Newborn; Perinatal Death; Pre-Eclampsia; Pregnancy | 2023 |
Low-dose aspirin for the prevention of superimposed preeclampsia in women with chronic hypertension: a systematic review and meta-analysis.
Topics: Aspirin; Female; Humans; Hypertension; Infant, Newborn; Perinatal Death; Pre-Eclampsia; Pregnancy; P | 2023 |
Pre-eclampsia.
Topics: Aspirin; Female; Humans; Hypertension; Infant, Newborn; Perinatal Death; Pre-Eclampsia; Pregnancy; P | 2023 |
Impact of low-dose aspirin on adverse perinatal outcome: meta-analysis and meta-regression.
Topics: Abruptio Placentae; Apgar Score; Aspirin; Delivery, Obstetric; Female; Fetal Growth Retardation; Hum | 2020 |
[Treatment with low-dose acetylsalicylic acid can reduce risk of pre-eclampsia in high-risk pregnant women].
Topics: Aspirin; Early Medical Intervention; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Peri | 2017 |
Preventing deaths due to the hypertensive disorders of pregnancy.
Topics: Aspirin; Birth Intervals; Calcium; Cardiotocography; Dietary Supplements; Eclampsia; Female; Food Su | 2016 |
Antiplatelet therapy before or after 16 weeks' gestation for preventing preeclampsia: an individual participant data meta-analysis.
Topics: Aspirin; Female; Humans; Infant, Newborn; Infant, Small for Gestational Age; Perinatal Death; Platel | 2017 |
4 trials available for aspirin and Neonatal Death
| Article | Year |
|---|---|
The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries.
Topics: Aspirin; Female; Humans; Infant, Newborn; Malaria; Perinatal Death; Perinatal Mortality; Pregnancy; | 2022 |
Aspirin delays the onset of hypertensive disorders of pregnancy among nulliparous pregnant women: A secondary analysis of the ASPIRIN trial.
Topics: Aspirin; Child; Child Health; Female; Fetal Growth Retardation; Humans; Hypertension, Pregnancy-Indu | 2023 |
The impact of risk factors on aspirin's efficacy for the prevention of preterm birth.
Topics: Aspirin; Female; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Male; Perinatal Death; Pr | 2023 |
Rate of Gestational Diabetes Mellitus and Pregnancy Outcomes in Patients with Chronic Hypertension.
Topics: Adult; Aspirin; Diabetes, Gestational; Female; Gestational Age; Humans; Hypertension; Infant, Newbor | 2016 |
2 other studies available for aspirin and Neonatal Death
| Article | Year |
|---|---|
Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: US Preventive Services Task Force Recommendation Statement.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Infant, Newborn; Infant, Small for | 2021 |
Cost-effectiveness of low-dose aspirin for the prevention of preterm birth: a prospective study of the Global Network for Women's and Children's Health Research.
Topics: Aspirin; Child; Child Health; Cost-Benefit Analysis; Female; Humans; Infant, Newborn; Perinatal Deat | 2023 |