aspirin has been researched along with Mental Disorders in 31 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "TAIST was a randomized, controlled trial assessing the safety and efficacy of tinzaparin versus aspirin in 1484 patients with acute ischemic stroke." | 5.12 | Sex differences in quality of life in stroke survivors: data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST). ( Bath, PM; Boysen, G; De Deyn, PP; Gray, LJ; Leys, D; O'Neill, D; Ringelstein, EB; Sprigg, N, 2007) |
| " Proportional hazard models compared the association between mental disorders and mortality before and after adjusting 5 established quality indicators: reperfusion, aspirin, beta-blockers, angiotensin-converting enzyme inhibitors, and smoking cessation counseling." | 3.71 | Quality of medical care and excess mortality in older patients with mental disorders. ( Bradford, WD; Druss, BG; Krumholz, HM; Radford, MJ; Rosenheck, RA, 2001) |
| "Neuropsychiatric disorders place a very high burden on the global health and economy." | 2.61 | Acetylsalicylic acid and its metabolite gentisic acid may act as adjunctive agents in the treatment of psychiatric disorders. ( Altinoz, MA; Ozpinar, A, 2019) |
| "Aspirin is a non-steroidal anti-inflammatory drug that is an irreversible inhibitor of both cyclooxygenase (COX)-1 and COX-2, It stimulates endogenous production of anti-inflammatory regulatory 'braking signals', including lipoxins, which dampen the inflammatory response and reduce levels of inflammatory biomarkers, including C-reactive protein, tumor necrosis factor-α and interleukin (IL)--6, but not negative immunoregulatory cytokines, such as IL-4 and IL-10." | 2.49 | Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness. ( Berk, M; Davey, CG; Dean, O; Drexhage, H; Maes, M; McNeil, JJ; Moylan, S; O'Neil, A; Sanna, L, 2013) |
| "In many individuals with major neuropsychiatric disorders including depression, bipolar disorder and schizophrenia, their disease characteristics are consistent with a neuroprogressive illness." | 2.49 | Putative neuroprotective agents in neuropsychiatric disorders. ( Anderson, G; Berk, M; Dean, OM; Dodd, S; Maes, M; Moylan, S, 2013) |
| "Patients with mental illness were marginally less likely than those without mental illness to undergo in-hospital angiography (age-adjusted RR 0." | 1.32 | Process of care and outcome after acute myocardial infarction for patients with mental illness in the VA health care system: are there disparities? ( Druss, BG; Normand, SL; Petersen, LA; Rosenheck, RA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (54.84) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 5 (16.13) | 29.6817 |
| 2010's | 6 (19.35) | 24.3611 |
| 2020's | 2 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, J | 1 |
| Shi, Y | 1 |
| Li, J | 1 |
| Zhang, Z | 1 |
| Hybiak, J | 1 |
| Broniarek, I | 1 |
| Kiryczyński, G | 1 |
| Los, LD | 1 |
| Rosik, J | 1 |
| Machaj, F | 1 |
| Sławiński, H | 1 |
| Jankowska, K | 1 |
| Urasińska, E | 1 |
| Altinoz, MA | 1 |
| Ozpinar, A | 1 |
| Victor, K | 1 |
| Skelly, M | 1 |
| Mulcahy, K | 1 |
| Demler, TL | 1 |
| Trigoboff, E | 1 |
| Berk, M | 2 |
| Dean, O | 1 |
| Drexhage, H | 1 |
| McNeil, JJ | 1 |
| Moylan, S | 2 |
| O'Neil, A | 1 |
| Davey, CG | 1 |
| Sanna, L | 1 |
| Maes, M | 2 |
| Aggarwal, N | 1 |
| Kupfer, Y | 1 |
| Chawla, K | 1 |
| Tessler, S | 1 |
| RAWLINGS, KO | 1 |
| Swarbrick, M | 1 |
| Fitzgerald, C | 1 |
| Dodd, S | 1 |
| Anderson, G | 1 |
| Dean, OM | 1 |
| Petersen, LA | 1 |
| Normand, SL | 1 |
| Druss, BG | 3 |
| Rosenheck, RA | 3 |
| SARWER-FONER, GJ | 1 |
| MORRISON, GH | 1 |
| RYAN, RE | 1 |
| Hibel, LC | 1 |
| Granger, DA | 1 |
| Kivlighan, KT | 1 |
| Blair, C | 1 |
| Gray, LJ | 1 |
| Sprigg, N | 1 |
| Bath, PM | 1 |
| Boysen, G | 1 |
| De Deyn, PP | 1 |
| Leys, D | 1 |
| O'Neill, D | 1 |
| Ringelstein, EB | 1 |
| Pavlova, SI | 1 |
| Inoki, R | 1 |
| Bradford, WD | 1 |
| Radford, MJ | 1 |
| Krumholz, HM | 1 |
| Desai, MM | 1 |
| Perlin, JB | 1 |
| Reus, VI | 1 |
| Nicholson, G | 1 |
| Liebling, LI | 1 |
| Hall, RA | 1 |
| Klemm, E | 1 |
| Conzelmann, E | 1 |
| Olesen, AC | 1 |
| Murray, RM | 3 |
| Timbury, GC | 1 |
| Linton, AL | 1 |
| Baker, M | 1 |
| Naess, K | 1 |
| Friedman, D | 1 |
| Moskowitz, MD | 1 |
| Rosen, M | 1 |
| Rossman, M | 1 |
| Sheppard, C | 1 |
| Merlis, S | 1 |
| Gault, MH | 1 |
| Rudwal, TC | 1 |
| Redmond, NI | 1 |
| Christensen, JK | 1 |
| Fischer, PA | 1 |
| Jorgensen, TG | 1 |
| Strandbygaard, N | 1 |
| Buck, IF | 1 |
| Zeff, S | 1 |
| Kalnins, L | 1 |
| Heiser, RA | 1 |
| Bentham, WL | 1 |
| Pollack, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Salicylic Augmentation in Depression[NCT03152409] | Phase 2 | 74 participants (Anticipated) | Interventional | 2018-11-15 | Recruiting | ||
| Reducing Cardiovascular Risk in Adults With Serious Mental Illness Using an Electronic Medical Record-based Clinical Decision Support[NCT02451670] | 10,347 participants (Actual) | Interventional | 2016-01-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
A modifiable risk component for each cardiovascular risk factor not at optimal goal at the time of each encounter was calculated as the difference between total 10-year atherosclerotic cardiovascular disease risk with the patient's actual values and the goal value. Total modifiable cardiovascular risk was calculated by summing the modifiable cardiovascula risk components across cardiovascular risk factors not at optimal goal at the time of the encounter, and was calculated for each enrolled patient at the index visit and each subsequent encounter during the intervention period. Annual rate of change in modifiable cardiovascular risk was estimated from all patient encounters. A comparison of the difference in model-estimated rate of change in modifiable cardiovascular risk at 12 months post-index tested the primary efficacy hypothesis. (NCT02451670)
Timeframe: Index to 12 months post index visit
| Intervention | percentage of annual rate of change (Number) |
|---|---|
| Prioritized Clinical Decision Support | 14.2 |
| Usual Care | 20.8 |
5 reviews available for aspirin and Mental Disorders
| Article | Year |
|---|---|
Aspirin and its pleiotropic application.
Topics: Animals; Aspirin; Female; Humans; Mental Disorders; Neoplasms; Platelet Aggregation Inhibitors; Pre- | 2020 |
Acetylsalicylic acid and its metabolite gentisic acid may act as adjunctive agents in the treatment of psychiatric disorders.
Topics: Anti-Inflammatory Agents; Antioxidants; Aspirin; Bipolar Disorder; Gentisates; Humans; Inflammation; | 2019 |
A review and study of aspirin utilization for the primary prevention of cardiovascular events in a psychiatric population.
Topics: Aged; Aspirin; Cardiovascular Diseases; Humans; Mental Disorders; Middle Aged; Primary Prevention; R | 2018 |
Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Encephalitis; Humans; Mental Disorders; O | 2013 |
Putative neuroprotective agents in neuropsychiatric disorders.
Topics: Animals; Aspirin; Bipolar Disorder; Depressive Disorder; Humans; Lithium; Mental Disorders; Nerve Gr | 2013 |
3 trials available for aspirin and Mental Disorders
| Article | Year |
|---|---|
Sex differences in quality of life in stroke survivors: data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST).
Topics: Activities of Daily Living; Age Factors; Aged; Aspirin; Brain Ischemia; Double-Blind Method; Female; | 2007 |
Psychopathology in systemic lupus erythematosus. I. Psychiatric observations.
Topics: Adolescent; Adult; Affective Symptoms; Aspirin; Azathioprine; Brain Diseases; Clinical Trials as Top | 1973 |
Effects of chlormezanone on anxiety and tension: a double blind study.
Topics: Adolescent; Adult; Aged; Anxiety; Anxiety Disorders; Aspirin; Bipolar Disorder; Chlormezanone; Clini | 1966 |
23 other studies available for aspirin and Mental Disorders
| Article | Year |
|---|---|
Role of risk attitude and time preference in preventive aspirin use adherence.
Topics: Aspirin; Cardiovascular Diseases; Humans; Logistic Models; Medication Adherence; Mental Disorders; P | 2020 |
Altered mental status and complete heart block: an unusual presentation of aspirin toxicity.
Topics: Acidosis; Aged; Aspirin; Female; Heart Block; Humans; Mental Disorders; Pacemaker, Artificial | 2013 |
The use and abuse of aspirin.
Topics: Aspirin; Humans; Mental Disorders; Substance-Related Disorders | 1948 |
The Million Hearts™ initiative: why psychosocial nurses should care.
Topics: Aspirin; Cholesterol; Comorbidity; Health Promotion; Humans; Hypertension; Mental Disorders; Myocard | 2012 |
Process of care and outcome after acute myocardial infarction for patients with mental illness in the VA health care system: are there disparities?
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Aspi | 2003 |
Acute toxic psychosis due to acetyl-salicylic acid.
Topics: Aspirin; Humans; Mental Disorders; Poisoning; Psychoses, Substance-Induced; Psychotic Disorders | 1955 |
TENSION HEADACHE: A NEW AGENT FOR ITS SYMPTOMATIC RELIEF.
Topics: Aspirin; Barbiturates; Caffeine; Diagnosis; Drug Therapy; Headache; Humans; Mental Disorders; Phenac | 1965 |
Individual differences in salivary cortisol: associations with common over-the-counter and prescription medication status in infants and their mothers.
Topics: Adrenocorticotropic Hormone; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Corticotropin- | 2006 |
[Changes in coagulographic indices of patients with cerebral atherosclerosis complicated by mental disorders during the treatment process].
Topics: Aged; Aspirin; Blood Coagulation; Dementia; Drug Therapy, Combination; Female; Humans; Intracranial | 1980 |
[Pharmacology of anti-migraine drugs].
Topics: Aspirin; Ergotamine; Headache; Humans; Inflammation; Mental Disorders; Muscle Contraction; Neuralgia | 1993 |
Quality of medical care and excess mortality in older patients with mental disorders.
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; C | 2001 |
Mental disorders and quality of care among postacute myocardial infarction outpatients.
Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Ambulatory Care; Anticholesteremic Agents; Aspirin | 2002 |
Behavioral side effects of medical drugs.
Topics: Adrenal Cortex Hormones; Aged; Antihypertensive Agents; Antitubercular Agents; Aspirin; Behavior; Ca | 1979 |
Thyroid dysfunction in female psychiatric patients.
Topics: Adult; Age Factors; Aged; Aspirin; Female; Humans; Hypothyroidism; Lithium; Mental Disorders; Middle | 1976 |
Adult-onset metachromatic leucodystrophy presenting without psychiatric symptoms.
Topics: Adult; Aspirin; Biopsy; Diagnosis, Differential; Electrophysiology; Family Health; Humans; Leukodyst | 1989 |
[Mental disorders caused by aspirin poisoning].
Topics: Aspirin; Female; Humans; Mental Disorders; Middle Aged | 1988 |
Analgesic abuse in psychiatric patients.
Topics: Adult; Aged; Anemia; Aspirin; Creatinine; Dyspepsia; Female; Humans; Kidney Diseases; Male; Mental D | 1970 |
The use and abuse of analgesics.
Topics: Analgesics; Aspirin; Female; Humans; Kidney Diseases; Male; Mental Disorders; Scotland; Self Medicat | 1972 |
The origins of analgesic nephropathy.
Topics: Adult; Affective Symptoms; Aged; Alcoholism; Analgesics; Antipyrine; Aspirin; Codeine; Creatinine; F | 1973 |
[Risks in long-term treatment with analgesics].
Topics: Acetaminophen; Analgesics; Antipyrine; Aspirin; Caffeine; Diuresis; Drug Combinations; Humans; Kidne | 1973 |
Analgesic habits of 500 veterans: incidence and complications of abuse.
Topics: Adult; Aged; Analgesics; Anemia; Arthritis; Aspirin; Caffeine; Canada; Codeine; Gastrointestinal Hem | 1968 |
[Psychiatric and gastroenterological evaluation of patients with duodenal ulcer confirmed at operation. 100 patients studied by preoperative psychiatric interview and enlarged histamine test with special reference to the relation between psychic factors a
Topics: Adolescent; Adult; Age Factors; Aged; Alcohol Drinking; Aspirin; Character; Child; Drinking Behavior | 1970 |
The treatment of intraoral chemical burns.
Topics: Adolescent; Adult; Aged; Aspirin; Borates; Burns, Chemical; Child; Chlorpromazine; Humans; Mental Di | 1965 |