Page last updated: 2024-10-23

aspirin and Migraine with Aura

aspirin has been researched along with Migraine with Aura in 5 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Migraine with Aura: A subtype of migraine disorder, characterized by recurrent attacks of reversible neurological symptoms (aura) that precede or accompany the headache. Aura may include a combination of sensory disturbances, such as blurred VISION; HALLUCINATIONS; VERTIGO; NUMBNESS; and difficulty in concentrating and speaking. Aura is usually followed by features of the COMMON MIGRAINE, such as PHOTOPHOBIA; PHONOPHOBIA; and NAUSEA. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"The combination of clopidogrel for four weeks and aspirin for six months is superior to aspirin alone for six months for preventing migraine with aura after transcatheter closure of an atrial shunt."7.73Clopidogrel reduces migraine with aura after transcatheter closure of persistent foramen ovale and atrial septal defects. ( Morrison, WL; Nightingale, S; Walsh, KP; Wilmshurst, PT, 2005)
"The combination of clopidogrel for four weeks and aspirin for six months is superior to aspirin alone for six months for preventing migraine with aura after transcatheter closure of an atrial shunt."3.73Clopidogrel reduces migraine with aura after transcatheter closure of persistent foramen ovale and atrial septal defects. ( Morrison, WL; Nightingale, S; Walsh, KP; Wilmshurst, PT, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khardenavis, V1
Karthik, DK1
Kulkarni, S1
Deshpande, A1
Castellini, P1
Lambru, G1
Manzoni, GC1
Torelli, P1
Kurth, T1
Diener, HC1
Buring, JE1
Wilmshurst, PT1
Nightingale, S1
Walsh, KP1
Morrison, WL1
Morelli, N1
Mancuso, M1
Gori, S1
Maluccio, MR1
Cafforio, G1
Chiti, A1
Orlandi, G1
Ceretti, E1
Tartaglione, A1
Murri, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Women's Health Study of Low-dose Aspirin and Vitamin E in Apparently Healthy Women[NCT00000479]Phase 339,876 participants (Actual)Interventional1992-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Cancer, Excluding Nonmelanoma Skin Cancer

(NCT00000479)
Timeframe: Average follow-up 10.1 years

,,,
Interventionparticipants (Number)
Total invasive cancerCancer death
Aspirin + Vitamin E716152
Aspirin Only722132
Both Placebos706143
Vitamin E Only721156

Number of Participants With Major Cardiovascular Events (a Combined Endpoint of Nonfatal Myocardial Infarction, Nonfatal Stroke, and Total Cardiovascular Death)

(NCT00000479)
Timeframe: Average follow-up 10.1 years

,,,
InterventionParticipants (Number)
Major cardiovascular eventStrokeMyocardial infarctionCardiovascular death
Aspirin + Vitamin E23210810254
Aspirin Only2451139666
Both Placebos2721339974
Vitamin E Only2501339452

Trials

1 trial available for aspirin and Migraine with Aura

ArticleYear
Migraine and cardiovascular disease in women and the role of aspirin: subgroup analyses in the Women's Health Study.
    Cephalalgia : an international journal of headache, 2011, Volume: 31, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Female; Humans; Middle Ag

2011

Other Studies

4 other studies available for aspirin and Migraine with Aura

ArticleYear
Cortical laminar necrosis in a case of migrainous cerebral infarction.
    BMJ case reports, 2018, Mar-28, Volume: 2018

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Cerebral Cortex; Cerebral

2018
Atrial septal defect closure and migraine with aura: is there a correlation?
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2009, Volume: 30, Issue:4

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Cardiac Surgical Procedu

2009
Clopidogrel reduces migraine with aura after transcatheter closure of persistent foramen ovale and atrial septal defects.
    Heart (British Cardiac Society), 2005, Volume: 91, Issue:9

    Topics: Adult; Aspirin; Cardiac Catheterization; Clopidogrel; Drug Therapy, Combination; Female; Heart Septa

2005
Vertebral artery dissection onset mimics migraine with aura in a graphic designer.
    Headache, 2008, Volume: 48, Issue:4

    Topics: Anticoagulants; Aspirin; Diagnosis, Differential; Heparin; Humans; Magnetic Resonance Angiography; M

2008