aspirin has been researched along with Liver Diseases, Alcoholic in 8 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The degree of liver fibrosis was determined using four validated fibrosis indices and a composite index." | 1.43 | Aspirin use is associated with lower indices of liver fibrosis among adults in the United States. ( Afdhal, N; Feldbrügge, L; Ghaziani, T; Jiang, ZG; Mukamal, KJ; Popov, Y; Robson, SC; Tapper, EB, 2016) |
| " In addition, ibuprofen can be combined with acetaminophen without altering the pharmacokinetic profile." | 1.27 | Pharmacokinetics of ibuprofen. ( Albert, KS; Gernaat, CM, 1984) |
| " Most of the pharmacokinetic parameters derived from these profiles were not significantly different between young subjects, elderly subjects and subjects with alcoholic liver disease." | 1.27 | Pharmacokinetics of aspirin and salicylate in elderly subjects and in patients with alcoholic liver disease. ( Brooks, PM; Roberts, MS; Rumble, RH; Thomas, D; Wanwimolruk, S, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, ZG | 2 |
| Feldbrügge, L | 2 |
| Tapper, EB | 2 |
| Popov, Y | 2 |
| Ghaziani, T | 2 |
| Afdhal, N | 2 |
| Robson, SC | 2 |
| Mukamal, KJ | 2 |
| Lu, Y | 1 |
| Wong, F | 1 |
| Albert, KS | 1 |
| Gernaat, CM | 1 |
| Roberts, MS | 1 |
| Rumble, RH | 1 |
| Wanwimolruk, S | 1 |
| Thomas, D | 1 |
| Brooks, PM | 2 |
| Rainsford, KD | 1 |
| Ford, NL | 1 |
| Watson, HM | 1 |
| Koskinen, LK | 1 |
| Korpela, MM | 1 |
| Lahtela, JT | 1 |
| Laippala, PJ | 1 |
| Pikkarainen, PH | 1 |
| Koivula, TA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-label, Randomized, 3-way Crossover Study to Evaluate the Pharmacokinetics of Investigational Product Ibuprofen Modified-Release Tablets 800 mg Compared to Ibuprofen Tablets 800 mg in Healthy Volunteers[NCT05329454] | Phase 1 | 30 participants (Actual) | Interventional | 2020-12-24 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for aspirin and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
Liver and kidney diseases.
Topics: Acetaminophen; Anemia, Sickle Cell; Animals; Aspirin; Cholestasis; Cysts; Glomerulonephritis, IGA; G | 2002 |
1 trial available for aspirin and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
Effect of acetaldehyde and acetylsalicylic acid on HbA1c chromatography in the FPLC method with Mono S cation exchanger.
Topics: Acetaldehyde; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cation Exchange Resins; Chrom | 1998 |
6 other studies available for aspirin and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
Aspirin use is associated with lower indices of liver fibrosis among adults in the United States.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Sectional Studies; Female; Hepatitis, | 2016 |
Letter: would aspirin alleviate fibrosis in alcoholic liver disease?
Topics: Aspirin; Fibrosis; Humans; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic | 2016 |
Letter: would aspirin alleviate fibrosis in alcoholic liver disease? Authors' reply.
Topics: Aspirin; Humans; Liver Diseases, Alcoholic | 2016 |
Pharmacokinetics of ibuprofen.
Topics: Acetaminophen; Adult; Age Factors; Aged; Arthritis, Rheumatoid; Aspirin; Biological Availability; Ch | 1984 |
Pharmacokinetics of aspirin and salicylate in elderly subjects and in patients with alcoholic liver disease.
Topics: Adult; Aged; Aging; Aspirin; Blood Proteins; Humans; Kinetics; Liver Diseases, Alcoholic; Male; Midd | 1983 |
Plasma aspirin esterases in normal individuals, patients with alcoholic liver disease and rheumatoid arthritis: characterization and the importance of the enzymic components.
Topics: Acetylation; Arthritis, Rheumatoid; Aspirin; Calcium; Carboxylic Ester Hydrolases; Humans; Liver Dis | 1980 |