aspirin has been researched along with Malaria, Falciparum in 6 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We prospectively recruited women from sites in the Democratic Republic of the Congo (DRC), Kenya, and Zambia who participated in the ASPIRIN (Aspirin Supplementation for Pregnancy Indicated risk Reduction In Nulliparas) trial." | 5.51 | Predictors of Plasmodium falciparum Infection in the First Trimester Among Nulliparous Women From Kenya, Zambia, and the Democratic Republic of the Congo. ( Bauserman, M; Bose, CL; Bucher, SL; Carlo, WA; Chomba, E; Derman, RJ; Esamai, F; Goldenberg, RL; Hemingway-Foday, J; Hoffman, M; Jessani, S; Koso-Thomas, M; Leuba, SI; Liechty, EA; Lokangaka, A; McClure, EM; Moore, J; Nolen, T; Olshan, A; Powers, KA; Saleem, S; Taylor, SM; Tshefu, A; Westreich, D, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, ME | 1 |
| Parrott, EE | 1 |
| Singh, R | 1 |
| Nelson, SW | 1 |
| Leuba, SI | 1 |
| Westreich, D | 1 |
| Bose, CL | 1 |
| Powers, KA | 1 |
| Olshan, A | 1 |
| Taylor, SM | 1 |
| Tshefu, A | 1 |
| Lokangaka, A | 1 |
| Carlo, WA | 1 |
| Chomba, E | 1 |
| Liechty, EA | 1 |
| Bucher, SL | 1 |
| Esamai, F | 1 |
| Jessani, S | 1 |
| Saleem, S | 1 |
| Goldenberg, RL | 1 |
| Moore, J | 1 |
| Nolen, T | 1 |
| Hemingway-Foday, J | 1 |
| McClure, EM | 1 |
| Koso-Thomas, M | 1 |
| Derman, RJ | 1 |
| Hoffman, M | 1 |
| Bauserman, M | 1 |
| Sirima, SB | 1 |
| Konaté, A | 1 |
| Tiono, AB | 1 |
| Convelbo, N | 1 |
| Cousens, S | 1 |
| Pagnoni, F | 1 |
| Tchuinkam, T | 1 |
| Mulder, B | 1 |
| Dechering, K | 1 |
| Stoffels, H | 1 |
| Verhave, JP | 1 |
| Cot, M | 1 |
| Carnevale, P | 1 |
| Meuwissen, JH | 1 |
| Robert, V | 1 |
| Keri, JE | 1 |
| Thomas, K | 1 |
| Berman, B | 1 |
| Falabella, A | 1 |
| Hemmer, CJ | 1 |
| Kern, P | 1 |
| Holst, FG | 1 |
| Nawroth, PP | 1 |
| Dietrich, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity[NCT05757167] | Phase 4 | 2,500 participants (Anticipated) | Interventional | 2023-11-06 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for aspirin and Malaria, Falciparum
| Article | Year |
|---|---|
Predictors of Plasmodium falciparum Infection in the First Trimester Among Nulliparous Women From Kenya, Zambia, and the Democratic Republic of the Congo.
Topics: Aspirin; Democratic Republic of the Congo; Female; Humans; Kenya; Malaria; Malaria, Falciparum; Plas | 2022 |
Neither heparin nor acetylsalicylic acid influence the clinical course in human Plasmodium falciparum malaria: a prospective randomized study.
Topics: Aspirin; Fibrinogen; Heparin; Humans; L-Lactate Dehydrogenase; Malaria, Falciparum; Partial Thrombop | 1991 |
4 other studies available for aspirin and Malaria, Falciparum
| Article | Year |
|---|---|
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
Topics: Antimalarials; Apicoplasts; Chloroplasts; DNA; DNA-Directed DNA Polymerase; Drug Discovery; Exonucle | 2014 |
Early treatment of childhood fevers with pre-packaged antimalarial drugs in the home reduces severe malaria morbidity in Burkina Faso.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Aspirin; Burkina Faso; Child, Preschool; Chl | 2003 |
Experimental infections of Anopheles gambiae with Plasmodium falciparum of naturally infected gametocyte carriers in Cameroon: factors influencing the infectivity to mosquitoes.
Topics: ABO Blood-Group System; Adolescent; Adult; Age Factors; Amodiaquine; Animals; Anopheles; Aspirin; Bo | 1993 |
Purpura fulminans in a patient with malaria.
Topics: Adult; Aspirin; Drug Therapy, Combination; Female; Follow-Up Studies; Heparin; Humans; IgA Vasculiti | 2000 |