aspirin has been researched along with Metaplasia in 8 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Metaplasia: A condition in which there is a change of one adult cell type to another similar adult cell type.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Barrett's metaplasia is one of the commonest premalignant lesions in the western world following colorectal adenomas." | 2.47 | Acid reflux and oesophageal cancer. ( Jankowski, J; Nicholson, A, 2011) |
| "Gallbladder stones (cholecystolithiasis) are the main risk factor for gallbladder cancer (GBC), a lethal biliary malignancy with poor survival rates worldwide." | 1.56 | Evaluation of the chemopreventive potentials of ezetimibe and aspirin in a novel mouse model of gallbladder preneoplasia. ( Arrese, M; Bizama, C; Espinoza, JA; Ferreccio, C; García, P; Gómez, N; González, X; Guevara, F; Kalergis, AM; Lobos-González, L; Miquel, JF; Muñoz-Durango, N; Roa, JC; Rosa, L; Saavedra, N; Villegas, J; Wichmann, IA, 2020) |
| "In total, 230 reflux esophagitis, 224 Barrett's esophagus, and 227 esophageal adenocarcinoma and 260 population controls were recruited." | 1.33 | Nonsteroidal anti-inflammatory drugs and the esophageal inflammation-metaplasia-adenocarcinoma sequence. ( Anderson, LA; Comber, H; Ferguson, HR; Johnston, BT; McGuigan, J; Murphy, SJ; Murray, LJ; Reynolds, JV; Watson, RG, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watari, J | 1 |
| Tomita, T | 1 |
| Tozawa, K | 1 |
| Oshima, T | 1 |
| Fukui, H | 1 |
| Miwa, H | 1 |
| Rosa, L | 1 |
| Lobos-González, L | 1 |
| Muñoz-Durango, N | 1 |
| García, P | 1 |
| Bizama, C | 1 |
| Gómez, N | 1 |
| González, X | 1 |
| Wichmann, IA | 1 |
| Saavedra, N | 1 |
| Guevara, F | 1 |
| Villegas, J | 1 |
| Arrese, M | 1 |
| Ferreccio, C | 1 |
| Kalergis, AM | 1 |
| Miquel, JF | 1 |
| Espinoza, JA | 1 |
| Roa, JC | 1 |
| Kim, SG | 1 |
| Jung, HK | 1 |
| Lee, HL | 1 |
| Jang, JY | 1 |
| Lee, H | 1 |
| Kim, CG | 1 |
| Shin, WG | 1 |
| Shin, ES | 1 |
| Lee, YC | 1 |
| Nicholson, A | 1 |
| Jankowski, J | 1 |
| Anderson, LA | 1 |
| Johnston, BT | 1 |
| Watson, RG | 1 |
| Murphy, SJ | 1 |
| Ferguson, HR | 1 |
| Comber, H | 1 |
| McGuigan, J | 1 |
| Reynolds, JV | 1 |
| Murray, LJ | 1 |
| Morgan, G | 1 |
| Reynolds, KW | 1 |
| MacDonald, WC | 1 |
2 reviews available for aspirin and Metaplasia
| Article | Year |
|---|---|
Preventing Metachronous Gastric Cancer after the Endoscopic Resection of Gastric Epithelial Neoplasia: Roles of
Topics: Aspirin; Endoscopic Mucosal Resection; Female; Gastric Mucosa; Gastritis, Atrophic; Helicobacter Inf | 2020 |
Acid reflux and oesophageal cancer.
Topics: Adenocarcinoma; Aspirin; Barrett Esophagus; Cyclooxygenase 2; Esophageal Neoplasms; Esophagitis; Gas | 2011 |
6 other studies available for aspirin and Metaplasia
| Article | Year |
|---|---|
Evaluation of the chemopreventive potentials of ezetimibe and aspirin in a novel mouse model of gallbladder preneoplasia.
Topics: Animals; Aspirin; Chemoprevention; Cholecystolithiasis; Cholesterol; Cholesterol, Dietary; Chronic D | 2020 |
[Guidelines for the diagnosis and treatment of Helicobacter pylori infection in Korea, 2013 revised edition].
Topics: Amoxicillin; Anti-Bacterial Agents; Aspirin; Bismuth; Breath Tests; Clarithromycin; Gastroesophageal | 2013 |
Nonsteroidal anti-inflammatory drugs and the esophageal inflammation-metaplasia-adenocarcinoma sequence.
Topics: Acetaminophen; Adenocarcinoma; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Asp | 2006 |
Correspondence re: R. Kim et al., Etiology of Barrett's metaplasia and esophageal adenocarcinoma. Cancer Epidemiol., Biomark. Prev., 6: 369-377, 1997.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Barrett Esophagus; Cell Transforma | 1998 |
Erosive gastritis with special reference to the role of aspirin and bile.
Topics: Acute Disease; Age Factors; Aged; Animals; Aspirin; Bile; Chronic Disease; Drainage; Female; Gastrec | 1974 |
Correlation of mucosal histology and aspirin intake in chronic gastric ulcer.
Topics: Adult; Aged; Aspirin; Caffeine; Chronic Disease; Epithelium; Female; Gastric Mucosa; Gastritis; Huma | 1973 |