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aspirin and Intraocular Pressure

aspirin has been researched along with Intraocular Pressure in 38 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"The effects of aspirin, cyclophosphamide, and dexamethasone on secondary herpes simplex uveitis were studied in rabbits."7.66Aspirin, cyclophosphamide, and dexamethasone effects on experimental secondary herpes simplex uveitis. ( Dennis, RF; Oh, JO, 1979)
"We studied, using anesthetized albino rabbits, whether polymodal receptors are responsible for rise in the intraocular pressure (IOP) caused by algesic substances, and also whether substance P (SP) is involved in this phenomenon."3.68Implication of polymodal receptor activities in intraocular pressure elevation by neurogenic inflammation. ( Awaya, S; Kumazawa, T; Mizumura, K; Yokoyama, K, 1990)
"Aqueous protein concentration, degree of miosis, and intraocular pressure were evaluated in dogs given aspirin, then subjected to aqueous paracentesis and reverse cyclodialysis."3.66Effect of aspirin on aqueous protein values in the dog. ( Brightman, AH; Helper, LC; Hoffman, WE, 1981)
"The effects of aspirin, cyclophosphamide, and dexamethasone on secondary herpes simplex uveitis were studied in rabbits."3.66Aspirin, cyclophosphamide, and dexamethasone effects on experimental secondary herpes simplex uveitis. ( Dennis, RF; Oh, JO, 1979)
"Aspirin was associated with a significantly higher risk of hyphaema (P=0."1.34The effect of aspirin and warfarin therapy in trabeculectomy. ( Chadha, V; Chakrabarti, S; Cobb, CJ; Sanders, R, 2007)
"We report a case of unilateral central retinal vein occlusion resulting from essential thrombocythemia, a rare myeloproliferative disorder with abnormally increased platelet count."1.29Essential thrombocythemia and central retinal vein occlusion with neovascular glaucoma. ( Townsend-Pico, W; Yoshizumi, MO, 1996)
"Both indomethacin and aspirin were shown to prodcue a significant reduction in the acute ocular hypertension which can be expected to follow 6 hours after routine cataract surgery."1.26Prevention of postoperative ocular hypertension by prostaglandin inhibitors. ( Rich, WJ, 1977)
"Pretreatment with aspirin plus iridectomy virtually eliminates the elevation of intraocular pressure consequent to paracentesis."1.26Increased pressure after paracentesis of the rabbit eye is completely accounted for by prostaglandin synthesis and release plus pupillary block. ( Al-Ghadyan, A; Mead, A; Sears, M, 1979)
"Aspirin pretreatment before third ventricle instillation of arachidonic acid blocked the increases of intraocular pressure and temperature."1.26Increased intraocular pressure after third ventricle injections of prostaglandin E1 and arachidonic acid. ( Becker, B; Krupin, T; Oestrich, C; Podos, SM, 1976)
"Pretreatment with aspirin or indomethacin virtually abolished the increase in intraocular pressure and elevation of prostaglandin-like activity in the aqueous humor following a 20 mul burn."1.25Prostaglandin-like activity in the aqueous humor following alkali burns. ( Paterson, CA; Pfister, RR, 1975)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199022 (57.89)18.7374
1990's6 (15.79)18.2507
2000's6 (15.79)29.6817
2010's4 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Golan, S1
Levkovitch-Verbin, H1
Shemesh, G1
Kurtz, S1
Khawaja, AP1
Chan, MP1
Broadway, DC1
Garway-Heath, DF1
Luben, R1
Yip, JL1
Hayat, S1
Wareham, NJ1
Khaw, KT1
Foster, PJ1
Celebi, AR1
Kilavuzoglu, AE1
Altiparmak, UE1
Cosar, CB1
Elgin, U1
Sen, E1
Teke, MY1
Tirhis, H1
Ozturk, F1
Goff, MJ1
Kerrison, JB1
Soares, AS1
Artes, PH1
Andreou, P1
Leblanc, RP1
Chauhan, BC1
Nicolela, MT1
Hakim, SA1
Cobb, CJ1
Chakrabarti, S1
Chadha, V1
Sanders, R1
Jonas, JB1
De Castro, DK1
Punjabi, OS1
Bostrom, AG1
Stamper, RL1
Lietman, TM1
Ray, K1
Lin, SC1
Haddad, R2
Grabner, G2
Strasser, G1
Braun, F2
Wizemann, A1
Ebinger, G1
Krey, H1
Wizemann, V1
Brightman, AH1
Helper, LC1
Hoffman, WE1
Yoshizumi, MO1
Townsend-Pico, W1
Feke, GT1
Yoshida, A1
Ogasawara, H1
Konno, S1
Goger, DG1
Buzney, SM1
McMeel, JW1
Leo-Kottler, B1
Klein, R1
Berg, PA1
Zrenner, E1
Lindén, C1
Alm, A1
Marsettio, M1
Siverio, CE1
Oh, JO2
Dennis, RF1
Paterson, CA1
Pfister, RR1
Rich, WJ1
Eakins, KE1
Al-Ghadyan, A1
Mead, A1
Sears, M1
Colasanti, BK1
Barany, EH1
Zimmerman, TJ1
Binder, PS1
Abel, R1
Kaufman, HE1
Krupin, T2
Bass, J1
Oestrich, C2
Podos, SM4
Becker, B3
Zedler, G1
Obstbaum, SA1
Kass, MA2
Neufeld, AH1
Sears, ML1
Mancino, M1
Ohia, E1
Kulkarni, P1
Yokoyama, K1
Awaya, S1
Mizumura, K1
Kumazawa, T1
Green, K1
Nye, RA1
Nelson, E1
Cheeks, L1
Plocher, DW1
Sandford-Smith, JH1
Béchetoille, A1
Leprêtre, C1
Guillaumat, L1

Reviews

1 review available for aspirin and Intraocular Pressure

ArticleYear
Prostaglandin and non-prostaglandin mediated breeakdown of the blood-aqueous barrier.
    Experimental eye research, 1977, Volume: 25 Suppl

    Topics: Animals; Aqueous Humor; Aspirin; Blood; Capillary Permeability; Eye; Humans; Indomethacin; Intraocul

1977

Trials

5 trials available for aspirin and Intraocular Pressure

ArticleYear
Anterior chamber bleeding after laser peripheral iridotomy.
    JAMA ophthalmology, 2013, Volume: 131, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Anticoagulants; Aspirin; Clopidogrel; Eye Color; F

2013
Retinal blood flow increases following short-term aspirin usage in type I diabetics with no or minimal retinopathy.
    Ophthalmic research, 1996, Volume: 28, Issue:2

    Topics: Adult; Aspirin; Blood Flow Velocity; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetic Retinop

1996
Acetylsalicylic acid does not reduce the intraocular pressure variation in ocular hypertension or glaucoma.
    Experimental eye research, 2000, Volume: 70, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method

2000
Aspirin and the intraocular pressure rise following aphakic penetrating keratoplasty: a negative report.
    Annals of ophthalmology, 1976, Volume: 8, Issue:5

    Topics: Aged; Aspirin; Cataract Extraction; Clinical Trials as Topic; Corneal Transplantation; Humans; Intra

1976
[Do parenterally administered anti-prostaglandins have an action on the ocular pressure?].
    Bulletin des societes d'ophtalmologie de France, 1972, Volume: 72, Issue:3

    Topics: Acetazolamide; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Intraocular Pressure; Placeb

1972

Other Studies

32 other studies available for aspirin and Intraocular Pressure

ArticleYear
Systemic medication and intraocular pressure in a British population: the EPIC-Norfolk Eye Study.
    Ophthalmology, 2014, Volume: 121, Issue:8

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aspirin; Biguanides; Blood Pressure; Body Mass

2014
Corneal Biomechanical Properties in Aspirin Users.
    Ophthalmic research, 2016, Volume: 55, Issue:4

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomechanical Phenomena; Case-Control Studie

2016
Microtrauma-induced recurrent hyphema and secondary glaucoma associated with chronic acetylsalicylic acid use.
    International ophthalmology, 2012, Volume: 32, Issue:1

    Topics: Administration, Oral; Adult; Angina Pectoris; Antihypertensive Agents; Aspirin; Diagnosis, Different

2012
Bilateral simultaneous anterior ischemic optic neuropathy in a young, healthy man.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:11

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Brimonidine Tartra

2003
Factors associated with optic disc hemorrhages in glaucoma.
    Ophthalmology, 2004, Volume: 111, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cohort Studies; Cyclooxygenase Inhibitors; Diabetes Complic

2004
Aspirin inhibits oculo-tensin and prevents rise of eye tension.
    Indian journal of ophthalmology, 1971, Volume: 19, Issue:4

    Topics: Animals; Aspirin; Case-Control Studies; Cats; Intraocular Pressure; Platelet Aggregation Inhibitors

1971
The effect of aspirin and warfarin therapy in trabeculectomy.
    Eye (London, England), 2007, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Antihypertensive Agents; Aspirin; Blood

2007
Effect of statin drugs and aspirin on open-angle glaucoma progression.
    Clinical & experimental ophthalmology, 2007, Volume: 35, Issue:6

    Topics: Aspirin; Disease Progression; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Hydroxymethyl

2007
Effect of statin drugs and aspirin on progression in open-angle glaucoma suspects using confocal scanning laser ophthalmoscopy.
    Clinical & experimental ophthalmology, 2007, Volume: 35, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Child; Disease Progression; Drug Therapy, Combi

2007
Mediation of the ocular response to cyclocryocoagulation.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1981, Volume: 216, Issue:3

    Topics: Animals; Aspirin; Ciliary Body; Cryosurgery; Female; Immunoglobulin G; Intraocular Pressure; Male; N

1981
Biphasic action of prostacyclin on intraocular pressure.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1982, Volume: 184, Issue:4

    Topics: Animals; Aspirin; Choroid; Dose-Response Relationship, Drug; Epoprostenol; Fluorescein Angiography;

1982
Effect of aspirin on aqueous protein values in the dog.
    Journal of the American Veterinary Medical Association, 1981, Mar-15, Volume: 178, Issue:6

    Topics: Animals; Aqueous Humor; Aspirin; Blood Proteins; Dogs; Intraocular Pressure; Ophthalmologic Surgical

1981
Essential thrombocythemia and central retinal vein occlusion with neovascular glaucoma.
    American journal of ophthalmology, 1996, Volume: 121, Issue:6

    Topics: Adrenergic beta-Antagonists; Antisickling Agents; Aspirin; Bone Marrow; Fluorescein Angiography; Fun

1996
Ocular symptoms in association with antiphospholipid antibodies.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1998, Volume: 236, Issue:9

    Topics: Adolescent; Adult; Aged; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Aspirin; Drug Ther

1998
Effect of aspirin and dexamethasone on intraocular pressure in primary uveitis produced by Herpes simplex virus.
    American journal of ophthalmology, 1976, Volume: 81, Issue:5

    Topics: Animals; Aspirin; Dexamethasone; Eye; Intraocular Pressure; Keratitis, Dendritic; Male; Ophthalmosco

1976
Aspirin, cyclophosphamide, and dexamethasone effects on experimental secondary herpes simplex uveitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1979, Volume: 97, Issue:11

    Topics: Animals; Aspirin; Cyclophosphamide; Dexamethasone; Herpes Simplex; Intraocular Pressure; Male; Rabbi

1979
Prostaglandin-like activity in the aqueous humor following alkali burns.
    Investigative ophthalmology, 1975, Volume: 14, Issue:3

    Topics: Alkalies; Animals; Aqueous Humor; Aspirin; Blood Pressure; Burns, Chemical; Hydrogen-Ion Concentrati

1975
Prevention of postoperative ocular hypertension by prostaglandin inhibitors.
    Transactions of the ophthalmological societies of the United Kingdom, 1977, Volume: 97, Issue:2

    Topics: Aspirin; Cataract Extraction; Depression, Chemical; Humans; Indomethacin; Intraocular Pressure; Post

1977
[Inhibition of secondary increase of intraocular pressure following cyclokryocoagulation (author's transl)].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, May-07, Volume: 210, Issue:3

    Topics: Animals; Aspirin; Ciliary Body; Cold Temperature; Depression, Chemical; Female; Intraocular Pressure

1979
Increased pressure after paracentesis of the rabbit eye is completely accounted for by prostaglandin synthesis and release plus pupillary block.
    Investigative ophthalmology & visual science, 1979, Volume: 18, Issue:4

    Topics: Animals; Aqueous Humor; Aspirin; Eye Proteins; Hyperemia; Intraocular Pressure; Iris; Prostaglandins

1979
Reduction by indomethacin of the degeneration increase in outflow facility after superior cervical ganglionectomy in the rabbit.
    Investigative ophthalmology & visual science, 1978, Volume: 17, Issue:8

    Topics: Animals; Aqueous Humor; Aspirin; Eye; Ganglia, Autonomic; Indomethacin; Intraocular Pressure; Male;

1978
The effect of hyperthermia on aqueous humor dynamics in rabbits.
    American journal of ophthalmology, 1977, Volume: 83, Issue:4

    Topics: Animals; Aqueous Humor; Aspirin; Blood Pressure; Fever; Intraocular Pressure; Male; Optic Nerve; Rab

1977
[Indications and contraindications for analgesics in certain organic diseases and dispositions].
    Stomatologie der DDR, 1976, Volume: 26, Issue:4

    Topics: Analgesics; Aspirin; Drug Hypersensitivity; Humans; Intraocular Pressure; Kidney; Laryngeal Edema; P

1976
Ocular compression and noncorticosteroidal anti-inflammatory agents.
    American journal of ophthalmology, 1975, Volume: 79, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Conjunctiva; Eye Diseases; Humans; Hyperemia; Indomethac

1975
Systemic aspirin and indomethacin do not prevent the response of the monkey eye to trauma.
    Investigative ophthalmology, 1975, Volume: 14, Issue:8

    Topics: Animals; Aqueous Humor; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Endotoxins; Ey

1975
Increased intraocular pressure after third ventricle injections of prostaglandin E1 and arachidonic acid.
    American journal of ophthalmology, 1976, Volume: 81, Issue:3

    Topics: Animals; Arachidonic Acids; Aspirin; Cerebral Ventricles; Dose-Response Relationship, Drug; Injectio

1976
A comparative study between cod liver oil and liquid lard intake on intraocular pressure on rabbits.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 45, Issue:3

    Topics: Administration, Topical; Animals; Aqueous Humor; Aspirin; Cod Liver Oil; Dietary Fats; Flurbiprofen;

1992
Implication of polymodal receptor activities in intraocular pressure elevation by neurogenic inflammation.
    Japanese journal of ophthalmology, 1990, Volume: 34, Issue:2

    Topics: Animals; Anterior Chamber; Aspirin; Bradykinin; Female; Glucose; Intraocular Pressure; Male; Neuriti

1990
Role of eicosanoids in the ocular response to intracameral hydrogen peroxide.
    Lens and eye toxicity research, 1990, Volume: 7, Issue:1

    Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Cili

1990
Ophthalmic response to inverted posture.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:6

    Topics: Adult; Aspirin; Conjunctival Diseases; Esotropia; Eye; Eye Diseases; Hemorrhage; Humans; Intraocular

1985
Prostaglandin synthesis, inhibition, and intraocular pressure.
    Investigative ophthalmology, 1973, Volume: 12, Issue:6

    Topics: Animals; Aqueous Humor; Arachidonic Acids; Ascorbic Acid; Aspirin; Dose-Response Relationship, Drug;

1973
Transient myopia after aspirin.
    The British journal of ophthalmology, 1974, Volume: 58, Issue:7

    Topics: Adult; Anterior Chamber; Anthropometry; Aspirin; Fundus Oculi; Humans; Intraocular Pressure; Lens, C

1974