aspirin has been researched along with Injuries, Spinal Cord in 10 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aspirin has been shown to exert several pharmacological effects by inducing the expression of the heme oxygenase-1 (HO-1) protein." | 1.48 | Aspirin suppresses neuronal apoptosis, reduces tissue inflammation, and restrains astrocyte activation by activating the Nrf2/HO-1 signaling pathway. ( Chang, L; Hongliang, D; Hongyu, W; Kang, Z; Mei, X; Shurui, C; Wei, W; Yuanlong, L; Yue, G; Zhaoliang, S; Zipeng, Z, 2018) |
| "The purpose of the present work was to study whether spinal cord injury (SCI) alters salicylate bioavailability after oral aspirin administration." | 1.30 | Effect of experimental spinal cord injury on salicylate bioavailability after oral aspirin administration. ( Fuentes-Lara, G; García-López, P; Guízar-Sahagún, G, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guha, L | 1 |
| Kumar, H | 1 |
| Chang, R | 1 |
| Scerbo, MH | 1 |
| Schmitt, KM | 1 |
| Adams, SD | 1 |
| Choi, TJ | 1 |
| Wade, CE | 1 |
| Holcomb, JB | 1 |
| Wei, W | 1 |
| Shurui, C | 1 |
| Zipeng, Z | 1 |
| Hongliang, D | 1 |
| Hongyu, W | 1 |
| Yuanlong, L | 1 |
| Kang, Z | 1 |
| Zhaoliang, S | 1 |
| Yue, G | 1 |
| Chang, L | 1 |
| Mei, X | 1 |
| COMARR, AE | 1 |
| CARNE, HO | 1 |
| Green, D | 1 |
| Rossi, EC | 1 |
| Yao, JS | 1 |
| Flinn, WR | 1 |
| Spies, SM | 1 |
| Kiwerski, J | 1 |
| Stover, SL | 1 |
| Fleming, WC | 1 |
| Guth, L | 1 |
| Zhang, Z | 1 |
| Roberts, E | 1 |
| Fuentes-Lara, G | 1 |
| Guízar-Sahagún, G | 1 |
| García-López, P | 1 |
| Fujita, Y | 1 |
| Shingu, T | 1 |
| Kurihara, M | 1 |
| Miyake, H | 1 |
| Kono, T | 1 |
| Tsujimura, M | 1 |
| Mori, K | 1 |
1 review available for aspirin and Injuries, Spinal Cord
| Article | Year |
|---|---|
Drug Repurposing for Spinal Cord Injury: Progress Towards Therapeutic Intervention for Primary Factors and Secondary Complications.
Topics: Aspirin; Drug Repositioning; Humans; Ibuprofen; Inflammation; Spinal Cord Injuries | 2023 |
1 trial available for aspirin and Injuries, Spinal Cord
| Article | Year |
|---|---|
Deep vein thrombosis in spinal cord injury: effect of prophylaxis with calf compression, aspirin, and dipyridamole.
Topics: Aspirin; Dipyridamole; Factor VIII; Humans; Leg; Platelet Aggregation; Pressure; Prospective Studies | 1982 |
8 other studies available for aspirin and Injuries, Spinal Cord
| Article | Year |
|---|---|
Early chemoprophylaxis is associated with decreased venous thromboembolism risk without concomitant increase in intraspinal hematoma expansion after traumatic spinal cord injury.
Topics: Adult; Anticoagulants; Aspirin; Chemoprevention; Female; Follow-Up Studies; Hematoma, Epidural, Spin | 2017 |
Aspirin suppresses neuronal apoptosis, reduces tissue inflammation, and restrains astrocyte activation by activating the Nrf2/HO-1 signaling pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Astrocytes; Heme Oxygenase (De | 2018 |
Acetylsalicylic acid and salicylamide: effect on renal calculosis in patients with spinal cord injury.
Topics: Aspirin; Calculi; Humans; Kidney; Kidney Calculi; Lithiasis; Nephrolithiasis; Salicylamides; Spinal | 1958 |
[Gastrointestinal hemorrhage during treatment of spinal cord injuries].
Topics: Anticoagulants; Aspirin; Gastrointestinal Hemorrhage; Humans; Middle Aged; Postoperative Care; Posto | 1982 |
Recurrent bacteriuria in complete spinal cord injury patients on external condom drainage.
Topics: Anti-Infective Agents, Urinary; Aspirin; Bacteriuria; Evaluation Studies as Topic; Hippurates; Human | 1980 |
Key role for pregnenolone in combination therapy that promotes recovery after spinal cord injury.
Topics: Analysis of Variance; Animals; Aspirin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Doub | 1994 |
Effect of experimental spinal cord injury on salicylate bioavailability after oral aspirin administration.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Availabi | 1999 |
Evaluation of a low dose administration of aspirin, dipyridamol and steroid. Therapeutic effects on motor function and protective effects on Na+-K+-activated ATPase activity against lipid peroxidation in an experimental model of spinal cord injury.
Topics: Animals; Aspirin; Dipyridamole; Drug Therapy, Combination; Enzyme Activation; Lipid Peroxides; Methy | 1985 |