aspirin has been researched along with Lymph Node Metastasis in 12 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In an attempt to increase the antitumor effect of cisplatin (50 mg/m2) and dacarbazine (350 mg/m2), each repeated on days 1 to 3 every 4 weeks in patients with metastatic melanoma, tamoxifen was added to the regimen." | 9.07 | High-dose cisplatin with dacarbazine and tamoxifen in the treatment of metastatic melanoma. ( Buzaid, AC; Durivage, HJ; Murren, JR, 1991) |
| " Therefore, we examined the association between recent (1 year) prediagnostic use of aspirin (COX1/COX2 inhibitor), lymph node involvement at breast cancer diagnosis, and breast cancer-specific mortality." | 7.80 | Recent prediagnostic aspirin use, lymph node involvement, and 5-year mortality in women with stage I-III breast cancer: a nationwide population-based cohort study. ( Barron, TI; Bennett, K; Flahavan, EM; Sharp, L; Visvanathan, K, 2014) |
| "Aspirin and NSAIDs inhibit COX-2." | 5.37 | COX-2 expression predicts worse breast cancer prognosis and does not modify the association with aspirin. ( Chen, WY; Colditz, GA; Collins, L; Hankinson, SE; Holmes, MD; Schnitt, SJ; Tamimi, RM, 2011) |
| "In an attempt to increase the antitumor effect of cisplatin (50 mg/m2) and dacarbazine (350 mg/m2), each repeated on days 1 to 3 every 4 weeks in patients with metastatic melanoma, tamoxifen was added to the regimen." | 5.07 | High-dose cisplatin with dacarbazine and tamoxifen in the treatment of metastatic melanoma. ( Buzaid, AC; Durivage, HJ; Murren, JR, 1991) |
| " The present study investigated the effect of an authentic COX inhibitor, aspirin, on regional lymph node metastasis during the development of lung cancer in mice." | 3.80 | Aspirin reduces lung cancer metastasis to regional lymph nodes. ( Amano, H; Hosono, K; Ito, Y; Kitasato, H; Majima, M; Matsui, Y; Ogawa, F; Satoh, Y, 2014) |
| " Therefore, we examined the association between recent (1 year) prediagnostic use of aspirin (COX1/COX2 inhibitor), lymph node involvement at breast cancer diagnosis, and breast cancer-specific mortality." | 3.80 | Recent prediagnostic aspirin use, lymph node involvement, and 5-year mortality in women with stage I-III breast cancer: a nationwide population-based cohort study. ( Barron, TI; Bennett, K; Flahavan, EM; Sharp, L; Visvanathan, K, 2014) |
| "The injection of aspirin on lymph nodes caused necrosis and an increase of apoptosis after 24 hours and after seven days of treatment there was regeneration of the lymph nodes, with intense decrease of necrosis and a great elevation of apoptosis." | 3.78 | Effects of aspirin on mesenteric lymph nodes of rabbits as basis for its use on lymph nodes metastases. ( Batista, RP; Denadai, R; Saad-Hossne, R, 2012) |
| "Pretreatment of aspirin at non-toxic dose 0." | 1.48 | Aspirin suppresses components of lymphangiogenesis and lymphatic vessel remodeling by inhibiting the NF-κB/VCAM-1 pathway in human lymphatic endothelial cells. ( Jantaree, P; Koizumi, K; Lirdprapamongkol, K; Ngiwsara, L; Prangsaengtong, O; Svasti, J, 2018) |
| "Aspirin and NSAIDs inhibit COX-2." | 1.37 | COX-2 expression predicts worse breast cancer prognosis and does not modify the association with aspirin. ( Chen, WY; Colditz, GA; Collins, L; Hankinson, SE; Holmes, MD; Schnitt, SJ; Tamimi, RM, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prangsaengtong, O | 1 |
| Jantaree, P | 1 |
| Lirdprapamongkol, K | 1 |
| Ngiwsara, L | 1 |
| Svasti, J | 1 |
| Koizumi, K | 1 |
| Ogawa, F | 1 |
| Amano, H | 1 |
| Ito, Y | 1 |
| Matsui, Y | 1 |
| Hosono, K | 1 |
| Kitasato, H | 1 |
| Satoh, Y | 1 |
| Majima, M | 1 |
| Ljung, R | 1 |
| Sennerstam, R | 1 |
| Mattsson, F | 1 |
| Auer, G | 1 |
| Lagergren, J | 1 |
| Barron, TI | 1 |
| Flahavan, EM | 1 |
| Sharp, L | 1 |
| Bennett, K | 1 |
| Visvanathan, K | 1 |
| Holmes, MD | 1 |
| Chen, WY | 1 |
| Schnitt, SJ | 1 |
| Collins, L | 1 |
| Colditz, GA | 1 |
| Hankinson, SE | 1 |
| Tamimi, RM | 1 |
| Lee, SH | 1 |
| Shin, SJ | 1 |
| Park, DI | 1 |
| Kim, SE | 1 |
| Hong, SP | 1 |
| Hong, SN | 1 |
| Yang, DH | 1 |
| Lee, BI | 1 |
| Kim, YH | 1 |
| Kim, HS | 1 |
| Yang, SK | 1 |
| Kim, HJ | 2 |
| Kim, SH | 1 |
| Dhillon, PK | 1 |
| Kenfield, SA | 1 |
| Stampfer, MJ | 1 |
| Giovannucci, EL | 1 |
| Chan, JM | 1 |
| Batista, RP | 1 |
| Denadai, R | 1 |
| Saad-Hossne, R | 1 |
| Füessl, HS | 1 |
| Yamamoto, H | 1 |
| Itoh, F | 1 |
| Fukushima, H | 1 |
| Hinoda, Y | 1 |
| Imai, K | 1 |
| Yoshizaki, T | 1 |
| Buzaid, AC | 1 |
| Murren, JR | 1 |
| Durivage, HJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Small Colorectal Polyp Removal Using Cold Endoscopic Mucosal Resection With Hot Endoscopic Mucosal Resection: a Pilot Study[NCT03000868] | 0 participants (Actual) | Interventional | 2016-12-01 | Withdrawn (stopped due to No participants were enrolled.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for aspirin and Lymph Node Metastasis
| Article | Year |
|---|---|
[Expression of pharyngeal- tumor- metastasis related genes and possibility of the gene therapy--Suppressive effects of aspirin on the tumor metastasis].
Topics: Animals; Aspirin; Gene Expression; Genetic Therapy; Herpesvirus 4, Human; Humans; I-kappa B Proteins | 2001 |
1 trial available for aspirin and Lymph Node Metastasis
| Article | Year |
|---|---|
High-dose cisplatin with dacarbazine and tamoxifen in the treatment of metastatic melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Cisplatin; Dacarbazine; Drug E | 1991 |
10 other studies available for aspirin and Lymph Node Metastasis
| Article | Year |
|---|---|
Aspirin suppresses components of lymphangiogenesis and lymphatic vessel remodeling by inhibiting the NF-κB/VCAM-1 pathway in human lymphatic endothelial cells.
Topics: Aspirin; Cell Movement; Cell Proliferation; Endothelial Cells; Humans; Lymphangiogenesis; Lymphatic | 2018 |
Aspirin reduces lung cancer metastasis to regional lymph nodes.
Topics: Animals; Aspirin; Carcinoma, Lewis Lung; Cyclooxygenase Inhibitors; Green Fluorescent Proteins; Lung | 2014 |
Anticoagulant medication at time of needle biopsy for breast cancer in relation to risk of lymph node metastasis.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Biopsy, Needle; Blood Coagulation; Blood Pl | 2014 |
Recent prediagnostic aspirin use, lymph node involvement, and 5-year mortality in women with stage I-III breast cancer: a nationwide population-based cohort study.
Topics: Aged; Aged, 80 and over; Aspirin; Breast Neoplasms; Cohort Studies; Cyclooxygenase Inhibitors; Femal | 2014 |
COX-2 expression predicts worse breast cancer prognosis and does not modify the association with aspirin.
Topics: Adult; Antineoplastic Agents; Aspirin; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breas | 2011 |
[Korean guidelines for colonoscopic polypectomy].
Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Polyps; Colonoscopy; Colorectal N | 2012 |
Aspirin use after a prostate cancer diagnosis and cancer survival in a prospective cohort.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; California; Follow-Up Studies; Humans | 2012 |
Effects of aspirin on mesenteric lymph nodes of rabbits as basis for its use on lymph nodes metastases.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aspirin; Drug Screening Assays, Antitumor; Germinal Cente | 2012 |
[Before polyp removal. To stop or not to stop ASA?].
Topics: Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Polyps; Endoscopy; Ga | 2003 |
Overexpression of cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability.
Topics: Adaptor Proteins, Signal Transducing; Aspirin; Base Pair Mismatch; Carrier Proteins; Cyclooxygenase | 1999 |