Page last updated: 2024-10-23

aspirin and Intestinal Obstruction

aspirin has been researched along with Intestinal Obstruction in 13 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Intestinal Obstruction: Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.

Research Excerpts

ExcerptRelevanceReference
"Randomized patients with available aspirin dosing information in COGENT (N = 3,752) were divided into "low-dose" (≤ 100 mg) and "high-dose" (>100 mg) aspirin groups."2.82Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Hsieh, WH; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; Schnitzer, TJ; Shook, TL; Vaduganathan, M, 2016)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's3 (23.08)18.2507
2000's2 (15.38)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
García-Romera, Á1
Soto-Darias, I1
González-Hernández, S1
González-Delgado, C1
Bravo-Gutiérrez, A1
Vaduganathan, M1
Bhatt, DL1
Cryer, BL1
Liu, Y1
Hsieh, WH1
Doros, G1
Cohen, M1
Lanas, A1
Schnitzer, TJ1
Shook, TL1
Lapuerta, P1
Goldsmith, MA1
Laine, L1
Cannon, CP1
Schmidtko, J1
Truninger, K1
Gugger, M1
Cottagnoud, P1
Stucki, A1
Pilgrim, S1
Velchuru, V1
Waters, G1
Tsiamis, A1
Lal, R1
Kugelmeier, J1
Egloff, L1
Halla, JT1
Fallahi, S1
Hardin, JG1
Robinson, MH1
Wheatley, T1
Leach, IH1
Catheline, JM1
Guiberteau/Canfrere, V1
Zarka, O1
Le Borgne, J1
Lehur, PA1
Kehrer, G1
Bosseckert, H1
Koppe, P1
Lutz, B1
Will, U1
Zinsser, E1
Baekelandt, M1
Vansteenberge, R1
Van der Spek, P1
D'Haenens, P1
Rollier, A1
Stockx, L1
Bourhis, F1
Riard, P1
Rolachon, A1
Danel, V1
Hostein, J1
Fournet, J1
Goldman, CD1
Rudloff, MA1
Ternberg, JL1
Stafford, ES1
Zuidema, GD1
Cameron, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blind, Double-Dummy, Parallel Group, Phase 3 Efficacy and Safety Study of CGT-2168 Compared With Clopidogrel to Reduce Upper Gastrointestinal Events Including Bleeding and Symptomatic Ulcer Disease[NCT00557921]Phase 35,000 participants (Anticipated)Interventional2007-12-31Terminated (stopped due to Terminated by Sponsor)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for aspirin and Intestinal Obstruction

ArticleYear
[Pulmonary embolism in surgical patients (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1980, Dec-16, Volume: 69, Issue:50

    Topics: Age Factors; Aged; Anticoagulants; Aspirin; Bed Rest; Dextrans; Female; Heart Failure; Humans; Intes

1980
Nonsteroidal antiinflammatory drug-induced colonic stricture. An unusual cause of large bowel obstruction and perforation.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Colonic Diseases; Delayed-Ac

1995
Rectal stenosis following the use of suppositories containing paracetamol and acetylsalicylic acid.
    Gastrointestinal radiology, 1990,Spring, Volume: 15, Issue:2

    Topics: Acetaminophen; Aged; Aspirin; Female; Humans; Intestinal Obstruction; Rectal Diseases; Suppositories

1990

Trials

1 trial available for aspirin and Intestinal Obstruction

ArticleYear
Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy.
    Journal of the American College of Cardiology, 2016, Apr-12, Volume: 67, Issue:14

    Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyspepsia;

2016

Other Studies

9 other studies available for aspirin and Intestinal Obstruction

ArticleYear
Small bowel obstruction secondary to enteroenteric fistula: An uncommon complication in chronic NSAID users.
    Cirugia espanola, 2020, Volume: 98, Issue:4

    Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Female; Huma

2020
[What is your diagnosis? Diaphragma disease].
    Praxis, 2008, Feb-06, Volume: 97, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Diseases; Diagnosis, Differential; Diclofe

2008
Diaphragm disease and small bowel enteropathy due to nonsteroidal anti-inflammatory drugs: a surgical perspective.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2011, Volume: 13, Issue:4

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Constriction, Pathologic; Diaphragm; Diclofe

2011
Acute and chronic salicylate intoxication in a patient with gastric outlet obstruction.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:9

    Topics: Adult; Arthritis, Rheumatoid; Aspirin; Female; Humans; Intestinal Obstruction; Tablets, Enteric-Coat

1981
[Rectal stenosis following prolonged use of suppositories of acetylsalicylic acid and paracetamol. Correction by perineal approach].
    Annales de chirurgie, 1995, Volume: 49, Issue:6

    Topics: Acetaminophen; Aged; Aspirin; Female; Humans; Intestinal Obstruction; Migraine Disorders; Perineum;

1995
Unusual negative side effects of non-steroidal anti-inflammatory drugs in the proximal colon.
    Zeitschrift fur Gastroenterologie, 2000, Volume: 38, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Diseases; Diagnos

2000
[An uncommon etiology of occlusive syndrome: Propofan poisoning].
    Gastroenterologie clinique et biologique, 1989, Volume: 13, Issue:6-7

    Topics: Acetaminophen; Adult; Aspirin; Chlorpheniramine; Dextropropoxyphene; Drug Combinations; Humans; Inte

1989
Cytoprotective agents in experimental small bowel volvulus.
    Journal of pediatric surgery, 1987, Volume: 22, Issue:3

    Topics: Alprostadil; Animals; Aspirin; Ephedrine; Ibuprofen; Indomethacin; Intestinal Obstruction; Intestine

1987
Unusual causes of occult bleeding from the gastrointestinal tract.
    American journal of surgery, 1970, Volume: 119, Issue:2

    Topics: Adolescent; Adult; Aged; Anemia; Aspirin; Child; Diagnosis, Differential; Esophagitis, Peptic; Femal

1970