aspirin has been researched along with Multiple Organ Failure in 11 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Multiple Organ Failure: A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine if the infusion of up to 1000 mL of diaspirin cross-linked hemoglobin (DCLHb) during the initial hospital resuscitation could reduce 28-day mortality in traumatic hemorrhagic shock patients." | 9.09 | Diaspirin cross-linked hemoglobin (DCLHb) in the treatment of severe traumatic hemorrhagic shock: a randomized controlled efficacy trial. ( Cipolle, M; Gens, D; Koenigsberg, M; Mallory, MN; Rodman, G; Runge, J; Sloan, EP, 1999) |
| "To determine if the infusion of up to 1000 mL of diaspirin cross-linked hemoglobin (DCLHb) during the initial hospital resuscitation could reduce 28-day mortality in traumatic hemorrhagic shock patients." | 5.09 | Diaspirin cross-linked hemoglobin (DCLHb) in the treatment of severe traumatic hemorrhagic shock: a randomized controlled efficacy trial. ( Cipolle, M; Gens, D; Koenigsberg, M; Mallory, MN; Rodman, G; Runge, J; Sloan, EP, 1999) |
| "Features included fever, leukocytosis with increased band forms, hypotension with a reduced SVR and multiple system organ failure (ARDS, encephalopathy, renal failure, and DIC)." | 1.28 | Fever, hyperdynamic shock, and multiple-system organ failure. A pseudo-sepsis syndrome associated with chronic salicylate intoxication. ( Leatherman, JW; Schmitz, PG, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kerner, T | 1 |
| Ahlers, O | 1 |
| Veit, S | 1 |
| Riou, B | 1 |
| Saunders, M | 1 |
| Pison, U | 1 |
| Camporota, L | 1 |
| Wyncoll, D | 1 |
| Montgomery, H | 1 |
| Porter, JC | 1 |
| Bradley, RD | 1 |
| Vadas, P | 1 |
| Schouten, BD | 1 |
| Stefanski, E | 1 |
| Scott, K | 1 |
| Pruzanski, W | 1 |
| Sakon, M | 1 |
| Kambayashi, J | 1 |
| Schultz, SC | 1 |
| Powell, CC | 1 |
| Bernard, E | 1 |
| Malcolm, DS | 1 |
| Bray, PF | 1 |
| Sloan, EP | 1 |
| Koenigsberg, M | 1 |
| Gens, D | 1 |
| Cipolle, M | 1 |
| Runge, J | 1 |
| Mallory, MN | 1 |
| Rodman, G | 1 |
| Chan, L | 1 |
| Chinnock, B | 1 |
| Matuschak, GM | 1 |
| Leatherman, JW | 1 |
| Schmitz, PG | 1 |
2 reviews available for aspirin and Multiple Organ Failure
| Article | Year |
|---|---|
Practical aspects of treatment with drotrecogin alfa (activated).
Topics: Adult; Aged; Anti-Infective Agents; APACHE; Aspirin; Child; Clinical Trials as Topic; Cost-Benefit A | 2007 |
[Treatment of multiple organ failure].
Topics: Alprostadil; Animals; Antithrombin III; Aspirin; Blood Component Transfusion; Disease Models, Animal | 1993 |
2 trials available for aspirin and Multiple Organ Failure
| Article | Year |
|---|---|
DCL-Hb for trauma patients with severe hemorrhagic shock: the European "On-Scene" multicenter study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Substitutes; European Union; Female; Flui | 2003 |
Diaspirin cross-linked hemoglobin (DCLHb) in the treatment of severe traumatic hemorrhagic shock: a randomized controlled efficacy trial.
Topics: Adult; Aspirin; Blood Substitutes; Female; Fluid Therapy; Hemoglobins; Humans; Logistic Models; Male | 1999 |
7 other studies available for aspirin and Multiple Organ Failure
| Article | Year |
|---|---|
Salicylate intoxication causing a severe systemic inflammatory response and rhabdomyolysis.
Topics: Aspirin; Female; Humans; Inflammation; Middle Aged; Multiple Organ Failure; Rhabdomyolysis | 1994 |
Association of hyperphospholipasemia A2 with multiple system organ dysfunction due to salicylate intoxication.
Topics: Aged; Aged, 80 and over; Aspirin; Female; Humans; Interleukin-6; Multiple Organ Failure; Phospholipa | 1993 |
Diaspirin crosslinked hemoglobin (DCLHb) attenuates bacterial translocation in rats.
Topics: Animals; Aspirin; Bacteria; Biological Transport; Blood Substitutes; Depression, Chemical; Hemoglobi | 1995 |
Are we still abusing aspirin?
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Multiple Organ Failure; Plate | 1998 |
Clinicopathological conference: multisystem failure in a child.
Topics: Anti-Bacterial Agents; Aspirin; Child; Clindamycin; Female; Humans; Immunoglobulins, Intravenous; Mu | 2000 |
Pseudosepsis syndrome, multiple-system organ failure, and chronic salicylate intoxication. Inhibition of regulatory eicosanoids?
Topics: Aspirin; Chronic Disease; Eicosanoids; Humans; Multiple Organ Failure; Sepsis; Syndrome | 1991 |
Fever, hyperdynamic shock, and multiple-system organ failure. A pseudo-sepsis syndrome associated with chronic salicylate intoxication.
Topics: Adult; Aged; Aspirin; Enzyme-Linked Immunosorbent Assay; Female; Fever; Hemodynamics; Humans; Hypote | 1991 |