aspirin has been researched along with Muscle Relaxation in 32 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adjuvant arthritis was induced in rats with and without prophylactic losartan (AT1R antagonist) treatment." | 3.79 | Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis. ( Dunning, L; Ferrell, WR; Lockhart, JC; Mackenzie, A, 2013) |
| " Aspirin, indomethacin, and ONO 3708, a PG receptor antagonist, markedly inhibited the hypoxia-induced contraction, whereas superoxide dismutase and OKY 046, a thromboxane (Tx) A2 synthesis inhibitor, were ineffective." | 3.68 | Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries. ( Matsumoto, T; Toda, N; Yoshida, K, 1992) |
| "Pretreatment with methylene blue (10(-5) M) also caused a significant reduction of the SNP-induced relaxations in the precontracted thoracic ducts." | 1.28 | Acetylcholine-induced release of endothelium-derived relaxing factor from lymphatic endothelial cells. ( Ohhashi, T; Takahashi, N, 1991) |
| "Treatment with eperisone attenuated the contractions induced by norepinephrine and serotonin in the arteries and those by clonidine and phenylephrine in the veins." | 1.28 | Mechanisms of action of eperisone on isolated dog saphenous arteries and veins. ( Bian, K; Inoue, S; Okamura, T; Okunishi, H; Toda, N, 1989) |
| "Dipyridamole appears to increase the production of PGI2 even in the presence of PG synthesis inhibition by aspirin or indomethacin." | 1.27 | Modification of angiotensin II-induced relaxation by dipyridamole, phthalazinol and aspirin in isolated dog renal arteries. ( Toda, N; Yamamoto, M, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (46.88) | 18.7374 |
| 1990's | 12 (37.50) | 18.2507 |
| 2000's | 3 (9.38) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, KS | 1 |
| Ko, FN | 1 |
| Teng, CM | 1 |
| Wu, YC | 1 |
| Lazzarato, L | 1 |
| Chegaev, K | 1 |
| Marini, E | 1 |
| Rolando, B | 1 |
| Borretto, E | 1 |
| Guglielmo, S | 1 |
| Joseph, S | 1 |
| Di Stilo, A | 1 |
| Fruttero, R | 1 |
| Gasco, A | 1 |
| Mackenzie, A | 1 |
| Dunning, L | 1 |
| Ferrell, WR | 1 |
| Lockhart, JC | 1 |
| Tarumi, T | 1 |
| Shirahase, H | 1 |
| Kanda, M | 1 |
| Nakamura, S | 1 |
| Kurahashi, K | 1 |
| Toda, N | 4 |
| Yamamoto, M | 1 |
| Bettini, V | 1 |
| Gamba, G | 1 |
| Legrenzi, E | 1 |
| Libardoni, C | 1 |
| Mayellaro, F | 1 |
| Gerritsen, ME | 1 |
| Morgan, DO | 1 |
| Parks, TP | 1 |
| Printz, MP | 1 |
| Lederis, KP | 1 |
| Herbaczynska-Cedro, K | 1 |
| Truskolaski, P | 1 |
| Huszczuk, A | 1 |
| Dusting, GJ | 1 |
| Prancan, A | 1 |
| Lefort, J | 1 |
| Barton, M | 1 |
| Vargaftig, BB | 1 |
| Mizuno, R | 2 |
| Ohhashi, T | 5 |
| Moroi, M | 1 |
| Akatsuka, N | 2 |
| Fukazawa, M | 1 |
| Hara, K | 1 |
| Ishikawa, M | 1 |
| Aikawa, J | 1 |
| Namiki, A | 2 |
| Yamaguchi, T | 1 |
| Fukushima, S | 1 |
| Diehl, B | 1 |
| Hoheisel, U | 1 |
| Mense, S | 1 |
| Wang, JX | 1 |
| Ikomi, F | 1 |
| Wang, H | 1 |
| Sipahi, E | 1 |
| Ercan, ZS | 3 |
| Türker, RK | 3 |
| Sipahi, EY | 1 |
| Pieper, GM | 1 |
| Siebeneich, W | 1 |
| Olds, CL | 1 |
| Felix, CC | 1 |
| Del Soldato, P | 1 |
| Ersoy, FF | 1 |
| Bor, N | 1 |
| Swies, J | 1 |
| Radomski, M | 1 |
| Gryglewski, RJ | 1 |
| Ishihara, Y | 1 |
| Yotsumoto, K | 1 |
| Sasaki, K | 1 |
| Kudoh, S | 1 |
| Kitamura, S | 1 |
| Kalsner, S | 1 |
| Matsumoto, T | 1 |
| Yoshida, K | 1 |
| Takahashi, N | 1 |
| Holden, WE | 1 |
| Kishiyama, SS | 1 |
| Dong, SP | 1 |
| Osborne, ML | 1 |
| Inoue, S | 1 |
| Bian, K | 1 |
| Okamura, T | 1 |
| Okunishi, H | 1 |
| Katsoulis, S | 1 |
| Conlon, JM | 1 |
| Bornfeldt, KE | 1 |
| Axelsson, KL | 1 |
| Tschirhart, E | 1 |
| Frossard, N | 1 |
| Bertrand, C | 1 |
| Landry, Y | 1 |
| Brunelleschi, S | 1 |
| Haye-Legrand, I | 1 |
| Labat, C | 1 |
| Norel, X | 1 |
| Benveniste, J | 1 |
| Brink, C | 1 |
32 other studies available for aspirin and Muscle Relaxation
| Article | Year |
|---|---|
Antiplatelet of vasorelaxing actions of some benzylisoquinoline and phenanthrene alkaloids.
Topics: Alkaloids; Animals; Aorta, Thoracic; Female; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, | 1996 |
New nitric oxide or hydrogen sulfide releasing aspirins.
Topics: Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Aspirin; Humans; Hydrogen Sulfide; Male; Muscle | 2011 |
Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Arthritis, Experimental; Aspirin; Charyb | 2013 |
Role of intracellular Ca2+ in endothelium-dependent contraction and relaxation of rabbit intrapulmonary arteries.
Topics: Animals; Aspirin; Calcimycin; Calcium; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Ionom | 2003 |
Modification of angiotensin II-induced relaxation by dipyridamole, phthalazinol and aspirin in isolated dog renal arteries.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Angiotensin II; Animals; Aspirin; Cyclooxygenase Inhibitors; Di | 1983 |
[Response of isolated coronary artery segments to serotonin in the presence of a flavinoid, indomethacin and acetylsalicylate].
Topics: Animals; Ascorbic Acid; Aspirin; Cattle; Coronary Vessels; Indomethacin; Muscle Contraction; Muscle | 1983 |
A proposed role for prostaglandins in the modulation of the relaxation response to urotensin I in isolated rat arteries.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Aspirin; Atropine; Dose-Response Relationshi | 1981 |
Different responsiveness of a variety of isolated dog arteries to prostaglandin D2.
Topics: Animals; Arteries; Aspirin; Cerebral Arteries; Coronary Vessels; Dinoprost; Dinoprostone; Dogs; Dose | 1982 |
Hypoventilation and elevation of end-expiratory pressure release a substance which relaxes isolated arteries and disaggregates platelets in the presence of cyclooxygenase inhibitors.
Topics: Animals; Aspirin; Biological Assay; Cats; Cattle; Dogs; Epoprostenol; Hypoventilation; Indomethacin; | 1981 |
Relaxation of the guinea-pig trachea induced by platelet-activating factor and by serotonin.
Topics: Acetylcholine; Animals; Aspirin; Blood Platelets; Female; Guinea Pigs; Histamine; In Vitro Technique | 1982 |
5-Hydroxytryptamine-induced NO-dependent relaxation in isolated strips of monkey popliteal lymph nodes.
Topics: Animals; Arginine; Aspirin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Ketanseri | 1995 |
Endothelium-dependent relaxation by angiotensin-converting enzyme inhibitors in canine femoral arteries.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Aspirin; Captopril; Dinoprost; Dipeptid | 1994 |
Acetylcholine-induced endothelium-independent relaxations in monkey isolated superior and inferior caval veins.
Topics: Acetylcholine; Animals; Arginine; Aspirin; Calcimycin; Dinoprost; Endothelium, Vascular; Female; Gly | 1993 |
The influence of mechanical stimuli and of acetylsalicylic acid on the discharges of slowly conducting afferent units from normal and inflamed muscle in the rat.
Topics: Action Potentials; Animals; Aspirin; Blood Pressure; Carrageenan; Female; Male; Muscle Relaxation; M | 1993 |
5-Hydroxytryptamine-induced endothelium-dependent and -independent relaxations in isolated dog anterior spinal small arteries.
Topics: Animals; Arteries; Aspirin; Dogs; Endothelium, Vascular; Epoprostenol; Female; Fibrinolytic Agents; | 1997 |
Macrophage-induced nitric oxide and prostanoid dependent relaxation of arterial smooth muscles.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arteries; Aspirin; Cells, Cultured; Dogs | 1997 |
Nitric oxide-mediated relaxation induced by bradykinin in the isolated mouse trachea.
Topics: Animals; Aspirin; Bradykinin; Carbachol; Female; Glycine; In Vitro Techniques; Male; Mice; Muscle Co | 1998 |
Nitric oxide and prostanoid-dependent relaxation induced by angiotensin II in the isolated precontracted mouse tracheal muscle and the role of potassium channels.
Topics: Angiotensin II; Animals; Aspirin; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Tech | 2000 |
Vascular protective actions of a nitric oxide aspirin analog in both in vitro and in vivo models of diabetes mellitus.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aspirin; Diabetes | 2002 |
The relaxing effects of angiotensin II and angiotensin III on canine isolated contracted tracheal muscle.
Topics: Acetylcholine; Angiotensin II; Angiotensin III; Animals; Aspirin; Dogs; In Vitro Techniques; Muscle | 1978 |
Angiotensin-induced release of prostacyclin (PGI2) into circulation of anaesthetized cats.
Topics: Anesthesia; Angiotensin II; Animals; Aspirin; Cats; Coronary Vessels; Epoprostenol; Female; Male; Mu | 1979 |
[Experimental investigation on the pathogenesis of aspirin-induced asthma--the effect of aspirin on the relaxation of guinea pig tracheal tissues with various bronchodilators (author's transl)].
Topics: Animals; Aspirin; Asthma; Bronchodilator Agents; Guinea Pigs; In Vitro Techniques; Male; Muscle Rela | 1978 |
Prostaglandin mediated relaxation of coronary artery strips under hypoxia.
Topics: Acetylcholine; Animals; Aspirin; Cattle; Coronary Vessels; In Vitro Techniques; Indomethacin; Muscle | 1978 |
Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries.
Topics: Animals; Aspirin; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Humans; Hypoxia; | 1992 |
Acetylcholine-induced release of endothelium-derived relaxing factor from lymphatic endothelial cells.
Topics: Acetylcholine; Animals; Arginine; Aspirin; Atropine; Dogs; Endothelium; Female; Male; Methylene Blue | 1991 |
Endothelium-dependent effects of cigarette smoke components on tone of porcine intrapulmonary arteries in vitro.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Endothelium, Vascular; Hexamethonium Compounds; In Vitr | 1990 |
Vascular smooth muscle relaxation induced by epidermal growth factor is endothelium-dependent.
Topics: Animals; Aorta, Thoracic; Aspirin; Atropine; Dinoprost; Endothelium, Vascular; Epidermal Growth Fact | 1990 |
Mechanisms of action of eperisone on isolated dog saphenous arteries and veins.
Topics: Animals; Arteries; Aspirin; Dogs; Drug Interactions; Electric Stimulation; Female; In Vitro Techniqu | 1989 |
Neurotensin and prostaglandin interactions in smooth muscle of the guinea pig stomach.
Topics: Animals; Apamin; Aspirin; Drug Interactions; Guinea Pigs; Muscle Contraction; Muscle Relaxation; Mus | 1988 |
Studies on the effect of different inhibitors of arachidonic acid metabolism on glyceryltrinitrate-induced relaxation and cGMP elevation in bovine vascular tissue.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Vessels; Cattle; Cyclic GMP; In Vitro Techniques; Masopro | 1987 |
Arachidonic acid metabolites and airway epithelium-dependent relaxant factor.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non | 1987 |
Platelet-activating factor-acether-induced relaxation of guinea pig airway muscle: role of prostaglandin E2 and the epithelium.
Topics: Acetylcholine; Animals; Aspirin; Dinoprostone; Epithelium; Guinea Pigs; Histamine; In Vitro Techniqu | 1987 |