Page last updated: 2024-10-23

aspirin and Interstitial Nephritis

aspirin has been researched along with Interstitial Nephritis in 41 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Analgesic nephropathy is part of a wider clinical syndrome associated with the abuse of APC compounds, that is, a minimum total intake of 2 kg of aspirin or phenacetin."3.65Analgesic nephropathy. ( Nanra, RS, 1976)
" In contrast to acute renal insufficiency that may already occur after a single NSAID dose, analgesic nephropathy is a disease caused by long-term intake of NSAID compound analgesics and predominantly affects the middle and old age."1.33[Chronic interstitial nephritis in an 18-year-old due to intake of a compound analgesic]. ( Janssen, U; Jochum, E, 2006)
" This relationship may represent a dose-response curve relating amount of analgesic intake to prevalence of nephropathy."1.27Renal disease from habitual antipyretic analgesic consumption: an assessment of the epidemiologic evidence. ( Buckalew, VM; Schey, HM, 1986)
"A renal biopsy showed a severe tubulointerstitial nephritis."1.27Naproxen-associated renal failure in a child with arthritis and inflammatory bowel disease. ( Balfe, JW; Baumal, R; Laxer, RM; Poucell, S; Silverman, ED, 1987)
"Aspirin ingestion was documented by multiple, random, unannounced blood salicylate levels."1.26Aspirin and analgesic nephropathy. ( Emkey, RD; Mills, JA, 1982)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199033 (80.49)18.7374
1990's4 (9.76)18.2507
2000's2 (4.88)29.6817
2010's2 (4.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schaffer, AC1
Grad, Y1
Ross, JJ1
Grad, YH1
Seifter, JL1
Levy, BD1
Loscalzo, J1
STUDER, A1
ZBINDEN, G1
FUST, B1
ABRAHAMS, C1
RUBENSTEIN, AH1
LEVIN, NW1
WUNDERLICH, U1
Jochum, E1
Janssen, U1
Dixit, MP1
Nguyen, C1
Carson, T1
Guedes, B1
Dixit, NM1
Bell, JM1
Wang, Y1
Clive, DM1
Stoff, JS1
Mullick, FG1
Maher, JF1
Emkey, RD1
Mills, JA1
Rossi, E1
Silvestri, MG1
Manari, A1
Savazzi, G1
Migone, L1
Chatterjee, GP1
Kleinknecht, D1
Kantachuvesiri, S1
Kaojarern, S1
Kitayaporn, D1
Phanichphant, S1
Sumethkul, V1
Wananukul, W1
Pongskul, C1
Arkaravichien, W1
Jankriengkri, S1
Chanchairujira, T1
Thurlow, W1
McLeish, KR1
Senitzer, D1
Gohara, AF1
Burry, A1
Cross, R1
Axelsen, R1
Handa, SP1
Goldberg, M4
Murray, TG2
Nanra, RS2
Murray, T2
Arger, PH1
Bluth, EI1
Radig, H1
Bialasiewicz, AA1
Gerding, H1
Helmchen, U1
Carmichael, J1
Shankel, SW1
Ehrich, JH1
Wurster, U1
Lütge, M1
Doehring, E1
Oemar, B1
Baños Gallardo, M1
Claros González, I1
Forascepi Roza, R1
Argüelles Toraño, M1
Buckalew, VM1
Schey, HM1
Laxer, RM1
Silverman, ED1
Balfe, JW1
Poucell, S1
Baumal, R1
Segasothy, M1
Muhaya, HM1
Musa, A1
Rajagopalan, K1
Lim, KJ1
Fatimah, Y1
Kamal, A1
Ahmad, KS1
Reeves, WB1
Foley, RJ1
Weinman, EJ1
Raaflaub, J1
Dubach, UC1
Wilson, DR1
Wigley, RD1
Wenger, J1
Einstein, S1
Kincaid-Smith, P1
Heidland, A1
Klütsch, K1
Spall, M1
Frohwein, H1
Gault, MH1
Rudwal, TC1
Engles, WD1
Dossetor, JB1

Reviews

8 reviews available for aspirin and Interstitial Nephritis

ArticleYear
Renal syndromes associated with nonsteroidal antiinflammatory drugs.
    The New England journal of medicine, 1984, Mar-01, Volume: 310, Issue:9

    Topics: Acute Kidney Injury; Adult; Animals; Anti-Inflammatory Agents; Anuria; Aspirin; Body Water; Electrol

1984
Interstitial nephritis, the nephrotic syndrome, and chronic renal failure secondary to nonsteroidal anti-inflammatory drugs.
    Seminars in nephrology, 1995, Volume: 15, Issue:3

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Humans; Kidney Failure, C

1995
Analgesic nephropathy and the renal concentrating mechanism.
    Pathology annual, 1977, Volume: 12 Pt 2

    Topics: Aging; Amyloidosis; Analgesics; Anemia, Sickle Cell; Animals; Aspirin; Calcinosis; Dehydration; Diab

1977
Analgesic abuse and renal disease.
    Annual review of medicine, 1975, Volume: 26

    Topics: Acetaminophen; Adult; Aged; Animals; Aspirin; Creatinine; Drug Combinations; Humans; Inactivation, M

1975
Analgesic abuse nephropathy.
    Urology, 1976, Volume: 7, Issue:2

    Topics: Analgesics; Aspirin; Calcinosis; Female; Humans; Kidney Failure, Chronic; Kidney Papillary Necrosis;

1976
Effects of nonsteroidal anti-inflammatory drugs on prostaglandins and renal function.
    The American journal of medicine, 1985, Volume: 78, Issue:6 Pt 1

    Topics: Anti-Inflammatory Agents; Aspirin; Epoprostenol; Fenoprofen; Glafenine; Glomerular Filtration Rate;

1985
[Pathogenesis of chronic interstitial nephritis following prolonged analgesic abuse].
    Klinische Wochenschrift, 1972, May-15, Volume: 50, Issue:10

    Topics: Analgesics; Aniline Compounds; Animals; Aspirin; Chronic Disease; Dogs; Drug Hypersensitivity; Ethyl

1972
Aspirin and the kidney.
    The New Zealand medical journal, 1971, Volume: 74, Issue:474

    Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Humans; Kidney; Kidney Diseases; Kidney Papillary Nec

1971

Other Studies

33 other studies available for aspirin and Interstitial Nephritis

ArticleYear
Interactive medical case. Bitter pills.
    The New England journal of medicine, 2010, Oct-14, Volume: 363, Issue:16

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Biopsy; Creatini

2010
Clinical problem-solving. Bitter pills.
    The New England journal of medicine, 2010, Nov-04, Volume: 363, Issue:19

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Diagnosis, Di

2010
[Further experimental studies on the problem of musused analgesics & interstitial nephritis].
    Schweizerische medizinische Wochenschrift, 1958, May-10, Volume: 88, Issue:19

    Topics: Analgesics; Aspirin; Nephritis; Nephritis, Interstitial; Phenacetin

1958
EXPERIMENTALLY INDUCED ANALGESIC NEPHRITIS IN RATS.
    Archives of pathology, 1964, Volume: 78

    Topics: Analgesics; Aspirin; Caffeine; Hemorrhage; Kidney Papillary Necrosis; Leukocytes; Lymphocytes; Nephr

1964
[Chronic interstitial nephritis in an 18-year-old due to intake of a compound analgesic].
    Medizinische Klinik (Munich, Germany : 1983), 2006, Oct-15, Volume: 101, Issue:10

    Topics: Acetaminophen; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Caffeine; Creat

2006
Non-steroidal anti-inflammatory drugs-associated acute interstitial nephritis with granular tubular basement membrane deposits.
    Pediatric nephrology (Berlin, Germany), 2008, Volume: 23, Issue:1

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basement Membrane; Huma

2008
Papillary necrosis, marked, associated with aspirin abuse and interstitial nephritis, acute and chronic.
    Military medicine, 1984, Volume: 149, Issue:10

    Topics: Aspirin; Humans; Kidney Papillary Necrosis; Male; Middle Aged; Nephritis, Interstitial

1984
Analgesic nephropathy. Observations, interpretations, and perspective on the low incidence in America.
    The American journal of medicine, 1984, Volume: 76, Issue:3

    Topics: Analgesics; Aspirin; Australia; Belgium; Dose-Response Relationship, Drug; Humans; Kidney Papillary

1984
Analgesic abuse and the kidney.
    Kidney international, 1980, Volume: 17, Issue:2

    Topics: Aged; Analgesics; Aspirin; Caffeine; Codeine; Drug Combinations; Humans; Kidney; Kidney Diseases; Ki

1980
Aspirin and analgesic nephropathy.
    JAMA, 1982, Jan-01, Volume: 247, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Creatinine; Female; History, 17th Century; Humans; Kidn

1982
Acute renal failure and piromidic acid.
    Nephron, 1982, Volume: 32, Issue:1

    Topics: Acute Kidney Injury; Aspirin; Biopsy; Drug Therapy, Combination; Female; Humans; Kidney; Middle Aged

1982
Nephrotic syndrome induced by tolmetin.
    JAMA, 1981, Oct-02, Volume: 246, Issue:14

    Topics: Arthritis, Rheumatoid; Aspirin; Female; Humans; Middle Aged; Nephritis, Interstitial; Nephrotic Synd

1981
Risk factors between analgesic use and chronic nephropathy in Thailand.
    The Southeast Asian journal of tropical medicine and public health, 1996, Volume: 27, Issue:2

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ca

1996
Analgesic nephropathy.
    The New England journal of medicine, 1998, Jul-02, Volume: 339, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Kidney Papillary Necrosis; Nephritis, Inte

1998
Acute interstitial nephritis in a patient with aspirin hypersensitivity.
    Clinical immunology and immunopathology, 1979, Volume: 14, Issue:1

    Topics: Acute Disease; Antibodies; Aspirin; Basement Membrane; Drug Hypersensitivity; Fluorescent Antibody T

1979
Analgesic nephropathy and urothelial carcinoma.
    Canadian Medical Association journal, 1979, Oct-06, Volume: 121, Issue:7

    Topics: Analgesics; Aspirin; Caffeine; Carcinoma, Transitional Cell; Codeine; Female; Humans; Kidney Neoplas

1979
Analgesic-associated nephropathy. An important cause of renal disease in the United States?
    The New England journal of medicine, 1978, Sep-28, Volume: 299, Issue:13

    Topics: Adult; Analgesics; Aspirin; Female; Humans; Nephritis, Interstitial; Phenacetin; United States

1978
Analgesic-associated nephropathy in the U.S.A.: epidemiologic, clinical and pathogenetic features.
    Kidney international, 1978, Volume: 13, Issue:1

    Topics: Acetaminophen; Adult; Aged; Analgesics; Animals; Aspirin; Creatinine; Drug Combinations; Female; Fol

1978
Analgesic nephropathy.
    The Medical journal of Australia, 1976, May-15, Volume: 1, Issue:20

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Co

1976
Renal papillary necrosis in rheumatoid arthritis.
    The Medical journal of Australia, 1975, Feb-15, Volume: 1, Issue:7

    Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Autopsy; Calcinosis; Female; Humans; Kidney; Kidney Pap

1975
[Tubulointerstitial nephritis and uveitis (TINU syndrome)].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1992, Volume: 89, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Aspirin; Drug Therapy, Combination; Female; Humans; Iridocyclit

1992
[Enzymuria and kidney diseases in childhood].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:12

    Topics: Acetylglucosaminidase; Adolescent; Aminopeptidases; Anti-Bacterial Agents; Aspirin; CD13 Antigens; C

1986
[Acute interstitial nephritis with renal failure secondary to drugs].
    Revista clinica espanola, 1987, Volume: 181, Issue:7

    Topics: Acute Disease; Acute Kidney Injury; Adolescent; Adult; Aspirin; Dipyrone; Female; Humans; Male; Midd

1987
Renal disease from habitual antipyretic analgesic consumption: an assessment of the epidemiologic evidence.
    Medicine, 1986, Volume: 65, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Kidney; Kidney Diseases; Kidney Failure, C

1986
Naproxen-associated renal failure in a child with arthritis and inflammatory bowel disease.
    Pediatrics, 1987, Volume: 80, Issue:6

    Topics: Adolescent; Arthritis, Juvenile; Aspirin; Colitis; Drug Therapy, Combination; Female; Humans; Kidney

1987
Analgesic use by leprosy patients.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1986, Volume: 54, Issue:3

    Topics: Acetaminophen; Adult; Aged; Analgesics; Aspirin; Female; Humans; Kidney Papillary Necrosis; Leprosy;

1986
Nephrotoxicity from nonsteroidal anti-inflammatory drugs.
    Southern medical journal, 1985, Volume: 78, Issue:3

    Topics: Acute Disease; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Aspirin; Female; Humans; Hyperka

1985
Analgesic nephropathy.
    Canadian Medical Association journal, 1972, Oct-21, Volume: 107, Issue:8

    Topics: Analgesics; Aspirin; Humans; Kidney Failure, Chronic; Nephritis, Interstitial; Phenacetin

1972
Acetaminophen, valadol, and analgesic renal injury.
    The Medical letter on drugs and therapeutics, 1971, Volume: 13, Issue:18

    Topics: Acetaminophen; Analgesics; Aspirin; Humans; Kidney Diseases; Kidney Papillary Necrosis; Nephritis, I

1971
The use and misuse of aspirin: a contemporary problem.
    The International journal of the addictions, 1970, Volume: 5, Issue:4

    Topics: Adult; Aged; Analgesics; Anemia, Hypochromic; Aspirin; Blood Coagulation; Blood Platelet Disorders;

1970
Analgesic nephropathy. A common form of renal disease in Australia.
    The Medical journal of Australia, 1969, Dec-06, Volume: 2, Issue:23

    Topics: Acetaminophen; Analgesics; Anemia; Animals; Aspirin; Australia; Caffeine; Diagnosis, Differential; D

1969
[Clinical and experimental studies on the phenacetin kidney].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1967, Volume: 73

    Topics: Aminohippuric Acids; Animals; Aspirin; Diuresis; Dogs; Guinea Pigs; Humans; Inulin; Kidney Diseases;

1967
Syndrome associated with the abuse of analgesics.
    Annals of internal medicine, 1968, Volume: 68, Issue:4

    Topics: Adult; Age Factors; Analgesics; Anemia; Animals; Aspirin; Caffeine; Cats; Dogs; Female; Guinea Pigs;

1968