aspirin has been researched along with Intestinal Diseases in 55 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied 30 patients with postsurgical ulcer and aspirin abuse." | 7.70 | Intractable upper gastrointestinal ulceration due to aspirin in patients who have undergone surgery for peptic ulcer. ( Hirschowitz, BI; Lanas, A, 1998) |
| "Indomethacin produced true ulcers; the lesions penetrated into the muscularis mucosae of the antrum of refed rats and into the intestine of both refed and conventionally fed rats." | 7.67 | Sodium-salicylate in contrast with acetylsalicylic acid prevents gastric antral and intestinal ulcers produced by indomethacin in the refed rat. ( Ezer, E, 1985) |
| "The use of low-dose aspirin (LDA) is well known to be associated with an increased risk of serious upper gastrointestinal complications, such as peptic ulceration and bleeding." | 4.91 | Small bowel injury in low-dose aspirin users. ( Endo, H; Higurashi, T; Kato, T; Nakajima, A; Ohkubo, H; Sakai, E; Umezawa, S, 2015) |
| "We studied 30 patients with postsurgical ulcer and aspirin abuse." | 3.70 | Intractable upper gastrointestinal ulceration due to aspirin in patients who have undergone surgery for peptic ulcer. ( Hirschowitz, BI; Lanas, A, 1998) |
| "Indomethacin produced true ulcers; the lesions penetrated into the muscularis mucosae of the antrum of refed rats and into the intestine of both refed and conventionally fed rats." | 3.67 | Sodium-salicylate in contrast with acetylsalicylic acid prevents gastric antral and intestinal ulcers produced by indomethacin in the refed rat. ( Ezer, E, 1985) |
| " However its potential adverse effects on the small and large intestine are less well known and under- researched." | 2.52 | Aspirin Induced Adverse Effects on the Small and Large Intestine. ( Bjarnason, I; Pavlidis, P, 2015) |
| " It is necessary to be aware of not only gastro-duodenal ulcers but also lower intestinal lesions with long-term use of low-dose aspirin." | 2.46 | [Diagnosis and therapy of intestinal mucosal injury due to low-dose aspirin]. ( Osada, T; Shibuya, T; Watanabe, S, 2010) |
| " Acute or chronic use of non-salicylate NSAIDs increases the risk for ischemic colitis and flare-ups of inflammatory bowel disease." | 2.42 | [Gastrointestinal complications related to NSAIDs]. ( Beaugerie, L; Thiéfin, G, 2004) |
| "These results suggest that the recurrence of NSAID-induced small bowel injury was not frequent in the presence of conservative treatment." | 1.42 | Long-Term Outcomes of NSAID-Induced Small Intestinal Injury Assessed by Capsule Endoscopy in Korea: A Nationwide Multicenter Retrospective Study. ( Chang, DK; Cheon, JH; Choi, MG; Chun, HJ; Jang, BI; Jeen, YT; Jeon, SR; Jeon, SW; Kim, JH; Kim, JO; Kim, JS; Lee, KJ; Lim, YJ; Moon, JS; Park, CH; Shim, KN; Song, EM; Song, HJ; Ye, BD, 2015) |
| "Once gastrointestinal hemorrhage has occurred, several studies have indicated the need to implement simpler prognostic scales than those used today." | 1.38 | [Gastrointestinal bleeding associated with NSAIDs, antiplatelet therapy and anticoagulant agent]. ( Lanas, A, 2012) |
| "Anticoagulation therapy and factor VIII deficiency were found to be responsible for the intramural hemorrhage in five patients (83%) and one patient, respectively." | 1.36 | Spontaneous intramural hematoma of the small intestine. ( Carkman, S; Ergüney, S; Korman, U; Ozben, V; Pekmezci, S; Saribeyoğlu, K; Somuncu, E, 2010) |
| "Indomethacin pretreatment (10 mg/kg p." | 1.27 | Protective action of SCH 12223 against experimentally induced gastric and intestinal lesions. ( Barnett, A; Brown, AD; Chiu, PJ; Gerhart, C; Siegel, M, 1988) |
| " These and control animals were sacrificed and, using inverted sacs, the rate of absorption of either dimethylnitrosamine and benzo(a)pyrene determined." | 1.26 | Use of inverted intestinal sacs to assess the effect of gastrointestinal insult on carcinogen absorption. ( Capel, ID; Cosier, RS; Pinnock, MH; Williams, DC, 1981) |
| " Dose-response curves in fasted and fed rats indicated that the fed rat was about eight times more susceptible to aspirin-induced intestinal damage than was the fasted rat, while the fasted rat was about 13 times more susceptible to aspirin-induced gastric damage than was the fed rat." | 1.25 | Aspirin: intestinal damage in rats. ( Brodie, DA; Hooke, KF; Tate, CL, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (30.91) | 18.7374 |
| 1990's | 6 (10.91) | 18.2507 |
| 2000's | 7 (12.73) | 29.6817 |
| 2010's | 22 (40.00) | 24.3611 |
| 2020's | 3 (5.45) | 2.80 |
| Authors | Studies |
|---|---|
| Handa, Y | 2 |
| Fukushima, S | 2 |
| Osawa, M | 2 |
| Murao, T | 3 |
| Handa, O | 3 |
| Matsumoto, H | 3 |
| Umegaki, E | 2 |
| Shiotani, A | 3 |
| Watanabe, T | 3 |
| Fujiwara, Y | 2 |
| Chan, FKL | 1 |
| Yo, S | 1 |
| Sakakibara, T | 1 |
| Beales, ILP | 1 |
| Kurokawa, S | 1 |
| Katsuki, S | 1 |
| Fujita, T | 1 |
| Saitoh, Y | 1 |
| Ohta, H | 1 |
| Nishikawa, K | 1 |
| Sato, Y | 2 |
| Ohira, K | 1 |
| Yamada, M | 1 |
| Kato, M | 1 |
| Ehrhard, F | 1 |
| Nazeyrollas, P | 1 |
| Brixi, H | 1 |
| Heurgue-Berlot, A | 1 |
| Thiéfin, G | 3 |
| Ishihara, M | 1 |
| Ohmiya, N | 1 |
| Nakamura, M | 1 |
| Funasaka, K | 1 |
| Miyahara, R | 1 |
| Ohno, E | 1 |
| Kawashima, H | 1 |
| Itoh, A | 1 |
| Hirooka, Y | 1 |
| Watanabe, O | 1 |
| Ando, T | 1 |
| Goto, H | 1 |
| Shim, KN | 1 |
| Song, EM | 1 |
| Jeen, YT | 1 |
| Kim, JO | 1 |
| Jeon, SR | 1 |
| Chang, DK | 1 |
| Song, HJ | 1 |
| Lim, YJ | 1 |
| Kim, JS | 1 |
| Ye, BD | 1 |
| Park, CH | 1 |
| Jeon, SW | 1 |
| Cheon, JH | 1 |
| Lee, KJ | 1 |
| Kim, JH | 1 |
| Jang, BI | 1 |
| Moon, JS | 1 |
| Chun, HJ | 1 |
| Choi, MG | 1 |
| Endo, H | 3 |
| Sakai, E | 2 |
| Kato, T | 1 |
| Umezawa, S | 1 |
| Higurashi, T | 2 |
| Ohkubo, H | 1 |
| Nakajima, A | 3 |
| Takeuchi, T | 1 |
| Sakata, Y | 1 |
| Tanigawa, T | 2 |
| Shiba, M | 1 |
| Naito, Y | 1 |
| Higuchi, K | 1 |
| Fujimoto, K | 1 |
| Yoshikawa, T | 1 |
| Arakawa, T | 3 |
| Pavlidis, P | 1 |
| Bjarnason, I | 3 |
| Pérez-Cuadrado-Robles, E | 1 |
| Quesada-Vázquez, N | 1 |
| Martínez-Andrés, B | 1 |
| Sánchez-Melgarejo, JF | 1 |
| Rubio-Mateos, JM | 1 |
| López-Higueras, A | 1 |
| Pérez-Cuadrado-Martínez, E | 1 |
| Suzuki, T | 1 |
| Masui, A | 1 |
| Nakamura, J | 1 |
| Shiozawa, H | 1 |
| Aoki, J | 1 |
| Nakae, H | 1 |
| Tsuda, S | 1 |
| Imai, J | 1 |
| Hideki, O | 1 |
| Matsushima, M | 1 |
| Mine, T | 1 |
| Tamura, A | 1 |
| Ohtsu, T | 1 |
| Asami, Y | 1 |
| Takagi, A | 1 |
| Benamouzig, R | 1 |
| Rácz, I | 1 |
| Hosono, K | 2 |
| Inamori, M | 2 |
| Kato, S | 2 |
| Nozaki, Y | 1 |
| Yoneda, K | 1 |
| Akiyama, T | 1 |
| Fujita, K | 1 |
| Takahashi, H | 2 |
| Yoneda, M | 2 |
| Abe, Y | 2 |
| Kirikoshi, H | 1 |
| Kobayashi, N | 1 |
| Kubota, K | 1 |
| Saito, S | 1 |
| Matsuhashi, N | 1 |
| Pilgrim, S | 1 |
| Velchuru, V | 1 |
| Waters, G | 1 |
| Tsiamis, A | 1 |
| Lal, R | 1 |
| Carkman, S | 1 |
| Ozben, V | 1 |
| Saribeyoğlu, K | 1 |
| Somuncu, E | 1 |
| Ergüney, S | 1 |
| Korman, U | 1 |
| Pekmezci, S | 1 |
| Tachecí, I | 1 |
| Kopácová, M | 1 |
| Rejchrt, S | 1 |
| Bures, J | 1 |
| Honda, K | 1 |
| Kawakami, M | 1 |
| Tarumi, K | 1 |
| Kusunoki, H | 1 |
| Hata, J | 1 |
| Haruma, K | 1 |
| Osada, T | 1 |
| Shibuya, T | 1 |
| Watanabe, S | 1 |
| Sekino, Y | 1 |
| Iida, H | 1 |
| Sakamoto, Y | 1 |
| Koide, T | 1 |
| Tokoro, C | 1 |
| Fujimori, S | 1 |
| Sakamoto, C | 1 |
| Mizukami, K | 1 |
| Murakami, K | 1 |
| Abe, T | 1 |
| Inoue, K | 1 |
| Uchida, M | 1 |
| Okimoto, T | 1 |
| Kodama, M | 1 |
| Fujioka, T | 1 |
| Tominaga, K | 1 |
| Otani, K | 1 |
| Nadatani, Y | 1 |
| Satoh, H | 1 |
| Takeuchi, K | 2 |
| Tanaka, A | 1 |
| Amagase, K | 1 |
| Lanas, A | 3 |
| Beaugerie, L | 1 |
| Qvigstad, G | 1 |
| Hatlen-Rebhan, P | 1 |
| Brenna, E | 1 |
| Waldum, HL | 1 |
| Leung, WK | 1 |
| Wong, VW | 1 |
| Sung, JJ | 1 |
| Chan, FK | 1 |
| Whittle, BJ | 1 |
| Chono, S | 1 |
| Yamada, H | 1 |
| Nakamura, H | 1 |
| Kobayashi, K | 1 |
| Capel, ID | 1 |
| Cosier, RS | 1 |
| Pinnock, MH | 1 |
| Williams, DC | 1 |
| Holsapple, MP | 1 |
| Yim, GK | 1 |
| Tsurumi, K | 1 |
| Kyuki, K | 1 |
| Fujimura, H | 1 |
| Cottafava, F | 1 |
| Brida Di Priò, S | 1 |
| Buono, S | 1 |
| Nardelli, E | 1 |
| Della Casa, C | 1 |
| Boeri, L | 1 |
| Dodero, P | 1 |
| Tabata, K | 1 |
| Okabe, S | 1 |
| Perkins, WE | 1 |
| Bianchi, RG | 1 |
| Tremont, SJ | 1 |
| Collins, PW | 1 |
| Casler, JJ | 1 |
| Fenton, RL | 1 |
| Wagner, GM | 1 |
| McGrath, MP | 1 |
| Stolzenbach, JC | 1 |
| Kowalski, DL | 1 |
| Cleophas, TJ | 1 |
| Tavenier, P | 1 |
| Niemeyer, MG | 1 |
| Somasundaram, S | 1 |
| Rafi, S | 1 |
| Hayllar, J | 1 |
| Sigthorsson, G | 1 |
| Jacob, M | 1 |
| Price, AB | 1 |
| Macpherson, A | 1 |
| Mahmod, T | 1 |
| Scott, D | 1 |
| Wrigglesworth, JM | 1 |
| Hirschowitz, BI | 2 |
| García-Sancho Martín, L | 1 |
| Sicot, C | 1 |
| Ivey, KJ | 1 |
| Baskin, WN | 1 |
| Krause, WJ | 1 |
| Terry, B | 1 |
| Sekar, MC | 1 |
| Chiu, PJ | 1 |
| Barnett, A | 1 |
| Siegel, M | 1 |
| Brown, AD | 1 |
| Gerhart, C | 1 |
| Ezer, E | 1 |
| Kaito, I | 1 |
| Sato, S | 1 |
| Reynolds, KW | 1 |
| Welch, CE | 1 |
| Hedberg, S | 1 |
| Goulston, S | 1 |
| Breen, K | 1 |
| Brodie, DA | 2 |
| Tate, CL | 1 |
| Hooke, KF | 1 |
| Cook, PG | 1 |
| Bauer, BJ | 1 |
| Dagle, GE | 1 |
14 reviews available for aspirin and Intestinal Diseases
| Article | Year |
|---|---|
Current knowledge on non-steroidal anti-inflammatory drug-induced small-bowel damage: a comprehensive review.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Gas | 2020 |
Small bowel injury in low-dose aspirin users.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capsule Endoscopy; Drug Administration Schedule; G | 2015 |
Aspirin Induced Adverse Effects on the Small and Large Intestine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Humans; | 2015 |
Non-steroidal anti-inflammatory drug induced injury to the small intestine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diagnosis, Differential; Humans; Intestinal Diseas | 2010 |
[Diagnosis and therapy of intestinal mucosal injury due to low-dose aspirin].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Intestinal Diseases; Intestinal Mu | 2010 |
[Actual status and vision of NSAIDs-induced intestinal injuries].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Ulcer; Humans; Intestinal Diseases; Intes | 2011 |
Small intestinal injury caused by NSAIDs/aspirin: finding new from old.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Intestinal Diseases; Intestine, S | 2012 |
Management of NSAID/aspirin-induced small intestinal damage by GI-sparing NSAIDs, anti-ulcer drugs and food constituents.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; | 2012 |
[Development of NSAID-induced small intestinal lesions - pathogenic role of COX inhibition].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclo | 2012 |
[Gastrointestinal complications related to NSAIDs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Diseases; Cyclooxygenase Inhibitors; Human | 2004 |
[Digestive complications of corticoid treatment].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aspirin; Colonic Diseases; Duodenal Ulcer; Eso | 1975 |
[The digestive system].
Topics: Anemia, Pernicious; Antibodies; Aspirin; Feces; Galactosidases; gamma-Globulins; Gastric Juice; Gast | 1969 |
Gastrointestinal hemorrhage. I. General considerations of diagnosis and the rapy.
Topics: Anus Diseases; Aspirin; Biliary Tract Diseases; Blood Coagulation Disorders; Burns; Child; Child, Pr | 1973 |
Gastroenterology in Australia, 1949-69.
Topics: Animals; Aspirin; Australia; Colitis, Ulcerative; Copper; Gastric Juice; Gastroenterology; Gastroint | 1970 |
6 trials available for aspirin and Intestinal Diseases
| Article | Year |
|---|---|
A randomized, double-blinded, placebo-controlled, multicenter trial, healing effect of rebamipide in patients with low-dose aspirin and/or non-steroidal anti-inflammatory drug induced small bowel injury.
Topics: Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscop | 2014 |
A multicenter, randomized, double-blind, placebo-controlled trial of high-dose rebamipide treatment for low-dose aspirin-induced moderate-to-severe small intestinal damage.
Topics: Aged; Alanine; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Dose-Response Relationship, Drug; Doub | 2015 |
Yogurt Containing Lactobacillus gasseri Mitigates Aspirin-Induced Small Bowel Injuries: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capsule Endoscopy; Double-Blind Method; Fema | 2017 |
Incidence of small bowel injury induced by low-dose aspirin: a crossover study using capsule endoscopy in healthy volunteers.
Topics: Adult; Aspirin; Capsule Endoscopy; Chi-Square Distribution; Cross-Over Studies; Dose-Response Relati | 2009 |
Efficacy of Lactobacillus casei treatment on small bowel injury in chronic low-dose aspirin users: a pilot randomized controlled study.
Topics: Aged; Aged, 80 and over; Anemia, Iron-Deficiency; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Dru | 2011 |
Aspirin-induced small bowel injuries and the preventive effect of rebamipide.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule E | 2011 |
35 other studies available for aspirin and Intestinal Diseases
| Article | Year |
|---|---|
P2Y12 Inhibitors Exacerbate Low-dose Aspirin-induced Small Bowel Injury in Dual Antiplatelet Therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Capsule Endoscopy; Female; Humans; Intestinal Diseases; Intestine, | 2021 |
A novel gene associated with small bowel bleeding in patients taking low-dose aspirin.
Topics: Aged; Aspirin; Capsule Endoscopy; Cytochrome P450 Family 4; Female; Gastrointestinal Hemorrhage; Gen | 2021 |
Misoprostol for Aspirin-Induced Small Bowel Enteropathy: A Small Step in the Right Direction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Humans; Intestinal Diseases; In | 2018 |
Proximal predominance of small bowel injury associated with uncoated low-dose aspirin therapy: a video capsule study in chronic users.
Topics: Aged; Aged, 80 and over; Anemia, Iron-Deficiency; Anti-Inflammatory Agents, Non-Steroidal; Anticoagu | 2013 |
Risk factors of symptomatic NSAID-induced small intestinal injury and diaphragm disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Capsul | 2014 |
Long-Term Outcomes of NSAID-Induced Small Intestinal Injury Assessed by Capsule Endoscopy in Korea: A Nationwide Multicenter Retrospective Study.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capsule Endoscopy; Female; Huma | 2015 |
Nonsteroidal anti-inflammatory drugs-induced small bowel enteropathy and obscure gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Capsule Endoscopy; Case-Control Studies | 2018 |
Low-dose aspirin and small bowel enteropathy: mountain or molehill?
Topics: Aspirin; Capsule Endoscopy; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small | 2009 |
Is low-dose aspirin really harmful to the small bowel?
Topics: Aspirin; Capsule Endoscopy; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small | 2009 |
Diaphragm disease and small bowel enteropathy due to nonsteroidal anti-inflammatory drugs: a surgical perspective.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Constriction, Pathologic; Diaphragm; Diclofe | 2011 |
Spontaneous intramural hematoma of the small intestine.
Topics: Adult; Aged; Anticoagulants; Aspirin; Hematoma; Hemophilia A; Humans; Intestinal Diseases; Intestine | 2010 |
Evaluation of RAPID(®) 5 Access software for examination of capsule endoscopies and reading of the capsule by an endoscopy nurse.
Topics: Aspirin; Capsule Endoscopy; Clinical Competence; Humans; Image Processing, Computer-Assisted; Intest | 2011 |
[Gastrointestinal bleeding associated with NSAIDs, antiplatelet therapy and anticoagulant agent].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Gastrointestinal Hemorrhage; Helic | 2012 |
Capsule endoscopy in clinical routine in patients with suspected disease of the small intestine: a 2-year prospective study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cycloo | 2006 |
Small bowel enteropathy associated with chronic low-dose aspirin therapy.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Intestinal Diseases; Male | 2007 |
Low-dose aspirin and small bowel enteropathy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Ileum; Intestinal Absorption; Intestinal D | 2007 |
Temporal relationship between cyclooxygenase inhibition, as measured by prostacyclin biosynthesis, and the gastrointestinal damage induced by indomethacin in the rat.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Indomethacin; Intestinal Diseases; Male; | 1981 |
[The role of endogenous prostaglandin in drug-induced gastrointestinal lesions--comparison of aspirin and indomethacin (author's transl)].
Topics: Animals; Aspirin; Dinoprostone; Gastric Mucosa; Indomethacin; Intestinal Diseases; Intestinal Mucosa | 1981 |
Use of inverted intestinal sacs to assess the effect of gastrointestinal insult on carcinogen absorption.
Topics: Animals; Aspirin; Benzopyrenes; Carcinogens; Cold Temperature; Dimethylnitrosamine; Dose-Response Re | 1981 |
Decreased gastrointestinal ulcerogenicity of chlordimeform, a basic anti-inflammatory agent.
Topics: Amidines; Animals; Anti-Inflammatory Agents; Aspirin; Chlorphenamidine; Intestinal Diseases; Male; R | 1981 |
Interaction of indomethacin and aspirin or mepirizole in rats as shown by gastrointestinal ulcerogenic and anti-inflammatory activities.
Topics: Animals; Aspirin; Biological Transport; Charcoal; Drug Interactions; Edema; Epirizole; Indomethacin; | 1980 |
[Thrombocytosis. Considerations on a case with intestinal thrombosis diagnosed at the age of 4 months and treated with platelet anti-aggregants].
Topics: Aspirin; Dipyridamole; Female; Humans; Infant; Intestinal Diseases; Thrombocytosis; Thrombosis | 1981 |
Effects of 16, 16-dimethyl prostaglandin E2 methyl ester on aspirin-and indomethacin-induced gastrointestinal lesions in dogs.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Aspirin; Dogs; Gastric Mucosa; Indomethacin; Intestinal Dis | 1980 |
Polymer delivery of the active isomer of misoprostol: a solution to the intestinal side effect problem.
Topics: Animals; Antacids; Aspirin; Biological Availability; Butadienes; Depression, Chemical; Diarrhea; Dog | 1994 |
The risk of emergency intestinal bleeding among users of acenocoumarin: a population-based cohort study.
Topics: Acenocoumarol; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cas | 1993 |
Mitochondrial damage: a possible mechanism of the "topical" phase of NSAID induced injury to the rat intestine.
Topics: Acetaminophen; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile | 1997 |
Intractable upper gastrointestinal ulceration due to aspirin in patients who have undergone surgery for peptic ulcer.
Topics: Aspirin; Female; Humans; Intestinal Diseases; Male; Middle Aged; Peptic Ulcer; Postoperative Complic | 1998 |
[Aspirin and surgery].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Diseases; Endoscopy; Gastroi | 1997 |
Effect of aspirin and acid on human jejunal mucosa. An ultrastructural study.
Topics: Administration, Oral; Aspirin; Humans; Hydrochloric Acid; Intestinal Diseases; Intestinal Mucosa; In | 1979 |
Objective evidence of aspirin use in both ulcer and nonulcer upper and lower gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Gastro | 1992 |
Protective action of SCH 12223 against experimentally induced gastric and intestinal lesions.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Aspirin; Ethanol; Gastric Mucosa; Indomethacin; In | 1988 |
Sodium-salicylate in contrast with acetylsalicylic acid prevents gastric antral and intestinal ulcers produced by indomethacin in the refed rat.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Eating; Female; Indomethacin; Intestinal Disease | 1985 |
Erosive gastritis with special reference to the role of aspirin and bile.
Topics: Acute Disease; Age Factors; Aged; Animals; Aspirin; Bile; Chronic Disease; Drainage; Female; Gastrec | 1974 |
Aspirin: intestinal damage in rats.
Topics: Animals; Aspirin; Azo Compounds; Food Deprivation; Ileum; Intestinal Diseases; Intestinal Mucosa; In | 1970 |
Indomethacin-induced intestinal lesions in the rat.
Topics: Administration, Oral; Animals; Antacids; Aspirin; Atropine; Bile Ducts; Bretylium Compounds; Chlorpr | 1970 |