aspirin has been researched along with Methemoglobinemia in 7 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Peak methemoglobinemia was 4." | 1.31 | Blood profile during and after hemoglobin substitute administration. ( Gardaz, JP; Jegger, D; Mueller, XM; Tevaearai, HT; von Segesser, LK, 2000) |
| " Swine were dosed (2 g/kg) with 10 g/dL DCLHb, infused intravenously at a rate of 1 mL/kg/min." | 1.29 | Diaspirin crosslinked hemoglobin (DCLHb): bioanalytical studies in swine. ( Bush, S; Marshall, T; Nelson, D; Spicuzza, J, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boucher, AA | 1 |
| Gurunathan, A | 1 |
| Taylor, JM | 1 |
| Ricci, KW | 1 |
| Vadivelu, S | 1 |
| Quinn, CT | 1 |
| GILMAN, A | 1 |
| Bush, S | 1 |
| Marshall, T | 1 |
| Spicuzza, J | 1 |
| Nelson, D | 1 |
| Sefton, W | 1 |
| Pudimat, P | 1 |
| Bina, S | 1 |
| Lojeski, E | 1 |
| Mongan, P | 1 |
| Muldoon, S | 1 |
| Mueller, XM | 1 |
| Tevaearai, HT | 1 |
| Gardaz, JP | 1 |
| Jegger, D | 1 |
| von Segesser, LK | 1 |
| Sutton, E | 1 |
| Soyka, LF | 1 |
| Shahidi, NT | 1 |
1 review available for aspirin and Methemoglobinemia
| Article | Year |
|---|---|
How safe is acetaminophen? Some practical cautions with this widely used agent.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Chemical Phenomena; Chemistry; Child; Drug Synergism; F | 1973 |
6 other studies available for aspirin and Methemoglobinemia
| Article | Year |
|---|---|
Hemoglobin Southampton complicated by cerebral ischemia, moyamoya, and hydroxyurea-induced methemoglobinemia.
Topics: Aspirin; Brain Ischemia; Child; Female; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Hydroxyur | 2019 |
ANALGESIC NEPHROTOXICITY; A PHARMACOLOGICAL ANALYSIS.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Aspirin; Kidney Diseases; Methemoglo | 1964 |
Diaspirin crosslinked hemoglobin (DCLHb): bioanalytical studies in swine.
Topics: Animals; Aspirin; Blood Substitutes; Hemoglobins; Infusions, Intravenous; Iron; Kidney; Liver; Methe | 1994 |
Inhaled nitric oxide attenuates increased pulmonary artery pressure following diaspirin crosslinked hemoglobin (DCLHB) administration.
Topics: Administration, Inhalation; Animals; Aspirin; Blood Gas Analysis; Blood Pressure; Blood Substitutes; | 1999 |
Blood profile during and after hemoglobin substitute administration.
Topics: Analysis of Variance; Animals; Aspirin; Blood Cell Count; Blood Substitutes; Cardiopulmonary Bypass; | 2000 |
Drug-induced hemolysis: biochemical considerations.
Topics: Acetanilides; Anemia, Hemolytic; Aspirin; Biotransformation; Erythrocytes; Glucosephosphate Dehydrog | 1970 |