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aspirin and Leprosy

aspirin has been researched along with Leprosy in 12 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.

Research Excerpts

ExcerptRelevanceReference
"Six male patients of lepromatous leprosy with erythema nodosum leprosum reaction (ENL) reactions diagnosed clinically and by slit skin smear were treated with aspirin and clofazimine."7.83A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases. ( Sharma, PK; Singh, DK, 2016)
"Six male patients of lepromatous leprosy with erythema nodosum leprosum reaction (ENL) reactions diagnosed clinically and by slit skin smear were treated with aspirin and clofazimine."3.83A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases. ( Sharma, PK; Singh, DK, 2016)
"Pharmacokinetics of aspirin and chloramphenicol was studied in 16 normal and 16 patients suffering from leprosy."3.67Pharmacokinetics of aspirin and chloramphenicol in normal and leprotic patients before and after dapsone therapy. ( Bakaya, V; Garg, SK; Kaur, S; Kumar, B; Lal, R; Shukla, VK, 1988)
"Leprosy is a rare cause of neuropathy in Europeans."1.35[Sensory-motor neuropathy: a slow and misleading case of leprosy]. ( Andre, P; Camu, W; Flageul, B; Gabelle, A; Vallat, JM, 2008)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharma, PK1
Singh, DK1
Montone, KT1
Gabelle, A1
Vallat, JM1
Flageul, B1
Andre, P1
Camu, W1
Sheskin, J1
Ross, WF1
Pearson, JM1
Pfaltzgraff, RE1
Klenerman, P1
Garg, SK1
Kumar, B1
Shukla, VK1
Bakaya, V1
Lal, R1
Kaur, S1
Segasothy, M1
Muhaya, HM1
Musa, A1
Rajagopalan, K1
Lim, KJ1
Fatimah, Y1
Kamal, A1
Ahmad, KS1
Tandon, GS1
Shukla, RC1
Benjamin, S1
Karat, AB1
Thomas, G1
Rao, PS1
Iyer, CG1
Languillon, J1
Ramanujam, K1
Tarabini-Castellani, G1
De las Aguas, JT1
Bechelli, LM1
Uemura, K1
Martinez Dominguez, V1
Sundaresan, T1

Reviews

2 reviews available for aspirin and Leprosy

ArticleYear
The molecular genetics of inflammatory, autoimmune, and infectious diseases of the sinonasal tract: a review.
    Archives of pathology & laboratory medicine, 2014, Volume: 138, Issue:6

    Topics: Aspirin; Autoimmune Diseases; Churg-Strauss Syndrome; Granulomatosis with Polyangiitis; Humans; Infe

2014
Prostaglandins and leprosy. A role for aspirin?
    Leprosy review, 1989, Volume: 60, Issue:1

    Topics: Aspirin; Humans; Leprosy; Prostaglandins

1989

Trials

4 trials available for aspirin and Leprosy

ArticleYear
[Therapeutic experience on the effect of thalidomidomide on lepra reaction].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1975, Volume: 26, Issue:1

    Topics: Aspirin; Climate; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Israel; Lepro

1975
Effect of bradykinin and its antagonists on superficial and deep pain in human subjects and dogs.
    Indian journal of physiology and pharmacology, 1966, Volume: 10, Issue:3

    Topics: Acetylcholine; Animals; Arachnida; Aspirin; Blister; Bradykinin; Clinical Trials as Topic; Codeine;

1966
Indomethacin in the management of erythema nodosum leprosum--a double-blind controlled trial.
    Leprosy review, 1969, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Aspirin; Chloroquine; Clinical Trials as Topic; Erythema Nodosum; Humans; Indomet

1969
WHO co-ordinated short-term double-blind trial with thalidomide in the treatment of acute lepra reactions in male lepromatous patients.
    Bulletin of the World Health Organization, 1971, Volume: 45, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aspirin; Clinical Trials as Topic; Humans; Leprosy; Male; Middle A

1971

Other Studies

6 other studies available for aspirin and Leprosy

ArticleYear
A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases.
    Indian journal of leprosy, 2016, Volume: 87, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clofazimine; Dapsone; Drug Therapy, Combina

2016
[Sensory-motor neuropathy: a slow and misleading case of leprosy].
    Revue neurologique, 2008, Volume: 164, Issue:11

    Topics: Adrenal Cortex Hormones; Aged; Aspirin; Clofazimine; Dapsone; Diagnosis, Differential; Female; Human

2008
The recognition and management of nerve damage under field conditions.
    Leprosy review, 1975, Volume: 46, Issue:3

    Topics: Aspirin; Humans; Leprosy; Nervous System Diseases; Prednisolone

1975
The management of reaction in leprosy.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1989, Volume: 57, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Aspirin; Benzenesulfonates; Chloroquine

1989
Pharmacokinetics of aspirin and chloramphenicol in normal and leprotic patients before and after dapsone therapy.
    International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:4

    Topics: Adult; Aspirin; Chloramphenicol; Dapsone; Drug Interactions; Female; Half-Life; Humans; Leprosy; Mal

1988
Analgesic use by leprosy patients.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1986, Volume: 54, Issue:3

    Topics: Acetaminophen; Adult; Aged; Analgesics; Aspirin; Female; Humans; Kidney Papillary Necrosis; Leprosy;

1986