Page last updated: 2024-10-23

aspirin and Musculoskeletal Pain

aspirin has been researched along with Musculoskeletal Pain in 5 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Musculoskeletal Pain: Discomfort stemming from muscles, LIGAMENTS, tendons, and bones.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study is to investigate if an orally administered combination of aspirin and ketamine will provide better analgesia than a ketamine alone in adult patients presenting to the Emergency Department (ED) with acute musculoskeletal pain."9.51Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain. ( Barberan, C; Correa Bravo, S; Davis, A; Drapkin, J; Fassassi, C; Gerges, L; Gohel, A; Hossain, R; Likourezos, A; Motov, S; Niceforo, P; Silver, M, 2022)
"The purpose of this study is to investigate if an orally administered combination of aspirin and ketamine will provide better analgesia than a ketamine alone in adult patients presenting to the Emergency Department (ED) with acute musculoskeletal pain."5.51Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain. ( Barberan, C; Correa Bravo, S; Davis, A; Drapkin, J; Fassassi, C; Gerges, L; Gohel, A; Hossain, R; Likourezos, A; Motov, S; Niceforo, P; Silver, M, 2022)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Davis, A2
Fassassi, C2
Dove, D1
Drapkin, J2
Likourezos, A2
Gohel, A2
Favale, P1
Hossain, R2
Butt, M1
Gerges, L2
Motov, S2
Barberan, C1
Correa Bravo, S1
Silver, M1
Niceforo, P1
Topaz, M1
Lai, K1
Dhopeshwarkar, N1
Seger, DL1
Sa'adon, R1
Goss, F1
Rozenblum, R1
Zhou, L1
RAMUNIS, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Analgesic Efficacy of Orally Administered VTS-K (Liquid Oral Ketamine Taken Simultaneously With VTS-Aspirin) for Pain Management of Adult ED Patients Presenting to the ED With Acute Musculoskeletal Pain[NCT04702555]25 participants (Actual)Observational2021-01-08Completed
A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone in Adult Patients Presenting to the ED With Acute Musculoskeletal Pain: Prospective, Randomized, Open-Label, Clinical Trial.[NCT04860804]Phase 460 participants (Actual)Interventional2021-04-22Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Reduction in Pain Score at 60 Minutes

Reduction of pain scores on numeric rating pain scale (NRS) at 60 minutes mark form the baseline. The NRS is an 11 item Likert Scale ranging from 0 (no pain) to 10 (very severe pain) with 5 indicating moderate pain. (NCT04860804)
Timeframe: 60 minutes

Interventionunits on a scale (Mean)
AOK Group2.18
OK Group4.01

Trials

1 trial available for aspirin and Musculoskeletal Pain

ArticleYear
Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain.
    The American journal of emergency medicine, 2022, Volume: 58

    Topics: Acute Pain; Adult; Analgesics; Aspirin; Double-Blind Method; Emergency Service, Hospital; Humans; Ke

2022

Other Studies

4 other studies available for aspirin and Musculoskeletal Pain

ArticleYear
Analgesic Efficacy of Oral Aspirin/Ketamine Combination for Management of Acute Musculoskeletal Pain in the Emergency Department - A Proof of Concept Pilot Study.
    The Journal of emergency medicine, 2022, Volume: 62, Issue:6

    Topics: Acute Pain; Adult; Analgesics; Aspirin; Double-Blind Method; Emergency Service, Hospital; Humans; Ke

2022
Orphengesic Forte - an old analgesic combination returns.
    The Medical letter on drugs and therapeutics, 2020, 11-16, Volume: 62, Issue:1611

    Topics: Analgesics; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Drug Interactions; Human

2020
Clinicians' Reports in Electronic Health Records Versus Patients' Concerns in Social Media: A Pilot Study of Adverse Drug Reactions of Aspirin and Atorvastatin.
    Drug safety, 2016, Volume: 39, Issue:3

    Topics: Adverse Drug Reaction Reporting Systems; Aspirin; Atorvastatin; Drug-Related Side Effects and Advers

2016
Investigation of phenyramidol for relief of musculoskeletal pain in an industrial population.
    Clinical medicine (Northfield, Ill.), 1963, Volume: 70

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Muscle Relaxants, Central; Musculoskele

1963