Page last updated: 2024-10-23

aspirin and Malaria

aspirin has been researched along with Malaria in 9 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"Low dose aspirin (LDA) is an effective strategy to reduce preterm birth."9.51The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries. ( Bauserman, M; Bose, CL; Carlo, WA; Chomba, E; Derman, RJ; Esamai, F; Goldenberg, RL; Hemingway-Foday, J; Hoffman, M; Jessani, S; Koso-Thomas, M; Leuba, SI; Liechty, EA; Lokangaka, A; McClure, EM; Meshnick, SR; Moore, J; Nolen, TL; Patterson, J; Saleem, S; Tsehfu, A, 2022)
"We prospectively recruited women from sites in the Democratic Republic of the Congo (DRC), Kenya, and Zambia who participated in the ASPIRIN (Aspirin Supplementation for Pregnancy Indicated risk Reduction In Nulliparas) trial."5.51Predictors of Plasmodium falciparum Infection in the First Trimester Among Nulliparous Women From Kenya, Zambia, and the Democratic Republic of the Congo. ( Bauserman, M; Bose, CL; Bucher, SL; Carlo, WA; Chomba, E; Derman, RJ; Esamai, F; Goldenberg, RL; Hemingway-Foday, J; Hoffman, M; Jessani, S; Koso-Thomas, M; Leuba, SI; Liechty, EA; Lokangaka, A; McClure, EM; Moore, J; Nolen, T; Olshan, A; Powers, KA; Saleem, S; Taylor, SM; Tshefu, A; Westreich, D, 2022)
"Low dose aspirin (LDA) is an effective strategy to reduce preterm birth."5.51The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries. ( Bauserman, M; Bose, CL; Carlo, WA; Chomba, E; Derman, RJ; Esamai, F; Goldenberg, RL; Hemingway-Foday, J; Hoffman, M; Jessani, S; Koso-Thomas, M; Leuba, SI; Liechty, EA; Lokangaka, A; McClure, EM; Meshnick, SR; Moore, J; Nolen, TL; Patterson, J; Saleem, S; Tsehfu, A, 2022)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's2 (22.22)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Leuba, SI2
Westreich, D1
Bose, CL2
Powers, KA1
Olshan, A1
Taylor, SM1
Tshefu, A1
Lokangaka, A2
Carlo, WA2
Chomba, E2
Liechty, EA2
Bucher, SL1
Esamai, F2
Jessani, S2
Saleem, S2
Goldenberg, RL2
Moore, J2
Nolen, T1
Hemingway-Foday, J2
McClure, EM2
Koso-Thomas, M2
Derman, RJ2
Hoffman, M2
Bauserman, M2
Nolen, TL1
Tsehfu, A1
Patterson, J1
Meshnick, SR1
Amekoudi, EY1
Sabi, KA1
Noto Kadou Kaza, B1
Fine, PG1
Stanos, S1
McMorran, BJ1
Marshall, VM1
de Graaf, C1
Drysdale, KE1
Shabbar, M1
Smyth, GK1
Corbin, JE1
Alexander, WS1
Foote, SJ1
Greenbaum, DC1
FitzGerald, GA1
Ezeamuzie, IC1
Ojinnaka, MC1
Uzogara, EO1
Oji, SE1
Willcox, ML1
Ahmed, I1
Olowe, O1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity[NCT05757167]Phase 42,500 participants (Anticipated)Interventional2023-11-06Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for aspirin and Malaria

ArticleYear
Predictors of Plasmodium falciparum Infection in the First Trimester Among Nulliparous Women From Kenya, Zambia, and the Democratic Republic of the Congo.
    The Journal of infectious diseases, 2022, 06-01, Volume: 225, Issue:11

    Topics: Aspirin; Democratic Republic of the Congo; Female; Humans; Kenya; Malaria; Malaria, Falciparum; Plas

2022
The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries.
    BMC pregnancy and childbirth, 2022, Apr-10, Volume: 22, Issue:1

    Topics: Aspirin; Female; Humans; Infant, Newborn; Malaria; Perinatal Death; Perinatal Mortality; Pregnancy;

2022

Other Studies

7 other studies available for aspirin and Malaria

ArticleYear
[Profound anemia, hemoglobinuria ... where to stop in the etiological investigation?].
    Nephrologie & therapeutique, 2014, Volume: 10, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Anemia, Hemolytic; Aspirin; Blackwater Fever; Erythrocyte Transfusi

2014
NSAIDs supplement forward.
    Pain medicine (Malden, Mass.), 2013, Volume: 14 Suppl 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2 Inhibitors; History, 18th Century

2013
Platelets kill intraerythrocytic malarial parasites and mediate survival to infection.
    Science (New York, N.Y.), 2009, Feb-06, Volume: 323, Issue:5915

    Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Erythrocytes; Female; Humans; In Situ Nick

2009
Platelets, pyrexia, and plasmodia.
    The New England journal of medicine, 2009, Jul-30, Volume: 361, Issue:5

    Topics: Animals; Aspirin; Blood Platelets; Erythrocytes; Humans; Malaria; Plasmodium chabaudi; Plasmodium fa

2009
Anti-inflammatory, antipyretic and anti-malarial activities of a West African medicinal plant--Picralima nitida.
    African journal of medicine and medical sciences, 1994, Volume: 23, Issue:1

    Topics: Africa; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Antimalarials; Aspirin; Chloroq

1994
Salicylates, nitric oxide, malaria, and Reye's syndrome.
    Lancet (London, England), 2001, Jun-09, Volume: 357, Issue:9271

    Topics: Aspirin; Cause of Death; Child; Developing Countries; Female; Health Promotion; Humans; Madagascar;

2001
Haemoglobinuria in Nigerian children.
    The African journal of medical sciences, 1971, Volume: 2, Issue:2

    Topics: Acetaminophen; Aspirin; Autopsy; Brain; Caffeine; Child; Child, Preschool; Coombs Test; Diagnosis, D

1971