aspirin has been researched along with Leprosy in 12 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six male patients of lepromatous leprosy with erythema nodosum leprosum reaction (ENL) reactions diagnosed clinically and by slit skin smear were treated with aspirin and clofazimine." | 7.83 | A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases. ( Sharma, PK; Singh, DK, 2016) |
| "Six male patients of lepromatous leprosy with erythema nodosum leprosum reaction (ENL) reactions diagnosed clinically and by slit skin smear were treated with aspirin and clofazimine." | 3.83 | A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases. ( Sharma, PK; Singh, DK, 2016) |
| "Pharmacokinetics of aspirin and chloramphenicol was studied in 16 normal and 16 patients suffering from leprosy." | 3.67 | Pharmacokinetics of aspirin and chloramphenicol in normal and leprotic patients before and after dapsone therapy. ( Bakaya, V; Garg, SK; Kaur, S; Kumar, B; Lal, R; Shukla, VK, 1988) |
| "Leprosy is a rare cause of neuropathy in Europeans." | 1.35 | [Sensory-motor neuropathy: a slow and misleading case of leprosy]. ( Andre, P; Camu, W; Flageul, B; Gabelle, A; Vallat, JM, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, PK | 1 |
| Singh, DK | 1 |
| Montone, KT | 1 |
| Gabelle, A | 1 |
| Vallat, JM | 1 |
| Flageul, B | 1 |
| Andre, P | 1 |
| Camu, W | 1 |
| Sheskin, J | 1 |
| Ross, WF | 1 |
| Pearson, JM | 1 |
| Pfaltzgraff, RE | 1 |
| Klenerman, P | 1 |
| Garg, SK | 1 |
| Kumar, B | 1 |
| Shukla, VK | 1 |
| Bakaya, V | 1 |
| Lal, R | 1 |
| Kaur, S | 1 |
| Segasothy, M | 1 |
| Muhaya, HM | 1 |
| Musa, A | 1 |
| Rajagopalan, K | 1 |
| Lim, KJ | 1 |
| Fatimah, Y | 1 |
| Kamal, A | 1 |
| Ahmad, KS | 1 |
| Tandon, GS | 1 |
| Shukla, RC | 1 |
| Benjamin, S | 1 |
| Karat, AB | 1 |
| Thomas, G | 1 |
| Rao, PS | 1 |
| Iyer, CG | 1 |
| Languillon, J | 1 |
| Ramanujam, K | 1 |
| Tarabini-Castellani, G | 1 |
| De las Aguas, JT | 1 |
| Bechelli, LM | 1 |
| Uemura, K | 1 |
| Martinez Dominguez, V | 1 |
| Sundaresan, T | 1 |
2 reviews available for aspirin and Leprosy
| Article | Year |
|---|---|
The molecular genetics of inflammatory, autoimmune, and infectious diseases of the sinonasal tract: a review.
Topics: Aspirin; Autoimmune Diseases; Churg-Strauss Syndrome; Granulomatosis with Polyangiitis; Humans; Infe | 2014 |
Prostaglandins and leprosy. A role for aspirin?
Topics: Aspirin; Humans; Leprosy; Prostaglandins | 1989 |
4 trials available for aspirin and Leprosy
| Article | Year |
|---|---|
[Therapeutic experience on the effect of thalidomidomide on lepra reaction].
Topics: Aspirin; Climate; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Israel; Lepro | 1975 |
Effect of bradykinin and its antagonists on superficial and deep pain in human subjects and dogs.
Topics: Acetylcholine; Animals; Arachnida; Aspirin; Blister; Bradykinin; Clinical Trials as Topic; Codeine; | 1966 |
Indomethacin in the management of erythema nodosum leprosum--a double-blind controlled trial.
Topics: Adolescent; Adult; Aspirin; Chloroquine; Clinical Trials as Topic; Erythema Nodosum; Humans; Indomet | 1969 |
WHO co-ordinated short-term double-blind trial with thalidomide in the treatment of acute lepra reactions in male lepromatous patients.
Topics: Acute Disease; Adolescent; Adult; Aspirin; Clinical Trials as Topic; Humans; Leprosy; Male; Middle A | 1971 |
6 other studies available for aspirin and Leprosy
| Article | Year |
|---|---|
A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clofazimine; Dapsone; Drug Therapy, Combina | 2016 |
[Sensory-motor neuropathy: a slow and misleading case of leprosy].
Topics: Adrenal Cortex Hormones; Aged; Aspirin; Clofazimine; Dapsone; Diagnosis, Differential; Female; Human | 2008 |
The recognition and management of nerve damage under field conditions.
Topics: Aspirin; Humans; Leprosy; Nervous System Diseases; Prednisolone | 1975 |
The management of reaction in leprosy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Aspirin; Benzenesulfonates; Chloroquine | 1989 |
Pharmacokinetics of aspirin and chloramphenicol in normal and leprotic patients before and after dapsone therapy.
Topics: Adult; Aspirin; Chloramphenicol; Dapsone; Drug Interactions; Female; Half-Life; Humans; Leprosy; Mal | 1988 |
Analgesic use by leprosy patients.
Topics: Acetaminophen; Adult; Aged; Analgesics; Aspirin; Female; Humans; Kidney Papillary Necrosis; Leprosy; | 1986 |