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aspirin and Mucopolysaccharidosis III

aspirin has been researched along with Mucopolysaccharidosis III in 1 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Mucopolysaccharidosis III: Mucopolysaccharidosis characterized by heparitin sulfate in the urine, progressive mental retardation, mild dwarfism, and other skeletal disorders. There are four clinically indistinguishable but biochemically distinct forms, each due to a deficiency of a different enzyme.

Research Excerpts

ExcerptRelevanceReference
"Aspirin treatment led to the normalization of inflammation- and oxidative stress-related mRNA levels in treated MPS IIIA mouse brains."1.37Neuroinflammatory and oxidative stress phenomena in MPS IIIA mouse model: the positive effect of long-term aspirin treatment. ( Arfi, A; Bonnefont-Rousselot, D; Gandolphe, C; Richard, M; Scherman, D; Thérond, P, 2011)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arfi, A1
Richard, M1
Gandolphe, C1
Bonnefont-Rousselot, D1
Thérond, P1
Scherman, D1

Other Studies

1 other study available for aspirin and Mucopolysaccharidosis III

ArticleYear
Neuroinflammatory and oxidative stress phenomena in MPS IIIA mouse model: the positive effect of long-term aspirin treatment.
    Molecular genetics and metabolism, 2011, Volume: 103, Issue:1

    Topics: Animals; Apoptosis; Aspirin; Brain; Disease Models, Animal; Female; Gene Expression Profiling; Gene

2011