Page last updated: 2024-10-23

aspirin and Myeloproliferative Disorders

aspirin has been researched along with Myeloproliferative Disorders in 66 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Myeloproliferative Disorders: Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.

Research Excerpts

ExcerptRelevanceReference
" From 1974 to 1986 we treated 20 symptomatic ET patients with microvascular circulation disturbances including erythromelalgia (N = 18), atypical or typical transient ischemic attacks (N = 6), or acute coronary ischemic syndrome (N = 3) with aspirin and one course of busulfan."9.09Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia. ( Michiels, JJ, 1999)
"In myeloproliferative neoplasms (MPNs), the immature platelet fraction (IPF) rises due to enhanced platelet turnover, and this has been thought to reduce the efficacy of aspirin."5.91Myeloproliferative Neoplasms and Aspirin: Does Increased Platelet Turnover Matter? ( Akay, OM; Erdoğan Özünal, I; Göktürk, A; Kaya, AH; Koçak Göktürk, I; Öztürk, E; Yılmaz, G, 2023)
"Retroperitoneal hematoma is a rare complication of psoas catheter placement, typically occurring several days after placement and in the setting of anticoagulation."5.43Acute Retroperitoneal Hematoma After Psoas Catheter Placement in a Patient with Myeloproliferative Thrombocytosis and Aspirin Therapy. ( Duncan, CM; Kopp, SL; Warner, NS, 2016)
" From 1974 to 1986 we treated 20 symptomatic ET patients with microvascular circulation disturbances including erythromelalgia (N = 18), atypical or typical transient ischemic attacks (N = 6), or acute coronary ischemic syndrome (N = 3) with aspirin and one course of busulfan."5.09Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia. ( Michiels, JJ, 1999)
"Aspirin has a well established role in the prevention of arterial thrombosis."4.79Aspirin in essential thrombocythemia: status quo and quo vadis. ( Bangerter, M; Griesshammer, M; Michiels, JJ; van Vliet, HH, 1997)
"Twenty-seven patients with chronic myeloproliferative disorders and in vitro evidence of platelet hyperactivity on whole blood platelet lumi-aggregometry were commenced on anti-platelet therapy comprising aspirin, clopidogrel, and/or odorless garlic and the studies were repeated to assess the efficacy of the therapeutic agent(s)."3.73Use of whole blood platelet lumi-aggregometry to optimize anti-platelet therapy in patients with chronic myeloproliferative disorders. ( Gemmell, R; Hartwell, T; Manoharan, A, 2006)
" The abnormalities were increased during episodes of clinical thrombosis and could be suppressed in two-thirds of cases by aspirin therapy."3.66Platelet and plasma beta thromboglobulin in myeloproliferative syndromes and secondary thrombocytosis. ( Allington, MJ; Boughton, BJ; King, A, 1978)
"Risk factors for hemorrhage are less well defined than those for thrombosis."2.80Bleeding complications in BCR-ABL negative myeloproliferative neoplasms: prevalence, type, and risk factors in a single-center cohort. ( Gao, J; Kander, EM; McMahon, BJ; Raza, S; Stein, BL; Zakarija, A; Zhou, Z, 2015)
"Myeloproliferative neoplasms (MPNs) are increasingly being identified in women of childbearing potential."2.61Association of Treatments for Myeloproliferative Neoplasms During Pregnancy With Birth Rates and Maternal Outcomes: A Systematic Review and Meta-analysis. ( Fazelzad, R; Gupta, V; Kazi, S; Malinowski, AK; Maze, D; Shah, PS; Shehata, N, 2019)
"Age and history of thrombosis are the criteria used to stratify patients to the most appropriate therapeutic options."2.46JAK2 mutation and thrombosis in the myeloproliferative neoplasms. ( Vannucchi, AM, 2010)
"Placental infarction due to thrombosis seems to be the most consistent event."2.40Fertility, pregnancy and the management of myeloproliferative disorders. ( Bergmann, L; Griesshammer, M; Pearson, T, 1998)
"Bleeding and thrombosis are major causes of morbidity and mortality in patients with myeloproliferative disorders."2.37Bleeding and thrombosis in the myeloproliferative disorders. ( Schafer, AI, 1984)
"In myeloproliferative neoplasms (MPNs), the immature platelet fraction (IPF) rises due to enhanced platelet turnover, and this has been thought to reduce the efficacy of aspirin."1.91Myeloproliferative Neoplasms and Aspirin: Does Increased Platelet Turnover Matter? ( Akay, OM; Erdoğan Özünal, I; Göktürk, A; Kaya, AH; Koçak Göktürk, I; Öztürk, E; Yılmaz, G, 2023)
"Aspirin resistance was assessed using whole blood MEA (Multiplate®, Roche Diagnostics, Meylan, France)."1.48Decreased turnover aspirin resistance by bidaily aspirin intake and efficient cytoreduction in myeloproliferative neoplasms. ( Galinat, H; Ianotto, JC; Lippert, E; Mingant, F; Perrier-Cornet, A; Perrot, M, 2018)
"Retroperitoneal hematoma is a rare complication of psoas catheter placement, typically occurring several days after placement and in the setting of anticoagulation."1.43Acute Retroperitoneal Hematoma After Psoas Catheter Placement in a Patient with Myeloproliferative Thrombocytosis and Aspirin Therapy. ( Duncan, CM; Kopp, SL; Warner, NS, 2016)
"The myeloproliferative disorders have been the "poor cousins" in the family of hematological malignancies for some time."1.33Platelets and thrombosis in myeloproliferative diseases. ( Harrison, CN, 2005)
"Bleeding and thrombosis are well known major causes of morbidity and mortality in patients with myeloproliferative disorders (MPD) but the relationship between these clinical events and the commonly found platelet function abnormalities have not been established."1.27Platelet function in myeloproliferative disorders: characterization and sequential studies show multiple platelet abnormalities, and change with time. ( Baker, RI; Manoharan, A, 1988)

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199022 (33.33)18.7374
1990's12 (18.18)18.2507
2000's8 (12.12)29.6817
2010's17 (25.76)24.3611
2020's7 (10.61)2.80

Authors

AuthorsStudies
Goulart, H1
Mascarenhas, J2
Tremblay, D1
Edahiro, Y1
Koçak Göktürk, I1
Erdoğan Özünal, I1
Göktürk, A1
Kaya, AH1
Yılmaz, G1
Akay, OM1
Öztürk, E1
Lucijanic, M1
Skelin, M1
Kusec, R1
Maze, D1
Kazi, S1
Gupta, V1
Malinowski, AK1
Fazelzad, R1
Shah, PS1
Shehata, N1
Barbui, T8
Ghirardi, A1
Vannucchi, AM2
Marchetti, M2
De Stefano, V2
Lucchesi, A1
Carloni, S1
De Matteis, S1
Ghetti, M1
Musuraca, G1
Poggiaspalla, M1
Augello, AF1
Giordano, G1
Fattori, PP1
Martinelli, G1
Napolitano, R1
Xie, J1
Geng, L1
Yuan, B1
Guo, Y1
Zhang, Z1
Gangat, N1
Tefferi, A1
Liyanapthirana, C1
Neal, R1
Iordanov, T1
Nahhas, A1
Usui, N1
Perrier-Cornet, A1
Ianotto, JC2
Mingant, F2
Perrot, M1
Lippert, E2
Galinat, H2
Finazzi, G3
Stolyar, MA1
Ivashin, DS1
Olkhovsky, IA1
Lew, J1
Frucht, SJ1
Kremyanskaya, M1
Hoffman, R1
Lavi, N1
Brenner, B1
Avivi, I1
Robier, C2
Stettin, M2
Neubauer, M2
Quehenberger, F1
Neumeister, P1
Alvarez-Larrán, A1
Besses, C1
Kander, EM1
Raza, S1
Zhou, Z1
Gao, J1
Zakarija, A1
McMahon, BJ1
Stein, BL1
Warner, NS1
Duncan, CM1
Kopp, SL1
Gillet, B1
Didier, R1
Gilard, M1
Ugo, V1
Bain, BJ1
Baud, P1
Tobler, A1
Lämmle, B1
Alberio, L1
Spivak, JL1
Barosi, G1
Tognoni, G1
Marchioli, R2
Harrison, CN1
Landolfi, R2
Di Gennaro, L1
Novarese, L1
Patrono, C1
Eikelboom, J1
Manoharan, A2
Gemmell, R1
Hartwell, T1
Viero, P3
Cortelazzo, S3
Bassan, R1
Ireland, H1
Lane, DA1
Wolff, S1
Foadi, M1
de Gaetano, G3
Schafer, AI1
Boughton, BJ2
Jerrome, DW1
Rychetnik, M1
Meschengieser, SS1
Woods, AI1
Schattner, MA1
Lazzari, MA1
Phadke, K1
Dean, S1
Pitney, WR1
Sidorova, LD1
Arkhipov, BF1
Degtiareva, MM1
Barkagan, LZ1
Salem, HH1
van der Weyden, MB1
Koutts, J1
Firkin, BG1
Mughal, TI1
Matsumoto, H1
Michiels, JJ5
van Genderen, PJ3
Jansen, PH1
Koudstaal, PJ1
Leenknegt, H1
Budde, U1
Dapling, RB1
Snowden, JA1
West, J1
Talbot, JF1
Nelson, ME1
Greaves, M1
Griesshammer, M3
Bangerter, M1
van Vliet, HH1
Wehmeier, A2
Südhoff, T1
Meierkord, F1
Kutti, J1
Stark, P1
Bazzan, M1
Gugliotta, L1
Brière, J2
Kiladjian, JJ1
Berlin, NI1
Pearson, TC1
Green, AC1
Fruchtmann, SM1
Silver, RT1
Hansmann, E1
Lengfelder, E1
Kvasnicka, HM1
Hasselbalch, H1
Cervantes, F1
Thiele, J1
Bergmann, L1
Pearson, T1
Allington, MJ1
King, A1
Okuma, M2
Uchino, H1
Boss, GR1
Seegmiller, JE1
Gordon, DH1
Schaffner, D1
Bennett, JM1
Schwartz, SI1
Zieve, PD1
Levin, J1
Levesque, H1
Cailleux, N1
Courtois, H1
Goldstein, R1
Clark, P1
Klintmalm, G1
Husberg, B1
Gonwa, T1
Stone, M1
Luzzatto, G1
Fabris, F1
Mazzucato, M1
Girolami, A1
Niikura, H1
Baker, RI1
Buelli, M1
Weiss, HJ1
Neemeh, JA1
Bowie, EJ1
Thompson, JH1
Didisheim, P1
Owen, CA1

Reviews

23 reviews available for aspirin and Myeloproliferative Disorders

ArticleYear
Low-risk polycythemia vera and essential thrombocythemia: management considerations and future directions.
    Annals of hematology, 2022, Volume: 101, Issue:5

    Topics: Aspirin; Humans; Myeloproliferative Disorders; Polycythemia Vera; Primary Myelofibrosis; Quality of

2022
Treatment options and pregnancy management for patients with PV and ET.
    International journal of hematology, 2022, Volume: 115, Issue:5

    Topics: Aspirin; Female; Humans; Hydroxyurea; Janus Kinase 2; Janus Kinase Inhibitors; Myeloproliferative Di

2022
Association of Treatments for Myeloproliferative Neoplasms During Pregnancy With Birth Rates and Maternal Outcomes: A Systematic Review and Meta-analysis.
    JAMA network open, 2019, 10-02, Volume: 2, Issue:10

    Topics: Antineoplastic Agents; Aspirin; Birth Rate; Female; Fibrinolytic Agents; Heparin; Humans; Interferon

2019
Myeloproliferative neoplasms and pregnancy: Overview and practice recommendations.
    American journal of hematology, 2021, 03-01, Volume: 96, Issue:3

    Topics: Abortion, Habitual; Abortion, Spontaneous; Anticoagulants; Aspirin; Combined Modality Therapy; Femal

2021
Antiplatelet therapy in the management of myeloproliferative neoplasms.
    Current hematologic malignancy reports, 2014, Volume: 9, Issue:4

    Topics: Aspirin; Disease Management; Female; Humans; Male; Myeloproliferative Disorders; Platelet Aggregatio

2014
JAK2 mutation and thrombosis in the myeloproliferative neoplasms.
    Current hematologic malignancy reports, 2010, Volume: 5, Issue:1

    Topics: Amino Acid Substitution; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Fibrinolytic Ag

2010
Chronic myeloproliferative disorders.
    Hematology. American Society of Hematology. Education Program, 2003

    Topics: Antineoplastic Agents; Aspirin; Cardiovascular Diseases; Chronic Disease; Hematopoietic Stem Cell Tr

2003
Aspirin for the control of platelet activation and prevention of thrombosis in essential thrombocythemia and polycythemia vera: current insights and rationale for future studies.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:3

    Topics: Aspirin; Humans; Myeloproliferative Disorders; Platelet Activation; Polycythemia Vera; Thrombocythem

2006
Aspirin resistance: does it exist and is it an important clinical problem?
    Clinical advances in hematology & oncology : H&O, 2006, Volume: 4, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidog

2006
Platelets, prostaglandins and thrombotic disorders.
    Clinics in haematology, 1981, Volume: 10, Issue:2

    Topics: Arachidonic Acids; Arteriosclerosis; Aspirin; Blood Platelets; Calcium; Coronary Disease; Cyclic AMP

1981
Bleeding and thrombosis in the myeloproliferative disorders.
    Blood, 1984, Volume: 64, Issue:1

    Topics: Alkylating Agents; Arachidonic Acids; Aspirin; Blood Viscosity; Epinephrine; Hematocrit; Hemorrhage;

1984
Primary thrombocythemia: a current perspective.
    Stem cells (Dayton, Ohio), 1995, Volume: 13, Issue:4

    Topics: Aspirin; Diagnosis, Differential; Humans; Hydroxyurea; Interferon Type I; Myeloproliferative Disorde

1995
[Erythromelalgia--review of clinical characteristics and therapy].
    No to shinkei = Brain and nerve, 1993, Volume: 45, Issue:11

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Erythromelalgia; F

1993
Atypical transient ischemic attacks in thrombocythemia of various myeloproliferative disorders.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Adult; Aged; Aspirin; Capillaries; Cerebral Arteries; Diagnosis, Differential; Erythromelalgia; Fema

1996
Acquired von Willebrand disease in myeloproliferative disorders.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Aspirin; Autoantibodies; Bleeding Time; Contraindications; Humans; Myeloproliferative Disorders; Pla

1996
Aspirin in essential thrombocythemia: status quo and quo vadis.
    Seminars in thrombosis and hemostasis, 1997, Volume: 23, Issue:4

    Topics: Abortion, Habitual; Aspirin; Cerebrovascular Disorders; Cohort Studies; Contraindications; Erythrome

1997
Relation of platelet abnormalities to thrombosis and hemorrhage in chronic myeloproliferative disorders.
    Seminars in thrombosis and hemostasis, 1997, Volume: 23, Issue:4

    Topics: Alkylating Agents; Arachidonic Acid; Aspirin; Bleeding Time; Blood Platelets; Bone Marrow; Hematopoi

1997
Diagnosis, pathogenesis and treatment of the myeloproliferative disorders essential thrombocythemia, polycythemia vera and essential megakaryocytic granulocytic metaplasia and myelofibrosis.
    The Netherlands journal of medicine, 1999, Volume: 54, Issue:2

    Topics: Aspirin; Bone Marrow; Bone Marrow Transplantation; Diagnosis, Differential; Follow-Up Studies; Granu

1999
Fertility, pregnancy and the management of myeloproliferative disorders.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Alkylating Agents; Animals; Aspirin; Bone Marrow

1998
Hyperuricemia and gout. Classification, complications and management.
    The New England journal of medicine, 1979, Jun-28, Volume: 300, Issue:26

    Topics: Acute Disease; Allopurinol; Arthritis; Aspirin; Colchicine; Coronary Disease; Diuretics; Gout; Human

1979
Qualitative disorders of platelets.
    Major problems in internal medicine, 1976, Volume: 10

    Topics: Aspirin; Blood Coagulation Tests; Blood Platelet Disorders; Humans; Myeloproliferative Disorders

1976
[Thrombosis in various diseases: myeloproliferative disorders].
    Nihon rinsho. Japanese journal of clinical medicine, 1986, Volume: 44, Issue:5

    Topics: Aspirin; beta-Thromboglobulin; Blood Coagulation Factors; Busulfan; Carbazilquinone; Dipyridamole; H

1986
Bleeding disorders due to abnormal platelet function.
    The Medical clinics of North America, 1973, Volume: 57, Issue:2

    Topics: Adenosine Diphosphate; Aspirin; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Fa

1973

Trials

2 trials available for aspirin and Myeloproliferative Disorders

ArticleYear
Bleeding complications in BCR-ABL negative myeloproliferative neoplasms: prevalence, type, and risk factors in a single-center cohort.
    International journal of hematology, 2015, Volume: 102, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Female; Fusion Proteins, bcr-abl;

2015
Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 1999, Volume: 5, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Busulfan; Coronary Disease; Dise

1999

Other Studies

41 other studies available for aspirin and Myeloproliferative Disorders

ArticleYear
Myeloproliferative Neoplasms and Aspirin: Does Increased Platelet Turnover Matter?
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2023, 02-28, Volume: 40, Issue:1

    Topics: Aspirin; Blood Platelets; Humans; Hydroxyurea; Myeloproliferative Disorders; Neoplasms

2023
Second primary malignancies in myeloproliferative neoplasms and the role of aspirin.
    Leukemia, 2019, Volume: 33, Issue:10

    Topics: Aspirin; Humans; Myeloproliferative Disorders; Neoplasms, Second Primary; Platelet Aggregation

2019
Reply to: Second primary malignancies in myeloproliferative neoplasms and the role of aspirin.
    Leukemia, 2020, Volume: 34, Issue:4

    Topics: Aspirin; Humans; Myeloproliferative Disorders; Neoplasms, Second Primary; Platelet Aggregation

2020
Unexpected low expression of platelet fibrinogen receptor in patients with chronic myeloproliferative neoplasms: how does it change with aspirin?
    British journal of haematology, 2020, Volume: 189, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Chronic Disease; Fibrinogen; Humans; Middl

2020
Complex intracranial vascular complications caused by essential thrombocythemia: a critical case report.
    BMC neurology, 2020, Nov-07, Volume: 20, Issue:1

    Topics: Adult; Aspirin; Blood Platelets; Female; Hemorrhage; Humans; Magnetic Resonance Imaging; Mutation; M

2020
A rare consequence of very common osteoporotic pubic rami fracture in a patient with myeloproliferative disease.
    BMJ case reports, 2017, Jul-17, Volume: 2017

    Topics: Accidental Falls; Aged, 80 and over; Aspirin; Blood Transfusion; Female; Fractures, Bone; Hematoma;

2017
JSH guideline for tumors of hematopoietic and lymphoid tissues-lukemia: 4. Chronic myelogenous leukemia (CML)/myeloproliferative neoplasms (MPN).
    International journal of hematology, 2017, Volume: 106, Issue:5

    Topics: Algorithms; Aniline Compounds; Antineoplastic Agents; Aspirin; Blood Transfusion; Dasatinib; Hematop

2017
Decreased turnover aspirin resistance by bidaily aspirin intake and efficient cytoreduction in myeloproliferative neoplasms.
    Platelets, 2018, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Biomarkers; Blood Platelets; Drug Resistance; F

2018
Antithrombotic therapy for venous thromboembolism in myeloproliferative neoplasms.
    Blood cancer journal, 2018, 06-26, Volume: 8, Issue:7

    Topics: Anticoagulants; Aspirin; Fibrinolytic Agents; Heparin; Humans; Myeloproliferative Disorders; Recurre

2018
[ON THE ISSUE OF SELECTION OF COAGULANTS UNDER ADP-INDUCED IMPEDANCE TEST OF AGGREGATION OF THROMBOCYTES IN PATIENTS WITH CHRONIC MYELO-PROLIFERATIVE TUMORS].
    Klinicheskaia laboratornaia diagnostika, 2017, Volume: 62, Issue:3

    Topics: Adenosine Triphosphate; Adult; Aged; Anticoagulants; Aspirin; Blood Platelets; Citrates; Electric Im

2017
Hemichorea in a patient with JAK2V617F blood cells.
    Blood, 2013, Feb-14, Volume: 121, Issue:7

    Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Aspirin; Chorea; Female; Humans; Hydroxyurea; Janu

2013
Management of pregnant women with myeloproliferative neoplasms.
    Thrombosis research, 2013, Volume: 131 Suppl 1

    Topics: Adult; Aspirin; Blood Viscosity; Female; Gestational Age; Heparin, Low-Molecular-Weight; Humans; Inc

2013
Changes in response to antiaggregatory treatment in patients with myeloproliferative neoplasms: a sequential study using multiple electrode aggregometry.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2013, Volume: 24, Issue:8

    Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Case-Control Studies

2013
Assessment of the response to acetylsalicylic acid in patients with myeloproliferative neoplasms by whole blood assays: a comparison of the PFA-100 with multiple electrode aggregometry.
    Platelets, 2014, Volume: 25, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Biological Assay; Blood Platelets; Female; Humans; Male; Mi

2014
Acute Retroperitoneal Hematoma After Psoas Catheter Placement in a Patient with Myeloproliferative Thrombocytosis and Aspirin Therapy.
    A & A case reports, 2016, Jan-15, Volume: 6, Issue:2

    Topics: Aged, 80 and over; Aspirin; Catheters; Gastrointestinal Hemorrhage; Hematoma; Humans; Male; Myelopro

2016
Multiple Electrode Aggregometry is an adequate method for aspirin response testing in myeloproliferative neoplasms and differentiates the mechanisms of aspirin resistance.
    Thrombosis research, 2016, Volume: 142

    Topics: Adult; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Blood Platelets; Drug Resistance; Electro

2016
How to manage children and young adults with myeloproliferative neoplasms.
    Leukemia, 2012, Volume: 26, Issue:7

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antiviral Agents;

2012
Bone marrow biopsy morbidity and mortality.
    British journal of haematology, 2003, Volume: 121, Issue:6

    Topics: Anticoagulants; Aspirin; Biopsy, Needle; Bone Marrow Examination; Hemorrhage; Humans; Myeloprolifera

2003
Acquired von Willebrand syndrome in a myeloproliferative disorder. Case 6.
    Hamostaseologie, 2003, Volume: 23, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Male; Middle Aged; Myeloproliferative Diso

2003
Platelets and thrombosis in myeloproliferative diseases.
    Hematology. American Society of Hematology. Education Program, 2005

    Topics: Aspirin; Blood Platelets; Clinical Trials as Topic; Endothelium, Vascular; Hematocrit; Humans; Janus

2005
Use of whole blood platelet lumi-aggregometry to optimize anti-platelet therapy in patients with chronic myeloproliferative disorders.
    American journal of hematology, 2006, Volume: 81, Issue:9

    Topics: Aspirin; Chronic Disease; Clopidogrel; Dietary Supplements; Dose-Response Relationship, Drug; Garlic

2006
Effect of aspirin on platelet 5-hydroxytryptamine and beta-thromboglobulin plasma levels in patients with myeloproliferative diseases.
    Thrombosis and haemostasis, 1982, Oct-29, Volume: 48, Issue:2

    Topics: Adult; Aged; Aspirin; Beta-Globulins; beta-Thromboglobulin; Blood Platelets; Female; Humans; Leukemi

1982
In vivo platelet release in myeloproliferative disorders.
    Thrombosis and haemostasis, 1982, Aug-24, Volume: 48, Issue:1

    Topics: Aged; Aspirin; beta-Thromboglobulin; Blood Platelets; Fibrinopeptide A; Fibrinopeptide B; Humans; Mi

1982
Chronic myeloproliferative disorders: a quantitative assessment of platelet ultrastructure.
    Acta haematologica, 1980, Volume: 64, Issue:6

    Topics: Aspirin; Blood Platelets; Chronic Disease; Cytoplasmic Granules; Humans; Myeloproliferative Disorder

1980
[Association of hemorrhagic and thrombotic phenomena in myeloproliferative syndromes].
    Medicina, 1981, Volume: 41 Suppl

    Topics: Adult; Aspirin; Blood Platelet Disorders; Dipyridamole; Female; Humans; Leukemia, Myeloid; Male; Mid

1981
Platelet dysfunction in myeloproliferative syndromes.
    American journal of hematology, 1981, Volume: 10, Issue:1

    Topics: Aspirin; Blood Platelets; Humans; Malondialdehyde; Mathematics; Myeloproliferative Disorders; Platel

1981
[Hemostasis disorders and their treatment in patients with chronic myeloproliferative diseases].
    Terapevticheskii arkhiv, 1981, Volume: 53, Issue:9

    Topics: Aged; Aspirin; Chronic Disease; Hemorrhagic Disorders; Humans; Male; Myeloproliferative Disorders; P

1981
Leg pain and platelet aggregates in thrombocythemic myeloproliferative disease.
    JAMA, 1980, Sep-05, Volume: 244, Issue:10

    Topics: Aged; Aspirin; Female; Foot; Humans; Ischemia; Male; Microcirculation; Middle Aged; Myeloproliferati

1980
The microvasculature in myeloproliferative disease. A study using retinal fluorescein angiography.
    Clinical and laboratory haematology, 1996, Volume: 18, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Allergens; Antineoplastic Agents; Arterial Occlusive Diseases; Aspir

1996
Myeloproliferative syndromes. Current opinions from the European Hematology Association Working Group on Myeloproliferative Disorders.
    Pathologie-biologie, 2001, Volume: 49, Issue:2

    Topics: Aspirin; Bone Marrow Examination; Clinical Trials as Topic; Clone Cells; Congresses as Topic; Diseas

2001
Platelet and plasma beta thromboglobulin in myeloproliferative syndromes and secondary thrombocytosis.
    British journal of haematology, 1978, Volume: 40, Issue:1

    Topics: Aspirin; Beta-Globulins; Blood Platelets; Female; Humans; Male; Myeloproliferative Disorders; Thromb

1978
Altered arachidonate metabolism by platelets in patients with myeloproliferative disorders.
    Blood, 1979, Volume: 54, Issue:6

    Topics: Adult; Aged; Arachidonic Acids; Aspirin; Blood Platelets; Female; Humans; Lipoxygenase; Male; Middle

1979
Postsplenectomy thrombocytosis: its association with mesenteric, portal, and/or renal vein thrombosis in patients with myeloproliferative disorders.
    Archives of surgery (Chicago, Ill. : 1960), 1978, Volume: 113, Issue:6

    Topics: Aged; Aspirin; Female; Heparin; Humans; Male; Middle Aged; Myeloproliferative Disorders; Preoperativ

1978
[Erythromelalgia in adults. Apropos of 16 cases].
    Revue du rhumatisme et des maladies osteo-articulaires, 1992, Volume: 59, Issue:4

    Topics: Adult; Aspirin; Erythromelalgia; Female; Humans; Male; Middle Aged; Myeloproliferative Disorders

1992
Prevention of recurrent thrombosis following liver transplantation for Budd-Chiari syndrome associated with myeloproliferative disorders: treatment with hydroxyurea and aspirin.
    Transplantation proceedings, 1991, Volume: 23, Issue:1 Pt 2

    Topics: Adult; Aspirin; Budd-Chiari Syndrome; Female; Humans; Hydroxyurea; Liver Transplantation; Male; Myel

1991
PF 4 versus beta TG as evidence for platelet activation in myeloproliferative disorders.
    Scandinavian journal of haematology, 1985, Volume: 35, Issue:3

    Topics: Adult; Age Factors; Aged; Aspirin; Beta-Globulins; beta-Thromboglobulin; Dipyridamole; Female; Human

1985
Platelet function in myeloproliferative disorders: characterization and sequential studies show multiple platelet abnormalities, and change with time.
    European journal of haematology, 1988, Volume: 40, Issue:3

    Topics: Aged; Aspirin; Blood Platelet Disorders; Blood Platelets; Female; Follow-Up Studies; Hemorrhage; Hum

1988
Aspirin and risk of bleeding in patients with thrombocythemia.
    The American journal of medicine, 1987, Volume: 83, Issue:2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adolescent; Adult; Aged; Aspirin; Bleeding Time; Blood P

1987
Defective platelet aggregation induced by platelet activating factor in myeloproliferative disorders: deficiency of an aspirin-independent mechanism?
    Haemostasis, 1986, Volume: 16, Issue:1

    Topics: Adult; Aged; Aspirin; Drug Synergism; Epinephrine; Female; Humans; In Vitro Techniques; Male; Middle

1986
[Arachidonic acids].
    Rinsho byori. The Japanese journal of clinical pathology, 1985, Volume: Spec No 62

    Topics: Arachidonic Acids; Aspirin; Blood Platelets; Diabetes Mellitus; Humans; Methods; Myeloproliferative

1985
Quantitation of platelet aggregation in myeloproliferative disorders.
    American journal of clinical pathology, 1972, Volume: 57, Issue:3

    Topics: Absorption; Adenosine Diphosphate; Aspirin; Collagen; Densitometry; Epinephrine; Humans; Light; Meth

1972