aspirin has been researched along with Mast Cell Activation Disease in 8 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with clonal mast cell activation syndromes (MCAS) including cutaneous and systemic mastocytosis (SM) may present with symptoms of mast cell activation, but in addition can have organ damage from the local effects of tissue infiltration by clonal mast cells." | 2.61 | Mast Cell Activation Syndrome and Mastocytosis: Initial Treatment Options and Long-Term Management. ( Butterfield, J; Castells, M, 2019) |
| "Patients with mastocytosis are at increased risk of anaphylaxis." | 1.48 | Low frequency of acetyl salicylic acid hypersensitivity in mastocytosis: The results of a double-blind, placebo-controlled challenge study. ( Hermans, MAW; van Daele, PLA; van der Vet, SQA; van Hagen, PM; van Wijk, RG, 2018) |
| "Treatment with aspirin resulted in normalization of 11beta-PGF(2)(alpha) excretion in the 2 patients with elevated baseline levels and in prevention of symptoms in all 4 patients." | 1.35 | Prevention of mast cell activation disorder-associated clinical sequelae of excessive prostaglandin D(2) production. ( Butterfield, JH; Weiler, CR, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hermans, MAW | 1 |
| van der Vet, SQA | 1 |
| van Hagen, PM | 1 |
| van Wijk, RG | 1 |
| van Daele, PLA | 1 |
| Castells, M | 1 |
| Butterfield, J | 1 |
| Butterfield, JH | 3 |
| Weiler, CR | 1 |
| Kao, PC | 1 |
| Klee, GC | 1 |
| Yocum, MW | 2 |
| Gharib, H | 1 |
| Worobec, AS | 1 |
| Pankow, W | 1 |
| Ehlenz, K | 1 |
| Buhr, T | 1 |
| Pflüger, KH | 1 |
| von Wichert, P | 1 |
| Lorcerie, B | 1 |
| Arveux, I | 1 |
| Chauffert, B | 1 |
| Dalac, S | 1 |
| Lambert, D | 1 |
| Martin, F | 1 |
2 reviews available for aspirin and Mast Cell Activation Disease
| Article | Year |
|---|---|
Mast Cell Activation Syndrome and Mastocytosis: Initial Treatment Options and Long-Term Management.
Topics: Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cromo | 2019 |
Treatment of systemic mast cell disorders.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Antineoplastic Agents; Aspirin; Cholinergic An | 2000 |
6 other studies available for aspirin and Mast Cell Activation Disease
| Article | Year |
|---|---|
Low frequency of acetyl salicylic acid hypersensitivity in mastocytosis: The results of a double-blind, placebo-controlled challenge study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Double-Blind Method; Drug Hypersensitivity; | 2018 |
Prevention of mast cell activation disorder-associated clinical sequelae of excessive prostaglandin D(2) production.
Topics: Adult; Anaphylaxis; Aspirin; Female; Histamine Release; Humans; Male; Mast Cells; Mastocytosis; Midd | 2008 |
Aspirin idiosyncrasy in systemic mast cell disease: a new look at mediator release during aspirin desensitization.
Topics: Adult; Aspirin; Calcitonin; Calcitonin Gene-Related Peptide; Chymases; Desensitization, Immunologic; | 1995 |
Increased plasma calcitonin levels in systemic mast cell disease.
Topics: Adult; Anaphylaxis; Aspirin; Calcitonin; Creatinine; Desensitization, Immunologic; Histamine; Humans | 1994 |
[Osteoporotic vertebral fractures in systemic mastocytosis without skin involvement].
Topics: Aspirin; Bone Marrow Examination; Calcitonin; Calcium; Cholecalciferol; Diagnosis, Differential; Fem | 1992 |
Aspirin and systemic mastocytosis.
Topics: Aspirin; Female; Gastrointestinal Motility; Humans; Mastocytosis; Middle Aged; Vomiting | 1989 |