Page last updated: 2024-10-23

aspirin and Migraine Disorders

aspirin has been researched along with Migraine Disorders in 247 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"Adding clopidogrel to aspirin for 3 months after transcatheter atrial septal defect (ASD) closure results in a lower incidence of new-onset migraine attacks."9.41Effect of Clopidogrel and Aspirin vs Aspirin Alone on Migraine Headaches After Transcatheter Atrial Septal Defect Closure: One-Year Results of the CANOA Randomized Clinical Trial. ( Cheema, AN; Côté, M; Horlick, E; Houde, C; Ibrahim, R; Labinaz, M; Marrero, A; Marsal, JR; Nadeem, N; Osten, M; Rivest, D; Rodés-Cabau, J; Wintzer-Wehekind, J, 2021)
"For more than a century, aspirin has been used for the acute treatment of primary headaches."8.90Pharmacokinetics and safety of a new aspirin formulation for the acute treatment of primary headaches. ( D'Alonzo, L; Lecchi, M; Martelletti, P; Negro, A, 2014)
"(1) To establish whether pre-treatment headache intensity in migraine or episodic tension-type headache (ETTH) predicts success or failure of treatment with aspirin; and (2) to reflect, accordingly, on the place of aspirin in the management of these disorders."7.78Aspirin is first-line treatment for migraine and episodic tension-type headache regardless of headache intensity. ( Lampl, C; Steiner, TJ; Voelker, M, 2012)
"We report an asthmatic adolescent female who had anaphylaxis with 650 mg acetaminophen after tolerating 325-mg doses for years."7.69Acetaminophen anaphylaxis with aspirin and sodium salicylate sensitivity: a case report. ( Ham Pong, A; Schwarz, N, 1996)
"Cranial allodynia associated with spontaneous migraine is reported as either responsive to triptan treatment or to be predictive of lack of triptan efficacy."6.90Nitroglycerine triggers triptan-responsive cranial allodynia and trigeminal neuronal hypersensitivity. ( Akerman, S; Bose, P; Goadsby, PJ; Hoffmann, JR; Holland, PR; Karsan, N; Romero-Reyes, M, 2019)
"The occurrence of new-onset migraine attacks is a complication of transcatheter atrial septal defect (ASD) closure."6.80Effect of Clopidogrel and Aspirin vs Aspirin Alone on Migraine Headaches After Transcatheter Atrial Septal Defect Closure: The CANOA Randomized Clinical Trial. ( Cheema, AN; Côté, M; Horlick, E; Houde, C; Ibrahim, R; Labinaz, M; Marrero, A; Marsal, JR; Nadeem, N; Osten, M; Rivest, D; Rodés-Cabau, J, 2015)
" Additional studies are needed to assess the relationship between caffeine dosing and clinical benefits in patients with TTH and migraine."6.55Caffeine in the management of patients with headache. ( Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS, 2017)
"Adding clopidogrel to aspirin for 3 months after transcatheter atrial septal defect (ASD) closure results in a lower incidence of new-onset migraine attacks."5.41Effect of Clopidogrel and Aspirin vs Aspirin Alone on Migraine Headaches After Transcatheter Atrial Septal Defect Closure: One-Year Results of the CANOA Randomized Clinical Trial. ( Cheema, AN; Côté, M; Horlick, E; Houde, C; Ibrahim, R; Labinaz, M; Marrero, A; Marsal, JR; Nadeem, N; Osten, M; Rivest, D; Rodés-Cabau, J; Wintzer-Wehekind, J, 2021)
"The results of this subgroup analysis confirm that the fixed combination of ASA (250 mg), paracetamol (200 mg), and caffeine (50 mg) is effective and well tolerated in a broad spectrum from mild to severe migraine and tension-type headache severity independently of the headache diagnosis."5.15The efficacy and tolerability of a fixed combination of acetylsalicylic acid, paracetamol, and caffeine in patients with severe headache: a post-hoc subgroup analysis from a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel g ( Aicher, B; Diener, HC; Peil, H, 2011)
" In a randomized double-blind study including individuals with either migraine or tension-type headache (TTH) we showed significant superiority of the fixed combination of acetylsalicylic acid + paracetamol + caffeine over the combination without caffeine, the single preparations, and placebo in the treatment of headache."5.14Headache classification by history has only limited predictive value for headache episodes treated in controlled trials with OTC analgesics. ( Aicher, B; Diener, HC; Lipton, RB; Pageler, L; Peil, H; Pfaffenrath, V, 2009)
"We investigated efficacy, safety, and tolerability of two tablets of the fixed combination of 250 mg acetylsalicylic acid (ASA) + 200 mg paracetamol + 50 mg caffeine (Thomapyrin) in comparison with two tablets of 250 mg ASA + 200 mg paracetamol, two tablets of 500 mg ASA, two tablets of 500 mg paracetamol, two tablets of 50 mg caffeine, and placebo in patients who were used to treating their episodic tension-type headache or migraine attacks with non-prescription analgesics."5.11The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group st ( Aicher, B; Diener, HC; Pageler, L; Peil, H; Pfaffenrath, V, 2005)
" In this review, we discuss the possible repurposing of drugs approved for cardiovascular diseases, such as β-blockers, angiotensin converting enzyme inhibitors (ACE-Is), angiotensin II receptor blockers (ARBs), statins, aspirin, cardiac glycosides and low-molecular-weight heparins (LMWHs)."5.05Repurposing of drugs approved for cardiovascular diseases: Opportunity or mirage? ( Camera, M; Castiglioni, L; Gelosa, P; Sironi, L, 2020)
" For hemicrania we used cinnarizine, cyproheptadine, clonidine, histamine, pizotifene and reserpine; for cluster headache, cinnarizine, cyproheptadine, clonidine, histamine and reserpine; for tension headache, cyproheptadine; for psychogenic headache, allylpropylmalonylurea."5.04[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)]. ( Agostoni, A; Brandi, G; Cottino, A; Gai, V; Gastaldi, L; Lisino, F; Nattero, G, 1975)
"For more than a century, aspirin has been used for the acute treatment of primary headaches."4.90Pharmacokinetics and safety of a new aspirin formulation for the acute treatment of primary headaches. ( D'Alonzo, L; Lecchi, M; Martelletti, P; Negro, A, 2014)
" Addition of metoclopramide 10 mg improves relief of nausea and vomiting."4.89Aspirin with or without an antiemetic for acute migraine headaches in adults. ( Derry, S; Kirthi, V; Moore, RA, 2013)
" Addition of metoclopramide 10 mg improves relief of nausea and vomiting."4.86Aspirin with or without an antiemetic for acute migraine headaches in adults. ( Derry, S; Kirthi, V; McQuay, HJ; Moore, RA, 2010)
" I have selected 4 translations in the field of vascular neurology in which I have been involved in different respects: (1) the translation of results from men to women, taking the example of aspirin which, in primary prevention, decreases the risk of myocardial infarction in men and the risk of cerebral infarction in women, the reason for this sex difference being so far unknown; (2) the 'inverse translational research', from bedside to bench, taking the example of the disease we have identified--CADASIL--and showing how the study of one patient and his family led to the identification of a gene, Notch3, so far unknown in humans and to the discovery of its key role in the physiology of vascular smooth muscle cells; (3) the translation from individual case reports to multidisciplinary trials taking the example of hemicraniectomy in malignant cerebral infarction and emphasizing the interest in such rare and severe conditions of pooling and reporting the results of randomized clinical trials before the results of individual trials, and (4) the translation from research to practice, emphasizing not the well-known 'evidence to practice gap' but the slippery slope of 'lack of evidence to overpractice', taking the example of patent foramen ovale closure in migraine."4.84Some translations in vascular neurology. The Johann Jacob Wepfer Award 2008. ( Bousser, MG, 2008)
"Using a single group, pretest/posttest design, 50 migraineurs without prior history of stroke or MI were prospectively treated for 14 to 21 consecutive days with 325 mg generic enteric-coated aspirin, after undergoing a 14-day aspirin washout."3.78Aspirin's effect on platelet inhibition in migraineurs. ( Fuller, CJ; Jesurum, JT; Lucas, SM; Murinova, N; Truva, CM, 2012)
"(1) To establish whether pre-treatment headache intensity in migraine or episodic tension-type headache (ETTH) predicts success or failure of treatment with aspirin; and (2) to reflect, accordingly, on the place of aspirin in the management of these disorders."3.78Aspirin is first-line treatment for migraine and episodic tension-type headache regardless of headache intensity. ( Lampl, C; Steiner, TJ; Voelker, M, 2012)
" However, long-term use of NSAIDs is associated with side-effects, mainly involving the gastrointestinal tract."3.77[Migraine and non-steroidal anti-inflammatory agents]. ( Pradalier, A; Vincent, D, 1992)
"We report an asthmatic adolescent female who had anaphylaxis with 650 mg acetaminophen after tolerating 325-mg doses for years."3.69Acetaminophen anaphylaxis with aspirin and sodium salicylate sensitivity: a case report. ( Ham Pong, A; Schwarz, N, 1996)
"Cranial allodynia associated with spontaneous migraine is reported as either responsive to triptan treatment or to be predictive of lack of triptan efficacy."2.90Nitroglycerine triggers triptan-responsive cranial allodynia and trigeminal neuronal hypersensitivity. ( Akerman, S; Bose, P; Goadsby, PJ; Hoffmann, JR; Holland, PR; Karsan, N; Romero-Reyes, M, 2019)
"Many migraine patients rely on over-the-counter analgesics for the treatment of migraine attacks."2.82Aspirin, paracetamol (acetaminophen) and caffeine for the treatment of acute migraine attacks: A systemic review and meta-analysis of randomized placebo-controlled trials. ( Diener, HC; Gaul, C; Lehmacher, W; Weiser, T, 2022)
"The occurrence of new-onset migraine attacks is a complication of transcatheter atrial septal defect (ASD) closure."2.80Effect of Clopidogrel and Aspirin vs Aspirin Alone on Migraine Headaches After Transcatheter Atrial Septal Defect Closure: The CANOA Randomized Clinical Trial. ( Cheema, AN; Côté, M; Horlick, E; Houde, C; Ibrahim, R; Labinaz, M; Marrero, A; Marsal, JR; Nadeem, N; Osten, M; Rivest, D; Rodés-Cabau, J, 2015)
"In patients with severe baseline migraine pain, AAC and IB are significantly more effective than PLA, and AAC provides significantly faster and more effective pain relief than IB."2.79Results of a multicenter, double-blind, randomized, parallel-group, placebo-controlled, single-dose study comparing the fixed combination of acetaminophen, acetylsalicylic acid, and caffeine with ibuprofen for acute treatment of patients with severe migra ( Gold, M; Goldstein, J; Hagen, M, 2014)
"Provoking delayed migraine with nitroglycerin in migraine sufferers is a cumbersome model."2.75Nitroglycerin provocation in normal subjects is not a useful human migraine model? ( Iversen, HK; Olesen, J; Tfelt-Hansen, P; Tvedskov, JF, 2010)
"A total of 1555 migraineurs were included in the analysis."2.72Acetaminophen, aspirin, and caffeine in combination versus ibuprofen for acute migraine: results from a multicenter, double-blind, randomized, parallel-group, single-dose, placebo-controlled study. ( Goldstein, J; Lipton, RB; Ryan, RE; Saper, JR; Silberstein, SD, 2006)
"In 20 healthy subjects without migraine and in 20 healthy subjects with migraine without aura, platelet and erythrocyte aggregation were measured before and after intake of placebo, acetylsalicylic acid, ergotamine tartrate, zolmitriptan and sumatriptan."2.72The impact of different antimigraine compounds on platelet and erythrocyte aggregation. ( Akova-Oztürk, E; Evers, S; Frese, A; Heuel, T; Husstedt, IW, 2006)
"Aspirin was significantly more effective than placebo for pain reduction beginning 1 hour after dosing (P<."2.71Aspirin is efficacious for the treatment of acute migraine. ( Baggish, JS; Goldstein, J; Lipton, RB; Quiring, JN; Sorrentino, JV; Yataco, AR, 2005)
"Acute migraine attacks are often associated with gastrointestinal symptoms ranging from mild nausea to vomiting."2.71[Comparison of the effectiveness of lysine acetylsalicylate and metoclopramide combination with ergotamine plus caffeine in the treatment of migraine attacks]. ( Kozubski, W; Stepień, A, 2004)
"Eighteen patients suffering from migraine without aura were analysed."2.71Effects of symptomatic treatments on cutaneous hyperalgesia and laser evoked potentials during migraine attack. ( de Tommaso, M; Di Fruscolo, O; Guido, M; Lamberti, P; Libro, G; Livrea, P; Losito, L; Sardaro, M; Sciruicchio, V, 2005)
"1620 patients with migraine, meeting International Headache Society (IHS) criteria were included in the study."2.71[Assessment of efficacy of migraine attack treatment with lysine acetylsalicylate and metoclopramide]. ( Kozubski, W; Stepień, A, 2004)
"Both drugs were effective in acute migraine attacks with a trend in favor of iLAS."2.71Comparison of intravenous valproate with intravenous lysine-acetylsalicylic acid in acute migraine attacks. ( Diener, HC; Leniger, T; Limmroth, V; Pageler, L; Stude, P, 2005)
"Most people who experience migraine use OTC medications to treat their symptoms, but no head-to-head clinical trials comparing these agents with prescription migraine therapies have been published."2.71Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial. ( Baggish, J; Battikha, JP; Elkind, AH; Gallagher, RM; Goldstein, J; Hoffman, H; Saper, JR; Silberstein, SD; Smith, TR, 2005)
"Eletriptan was well-tolerated; 6 (3."2.71Eletriptan treatment of migraine in patients switching from barbiturate-containing analgesics: results from a multiple-attack study. ( Almas, M; Hilliard, B; Loder, E; Martin, VT; Taylor, K, 2005)
"One hundred one patients diagnosed with migraine (according to the International Headache Society diagnostic criteria) participated in the study."2.70Mouth-dispersible aspirin in the treatment of migraine: a placebo-controlled study. ( Davies, PT; Dowson, A; MacGregor, EA, 2002)
"Seventeen patients with unilateral migraine headache were studied within 6 hours of onset."2.70Acute migraine headache: possible sensitization of neurons in the spinal trigeminal nucleus? ( Diener, HC; Drepper, J; Ellrich, J; Katsarava, Z; Kaube, H; Przywara, S, 2002)
"Although migraine is more common among women than men, the only two large, randomized trials of low-dose aspirin for migraine prophylaxis have been conducted in men."2.70Low-dose aspirin for migraine prophylaxis in women. ( Benseñor, IM; Buring, JE; Chown, MJ; Cook, NR; Hennekens, CH; Lee, IM, 2001)
" The global incidence of adverse events was 45% higher with EC, though not significant (32 vs."2.69Comparative efficacy and safety of calcium carbasalate plus metoclopramide versus ergotamine tartrate plus caffeine in the treatment of acute migraine attacks. ( Geraud, G; Gómez, JP; Henry, P; Joffroy, A; Lainez, JM; Le Jeunne, C; Liaño, H; Pradalier, A; Titus i Albareda, F, 1999)
"in 56 patients (112 attacks) with acute migraine."2.69Lysine-acetylsalicylic acid in acute migraine attacks. ( Diener, H; Limmroth, V; May, A, 1999)
"For both menstruation-associated migraine and migraine not associated with menses, the proportion of subjects with pain intensity reduced to mild or none (responders) was significantly greater with AAC than with placebo at all postdose time points from 0."2.69Treatment of menstruation-associated migraine with the nonprescription combination of acetaminophen, aspirin, and caffeine: results from three randomized, placebo-controlled studies. ( Armellino, JJ; Battikha, JP; Hamelsky, SW; Hoffman, HD; Lipton, RB; Silberstein, SD; Stewart, WF, 1999)
" Sumatriptan is more effective, but resulted in more adverse events."2.69Efficacy and safety of intravenous acetylsalicylic acid lysinate compared to subcutaneous sumatriptan and parenteral placebo in the acute treatment of migraine. A double-blind, double-dummy, randomized, multicenter, parallel group study. The ASASUMAMIG St ( Diener, HC, 1999)
" Five hundred thirty-five adverse effects were reported after the use of 22,697 sachets."2.69Safety and efficacy of combined lysine acetylsalicylate and metoclopramide: repeated intakes in migraine attacks. ( Baudesson, G; Chabriat, H; Danchot, J; Joire, JE; Pradalier, A, 1999)
"The most severely disabled segment of migraineurs, including those whose attacks usually required bed rest, or who vomited 20% or more of the time, were excluded."2.69Efficacy and safety of acetaminophen, aspirin, and caffeine in alleviating migraine headache pain: three double-blind, randomized, placebo-controlled trials. ( Lipton, RB; Ryan, RE; Saper, J; Sheftell, F; Silberstein, S; Stewart, WF, 1998)
"Physicians reporting migraine (n = 1479) had significantly increased risks of subsequent total stroke and ischemic stroke compared with those not reporting migraine."2.68Migraine and subsequent risk of stroke in the Physicians' Health Study. ( Buring, JE; Cook, N; Hebert, P; Hennekens, C; Kittross, A; Manson, J; Peto, R; Romero, J, 1995)
"Aspirin is commonly used to treat migraine attacks, although sumatriptan, a much more expensive treatment, is also effective."2.68The effectiveness of combined oral lysine acetylsalicylate and metoclopramide compared with oral sumatriptan for migraine. ( Chazot, G; Henry, P; Mulder, LJ; Scheldewaert, RG; Schoenen, J; Tfelt-Hansen, P, 1995)
"If the brain of migraineurs is characterized between attacks by a reduction of mitochondrial phosphorylation potential, riboflavin, which has the potential of increasing mitochondrial energy efficiency, might have prophylactic effects in migraine."2.67High-dose riboflavin as a prophylactic treatment of migraine: results of an open pilot study. ( Bastings, E; Lenaerts, M; Schoenen, J, 1994)
"The patients had to treat two migraine attacks with LAS-MCP (1620 mg lysine acetylsalicylate--the equivalent of 900 mg aspirin--combined with 10 mg metoclopramide) or placebo."2.67Combined oral lysine acetylsalicylate and metoclopramide in the acute treatment of migraine: a multicentre double-blind placebo-controlled study. ( Bousser, MG; Chabriat, H; Danchot, J; Grippon, P; Joire, JE, 1994)
"These data indicate that migraine is mediated, at least in part, by the effects of platelets and suggest that low-dose aspirin should be considered for prophylaxis among those with a history of established migraine."2.67Low-dose aspirin for migraine prophylaxis. ( Buring, JE; Hennekens, CH; Peto, R, 1990)
"In the treatment of acute migraine and the prevention of recurrent attacks, there are prescription drugs of proven benefit."2.66Aspirin in the Treatment and Prevention of Migraine Headaches: Possible Additional Clinical Options for Primary Healthcare Providers. ( Biglione, B; Gitin, A; Gorelick, PB; Hennekens, C, 2020)
"Although migraine improves or disappears during pregnancy, a significant association between migraine and hypertension (i."2.66The Potential Protective Role of Aspirin Against Migraine in Pregnant Women. ( Gong, Y; Liu, X, 2020)
" Medication was given as one dosage in the evening: 2-5 mg/kg KG ASS or 5-10 mg Flunarizine."2.66[Prevention of migraine with flunarizine and acetylsalicylic acid. A double-blind study]. ( Pothmann, R, 1987)
"Aspirin was significantly better than placebo for pain but not quite significant for nausea."2.65Effervescent metoclopramide and aspirin (Migravess) versus effervescent aspirin or placebo for migraine attacks: a double-blind study. ( Olesen, J; Tfelt-Hansen, P, 1984)
"All drug classes were found to favour migraine chronification."2.58Is Medication Overuse Drug Specific or Not? Data from a Review of Published Literature and from an Original Study on Italian MOH Patients. ( D'Amico, D; Grazzi, L; Grignani, E; Raggi, A; Sansone, E, 2018)
"The use of melatonin for migraine showed that (i) reduced the number of days with pain and the analgesic consumption when compared with placebo, (ii) no benefits on headache intensity, number of headache days and analgesics consumption when compared with amitriptyline, (iii) reduced the number of analgesic consumption, the attack frequency and the headache intensity when associated with propranolol plus nortriptyline vs placebo plus propranolol plus nortriptyline, and (iv) no difference for any of the interest outcomes when associated with propranolol plus nortriptyline vs sodium valproate plus propranolol plus nortriptyline."2.58Melatonin for preventing primary headache: A systematic review. ( Adriano Leal Freitas da Costa, A; de Oliveira Cruz Latorraca, C; Leite Pacheco, R; Luiza Cabrera Martimbianco, A; Riera, R; Vianna Pachito, D, 2018)
" Additional studies are needed to assess the relationship between caffeine dosing and clinical benefits in patients with TTH and migraine."2.55Caffeine in the management of patients with headache. ( Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS, 2017)
" Safety was evaluated based on the frequency of reported adverse events, and treatment with eASA was associated with lower incidence of adverse events than was with sumatriptan."2.44Efficacy and safety of 1,000 mg effervescent aspirin: individual patient data meta-analysis of three trials in migraine headache and migraine accompanying symptoms. ( Diener, HC; Lampl, C; Voelker, M, 2007)
"The treatment of migraine takes into consideration the intensity of the headache and the accompanying symptoms."2.42[Treatment and prophylaxis of an acute migraine attack]. ( Diener, HC; Gendolla, A, 2004)
"Migraine is a typical "women's disease": the fluctuations of sex hormones, in particular estrogens, during woman's reproductive life show a direct and major influence on migraine course."2.42[Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies]. ( Airola, G; Allais, G; Benedetto, C; Bosio, A; Ciochetto, D; De Lorenzo, C; Mana, O; Quirico, PE; Terzi, MG, 2003)
"The acute treatment and prophylaxis of migraine headache are discussed in this article."2.41[The problems of migraine headache treatment]. ( Vaitkus, A; Vilionskis, A, 2002)
"In comparison with transient ischemic attacks in patients with vascular risk factors, the usual neurologic presentation of ET consists of brief attacks of sudden cerebral or visual dysfunction, which can be either well localized or diffuse and entirely nonspecific."2.40Neurologic and visual symptoms in essential thrombocythemia: efficacy of low-dose aspirin. ( Koudstaal, A; Koudstaal, PJ, 1997)
"Management of migraine patients with or without aura must include appropriate medication to treat the attack and long-term preventive therapy, especially if the frequency of the attacks is greater than 2-4 per month."2.40Medical treatment of migraine: from mechanisms of action to contraindications. ( Annoni, JM; Higelin, F, 1998)
"The occurrence of migraine in women is influenced by hormonal changes throughout the lifecycle."2.40Migraine in pregnancy: what are the safest treatment options? ( Pfaffenrath, V; Rehm, M, 1998)
"The various forms of ASA used to treat headache are discussed and the controlled studies conducted to evaluate ASA's efficacy in headache treatment are summarized."2.40Acetylsalicylic acid in the treatment of headache. ( Diener, HC; Katsarava, Z; Limmroth, V, 1999)
"Efficacy of acute OTC medications for migraine varies greatly."1.91Predictors of treatment-response to caffeine combination products, acetaminophen, acetylsalicylic acid (aspirin), and nonsteroidal anti-inflammatory drugs in acute treatment of episodic migraine. ( Ezzati, A; Fanning, KM; Lipton, RB; Reed, ML, 2023)
"Prochlorperazine injection has been upgraded to a highly recommended level because of the rich clinical experience for this treatment."1.722022 Taiwan Guidelines for Acute Treatment of Migraine. ( Lau, CI; Wang, YF, 2022)
"Incident breast cancer cases were confirmed by medical record review."1.39Migraine and subsequent risk of breast cancer: a prospective cohort study. ( Buring, JE; Kurth, T; Lee, IM; Rexrode, KM; Tamimi, RM; Winter, AC, 2013)
"Glucose metabolic changes in CM patients taking different dosage of analgesic during headache-free periods and clear distinctions in several brain regions were observed."1.39Overuse of paracetamol caffeine aspirin powders affects cerebral glucose metabolism in chronic migraine patients. ( Di, W; Fang, Y; Luo, N; Miao, J; Qi, W; Shi, X; Tao, Y; Xiao, Z; Yi, C; Zhang, A; Zhang, X; Zhu, Y, 2013)
"This study identified underdiagnosis of migraine, low use of migraine prophylaxis and triptans, and high prevalence of medication overuse among subjects seeking self-medication for regular headache."1.38[Self-medication of regular headache: a community pharmacy-based survey in Belgium]. ( Boussery, K; Christiaens, T; De Bolle, L; Evrard, B; Mehuys, E; Paemeleire, K; Philippe, G; Piette, M; Prévôt, ML; Remon, JP; Van Bortel, L; Van Hees, T; Van Tongelen, I, 2012)
"In some cases, the clinical features of migraine-associated vertigo may mimic the presentation of Menière's disease."1.36Case reports on two patients with episodic vertigo, fluctuating hearing loss and migraine responding to prophylactic drugs for migraine. Menière's disease or migraine-associated vertigo? ( Bussi, M; Fabiano, B; Limardo, P; Recanati, P; Teggi, R, 2010)
"These findings were compatible with systemic lupus erythematosus (SLE)."1.36[Sporadic hemiplegic migraine-like headache in a patient with systemic lupus erythematosus]. ( Doi, H; Isobe, N; Kira, J; Ohyagi, Y; Tateishi, T; Yamasaki, R, 2010)
"Treatment patterns in migraine patients with cardiovascular risk factors are largely unknown."1.35Treatment choices and patterns in migraine patients with and without a cardiovascular risk profile. ( Egberts, AC; Tijssen, CC; Wammes-van der Heijden, EA, 2009)
"Oral triptans outperform oral ergotamine most because of the extremely low (< 1%) oral bioavailability of ergotamine."1.35[Triptans versus other migraine medicine--secondary publication]. ( Tfelt-Hansen, P, 2009)
"Migraine and migraine aura status were self-reported."1.35Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease. ( Buring, JE; Kurth, T; Schürks, M; Zee, RY, 2008)
"The IHS criteria (1988) for migraine were identified correctly by 92."1.34[Acetylsalicylic acid in self-medication of migraine. A pharmacy-based observational study]. ( Gessner, U; Göbel, H; Petersen-Braun, M; Weingärtner, U, 2007)
"We present a case of transient global amnesia after cardiac catheterization associated with migraine headache and MRI changes compatible with an ischemic insult."1.33Magnetic resonance imaging changes in a patient with migraine attack and transient global amnesia after cardiac catheterization. ( Elkind, MS; Fernandez, A; Mazer, SP; Rincon, F, 2005)
"The sequence and timing of taking migraine medications, whether prescription or over-the-counter, and the patient's response to their treatment, is unknown."1.33Acute migraine treatment: patterns of use and satisfaction in a clinical population. ( Hopkins, M; Malik, SN; Silberstein, SD; Young, WB, 2006)
"= 1, F = 25."1.32Abnormal habituation of 'nociceptive' blink reflex in migraine--evidence for increased excitability of trigeminal nociception. ( Diener, HC; Giffin, N; Katsarava, Z; Kaube, H, 2003)
"The effects of classical and new anti-migraine drugs such as acetylsalicylic acid (ASA), sumatriptan and the new high efficacy 5-HT1B/1D agonist donitriptan (4-[4-[2-(2-aminoethyl)-1H-indol-5-yloxyl]acetyl]piperazinyl-1-yl]benzonitrile) were evaluated in comparison with the established model of neurogenic inflammation in the meninges."1.31An in vivo rat model to study calcitonin gene related peptide release following activation of the trigeminal vascular system. ( Diener, HC; Guehring, H; Katsarava, Z; Liedert, B; Limmroth, V; Michel, MC; Schmitz, K, 2001)
"All patients using an abortive migraine drug (ergotamine or sumatriptan) and subsequently treated with either coumarin (index group) or low-dose acetylsalicylic acid (control group) were analyzed."1.31Reduction in the intensity of abortive migraine drug use during coumarin therapy. ( Buurma, H; Egberts, AC; Leufkens, HG; Rahimtoola, H; Tijssen, CC, 2001)
"A diagnosis of hemiplegic migraine was made."1.31[Hemiplegic migraine. A series of 5 patients]. ( Capodieci, C; Guala, A; Licardi, G; Peretti, M, 2000)
" Therefore, it is quite possible that both drugs produce adverse immunological effects in vivo in cases of high dosage or obstruction of elimination."1.31[Effect of migraine medications on monocyte chemotaxis] . ( Krumholz, W; Menges, T; Ogal, H; Szalay, G, 2000)
"Preliminary results from 12 migraine patients indicated that 9 of 12 (75%) had significant benefit from this approach."1.31Hypothesized treatment for migraines using low doses of tryptophan, niacin, calcium, caffeine, and acetylsalicylic acid. ( Gedye, A, 2001)
"91 patients with migraine were examined in terms of quantitative evaluation of the severity of the attacks."1.30[Differentiated therapy of migraine attack]. ( Amelin, AV; Korenko, LA; Skoromets, AA, 1999)
"We report five cases in which anorectal stenosis was associated with chronic administration of suppositories containing paracetamol and acetylsalicylic acid."1.29Anorectal stenosis in patients with prolonged use of suppositories containing paracetamol and acetylsalicylic acid. ( Adler, M; Cremer, M; Houben, JJ; Peny, MO; Van Gossum, A; Zalcman, M, 1993)
"Although classical migraine is known to produce lateralized sensory disturbances (e."1.29Visual field effects of classical migraine. ( Boles, DB, 1993)
"In patients with migraine, ECT may be expected to trigger a migraine attack, probably in the same way as spontaneous seizures."1.29Migraine after electroconvulsive therapy. ( Folkerts, H, 1995)
"psychogenic dissociation is considered."1.28Organic dissociative syndrome associated with antimigraine pharmacotherapy. ( Good, MI, 1991)
"Improvement of migraine index was not related to different plasma levels of the two drugs."1.27Propranolol and acetylsalicylic acid in migraine prophylaxis. Double-blind crossover study. ( Baldrati, A; Baruzzi, A; Cortelli, P; D'Alessandro, R; Gamberini, G; Procaccianti, G; Sacquegna, T, 1983)
"The main treatment of the acute migraine attack remains sleep, sedation, an anti-nauseant and analgesics, and in some patients 1 or 2 mg of ergotamine tartrate."1.27Treatment of the acute migraine attack--current status. ( Wilkinson, M, 1983)
"The different effect of ASA in TIAs and migraine indicates that the platelet activation in TIA patients is due not only to cyclo-oxygenase pathway but also to other in vivo pathways."1.27Drugs and platelet activation in migraine and transient ischemic attacks. ( Canazi, A; D'Andrea, G; Ferro-Milone, F; Toldo, M, 1985)
"However, the presence of a migraine aura appeared to improve the chances of a response to aspirin."1.26Aspirin treatment of migraine attacks: clinical observations. ( Eadie, MJ; Ross-Lee, L; Tyrer, JH, 1982)
"In an acute migraine clinic, patients were all treated with metoclopramide 10 mg i."1.26Paracetamol (acetaminophen) versus acetylsalicylic acid in migraine. ( Olesen, J; Tfelt-Hansen, P, 1980)
"In acute migraine the combination of dextropropoxyphene, a centrally acting analgesic, with acetylsalicylic acid and phenazone gives an alternative to ergotamine tartrate that is equally effective and causes less nausea and vomiting."1.26Mild analgesics as an alternative to ergotamine in migraine. A comparative trial with acetylsalicylic acid, ergotamine tartrate, and a dextropropoxyphene compound. ( Hakkarainen, H; Quiding, H; Stockman, O, 1980)
"A case where common and complicated migraine attacks appeared during the course of oral contraception is reported."1.26Migraine attacks and increased platelet aggregability induced by oral contraceptives. ( Mazal, S, 1978)
"Patients having one or more attacks of migraine a week may need prophylactic treatment."1.26[The use of drugs in migraine]. ( Wilkinson, M, 1976)
"26 untreated migraineurs and 19 migraineurs with history of self-medication with aspirin taken within 72 hours of the test, were studied in headache-free intervals."1.26Platelet dysfunction in migraine: effect of self-medication with aspirin. ( Deshmukh, SV; Meyer, JS; Mouche, RJ, 1976)
" Patients given aspirin with oral metoclopramide tended to obtain better early pain relief than the other two treatment groups, though by one hour from dosage use of injected metoclopramide was also associated with better pain relief."1.26Aspirin treatment of migraine attacks: plasma drug level data. ( Eadie, MJ; Heazlewood, V; Ross-Lee, L; Tyrer, JH, 1982)

Research

Studies (247)

TimeframeStudies, this research(%)All Research%
pre-199086 (34.82)18.7374
1990's51 (20.65)18.2507
2000's69 (27.94)29.6817
2010's32 (12.96)24.3611
2020's9 (3.64)2.80

Authors

AuthorsStudies
Diener, HC20
Gaul, C2
Lehmacher, W1
Weiser, T1
Lau, CI1
Wang, YF1
Ezzati, A1
Fanning, KM1
Reed, ML1
Lipton, RB8
Biglione, B1
Gitin, A1
Gorelick, PB1
Hennekens, C2
Alpert, JS1
Gelosa, P1
Castiglioni, L1
Camera, M1
Sironi, L1
Liu, X1
Gong, Y1
Wintzer-Wehekind, J1
Horlick, E2
Ibrahim, R2
Cheema, AN2
Labinaz, M2
Nadeem, N2
Osten, M2
Côté, M2
Marsal, JR2
Rivest, D2
Marrero, A2
Houde, C2
Rodés-Cabau, J2
Schofield, JR1
Hughes, HN1
Birlea, M1
Hassell, KL1
Robbins, MS1
Garas, SY1
Patel, K1
Diener, H-1
Leite Pacheco, R1
de Oliveira Cruz Latorraca, C1
Adriano Leal Freitas da Costa, A1
Luiza Cabrera Martimbianco, A1
Vianna Pachito, D1
Riera, R1
Grazzi, L1
Grignani, E1
D'Amico, D1
Sansone, E1
Raggi, A1
Akerman, S1
Karsan, N1
Bose, P1
Hoffmann, JR1
Holland, PR1
Romero-Reyes, M1
Goadsby, PJ2
D'Arrigo, S1
Tessarollo, V1
Maselli, E1
Pantaleoni, C1
Canafoglia, L1
Kirthi, V3
Derry, S3
Moore, RA3
Saguil, A1
Herness, J1
Ingledue, VF1
Mounsey, A1
Krome, S1
Goldstein, J5
Hagen, M1
Gold, M1
Lecchi, M1
D'Alonzo, L1
Negro, A1
Martelletti, P1
Huynh, K1
Schürks, M1
Zee, RY1
Buring, JE5
Kurth, T2
Bousser, MG4
Hofmann, R1
Pfaffenrath, V4
Pageler, L3
Peil, H3
Aicher, B3
Sarens, T1
Herroelen, L1
Van Deyk, K1
Budts, W1
Wammes-van der Heijden, EA1
Tijssen, CC2
Egberts, AC2
Tfelt-Hansen, P7
Tvedskov, JF1
Iversen, HK1
Olesen, J4
McQuay, HJ1
Doi, H1
Tateishi, T1
Isobe, N1
Yamasaki, R1
Ohyagi, Y1
Kira, J1
Keller, DL1
Goodyear-Smith, F1
Bhindi, R1
Ormerod, OJ1
Teggi, R1
Fabiano, B1
Recanati, P1
Limardo, P1
Bussi, M1
Lampl, C3
Voelker, M5
Steiner, TJ1
Wainscott, G1
Kaspi, T1
Volans, GN3
Bertschi, M1
Sturzenegger, M1
Hess, CW1
Jesurum, JT1
Fuller, CJ1
Murinova, N1
Truva, CM1
Lucas, SM1
McQuay, H1
Mehuys, E1
Paemeleire, K1
Van Hees, T1
Christiaens, T1
Van Bortel, L1
Van Tongelen, I1
Philippe, G1
Prévôt, ML1
Evrard, B1
Piette, M1
De Bolle, L1
Remon, JP1
Boussery, K1
Di, W1
Shi, X1
Zhu, Y1
Tao, Y1
Qi, W1
Luo, N1
Xiao, Z1
Yi, C1
Miao, J1
Zhang, A1
Zhang, X1
Fang, Y1
Froehler, MT1
Winter, AC1
Rexrode, KM1
Lee, IM2
Tamimi, RM1
Cantisani, TA1
Celani, MG1
Hankey, GJ1
Sandercock, PA1
Gupta, R1
Gupta, S1
Wyderski, RJ1
Limmroth, V5
Vilionskis, A1
Vaitkus, A1
Burk, CT1
Gilderman, A1
Salas, J1
Berenbeim, D1
Nichol, MB1
DOSAL, AF1
DEL PINAL, JL1
SENNE, W1
TASEI, LA1
ROY, JC1
MASURE, A1
SAVINEL, E1
DEHAENE, P1
LEBEURRE, P1
DESSINGES, S1
MONCKTON, G1
Katsarava, Z4
Giffin, N1
Kaube, H3
Gaciong, Z1
Bruegel, C1
Landzberg, MJ1
Khairy, P1
Grübler, B1
Allais, G1
Bosio, A1
Mana, O1
Airola, G1
Ciochetto, D1
Terzi, MG1
De Lorenzo, C1
Quirico, PE1
Benedetto, C1
Eikermann, A3
Gessner, U2
Göbel, H3
Haag, G2
Lange, R3
May, A2
Müller-Schwefe, G1
Croissant, B1
Brosi, K1
Hermann, D1
Mann, K1
Stepień, A2
Kozubski, W3
Bussone, G2
de Liano, H1
Englert, R1
Floeter, T1
Gallai, V1
Hartung, E2
Jimenez, MD1
Manzoni, GC1
Mueller-Schwefe, G1
Nappi, G1
Pinessi, L1
Prat, J1
Puca, FM1
Titus, F1
Gendolla, A1
Pradalier, A3
Chabriat, H2
Danchot, J2
Baudesson, G1
Joire, JE2
Leniger, T1
Stude, P1
Dalmose, AL1
Baggish, JS1
Yataco, AR1
Sorrentino, JV1
Quiring, JN1
de Tommaso, M1
Losito, L1
Libro, G1
Guido, M1
Di Fruscolo, O1
Sardaro, M1
Sciruicchio, V1
Lamberti, P1
Livrea, P1
Martin, VT1
Loder, E1
Taylor, K1
Almas, M1
Hilliard, B1
Silberstein, SD4
Saper, JR2
Elkind, AH1
Smith, TR1
Gallagher, RM1
Battikha, JP3
Hoffman, H1
Baggish, J1
Fernandez, A1
Rincon, F1
Mazer, SP1
Elkind, MS1
Blumenthal, HJ1
Diamond, ML1
Wenzel, RG1
Ryan, RE6
Reimnitz, P1
Malik, SN1
Hopkins, M1
Young, WB1
Evers, S2
Heuel, T1
Frese, A1
Akova-Oztürk, E1
Husstedt, IW2
Petersen-Braun, M1
Weingärtner, U1
Scholbach, T1
Shin, JI1
Lee, JS1
Ducros, A1
Derosier, FJ1
Kori, SH1
Jindeel, A1
Parantainen, J2
Hakkarainen, H4
Vapaatalo, H2
Gothoni, G2
Ziegler, A1
Boiardi, A1
Crenna, P1
Merati, B1
Negri, S1
Tansini, E1
D'Andrea, G2
Cananzi, A1
Toldo, M2
Cortelazzo, S1
Ferro-Milone, F2
Wilkinson, M6
Smith, M1
Jerusalem, F1
Rhyner, K1
Isler, H1
Peters, KS1
Blau, JN1
Baldrati, A1
Cortelli, P1
Procaccianti, G1
Gamberini, G1
D'Alessandro, R1
Baruzzi, A1
Sacquegna, T1
Ross-Lee, LM1
Eadie, MJ4
Heazlewood, V2
Bochner, F1
Tyrer, JH3
Masel, BE1
Chesson, AL1
Peters, BH1
Levin, HS1
Alperin, JB1
Lewis, RH1
Ross-Lee, L2
Wind, J2
Punt, J2
Tomlin, P1
Newton, R1
Prendes, JL1
Rochel, M1
Dieterich, E1
Diamond, S1
Medina, JL1
Quiding, H1
Stockman, O2
Henry, P4
Mulder, LJ2
Scheldewaert, RG2
Schoenen, J4
Chazot, G2
Vein, A1
Voznesenskaya, T1
Danilov, A1
Lenaerts, M1
Bastings, E1
Hebert, P1
Romero, J1
Kittross, A1
Cook, N1
Manson, J1
Peto, R3
Hiesse-Provost, O1
Dillenschneider, A1
Ganry, H1
Insuasty, J1
Grippon, P1
Anaya Ordóñez, S1
Matas Hoces, A1
Boureau, F1
Joubert, JM1
Lasserre, V1
Prum, B1
Delecoeuillerie, G1
Hoffman, LM1
Van Gossum, A1
Zalcman, M1
Adler, M1
Peny, MO1
Houben, JJ1
Cremer, M1
Boles, DB1
Trojani, FT1
Catheline, JM1
Guiberteau/Canfrere, V1
Zarka, O1
Le Borgne, J1
Lehur, PA1
Folkerts, H1
Graf, WD1
Riback, PS1
Wiedemann, M1
de Lima, VM1
Hanke, W1
Nelson-Piercy, C1
De Swiet, M1
Michiels, JJ1
van Genderen, PJ1
Jansen, PH1
Koudstaal, PJ2
Schwarz, N1
Ham Pong, A1
Koudstaal, A1
Strong, FC1
Stewart, WF2
Saper, J1
Silberstein, S1
Sheftell, F1
Higelin, F1
Annoni, JM1
Danilov, AB1
Chernyshov, OIu1
Veĭn, AM1
Kolosova, OA2
Rehm, M1
Maizels, M1
Le Jeunne, C1
Gómez, JP1
Titus i Albareda, F1
Joffroy, A1
Liaño, H1
Lainez, JM1
Geraud, G2
Diener, H1
Rhodes, KF1
Buckingham, JC1
Kennard, C1
Armellino, JJ2
Hoffman, HD2
Hamelsky, SW2
Puri, V1
Riggs, G1
Couch, J1
Blumenthal, H1
Skoromets, AA1
Amelin, AV1
Korenko, LA1
Vergne, P1
Bertin, P1
Trèves, R1
Noth, J1
Capodieci, C1
Guala, A1
Licardi, G1
Peretti, M1
Schwarz, JA1
Hohn, M1
Krumholz, W1
Szalay, G1
Ogal, H1
Menges, T1
Gedye, A1
McGinnis, J1
Seaton, TL1
Evans, RW1
Liedert, B1
Guehring, H1
Schmitz, K1
Michel, MC1
Wright, CA1
Tefferi, A1
Wiedemann, B1
Chrubasik, J1
Latta, G1
Hauke, W1
Benseñor, IM1
Cook, NR1
Chown, MJ1
Hennekens, CH2
Rahimtoola, H1
Buurma, H1
Leufkens, HG1
Compagnon, A1
Rossi, A1
Przywara, S1
Drepper, J1
Ellrich, J1
MacGregor, EA1
Dowson, A1
Davies, PT1
Dulou, R1
Hauret, L1
Renard, JL1
Valle, JN1
Béquet, D1
Felten, D1
Glover, V1
Sandler, M1
Grant, E1
Rose, FC1
Orton, D1
Stevens, D1
Bone, I1
Durward, WF1
Hind, VM1
O'Neill, BP1
Mann, JD1
Fozard, JR1
Mazal, S1
Gustafsson, B1
Grobe, T1
Krabbe, AA1
Veilis, B1
Hicks, M1
Dalessio, DJ5
Otis, S1
Smith, R1
Critchley, EM1
Malmgren, R1
Olsson, P1
Tornling, G1
Unge, G1
Sjaastad, O1
Dale, I1
Nattero, G1
Agostoni, A1
Brandi, G1
Cottino, A1
Gai, V1
Gastaldi, L1
Lisino, F1
Deshmukh, SV1
Meyer, JS1
Mouche, RJ1
Parkes, JD1
Callaghan, N1
Bodis, J1
Tinneberg, HR1
Vincent, D1
Good, MI1
Frick, G1
Frick, U1
Frost, E1
Brachmann, K1
Grotemeyer, KH1
Scharafinski, HW1
Schlake, HP1
Burke, M1
Kudrow, DB1
Kudrow, L1
Massiou, H1
Richter, R1
Holmsen, H1
Canazi, A1
Chick, J1
Fuseau, E1
Soisson, T1
Thevenet, R1
Siemes, H1
Casaer, P1
Pothmann, R1
Britton, BH1
Block, LD1
Brandon, RA1
Curran, AC1
Nolan, PC1
Presneill, JJ1
Patterson, MC1
Hosman-Benjaminse, SL1
Bolhuis, PA1
Pöllmann, W1
Kimura, S1
Niguma, T1
Nagaro, T1
Arai, T1
Rasmussen, BK1
Dexter, SL1
Graham, AN1
Johnston, ES1
Ratcliffe, DM1
Wilkinson, MI2
Rose, AJ1
Waldenlind, E1
Ross, SB1
Sääf, J1
Ekbom, K1
Wetterberg, L1
Girard, D1
Noda, S1
Itoh, H1
Umezaki, H1
Fukuda, Y1
Frisén, L1
Friedman, AP1
Barrie, MA1
Fox, WR1
Weatherall, M1
Kok-Jensen, A1
Lindeneg, O1
Olafsson, O1
Gudmundsson, KR1
Brekkan, A1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clopidogrel On Top of Aspirin For the Prevention of New Onset Migraine Headache Occurrence Following Transcatheter Closure of Atrial Septal Defects: A Prospective Randomized Trial (the CANOA Study)[NCT00799045]Phase 4220 participants (Actual)Interventional2008-10-31Completed
Acute Headache Treatment in Pregnancy: Improvement in Pain Scores With Occipital Nerve Block vs PO Acetaminophen With Caffeine A Randomized Controlled Trial[NCT03951649]Phase 462 participants (Actual)Interventional2020-02-10Completed
Acute Mountain Sickness Treatment: A Double-blind Comparison of Metoclopramide vs. Ibuprofen[NCT01522326]300 participants (Anticipated)Interventional2012-03-01Completed
Potential Effects of Virtual Reality Technology on the Treatment of Migraine-Type Headaches: Randomized Observational Study[NCT06061588]100 participants (Anticipated)Interventional2023-10-31Not yet recruiting
Effects of Myofascial Trigger Points Therapy in Migraine.[NCT05646160]100 participants (Anticipated)Interventional2018-01-15Recruiting
[NCT00000500]Phase 30 participants Interventional1981-09-30Completed
Women's Health Study of Low-dose Aspirin and Vitamin E in Apparently Healthy Women[NCT00000479]Phase 339,876 participants (Actual)Interventional1992-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of Headache Free Period at 7 Days

(NCT03951649)
Timeframe: 7 days

Interventiondays (Median)
Occipital Nerve Block6
Oral Acetaminophen/Caffeine Group1

Number of Participants With Development of Hypertensive Disease of Pregnancy Within 28 Days

(NCT03951649)
Timeframe: 28 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block9
Oral Acetaminophen/Caffeine Group4

Number of Participants With Development of Hypertensive Disease of Pregnancy Within 7 Days

(NCT03951649)
Timeframe: 7 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block7
Oral Acetaminophen/Caffeine Group2

Number of Participants With Injection Site Complication (Infection, Hematoma, and Ecchymosis)

Other: Pain at injection site (NCT03951649)
Timeframe: 7 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block0
Oral Acetaminophen/Caffeine Group2

Number of Participants With Need for Admission for Treatment of Headache

(NCT03951649)
Timeframe: 7 hours

InterventionParticipants (Count of Participants)
Occipital Nerve Block0
Oral Acetaminophen/Caffeine Group0

Number of Participants With Need for Crossover Treatment

(NCT03951649)
Timeframe: 4 hours

InterventionParticipants (Count of Participants)
Occipital Nerve Block9
Oral Acetaminophen/Caffeine Group14

Number of Participants With Need for Neurology Consult

(NCT03951649)
Timeframe: 5 hours

InterventionParticipants (Count of Participants)
Occipital Nerve Block4
Oral Acetaminophen/Caffeine Group2

Number of Participants With Need for Representation for Treatment of Headache With 28 Days

Emergency department for treatment of headache since treatment asked at 28 day follow up (NCT03951649)
Timeframe: 28 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block5
Oral Acetaminophen/Caffeine Group1

Number of Participants With Need for Second Line Treatment

(NCT03951649)
Timeframe: 120 min

InterventionParticipants (Count of Participants)
Occipital Nerve Block5
Oral Acetaminophen/Caffeine Group5

Number of Participants With Response to Occipital Nerve Block in Pregnancy

Based on guidelines from the International Headache Society the primary outcome is the portion of women who experience resolution of headache or improvement of headache to mild range (VRS ≤ 3) at 2 hours following treatment with Occipital nerve block as compared to acetaminophen/caffeine cocktail. (NCT03951649)
Timeframe: 60-300 min

InterventionParticipants (Count of Participants)
Occipital Nerve Block20
Oral Acetaminophen/Caffeine Group16

Response to Cross Over Treatment at 60 Min

"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 60 min

Interventionscore on a scale (Median)
Occipital Nerve Block6
Oral Acetaminophen/Caffeine Group3

Response to Second Line Treatment at 60 Min

"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 180min

Interventionscore on a scale (Median)
Occipital Nerve Block6
Oral Acetaminophen/Caffeine Group4

Response to Treatment Within 2 Hours

"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 2 hrs

Interventionscore on a scale (Median)
Occipital Nerve Block6.0
Oral Acetaminophen/Caffeine Group6.5

Number of Participants With Cancer, Excluding Nonmelanoma Skin Cancer

(NCT00000479)
Timeframe: Average follow-up 10.1 years

,,,
Interventionparticipants (Number)
Total invasive cancerCancer death
Aspirin + Vitamin E716152
Aspirin Only722132
Both Placebos706143
Vitamin E Only721156

Number of Participants With Major Cardiovascular Events (a Combined Endpoint of Nonfatal Myocardial Infarction, Nonfatal Stroke, and Total Cardiovascular Death)

(NCT00000479)
Timeframe: Average follow-up 10.1 years

,,,
InterventionParticipants (Number)
Major cardiovascular eventStrokeMyocardial infarctionCardiovascular death
Aspirin + Vitamin E23210810254
Aspirin Only2451139666
Both Placebos2721339974
Vitamin E Only2501339452

Reviews

37 reviews available for aspirin and Migraine Disorders

ArticleYear
Aspirin, paracetamol (acetaminophen) and caffeine for the treatment of acute migraine attacks: A systemic review and meta-analysis of randomized placebo-controlled trials.
    European journal of neurology, 2022, Volume: 29, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Humans; Migraine Disorders; Randomized C

2022
Aspirin in the Treatment and Prevention of Migraine Headaches: Possible Additional Clinical Options for Primary Healthcare Providers.
    The American journal of medicine, 2020, Volume: 133, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Drug Administrat

2020
Repurposing of drugs approved for cardiovascular diseases: Opportunity or mirage?
    Biochemical pharmacology, 2020, Volume: 177

    Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Conv

2020
The Potential Protective Role of Aspirin Against Migraine in Pregnant Women.
    Medical science monitor : international medical journal of experimental and clinical research, 2020, Aug-02, Volume: 26

    Topics: Aspirin; Drug Administration Schedule; Drug Dosage Calculations; Endothelium, Vascular; Female; Huma

2020
Caffeine in the management of patients with headache.
    The journal of headache and pain, 2017, Oct-24, Volume: 18, Issue:1

    Topics: Abdominal Pain; Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Central Nervous System Stimulan

2017
    MMW Fortschritte der Medizin, 2017, Volume: 159, Issue:18

    Topics: Analgesics; Aspirin; Diclofenac; Humans; Ibuprofen; Migraine Disorders; Pyrrolidines; Randomized Con

2017
Melatonin for preventing primary headache: A systematic review.
    International journal of clinical practice, 2018, Volume: 72, Issue:7

    Topics: Acetaminophen; Analgesics; Aspirin; Central Nervous System Depressants; Humans; Melatonin; Migraine

2018
Is Medication Overuse Drug Specific or Not? Data from a Review of Published Literature and from an Original Study on Italian MOH Patients.
    Current pain and headache reports, 2018, Aug-27, Volume: 22, Issue:11

    Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspiri

2018
Aspirin with or without an antiemetic for acute migraine headaches in adults.
    The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Drug Therapy, Combination; Hum

2013
Pharmacokinetics and safety of a new aspirin formulation for the acute treatment of primary headaches.
    Expert opinion on drug metabolism & toxicology, 2014, Volume: 10, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Headache; Humans

2014
Some translations in vascular neurology. The Johann Jacob Wepfer Award 2008.
    Cerebrovascular diseases (Basel, Switzerland), 2008, Volume: 26, Issue:3

    Topics: Aspirin; Awards and Prizes; Biomedical Research; CADASIL; Cardiovascular Agents; Cardiovascular Dise

2008
Aspirin with or without an antiemetic for acute migraine headaches in adults.
    The Cochrane database of systematic reviews, 2010, Apr-14, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Drug Therapy, Combination; Hum

2010
Aspirin for acute migraine headaches in adults.
    Journal of neurology, neurosurgery, and psychiatry, 2013, Volume: 84, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Dopamine Antagonists; Drug Therapy, C

2013
Analgesics.
    Current medical research and opinion, 2001, Volume: 17 Suppl 1

    Topics: Acetaminophen; Administration, Intranasal; Administration, Oral; Analgesics, Non-Narcotic; Analgesic

2001
[The problems of migraine headache treatment].
    Medicina (Kaunas, Lithuania), 2002, Volume: 38, Issue:7

    Topics: Aged; Analgesics; Analgesics, Non-Narcotic; Aspirin; Dihydroergotamine; Female; Humans; Male; Methys

2002
The real dimension of analgesic activity of aspirin.
    Thrombosis research, 2003, Jun-15, Volume: 110, Issue:5-6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Comorbidity; Dose-Respon

2003
Staying a step ahead of migraines.
    Nursing, 2003, Volume: 33, Issue:11

    Topics: Acupuncture Therapy; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Contraceptives, Oral, Hormona

2003
Indications for the closure of patent foramen ovale.
    Heart (British Cardiac Society), 2004, Volume: 90, Issue:2

    Topics: Anticoagulants; Aspirin; Balloon Occlusion; Decision Making; Decompression Sickness; Heart Septal De

2004
[Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies].
    Minerva medica, 2003, Volume: 94, Issue:4 Suppl 1

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Acupuncture Points; Acupuncture Therapy; Adult; Analgesi

2003
[Treatment and prophylaxis of an acute migraine attack].
    MMW Fortschritte der Medizin, 2004, Sep-02, Volume: 146, Issue:35-36

    Topics: Acupuncture Therapy; Acute Disease; Administration, Oral; Adrenergic beta-Antagonists; Analgesics; A

2004
Aspirin in the treatment of acute migraine attacks.
    Expert review of neurotherapeutics, 2006, Volume: 6, Issue:4

    Topics: Acute Disease; Aspirin; Humans; Migraine Disorders; Pain Measurement

2006
[Self-medication of migraine and headache].
    MMW Fortschritte der Medizin, 2006, Nov-23, Volume: 148, Issue:47

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine;

2006
Efficacy and safety of 1,000 mg effervescent aspirin: individual patient data meta-analysis of three trials in migraine headache and migraine accompanying symptoms.
    Journal of neurology, 2007, Volume: 254, Issue:6

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relatio

2007
[Acute and chronic headaches].
    La Revue du praticien, 2006, Dec-15, Volume: 56, Issue:19

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir

2006
Pharmacologic treatment of recurrent pediatric headache.
    Pediatric annals, 1995, Volume: 24, Issue:9

    Topics: Acetaminophen; Adolescent; Adrenal Cortex Hormones; Analgesics; Aspirin; Child; Child, Preschool; Er

1995
Atypical transient ischemic attacks in thrombocythemia of various myeloproliferative disorders.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Adult; Aged; Aspirin; Capillaries; Cerebral Arteries; Diagnosis, Differential; Erythromelalgia; Fema

1996
Neurologic and visual symptoms in essential thrombocythemia: efficacy of low-dose aspirin.
    Seminars in thrombosis and hemostasis, 1997, Volume: 23, Issue:4

    Topics: Anticoagulants; Aspirin; Brain Ischemia; Diagnosis, Differential; Erythromelalgia; Headache; Humans;

1997
Medical treatment of migraine: from mechanisms of action to contraindications.
    Schweizerische medizinische Wochenschrift, 1998, Mar-07, Volume: 128, Issue:10

    Topics: Acetaminophen; Adrenergic beta-Antagonists; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Asp

1998
Migraine in pregnancy: what are the safest treatment options?
    Drug safety, 1998, Volume: 19, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Female; Humans; Migraine Disorders; Pregnancy; Pre

1998
Acetylsalicylic acid in the treatment of headache.
    Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Headache; Humans; Migraine Disorders; Treatment Ou

1999
[Aspirin, pain and inflammation].
    La Revue de medecine interne, 2000, Volume: 21 Suppl 1

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Child; Colic; Controlle

2000
The effectiveness of combined oral lysine acetylsalicylate and metoclopramide (Migpriv) in the treatment of migraine attacks. Comparison with placebo and oral sumatriptan.
    Functional neurology, 2000, Volume: 15 Suppl 3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dopamine Antagonists; Drug Combinations; Humans; L

2000
A single institutional experience with 43 pregnancies in essential thrombocythemia.
    European journal of haematology, 2001, Volume: 66, Issue:3

    Topics: Abortion, Induced; Abortion, Spontaneous; Abruptio Placentae; Adult; Anticoagulants; Aspirin; Busulf

2001
The animal pharmacology of drugs used in the treatment of migraine.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:5

    Topics: Acetaminophen; Adrenergic alpha-Antagonists; Analgesics; Animals; Aspirin; Caffeine; Clonidine; Cypr

1975
[Transient ischemia attacks in general practice].
    Die Medizinische Welt, 1979, Sep-07, Volume: 30, Issue:36

    Topics: Anticoagulants; Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Carotid Arteries; Diagnosis,

1979
[Migraine and non-steroidal anti-inflammatory agents].
    Pathologie-biologie, 1992, Volume: 40, Issue:4

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic

1992
[Pharmacotherapy of migraine--indications and experiences].
    Zeitschrift fur arztliche Fortbildung, 1988, Volume: 82, Issue:24

    Topics: Aspirin; Drug Therapy, Combination; Ergotamine; Humans; Metoclopramide; Migraine Disorders

1988

Trials

65 trials available for aspirin and Migraine Disorders

ArticleYear
Effect of Clopidogrel and Aspirin vs Aspirin Alone on Migraine Headaches After Transcatheter Atrial Septal Defect Closure: One-Year Results of the CANOA Randomized Clinical Trial.
    JAMA cardiology, 2021, 02-01, Volume: 6, Issue:2

    Topics: Adult; Aspirin; Cardiac Catheterization; Clopidogrel; Dual Anti-Platelet Therapy; Duration of Therap

2021
Nitroglycerine triggers triptan-responsive cranial allodynia and trigeminal neuronal hypersensitivity.
    Brain : a journal of neurology, 2019, 01-01, Volume: 142, Issue:1

    Topics: Adolescent; Adult; Aspirin; Double-Blind Method; Humans; Hyperalgesia; Middle Aged; Migraine Disorde

2019
Results of a multicenter, double-blind, randomized, parallel-group, placebo-controlled, single-dose study comparing the fixed combination of acetaminophen, acetylsalicylic acid, and caffeine with ibuprofen for acute treatment of patients with severe migra
    Cephalalgia : an international journal of headache, 2014, Volume: 34, Issue:13

    Topics: Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination;

2014
Effect of Clopidogrel and Aspirin vs Aspirin Alone on Migraine Headaches After Transcatheter Atrial Septal Defect Closure: The CANOA Randomized Clinical Trial.
    JAMA, 2015, Nov-24, Volume: 314, Issue:20

    Topics: Aspirin; Cardiac Catheterization; Cardiac Surgical Procedures; Clopidogrel; Double-Blind Method; Dru

2015
Headache classification by history has only limited predictive value for headache episodes treated in controlled trials with OTC analgesics.
    Cephalalgia : an international journal of headache, 2009, Volume: 29, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Caffeine; Double-Blind Me

2009
Patent foramen ovale closure and migraine: are we following the wrong pathway?
    Journal of neurology, 2009, Volume: 256, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Catheterization; Cardiac Surgical P

2009
Nitroglycerin provocation in normal subjects is not a useful human migraine model?
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:8

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Double-Blin

2010
The efficacy and tolerability of a fixed combination of acetylsalicylic acid, paracetamol, and caffeine in patients with severe headache: a post-hoc subgroup analysis from a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel g
    Cephalalgia : an international journal of headache, 2011, Volume: 31, Issue:14

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster

2011
The influence of thiethylperazine on the absorption of effervescent aspirin in migraine.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:6

    Topics: Adult; Antiemetics; Aspirin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Met

1976
Efficacy of 1,000 mg effervescent acetylsalicylic acid and sumatriptan in treating associated migraine symptoms.
    European neurology, 2004, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Aged; Aspirin; Demography; Double-Blind Method; Female; Follow-Up Studies; Humans

2004
[Comparison of the effectiveness of lysine acetylsalicylate and metoclopramide combination with ergotamine plus caffeine in the treatment of migraine attacks].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2004, Volume: 57, Issue:3-4

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Caffeine; Central Nervous System Stimulants; Dopamin

2004
Placebo-controlled comparison of effervescent acetylsalicylic acid, sumatriptan and ibuprofen in the treatment of migraine attacks.
    Cephalalgia : an international journal of headache, 2004, Volume: 24, Issue:11

    Topics: Adult; Aspirin; Chemistry, Pharmaceutical; Chi-Square Distribution; Confidence Intervals; Cross-Over

2004
Safety and efficacy of combined lysine acetylsalicylate and metoclopramide: repeated intakes in migraine attacks.
    Headache, 1999, Volume: 39, Issue:2

    Topics: Adult; Analgesics; Antiemetics; Aspirin; Dose-Response Relationship, Drug; Drug Therapy, Combination

1999
Comparison of intravenous valproate with intravenous lysine-acetylsalicylic acid in acute migraine attacks.
    Headache, 2005, Volume: 45, Issue:1

    Topics: Acute Disease; Analgesics; Aspirin; Double-Blind Method; GABA Agents; Humans; Infusions, Intravenous

2005
[Assessment of efficacy of migraine attack treatment with lysine acetylsalicylate and metoclopramide].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004, Volume: 17, Issue:102

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dopamine Antagonists; Dru

2004
Aspirin is efficacious for the treatment of acute migraine.
    Headache, 2005, Volume: 45, Issue:4

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Double-Blind Method; Humans; Migrai

2005
Effects of symptomatic treatments on cutaneous hyperalgesia and laser evoked potentials during migraine attack.
    Cephalalgia : an international journal of headache, 2005, Volume: 25, Issue:5

    Topics: Adult; Aspirin; Evoked Potentials; Female; Hot Temperature; Humans; Hyperalgesia; Indoles; Lasers; L

2005
Eletriptan treatment of migraine in patients switching from barbiturate-containing analgesics: results from a multiple-attack study.
    Cephalalgia : an international journal of headache, 2005, Volume: 25, Issue:9

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Barbiturates; Caffeine; Drug Combinations; Fe

2005
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
    Headache, 2005, Volume: 45, Issue:8

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non-

2005
The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group st
    Cephalalgia : an international journal of headache, 2005, Volume: 25, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine;

2005
Acetaminophen, aspirin, and caffeine in combination versus ibuprofen for acute migraine: results from a multicenter, double-blind, randomized, parallel-group, single-dose, placebo-controlled study.
    Headache, 2006, Volume: 46, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ca

2006
The impact of different antimigraine compounds on platelet and erythrocyte aggregation.
    Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:8

    Topics: Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studie

2006
Prostaglandin inhibitors and gastric factors in migraine.
    Lancet (London, England), 1980, Apr-12, Volume: 1, Issue:8172

    Topics: Aspirin; Clinical Trials as Topic; Double-Blind Method; Ergotamine; Gastric Emptying; Humans; Migrai

1980
Effervescent metoclopramide and aspirin (Migravess) versus effervescent aspirin or placebo for migraine attacks: a double-blind study.
    Cephalalgia : an international journal of headache, 1984, Volume: 4, Issue:2

    Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Drug Combinations; Female; Humans; Male; Metoclopram

1984
Aspirin pharmacokinetics in migraine. The effect of metoclopramide.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:6

    Topics: Adult; Aspirin; Drug Interactions; Female; Humans; Kinetics; Male; Metoclopramide; Migraine Disorder

1983
Platelet antagonists in migraine prophylaxis. A clinical trial using aspirin and dipyridamole.
    Headache, 1980, Volume: 20, Issue:1

    Topics: Adult; Aspirin; Blood Platelets; Clinical Trials as Topic; Dipyridamole; Double-Blind Method; Drug T

1980
The effectiveness of combined oral lysine acetylsalicylate and metoclopramide compared with oral sumatriptan for migraine.
    Lancet (London, England), 1995, Oct-07, Volume: 346, Issue:8980

    Topics: Administration, Oral; Adolescent; Adult; Analgesics; Aspirin; Dopamine Antagonists; Double-Blind Met

1995
The effects of aspirin on the CNV in healthy individuals.
    Cephalalgia : an international journal of headache, 1995, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Analysis of Variance; Aspirin; Contingent Negative Variation; Cross-Over Studies;

1995
High-dose riboflavin as a prophylactic treatment of migraine: results of an open pilot study.
    Cephalalgia : an international journal of headache, 1994, Volume: 14, Issue:5

    Topics: Aspirin; Brain; Drug Therapy, Combination; Energy Metabolism; Humans; Migraine Disorders; Pilot Proj

1994
Migraine and subsequent risk of stroke in the Physicians' Health Study.
    Archives of neurology, 1995, Volume: 52, Issue:2

    Topics: Adult; Aged; Aspirin; beta Carotene; Cardiovascular Diseases; Carotenoids; Cerebrovascular Disorders

1995
[Efficacy and tolerance of an effervescent aspirin-metoclopramide combination in the treatment of a migraine attack. Randomized double-blind study using a placebo].
    Presse medicale (Paris, France : 1983), 1995, Feb-04, Volume: 24, Issue:5

    Topics: Administration, Oral; Adult; Aspirin; Double-Blind Method; Drug Combinations; Family Practice; Femal

1995
Combined oral lysine acetylsalicylate and metoclopramide in the acute treatment of migraine: a multicentre double-blind placebo-controlled study.
    Cephalalgia : an international journal of headache, 1994, Volume: 14, Issue:4

    Topics: Administration, Oral; Adult; Analgesics; Aspirin; Double-Blind Method; Drug Therapy, Combination; Fe

1994
[Sumatriptan in the treatment of acute migraine: its role in primary health care].
    Atencion primaria, 1994, Apr-30, Volume: 13, Issue:7

    Topics: Acute Disease; Administration, Oral; Algorithms; Aspirin; Caffeine; Double-Blind Method; Drug Therap

1994
Double-blind comparison of an acetaminophen 400 mg-codeine 25 mg combination versus aspirin 1000 mg and placebo in acute migraine attack.
    Cephalalgia : an international journal of headache, 1994, Volume: 14, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Codeine; Double-Blind Method; Drug Therapy, Combina

1994
[The combination of oral lysine-acetylsalicylate and metoclopramide compared with oral sumatriptan in the treatment of migraine attacks. A randomized, double-blind, placebo-controlled clinical trial].
    Ugeskrift for laeger, 1996, Nov-04, Volume: 158, Issue:45

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics;

1996
It may be the caffeine in Extra Strength Excedrin that is effective for migraine.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:12

    Topics: Acetaminophen; Adjuvants, Pharmaceutic; Analgesics; Aspirin; Caffeine; Dose-Response Relationship, D

1997
Efficacy and safety of acetaminophen, aspirin, and caffeine in alleviating migraine headache pain: three double-blind, randomized, placebo-controlled trials.
    Archives of neurology, 1998, Volume: 55, Issue:2

    Topics: Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination;

1998
Comparative efficacy and safety of calcium carbasalate plus metoclopramide versus ergotamine tartrate plus caffeine in the treatment of acute migraine attacks.
    European neurology, 1999, Volume: 41, Issue:1

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Th

1999
Lysine-acetylsalicylic acid in acute migraine attacks.
    European neurology, 1999, Volume: 41, Issue:2

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Double-B

1999
Treatment of menstruation-associated migraine with the nonprescription combination of acetaminophen, aspirin, and caffeine: results from three randomized, placebo-controlled studies.
    Clinical therapeutics, 1999, Volume: 21, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammato

1999
Efficacy and safety of intravenous acetylsalicylic acid lysinate compared to subcutaneous sumatriptan and parenteral placebo in the acute treatment of migraine. A double-blind, double-dummy, randomized, multicenter, parallel group study. The ASASUMAMIG St
    Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:6

    Topics: Adult; Analgesics; Aspirin; Double-Blind Method; Female; Humans; Infusions, Intravenous; Injections,

1999
Treatment of severe, disabling migraine attacks in an over-the-counter population of migraine sufferers: results from three randomized, placebo-controlled studies of the combination of acetaminophen, aspirin, and caffeine.
    Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Caffeine; Double-Blind Method; D

1999
Acetylsalicylic acid effervescent 1000 mg (Aspirin) in acute migraine attacks; a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group study.
    Cephalalgia : an international journal of headache, 2000, Volume: 20, Issue:7

    Topics: Acute Disease; Adult; Aspirin; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Diso

2000
The effectiveness of combined oral lysine acetylsalicylate and metoclopramide (Migpriv) in the treatment of migraine attacks. Comparison with placebo and oral sumatriptan.
    Functional neurology, 2000, Volume: 15 Suppl 3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dopamine Antagonists; Drug Combinations; Humans; L

2000
A comparative study of oral acetylsalicyclic acid and metoprolol for the prophylactic treatment of migraine. A randomized, controlled, double-blind, parallel group phase III study.
    Cephalalgia : an international journal of headache, 2001, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Female; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders;

2001
Low-dose aspirin for migraine prophylaxis in women.
    Cephalalgia : an international journal of headache, 2001, Volume: 21, Issue:3

    Topics: Adult; Aspirin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combin

2001
Zolmitriptan versus a combination of acetylsalicylic acid and metoclopramide in the acute oral treatment of migraine: a double-blind, randomised, three-attack study.
    European neurology, 2002, Volume: 47, Issue:2

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aspirin; Double-Blind Method; Drug The

2002
Acute migraine headache: possible sensitization of neurons in the spinal trigeminal nucleus?
    Neurology, 2002, Apr-23, Volume: 58, Issue:8

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Blinking;

2002
Mouth-dispersible aspirin in the treatment of migraine: a placebo-controlled study.
    Headache, 2002, Volume: 42, Issue:4

    Topics: Abdominal Pain; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;

2002
Aspirin prophylaxis in migraine.
    Lancet (London, England), 1978, Dec-02, Volume: 2, Issue:8101

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Mid

1978
Tolfenamic acid is as effective as ergotamine during migraine attacks.
    Lancet (London, England), 1979, Aug-18, Volume: 2, Issue:8138

    Topics: Adolescent; Adult; Aspirin; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Consumer Behavi

1979
A comparative trail of ergotamine tartrate, acetyl salicylic acid and a dextropropoxyphene compound in acute migraine attacks.
    Headache, 1978, Volume: 18, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aspirin; Clinical Trials as Topic; Dextropropoxyphene; Ergotamine;

1978
A new (?) Clinical headache entity "chronic paroxysmal hemicrania" 2.
    Acta neurologica Scandinavica, 1976, Volume: 54, Issue:2

    Topics: Affective Symptoms; Aspirin; Cerebrovascular Circulation; Chronic Disease; Clinical Trials as Topic;

1976
The effect of metoclopramide on the absorption of effervescent aspirin in migraine.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:1

    Topics: Adult; Aspirin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gastrointestinal Motili

1975
[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1975, Sep-19, Volume: 117, Issue:38

    Topics: Aspirin; Caffeine; Cinnarizine; Clinical Trials as Topic; Clonidine; Cyproheptadine; Drug Therapy, C

1975
A study to compare oral sumatriptan with oral aspirin plus oral metoclopramide in the acute treatment of migraine. The Oral Sumatriptan and Aspirin plus Metoclopramide Comparative Study Group.
    European neurology, 1992, Volume: 32, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aspirin; Double-Blind Method; Drug Therapy, Combinati

1992
[Migraine and non-steroidal anti-inflammatory agents].
    Pathologie-biologie, 1992, Volume: 40, Issue:4

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic

1992
Low-dose aspirin for migraine prophylaxis.
    JAMA, 1990, Oct-03, Volume: 264, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Chi-Square Distribution; Double-Blind Method; Drug Administ

1990
Acetylsalicylic acid vs. metoprolol in migraine prophylaxis--a double-blind cross-over study.
    Headache, 1990, Volume: 30, Issue:10

    Topics: Adult; Aspirin; Double-Blind Method; Female; Humans; Male; Metoprolol; Migraine Disorders; Recurrenc

1990
Combined low-dose acetylsalicylic acid and dihydroergotamine in migraine prophylaxis. A double-blind, placebo-controlled crossover study.
    Cephalalgia : an international journal of headache, 1988, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Aged; Aspirin; Dihydroergotamine; Dose-Response Relationship, Drug; Double-Blind

1988
[Prevention of migraine with flunarizine and acetylsalicylic acid. A double-blind study].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1987, Volume: 135, Issue:9

    Topics: Adolescent; Aspirin; Child; Clinical Trials as Topic; Double-Blind Method; Drug Administration Sched

1987
A new formulation of aspirin: bioavailability and analgesic efficacy in migraine attacks.
    Cephalalgia : an international journal of headache, 1986, Volume: 6, Issue:1

    Topics: Administration, Oral; Adult; Aspirin; Biological Availability; Clinical Trials as Topic; Humans; Kin

1986
Migraine and platelet aggregation in patients treated with low dose acetylsalicylic acid.
    Headache, 1986, Volume: 26, Issue:6

    Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Ag

1986
Double-blind controlled study of paramax in the acute treatment of common and classical migraine.
    The British journal of clinical practice, 1985, Volume: 39, Issue:10

    Topics: Acetaminophen; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Fem

1985
Analysis of symptoms of patients with headaches and their response to treatment with ergot derivatives.
    The Quarterly journal of medicine, 1968, Volume: 37, Issue:146

    Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Ergonovine; Ergotamine; Female; Headache

1968

Other Studies

147 other studies available for aspirin and Migraine Disorders

ArticleYear
2022 Taiwan Guidelines for Acute Treatment of Migraine.
    Acta neurologica Taiwanica, 2022, Jun-30, Volume: 31(2)

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin G

2022
Predictors of treatment-response to caffeine combination products, acetaminophen, acetylsalicylic acid (aspirin), and nonsteroidal anti-inflammatory drugs in acute treatment of episodic migraine.
    Headache, 2023, Volume: 63, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Female

2023
A Common Drug May Help Patients With Debilitating Migraine Headaches.
    The American journal of medicine, 2020, Volume: 133, Issue:4

    Topics: Aspirin; Health Personnel; Humans; Migraine Disorders

2020
A trial of antithrombotic therapy in patients with refractory migraine and antiphospholipid antibodies: A retrospective study of 75 patients.
    Lupus, 2021, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Aspirin; Child; Cl

2021
Flunarizine and Aspirin for Transient Hemiparesis in Sturge-Weber Syndrome.
    Neuropediatrics, 2019, Volume: 50, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child, Preschool; Electroencephalography; Female;

2019
[Aspirin for migraine in pregnancy. This recommendation seems questionable].
    MMW Fortschritte der Medizin, 2013, Nov-07, Volume: 155, Issue:19

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Contraindications; Female; Humans; Ibuprofen; Infa

2013
Aspirin with or without antiemetic for acute migraine headaches in adults.
    American family physician, 2014, Feb-01, Volume: 89, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Humans; Migraine Disorders

2014
PURLs: treating migraine: the case for aspirin.
    The Journal of family practice, 2014, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Double-Blind Method; Drug Administration Schedule; Drug Therapy, C

2014
[Migraine: treatment and prevention].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:9

    Topics: Acupuncture Therapy; Acute Disease; Analgesics; Aspirin; Botulinum Toxins, Type A; Combined Modality

2014
Antiplatelet therapy: Clopidogrel plus aspirin reduces migrane attacks after ASD closure.
    Nature reviews. Cardiology, 2016, Volume: 13, Issue:1

    Topics: Aspirin; Cardiac Catheterization; Cardiac Surgical Procedures; Female; Headache Disorders, Secondary

2016
Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease.
    Neurology, 2008, Aug-12, Volume: 71, Issue:7

    Topics: Aged; Aspirin; Cardiovascular Diseases; Female; Genetic Predisposition to Disease; Humans; Methylene

2008
More to be said on "Triptans vs other drugs for acute migraine. Are there differences in efficacy?".
    Headache, 2009, Volume: 49, Issue:2

    Topics: Acetaminophen; Analgesics; Aspirin; Dosage Forms; Humans; Ibuprofen; Migraine Disorders; Randomized

2009
Treatment choices and patterns in migraine patients with and without a cardiovascular risk profile.
    Cephalalgia : an international journal of headache, 2009, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Aspirin; Cardiovascular Diseases; Drug Combinations; Ergotamine; Female; Hu

2009
[Triptans versus other migraine medicine--secondary publication].
    Ugeskrift for laeger, 2009, Apr-27, Volume: 171, Issue:18

    Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Migraine

2009
[Sporadic hemiplegic migraine-like headache in a patient with systemic lupus erythematosus].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:5

    Topics: 1-Naphthylamine; Adult; Aspirin; Calcium Channel Blockers; Diagnosis, Differential; Female; Hemipleg

2010
Triptan therapy in migraine.
    The New England journal of medicine, 2010, 09-30, Volume: 363, Issue:14

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Indomethacin; Injections, Intravenous; Ket

2010
Feverfew. Bachelor's buttons, Featherfew (Tanacetum parthenium L. aka Chrysanthemum parthenium L. aka Pyrethrum parthenium L.).
    Journal of primary health care, 2010, Dec-01, Volume: 2, Issue:4

    Topics: Arthritis, Rheumatoid; Aspirin; Drug Interactions; Gastrointestinal Diseases; Humans; Hypersensitivi

2010
Letter by Bhindi and Ormerod regarding article, "Lack of association between migraine headache and patent foramen ovale: results of a case-control study".
    Circulation, 2010, Dec-14, Volume: 122, Issue:24

    Topics: Aspirin; Case-Control Studies; Foramen Ovale, Patent; Humans; Migraine Disorders

2010
Case reports on two patients with episodic vertigo, fluctuating hearing loss and migraine responding to prophylactic drugs for migraine. Menière's disease or migraine-associated vertigo?
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2010, Volume: 30, Issue:4

    Topics: Adult; Aspirin; Female; Hearing Loss, Sensorineural; Humans; Meniere Disease; Middle Aged; Migraine

2010
Aspirin is first-line treatment for migraine and episodic tension-type headache regardless of headache intensity.
    Headache, 2012, Volume: 52, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Cross-Over Studie

2012
Clinical reasoning: a 62-year-old migraineur with a new kind of headache attacks.
    Neurology, 2012, Feb-21, Volume: 78, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Magnetic Resonance Angiography; Male; Migr

2012
Aspirin's effect on platelet inhibition in migraineurs.
    Headache, 2012, Volume: 52, Issue:8

    Topics: Adult; Aspirin; Blood Platelets; Female; Humans; Male; Middle Aged; Migraine Disorders; Myocardial I

2012
[Self-medication of regular headache: a community pharmacy-based survey in Belgium].
    Journal de pharmacie de Belgique, 2012, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster

2012
Overuse of paracetamol caffeine aspirin powders affects cerebral glucose metabolism in chronic migraine patients.
    European journal of neurology, 2013, Volume: 20, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Br

2013
Successful treatment of cerebral venous sinus thrombosis with the Solitaire FR thrombectomy device.
    Journal of neurointerventional surgery, 2013, Volume: 5, Issue:6

    Topics: Anticoagulants; Aspirin; Cerebral Angiography; Endovascular Procedures; Female; Follow-Up Studies; H

2013
Migraine and subsequent risk of breast cancer: a prospective cohort study.
    Cancer causes & control : CCC, 2013, Volume: 24, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Breast Neoplasms; Carcinoma; Chemoprevention; Cohort Studies; Doub

2013
An old drug for a common disease.
    Journal of neurology, neurosurgery, and psychiatry, 2013, Volume: 84, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Migraine Disorders

2013
Strategies in the treatment of migraine.
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:8

    Topics: Analgesics; Antiemetics; Aspirin; Complementary Therapies; Humans; Lysine; Metoclopramide; Migraine

2002
Treatment of migraine.
    The New England journal of medicine, 2002, Sep-05, Volume: 347, Issue:10

    Topics: Analgesics; Aspirin; Humans; Lysine; Metoclopramide; Migraine Disorders; Riboflavin; Serotonin Recep

2002
The impact of an over-the-counter migraine medication program on quality of life.
    Headache, 2003, Volume: 43, Issue:3

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Drug Pre

2003
[Migraine; current concept and therapy of migrainoid neurodystonia].
    Revista clinica espanola, 1953, Jan-15, Volume: 48, Issue:1

    Topics: Aspirin; Caffeine; Cardiovascular Agents; Ergot Alkaloids; Migraine Disorders

1953
[SPASMO-DOLVIRAN "BAYER" IN GENERAL PRACTICE].
    Deutsches medizinisches Journal, 1964, Feb-05, Volume: 15

    Topics: Aspirin; Caffeine; Codeine; Colic; Family Practice; General Practice; Humans; Migraine Disorders; Ph

1964
[USE OF TH-2152 IN PAINFUL SYNDROMES].
    Gazette medicale de France, 1964, Jun-10, Volume: 71

    Topics: Abscess; Analgesia; Aspirin; Back Pain; Bicarbonates; Biomedical Research; Burns; Craniocerebral Tra

1964
[TRIALS WITH TH-2152 (CATALGINE). (APROPOS OF 397 CASES)].
    Gazette medicale de France, 1964, Jun-10, Volume: 71

    Topics: Arthritis; Aspirin; Bicarbonates; Biomedical Research; Headache; Humans; Influenza, Human; Joint Dis

1964
DRUGS FOR HEADACHE OF MIGRAINOUS, VASCULAR OR MUSCULAR ORIGIN.
    Canadian Medical Association journal, 1964, Jul-25, Volume: 91

    Topics: Aspirin; Caffeine; Cardiovascular Agents; Ergot Alkaloids; Ergotamine; Headache; Humans; Meprobamate

1964
Abnormal habituation of 'nociceptive' blink reflex in migraine--evidence for increased excitability of trigeminal nociception.
    Cephalalgia : an international journal of headache, 2003, Volume: 23, Issue:8

    Topics: Adult; Analysis of Variance; Aspirin; Blinking; Female; Follow-Up Studies; Habituation, Psychophysio

2003
[More than six billions Euro costs due to illness days. Migraine therapy counts].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Cost of Ill

2003
[Migraine, inflammation, genes. New risk factors for stroke].
    MMW Fortschritte der Medizin, 2003, Dec-18, Volume: 145, Issue:51-52

    Topics: Adult; Arteriosclerosis; Aspirin; C-Reactive Protein; Case-Control Studies; Contraceptives, Oral; Fe

2003
[Treatment of migraine].
    Duodecim; laaketieteellinen aikakauskirja, 2004, Volume: 120, Issue:8

    Topics: Aspirin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination;

2004
[Drug-induced headache and pain reduction medication with amitriptyline in an 11-year old pupil].
    Der Nervenarzt, 2004, Volume: 75, Issue:5

    Topics: Amitriptyline; Analgesics; Antihypertensive Agents; Aspirin; Child; Dipyrone; Headache Disorders; Hu

2004
[Magnyl 75 mg daily as prevention against migraine?].
    Ugeskrift for laeger, 2005, Feb-14, Volume: 167, Issue:7

    Topics: Aspirin; Drug Combinations; Humans; Magnesium Oxide; Migraine Disorders

2005
Magnetic resonance imaging changes in a patient with migraine attack and transient global amnesia after cardiac catheterization.
    CNS spectrums, 2005, Volume: 10, Issue:12

    Topics: Amnesia, Transient Global; Anti-Inflammatory Agents, Non-Steroidal; Aortic Stenosis, Subvalvular; As

2005
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial--a comment.
    Headache, 2006, Volume: 46, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine;

2006
A comment on acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
    Headache, 2006, Volume: 46, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine;

2006
Acute migraine treatment: patterns of use and satisfaction in a clinical population.
    Headache, 2006, Volume: 46, Issue:5

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffein

2006
[Acetylsalicylic acid in self-medication of migraine. A pharmacy-based observational study].
    Schmerz (Berlin, Germany), 2007, Volume: 21, Issue:1

    Topics: Adult; Aspirin; Community Pharmacy Services; Drug Utilization; Female; Germany; Health Surveys; Huma

2007
From the nutcracker-phenomenon of the left renal vein to the midline congestion syndrome as a cause of migraine, headache, back and abdominal pain and functional disorders of pelvic organs.
    Medical hypotheses, 2007, Volume: 68, Issue:6

    Topics: Abdominal Pain; Adolescent; Aspirin; Back Pain; Child; Child, Preschool; Constriction, Pathologic; D

2007
Can chronic fatigue symptoms associated with nutcracker phenomenon be treated with aspirin?
    Medical hypotheses, 2007, Volume: 69, Issue:3

    Topics: Adolescent; Angioplasty, Balloon; Aorta; Aspirin; Child; Child, Preschool; Fatigue; Fatigue Syndrome

2007
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial--a comment.
    Headache, 2007, Volume: 47, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Enzyme Inhibitors; Humans; Migraine Diso

2007
[Aspirin. Treatment of migraine and tension headaches].
    Medizinische Monatsschrift fur Pharmazeuten, 2007, Volume: 30, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Migraine Disorders; Tension-Type Headache

2007
Are we ignoring the elephant in the room?
    Archives of internal medicine, 2007, Nov-12, Volume: 167, Issue:20

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Artery Disease; Cyclooxygenase 2 Inhibito

2007
[Interval therapy of migraine. Pharmacological bases].
    Fortschritte der Medizin, 1984, Mar-29, Volume: 102, Issue:12

    Topics: Adrenergic beta-Antagonists; Aspirin; Blood Vessels; Calcium Channel Blockers; Cerebrovascular Circu

1984
Drugs for migraine.
    The Medical letter on drugs and therapeutics, 1984, Oct-26, Volume: 26, Issue:673

    Topics: Adrenergic beta-Antagonists; Aspirin; Calcium Channel Blockers; Ergot Alkaloids; Humans; Migraine Di

1984
5-OH-Tryptophane in migraine: clinical and neurophysiological considerations.
    Journal of neurology, 1981, Volume: 225, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Aspirin; Female; Humans; Male; Middle Aged; Migraine Disorders; Nocicept

1981
Platelet behavior in classic migraine: responsiveness to small doses of aspirin.
    Thrombosis and haemostasis, 1983, Apr-28, Volume: 49, Issue:2

    Topics: Adult; Aspirin; beta-Thromboglobulin; Blood Platelets; Humans; Middle Aged; Migraine Disorders

1983
Treatment of the acute migraine attack--current status.
    Cephalalgia : an international journal of headache, 1983, Volume: 3, Issue:1

    Topics: Acetaminophen; Aspirin; Drug Therapy, Combination; Ergotamine; Ergotamines; Humans; Metoclopramide;

1983
Salicylate prophylaxis in migraine.
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1984, Volume: 135, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Female; Humans; Male; Middle Aged; Migraine Disorders; Platelet Ag

1984
Headache--diagnosis and effective management.
    The Western journal of medicine, 1984, Volume: 140, Issue:6

    Topics: Analgesics; Aspirin; Barbiturates; Caffeine; Cluster Headache; Drug Combinations; Ergotamine; Headac

1984
A plain man's guide to the management of migraine.
    British medical journal (Clinical research ed.), 1982, Apr-10, Volume: 284, Issue:6322

    Topics: Acetaminophen; Aspirin; Ergotamine; Headache; Humans; Metoclopramide; Migraine Disorders; Sleep

1982
Propranolol and acetylsalicylic acid in migraine prophylaxis. Double-blind crossover study.
    Acta neurologica Scandinavica, 1983, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Mid

1983
How I manage migraine.
    Australian family physician, 1981, Volume: 10, Issue:8

    Topics: Aspirin; Ergotamine; Female; Humans; Metoclopramide; Migraine Disorders; Relaxation Therapy; Tranqui

1981
The use of platelet inhibitors in migraine.
    Advances in neurology, 1982, Volume: 33

    Topics: Adult; Aged; Aspirin; Blood Platelets; Dipyridamole; Drug Therapy, Combination; Female; Humans; Male

1982
Aspirin treatment of migraine attacks: plasma drug level data.
    Cephalalgia : an international journal of headache, 1982, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aspirin; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle

1982
Aspirin treatment of migraine attacks: clinical observations.
    Cephalalgia : an international journal of headache, 1982, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Child; Female; Humans; Male; Middle Aged; Migraine Disorders; Rese

1982
New approach in migraine prevention.
    The Laryngoscope, 1982, Volume: 92, Issue:10 Pt 1

    Topics: Aspirin; Dipyridamole; Humans; Migraine Disorders

1982
Blood platelets and neurological dysfunction.
    Developmental medicine and child neurology, 1982, Volume: 24, Issue:5

    Topics: Aspirin; Blood Platelets; Child; Dipyridamole; Humans; Ischemic Attack, Transient; Migraine Disorder

1982
Cerebral infarction and migraine.
    Neurology, 1980, Volume: 30, Issue:4

    Topics: Aspirin; Cerebral Infarction; Humans; Migraine Disorders; Propranolol

1980
Migraine prophylaxis: a new approach.
    The Laryngoscope, 1981, Volume: 91, Issue:9 Pt 1

    Topics: Adult; Aged; Aspirin; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Female; Humans;

1981
[Thrombocythemia as cause of migraine accompagnée].
    Deutsche medizinische Wochenschrift (1946), 1980, Apr-11, Volume: 105, Issue:15

    Topics: Aspirin; Blood Platelet Disorders; Child; Female; Humans; Migraine Disorders

1980
Paracetamol (acetaminophen) versus acetylsalicylic acid in migraine.
    European neurology, 1980, Volume: 19, Issue:3

    Topics: Acetaminophen; Acute Disease; Aspirin; Diazepam; Drug Evaluation; Drug Therapy, Combination; Humans;

1980
Newer drug therapies for headache.
    Postgraduate medicine, 1980, Volume: 68, Issue:1

    Topics: Antidepressive Agents; Aspirin; Bromocriptine; Clonidine; Cluster Headache; Dipyridamole; Headache;

1980
Mild analgesics as an alternative to ergotamine in migraine. A comparative trial with acetylsalicylic acid, ergotamine tartrate, and a dextropropoxyphene compound.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:10

    Topics: Adult; Aspirin; Dextropropoxyphene; Double-Blind Method; Ergotamine; Female; Humans; Middle Aged; Mi

1980
Anti-migraine compounds fail to modulate the propagation of cortical spreading depression in the cat.
    European neurology, 1994, Volume: 34, Issue:1

    Topics: Analgesics; Animals; Aspirin; Cats; Cerebral Cortex; Clonazepam; Cortical Spreading Depression; Dihy

1994
Migraine.
    The Journal of family practice, 1993, Volume: 37, Issue:3

    Topics: Acetaminophen; Adult; Aspirin; Child; Diphenhydramine; Histamine H1 Antagonists; Humans; Ibuprofen;

1993
Anorectal stenosis in patients with prolonged use of suppositories containing paracetamol and acetylsalicylic acid.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:11

    Topics: Acetaminophen; Administration, Rectal; Adult; Anus Diseases; Aspirin; Constriction, Pathologic; Drug

1993
Visual field effects of classical migraine.
    Brain and cognition, 1993, Volume: 21, Issue:2

    Topics: Adult; Aspirin; Brain; Functional Laterality; Humans; Male; Migraine Disorders; Photic Stimulation;

1993
[Aspirin: as recommended by WHO].
    La Clinica terapeutica, 1993, Volume: 142, Issue:3

    Topics: Analgesics; Aspirin; Dose-Response Relationship, Drug; Headache; Humans; Migraine Disorders; World H

1993
[Rectal stenosis following prolonged use of suppositories of acetylsalicylic acid and paracetamol. Correction by perineal approach].
    Annales de chirurgie, 1995, Volume: 49, Issue:6

    Topics: Acetaminophen; Aged; Aspirin; Female; Humans; Intestinal Obstruction; Migraine Disorders; Perineum;

1995
Migraine after electroconvulsive therapy.
    Convulsive therapy, 1995, Volume: 11, Issue:3

    Topics: Antidepressive Agents; Aspirin; Combined Modality Therapy; Depressive Disorder; Dose-Response Relati

1995
Effects of antimigraine drugs on retinal spreading depression.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:5

    Topics: Acetaminophen; Adrenergic beta-Antagonists; Adrenochrome; Analgesics, Non-Narcotic; Animals; Aspirin

1996
Diagnosis and management of migraine. Low dose aspirin may be used for prophylaxis.
    BMJ (Clinical research ed.), 1996, Sep-14, Volume: 313, Issue:7058

    Topics: Aspirin; Humans; Migraine Disorders; Randomized Controlled Trials as Topic; Treatment Outcome

1996
Acetaminophen anaphylaxis with aspirin and sodium salicylate sensitivity: a case report.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1996, Volume: 77, Issue:6

    Topics: Acetaminophen; Adolescent; Anaphylaxis; Aspirin; Cross Reactions; Drug Hypersensitivity; Female; Hum

1996
Minimizing migraines.
    Health news (Waltham, Mass.), 1998, Mar-31, Volume: 4, Issue:4

    Topics: Acetaminophen; Aspirin; Caffeine; Drug Combinations; Humans; Migraine Disorders; Riboflavin

1998
[Trigeminal evoked potentials in migraine].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1998, Volume: 98, Issue:4

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Aspirin; Brain; Cerebr

1998
[Acetylsalicylic acid in therapy of migraine].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1998, Volume: 98, Issue:4

    Topics: Aspirin; Chronic Disease; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Middl

1998
Limitations of acetaminophen, aspirin, and caffeine in alleviating migraine.
    Archives of neurology, 1998, Volume: 55, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine;

1998
The inhibition of nicotine-evoked relaxation of the guinea-pig isolated basilar artery by some analgesic drugs and progesterone.
    British journal of pharmacology, 1999, Volume: 126, Issue:4

    Topics: Analgesics; Animals; Aspirin; Basilar Artery; Capsaicin; Dinoprost; Guinea Pigs; In Vitro Techniques

1999
Case report of fibromuscular dysplasia presenting as stroke in a 16-year-old boy.
    Journal of child neurology, 1999, Volume: 14, Issue:4

    Topics: Adolescent; Angiography; Aspirin; Carotid Artery, Internal; Cerebrovascular Disorders; Fibromuscular

1999
[Differentiated therapy of migraine attack].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1999, Volume: 99, Issue:12

    Topics: Adult; Analgesics; Antiemetics; Aspirin; Combined Modality Therapy; Drug Therapy, Combination; Femal

1999
[Migraine treatment].
    Deutsche medizinische Wochenschrift (1946), 2000, Mar-31, Volume: 125, Issue:13

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspir

2000
[Hemiplegic migraine. A series of 5 patients].
    Minerva pediatrica, 2000, Volume: 52, Issue:3

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspiri

2000
[High dosage acetylsalicylic acid for migraine. A classic drug with new appearance].
    MMW Fortschritte der Medizin, 2000, Sep-07, Volume: 142, Issue:36

    Topics: Aspirin; Dosage Forms; Humans; Migraine Disorders; Treatment Outcome

2000
[Effect of migraine medications on monocyte chemotaxis] .
    Anaesthesiologie und Reanimation, 2000, Volume: 25, Issue:4

    Topics: Adult; Analgesics; Aspirin; Chemotaxis, Leukocyte; Dihydroergotamine; Humans; Immune Tolerance; Male

2000
Hypothesized treatment for migraines using low doses of tryptophan, niacin, calcium, caffeine, and acetylsalicylic acid.
    Medical hypotheses, 2001, Volume: 56, Issue:1

    Topics: Adult; Aspirin; Caffeine; Calcium; Dose-Response Relationship, Drug; Drug Therapy, Combination; Huma

2001
What is the optimal strategy for managing acute migraine headaches?
    The Journal of family practice, 2001, Volume: 50, Issue:2

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Disabled Persons; Drug

2001
Warning: the excedrin migraine warning label is inadequate to warn consumers of the risk of medication rebound headache.
    Headache, 1999, Volume: 39, Issue:9

    Topics: Acetaminophen; Adult; Aspirin; Caffeine; Drug Combinations; Drug Labeling; Female; Humans; Migraine

1999
An in vivo rat model to study calcitonin gene related peptide release following activation of the trigeminal vascular system.
    Pain, 2001, Volume: 92, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcitonin Gene-Related Peptide; Disease

2001
[Aspirin, triptan tablet, nasal spray, injection. Even the most severe migraine capitulates].
    MMW Fortschritte der Medizin, 2001, Apr-19, Volume: 143, Issue:16

    Topics: Administration, Intranasal; Aspirin; Cluster Headache; Humans; Injections, Intravenous; Injections,

2001
Low-dose aspirin for migraine prophylaxis in women.
    Cephalalgia : an international journal of headache, 2001, Volume: 21, Issue:3

    Topics: Aspirin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; F

2001
Reduction in the intensity of abortive migraine drug use during coumarin therapy.
    Headache, 2001, Volume: 41, Issue:8

    Topics: Anticoagulants; Aspirin; Coumarins; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erg

2001
[Pulsating exophtalmos and contralateral carotid-cavernous fistula].
    Revue neurologique, 2002, Volume: 158, Issue:5 Pt 1

    Topics: Aged; Aspirin; Blepharoptosis; Carotid-Cavernous Sinus Fistula; Cavernous Sinus Thrombosis; Conjunct

2002
Transitory decrease in platelet monoamine-oxidase activity during migraine attacks.
    Lancet (London, England), 1977, Feb-19, Volume: 1, Issue:8008

    Topics: Adolescent; Adult; Aspirin; Blood Platelets; Blood Proteins; Child; Child, Preschool; Clonidine; Dia

1977
Possible danger of aspirin therapy in presence of migraine.
    Lancet (London, England), 1978, Sep-23, Volume: 2, Issue:8091

    Topics: Aspirin; Humans; Intracranial Embolism and Thrombosis; Male; Migraine Disorders; Platelet Aggregatio

1978
Migraine attacks and increased platelet aggregability induced by oral contraceptives.
    Australian and New Zealand journal of medicine, 1978, Volume: 8, Issue:6

    Topics: Adult; Aspirin; Contraceptives, Oral; Dipyridamole; Drug Combinations; Drug Therapy, Combination; Fe

1978
[Experience with 750 migraine patients at a headache clinic].
    Ugeskrift for laeger, 1979, Sep-03, Volume: 141, Issue:36

    Topics: Acetaminophen; Adult; Aged; Aspirin; Diazepam; Drug Evaluation; Drug Therapy, Combination; Female; H

1979
Cerebral infarction and migraine.
    Neurology, 1979, Volume: 29, Issue:10

    Topics: Aspirin; Cerebral Infarction; Humans; Migraine Disorders; Propranolol

1979
Migraine, platelets, and headache prophylaxis.
    JAMA, 1978, Jan-02, Volume: 239, Issue:1

    Topics: Animals; Aspirin; Blood Platelets; Disease Models, Animal; Humans; Migraine Disorders; Platelet Aggr

1978
Vasomotor phenomena, platelet antagonism and migraine therapy.
    Research and clinical studies in headache, 1978, Volume: 6

    Topics: Aspirin; Ergotamine; Fenoprofen; Humans; Migraine Disorders; Platelet Aggregation; Serotonin; Sulfin

1978
The diagnosis and management of migraine.
    Scottish medical journal, 1978, Volume: 23, Issue:4

    Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Aspirin; Child; Clonidine; Ergotamine; Ergotamines; F

1978
Acetylsalicyclic asthma and migraine - a defect in serotonin (5-HT) uptake in platelets.
    Thrombosis research, 1978, Volume: 13, Issue:6

    Topics: Aspirin; Asthma; Blood Platelets; Humans; Migraine Disorders; Serotonin

1978
[The use of drugs in migraine].
    Minerva medica, 1976, Jun-02, Volume: 67, Issue:28

    Topics: Acetaminophen; Antiemetics; Aspirin; Clonidine; Dihydroergotamine; Ergotamine; Humans; Hypnotics and

1976
Use of platelet antagonists in the treatment of migraine.
    Headache, 1976, Volume: 16, Issue:3

    Topics: Aspirin; Blood Platelets; Dipyridamole; Migraine Disorders; Platelet Aggregation; Sulfinpyrazone

1976
Platelet dysfunction in migraine: effect of self-medication with aspirin.
    Thrombosis and haemostasis, 1976, Nov-30, Volume: 36, Issue:2

    Topics: Aspirin; Humans; Migraine Disorders; Platelet Aggregation; Self Medication

1976
Diseases of the central nervous system. Relief of pain: headache, facial neuralgia, migraine, and phantom limb.
    British medical journal, 1975, Oct-11, Volume: 4, Issue:5988

    Topics: Analgesics; Aspirin; Carbamazepine; Ergotamines; Facial Neuralgia; Giant Cell Arteritis; Headache; H

1975
Editorial: The treatment of acute migraine attacks.
    Headache, 1976, Volume: 15, Issue:4

    Topics: Acetaminophen; Acute Disease; Antiemetics; Aspirin; Caffeine; Ergotamine; Humans; Hypnotics and Seda

1976
Management of migraine.
    Irish medical journal, 1992, Volume: 85, Issue:1

    Topics: Adrenal Cortex Hormones; Aspirin; Clonidine; Humans; Indoles; Migraine Disorders; Propranolol; Sulfo

1992
Migraine.
    Lancet (London, England), 1992, Jul-04, Volume: 340, Issue:8810

    Topics: Aspirin; Female; Humans; Menstrual Cycle; Migraine Disorders; Platelet Activating Factor

1992
Organic dissociative syndrome associated with antimigraine pharmacotherapy.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1991, Volume: 36, Issue:8

    Topics: Adolescent; Analgesics; Aspirin; Barbiturates; Caffeine; Dissociative Disorders; Drug Combinations;

1991
[Acetylsalicylic acid in migraine].
    Medizinische Monatsschrift fur Pharmazeuten, 1991, Volume: 14, Issue:12

    Topics: Aspirin; Germany; Infusions, Intravenous; Migraine Disorders; Societies, Medical

1991
[A staged program for treatment of headache syndromes with low dose acetylsalicylic acid].
    Zeitschrift fur arztliche Fortbildung, 1991, Jan-25, Volume: 85, Issue:1-2

    Topics: Aspirin; Blood; Combined Modality Therapy; Dose-Response Relationship, Drug; Headache; Heparin; Huma

1991
Aspirin prophylaxis for migraine.
    JAMA, 1990, Oct-03, Volume: 264, Issue:13

    Topics: Aspirin; Female; Humans; Male; Migraine Disorders

1990
Treating migraine.
    BMJ (Clinical research ed.), 1989, Aug-19, Volume: 299, Issue:6697

    Topics: Aspirin; Humans; Migraine Disorders

1989
Intravenous lignocaine for migraine headache.
    Australian family physician, 1989, Volume: 18, Issue:12

    Topics: Aspirin; Humans; Injections, Intravenous; Lidocaine; Metoclopramide; Migraine Disorders

1989
Successful aspirin prophylaxis in a child with chronic paroxysmal hemicrania.
    Headache, 1989, Volume: 29, Issue:5

    Topics: Age Factors; Aspirin; Child; Humans; Male; Migraine Disorders; Time Factors

1989
[Antimigrainous agents used in maintenance treatment].
    La Revue du praticien, 1986, Jan-21, Volume: 36, Issue:5

    Topics: Adrenergic beta-Antagonists; Amitriptyline; Aspirin; Benzoxepins; Calcium Channel Blockers; Cinnariz

1986
Platelets and prostaglandins.
    Cephalalgia : an international journal of headache, 1986, Volume: 6 Suppl 4

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Migraine Disorders;

1986
Drugs and platelet activation in migraine and transient ischemic attacks.
    Cephalalgia : an international journal of headache, 1985, Volume: 5 Suppl 2

    Topics: Adult; Aged; Aspirin; beta-Thromboglobulin; Cinnarizine; Female; Flunarizine; Humans; Ischemic Attac

1985
[Alternating hemiplegia in childhood. Clinical report and single photon emission computed tomography study].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1988, Volume: 136, Issue:8

    Topics: Acetazolamide; Aspirin; Brain Ischemia; Cerebral Cortex; Child, Preschool; Chloral Hydrate; Drug The

1988
Vertigo in the pediatric and adolescent age group.
    The Laryngoscope, 1988, Volume: 98, Issue:2

    Topics: Adolescent; Aspirin; Child; Cochlear Duct; Female; Hearing Loss, Functional; Hearing Tests; Humans;

1988
Chronic paroxysmal hemicrania: the first possible bilateral case.
    Cephalalgia : an international journal of headache, 1986, Volume: 6, Issue:1

    Topics: Aged; Aspirin; Chronic Disease; Female; Humans; Indomethacin; Migraine Disorders

1986
[A case of hemiplegic migraine treated with low-dose aspirin].
    Masui. The Japanese journal of anesthesiology, 1986, Volume: 35, Issue:4

    Topics: Adolescent; Aspirin; Female; Hemiplegia; Humans; Migraine Disorders

1986
[Chronic paroxysmal migraine. A review and presentation of 4 new cases].
    Ugeskrift for laeger, 1986, Dec-29, Volume: 149, Issue:1

    Topics: Aspirin; Chronic Disease; Diagnosis, Differential; Female; Humans; Indomethacin; Male; Middle Aged;

1986
Concentration and uptake of 5-hydroxytryptamine in platelets from cluster headache and migraine patients.
    Cephalalgia : an international journal of headache, 1985, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Aged; Aspirin; Blood Platelets; Cluster Headache; Ergotamine; Ergotamines; Female

1985
Efficacy of feverfew as prophylactic treatment of migraine.
    British medical journal (Clinical research ed.), 1985, Nov-23, Volume: 291, Issue:6507

    Topics: Adolescent; Adult; Aged; Aspirin; Child; Female; Humans; Male; Middle Aged; Migraine Disorders; Plan

1985
Migraine--treatment of acute attack.
    Scottish medical journal, 1985, Volume: 30, Issue:4

    Topics: Acetaminophen; Acute Disease; Aspirin; Caffeine; Ergotamine; Ergotamines; Humans; Metoclopramide; Mi

1985
[Pathophysiological basis of anti-aggregation treatment in migraine].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1985, Jan-07, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aspirin; Female; Humans; Migraine Disorders; Platelet Aggregation

1985
[Value of oral primperan in the treatment of migraine].
    Annales de gastroenterologie et d'hepatologie, 1985, May-28, Volume: 21, Issue:2 Pt 2

    Topics: Aspirin; Gastric Emptying; Humans; Metoclopramide; Migraine Disorders

1985
Successful treatment of migraine attacks with intravenous injection of aspirin.
    Journal of neurology, neurosurgery, and psychiatry, 1985, Volume: 48, Issue:11

    Topics: Adult; Aspirin; Female; Humans; Injections, Intravenous; Male; Middle Aged; Migraine Disorders

1985
A classification of headache.
    International ophthalmology clinics, 1970,Fall, Volume: 10, Issue:3

    Topics: Antidepressive Agents; Anxiety; Arteritis; Aspirin; Depression; Ergot Alkaloids; Facial Neuralgia; H

1970
[Amaurosis fugax--differential diagnosis and treatment].
    Lakartidningen, 1974, Jul-24, Volume: 71, Issue:30

    Topics: Anticoagulants; Aspirin; Blindness; Cerebrovascular Disorders; Diagnosis, Differential; Humans; Migr

1974
Absorption of effervescent aspirin during migraine.
    British medical journal, 1974, Nov-02, Volume: 4, Issue:5939

    Topics: Acute Disease; Administration, Oral; Aspirin; Digestive System; Dosage Forms; Female; Humans; Intest

1974
[Octadon N].
    Therapie der Gegenwart, 1974, Volume: 113, Issue:7

    Topics: Analgesics; Aspirin; Caffeine; Drug Combinations; Germany, West; Headache; Humans; Migraine Disorder

1974
Reflections on the treatment of headache.
    Headache, 1972, Volume: 11, Issue:4

    Topics: Animals; Aspirin; Cyproheptadine; Ergotamine; Haplorhini; Headache; Hormones; Humans; Methysergide;

1972
Migraine--treatment of acute attack.
    British medical journal, 1971, Jun-26, Volume: 2, Issue:5764

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Antiemetics; Aspirin; Child; Ergotamine; Female;

1971
Pleurisy and fibrosis of the pleura during methysergide treatment of hemicrania.
    Scandinavian journal of respiratory diseases, 1970, Volume: 51, Issue:3

    Topics: Adult; Aspirin; Codeine; Diazepam; Ergotamine; Female; Functional Laterality; Humans; Male; Methyser

1970
Medical grand rounds from the University of Alabama Medical Center.
    Southern medical journal, 1969, Volume: 62, Issue:2

    Topics: Adult; Anemia, Sickle Cell; Animals; Arthritis, Rheumatoid; Aspirin; Biopsy; Blood Urea Nitrogen; Di

1969
Migraine, gastritis and renal papillary necrosis. A syndrome in chronic nonobstructive pyelonephritis.
    Acta medica Scandinavica, 1966, Volume: 179, Issue:1

    Topics: Acetanilides; Adolescent; Adult; Aged; Analgesics; Aspirin; Barbiturates; Caffeine; Child; Codeine;

1966