Page last updated: 2024-10-23

aspirin and Mouth Neoplasms

aspirin has been researched along with Mouth Neoplasms in 16 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Mouth Neoplasms: Tumors or cancer of the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"Oral squamous cell carcinoma (OSCC) remains one of the most challenging clinical problems in the field due to its high rate of locoregional and distant metastases."1.62Low-dose aspirin confers a survival benefit in patients with pathological advanced-stage oral squamous cell carcinoma. ( Chen, CH; Chen, WC; Chiu, TJ; Fang, FM; Hsiao, CC; Huang, TL; Li, SH; Luo, SD; Wu, CN; Wu, SC; Yang, YH, 2021)
"Inflammation is closely related to neoplastic development and the release of inflammatory cytokines and chemokines represents a crucial event in this relationship."1.51Nonsteroidal Anti-inflammatory Drugs Modulate Gene Expression of Inflammatory Mediators in Oral Squamous Cell Carcinoma. ( Antunes, DM; Corrêa, L; DE Oliveira, APL; Duarte, CME; Fernandes, KPS; Guimarães, DM; Miguita, L; Nunes, FD; Rodrigues, MFSD, 2019)
"Oral squamous cell carcinoma (OSCC) is one of the most common cancers worldwide."1.48Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma. ( Feng, H; Guo, J; Li, M; Li, Z; Zhang, X, 2018)
"Oral squamous cell carcinoma (OSCC) is a major health problem worldwide, and patients have a particularly poor 5-year survival rate."1.36Pro-inflammatory genes as biomarkers and therapeutic targets in oral squamous cell carcinoma. ( Du, Z; Fan, M; Gu, W; Jiao, Y; Kim, JG; Nosrat, CA; Pavicevic, Z; Pfeffer, LM; Rao, SK; Rosebush, M; Samant, S, 2010)
"Acute in-stent thrombosis is a well-known complication of carotid angioplasty and stenting (CAS) and often due to resistance to or inadequate treatment with platelet-inhibiting agents."1.33Late in-stent thrombosis following carotid angioplasty and stenting. ( Buhk, JH; Knauth, M; Wellmer, A, 2006)
"Aspirin use was associated with a 25% reduction in the risk of head and neck cancer (adjusted odds ratio, 0."1.33Chemoprevention of head and neck cancer with aspirin: a case-control study. ( Jayaprakash, V; Loree, TR; Menezes, RJ; Moysich, KB; Nasca, MA; Reid, ME; Rigual, NR, 2006)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's0 (0.00)18.2507
2000's6 (37.50)29.6817
2010's5 (31.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Luo, SD1
Wu, SC1
Chen, WC1
Wu, CN1
Chiu, TJ1
Yang, YH1
Li, SH1
Fang, FM1
Huang, TL1
Hsiao, CC1
Chen, CH1
Xiao, TT1
Li, X1
Feng, JL1
Li, Y1
Zhang, X1
Feng, H1
Li, Z1
Guo, J1
Li, M1
Antunes, DM1
Rodrigues, MFSD1
Guimarães, DM1
Duarte, CME1
Miguita, L1
Corrêa, L1
DE Oliveira, APL1
Fernandes, KPS1
Nunes, FD1
Park, IS1
Jo, JR1
Hong, H1
Nam, KY1
Kim, JB1
Hwang, SH1
Choi, MS1
Ryu, NH1
Jang, HJ1
Lee, SH1
Kim, CS1
Kwon, TG1
Park, GY1
Park, JW1
Jang, BC1
Rao, SK1
Pavicevic, Z1
Du, Z1
Kim, JG1
Fan, M1
Jiao, Y1
Rosebush, M1
Samant, S1
Gu, W1
Pfeffer, LM1
Nosrat, CA1
Ho, CC1
Yang, XW1
Lee, TL1
Liao, PH1
Yang, SH1
Tsai, CH1
Chou, MY1
Yang, CY1
Meng, CL1
Liao, CL1
Wong, PY1
Hölzle, F1
Kesting, MR1
Nolte, D1
Loeffelbein, DJ1
Swaid, S1
Wolff, KD1
Buhk, JH1
Wellmer, A1
Knauth, M1
Jayaprakash, V1
Rigual, NR1
Moysich, KB1
Loree, TR1
Nasca, MA1
Menezes, RJ1
Reid, ME1
Topakian, R1
Nussbaumer, K1
Trenkler, J1
Aichner, FT1
Perkins, TM1
Shklar, G1
Jolly, M1
Held, AJ1
Delaire, J1
Le Roux, JC1

Reviews

2 reviews available for aspirin and Mouth Neoplasms

ArticleYear
White lesions of the mouth.
    International journal of dermatology, 1977, Volume: 16, Issue:9

    Topics: Aspirin; Burns, Chemical; Candidiasis, Oral; Carcinoma, Squamous Cell; Cheek; Humans; Keratosis; Leu

1977
[II. Surgery of the masticatory apparatus (findings selected from the 1977-1978 literature)].
    Schweizerische Monatsschrift fur Zahnheilkunde = Revue mensuelle suisse d'odonto-stomatologie, 1978, Volume: 88, Issue:9

    Topics: Acetaminophen; Anti-Bacterial Agents; Aspirin; Bone Transplantation; Cryosurgery; Cuspid; Cysts; Dex

1978

Other Studies

14 other studies available for aspirin and Mouth Neoplasms

ArticleYear
Low-dose aspirin confers a survival benefit in patients with pathological advanced-stage oral squamous cell carcinoma.
    Scientific reports, 2021, 08-25, Volume: 11, Issue:1

    Topics: Aspirin; Carcinoma, Squamous Cell; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Mouth

2021
Combined effects of aspirin and vitamin D3 on two OSCC cell lines: a preliminary study.
    Biotechnology letters, 2018, Volume: 40, Issue:3

    Topics: Apoptosis; Aspirin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cholecalciferol;

2018
Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma.
    International journal of molecular sciences, 2018, Jul-12, Volume: 19, Issue:7

    Topics: Apoptosis; Aspirin; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movemen

2018
Nonsteroidal Anti-inflammatory Drugs Modulate Gene Expression of Inflammatory Mediators in Oral Squamous Cell Carcinoma.
    Anticancer research, 2019, Volume: 39, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Squamous Cell; Celecoxib; Cell Line, Tu

2019
Aspirin induces apoptosis in YD-8 human oral squamous carcinoma cells through activation of caspases, down-regulation of Mcl-1, and inactivation of ERK-1/2 and AKT.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blotting, Western; Carcinoma, Squamous

2010
Pro-inflammatory genes as biomarkers and therapeutic targets in oral squamous cell carcinoma.
    The Journal of biological chemistry, 2010, Oct-15, Volume: 285, Issue:42

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Biomarkers; Boronic Acids;

2010
Activation of p53 signalling in acetylsalicylic acid-induced apoptosis in OC2 human oral cancer cells.
    European journal of clinical investigation, 2003, Volume: 33, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Cycle; Cell Division; Cyclooxygena

2003
Regulation of cell growth by selective COX-2 inhibitors in oral carcinoma cell lines.
    Prostaglandins & other lipid mediators, 2003, Volume: 72, Issue:3-4

    Topics: Aspirin; Cell Division; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhib

2003
Reversible ischaemia after raising a radial forearm flap with ulceration of three fingers in a cigarette smoker.
    The British journal of oral & maxillofacial surgery, 2006, Volume: 44, Issue:1

    Topics: Anticoagulants; Aspirin; Carcinoma, Squamous Cell; Fascia; Fibrinolytic Agents; Fingers; Forearm; He

2006
Late in-stent thrombosis following carotid angioplasty and stenting.
    Neurology, 2006, May-23, Volume: 66, Issue:10

    Topics: Aged; Aged, 80 and over; Angiography, Digital Subtraction; Angioplasty, Balloon; Anticoagulants; Aph

2006
Chemoprevention of head and neck cancer with aspirin: a case-control study.
    Archives of otolaryngology--head & neck surgery, 2006, Volume: 132, Issue:11

    Topics: Alcohol Drinking; Aspirin; Case-Control Studies; Confidence Intervals; Female; Head and Neck Neoplas

2006
Late in-stent thrombosis following carotid angioplasty and stenting.
    Neurology, 2007, Jan-30, Volume: 68, Issue:5

    Topics: Aged; Aged, 80 and over; Angiography, Digital Subtraction; Angioplasty, Balloon; Anticoagulants; Aph

2007
Delay in hamster buccal pouch carcinogenesis by aspirin and indomethacin.
    Oral surgery, oral medicine, and oral pathology, 1982, Volume: 53, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Aspirin; Carcinoma, Squamous Cell;

1982
[Use of lysine acetyl-salicylate in dentistry and maxillofacial surgery].
    Science & recherche odontostomatologiques, 1971, Issue:10

    Topics: Aspirin; Dentistry; Lysine; Maxillofacial Injuries; Mouth Neoplasms; Tooth Extraction

1971