aspirin has been researched along with Leukemia L 1210 in 4 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ibuprofen also did not increase brequinar's antitumor potency." | 1.28 | Effects of plasma protein binding displacement on the pharmacokinetics, tissue and tumor concentrations and efficacy of brequinar, a highly protein-bound antitumor agent. ( Aungst, BJ; Blake, JA; Dusak, BA; Rogers, NJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tovey, MG | 1 |
| Gresser, I | 1 |
| Rochette-Egly, C | 1 |
| Begon-Lours-Guymarho, J | 1 |
| Bandu, MT | 1 |
| Maury, C | 1 |
| Brideau, RJ | 1 |
| Stringfellow, DA | 1 |
| Aungst, BJ | 1 |
| Blake, JA | 1 |
| Rogers, NJ | 1 |
| Dusak, BA | 1 |
| Goldman, ID | 1 |
4 other studies available for aspirin and Leukemia L 1210
| Article | Year |
|---|---|
Indomethacin and aspirin do not inhibit the antiviral or anti-proliferative actions of interferon.
Topics: Animals; Aspirin; Cell Division; Cell Line; Encephalomyocarditis virus; Indomethacin; Interferons; L | 1982 |
Antiproliferative action of interferon on murine L1210 cells: interrelationship with prostaglandins.
Topics: Animals; Aspirin; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Growth Inhibitors; Indo | 1983 |
Effects of plasma protein binding displacement on the pharmacokinetics, tissue and tumor concentrations and efficacy of brequinar, a highly protein-bound antitumor agent.
Topics: Animals; Antineoplastic Agents; Aspirin; Biphenyl Compounds; Blood Proteins; Dose-Response Relations | 1990 |
The characteristics of the membrane transport of amethopterin and the naturally occurring folates.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspirin; Azides; Biological Transport, Active; | 1971 |