Page last updated: 2024-10-23

aspirin and Infections, Coronavirus

aspirin has been researched along with Infections, Coronavirus in 21 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Both hypoxemia and a prothrombotic diathesis have been associated with more severe disease and increased risk of death."2.94Enhanced platelet inhibition treatment improves hypoxemia in patients with severe Covid-19 and hypercoagulability. A case control, proof of concept study. ( Forleo, GB; Radovanovic, D; Santus, P; Viecca, M, 2020)
"Indeed, Kawasaki disease is induced by overreaction of innate cells following exposition to various viruses, including herpes viruses which trigger STING."2.66Kawasaki-like diseases and thrombotic coagulopathy in COVID-19: delayed over-activation of the STING pathway? ( Berthelot, JM; Drouet, L; Lioté, F, 2020)
" Hence, whether ASA might be a safe and reasonable therapeutic candidate to be tested in clinical trials involving adults with COVID-19 deserves further attention."2.66Is Acetylsalicylic Acid a Safe and Potentially Useful Choice for Adult Patients with COVID-19 ? ( Bianconi, V; Fallarino, F; Pignatelli, P; Pirro, M; Sahebkar, A; Violi, F, 2020)
"BACKGROUND Coronavirus disease 2019 (COVID-19) infection commonly presents as fever, cough, and shortness of breath in adults."1.56Three Cases of Pediatric Multisystem Inflammatory Syndrome Associated with COVID-19 Due to SARS-CoV-2. ( Bauerfeld, C; Garcia, RU; Heidemann, SM; Martin, A; Sarnaik, AP; Tilford, B; Yagiela, L, 2020)
"In patients with STEMI, fibrinolysis achieved a comparable in-hospital and 30-day primary composite end point, as compared with those who received PPCI during the COVID-19 pandemic."1.56Fibrinolysis is a reasonable alternative for STEMI care during the COVID-19 pandemic. ( Huang, Z; Lin, Y; Su, H; Wang, N; Zhang, M, 2020)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (4.76)29.6817
2010's0 (0.00)24.3611
2020's20 (95.24)2.80

Authors

AuthorsStudies
Kwiatkowski, S1
Borowski, D1
Kajdy, A1
Poon, LC1
Rokita, W1
Wielgos, M1
Gavillet, M1
Rolnik, DL1
Hoffman, MK1
Panchaud, A1
Baud, D1
Viecca, M1
Radovanovic, D1
Forleo, GB1
Santus, P1
Rauf, A1
Vijayan, A1
John, ST1
Krishnan, R1
Latheef, A1
Gurbel, PA1
Bliden, KP1
Schrör, K1
Alay, H1
Can, FK1
Gözgeç, E1
Berthelot, JM1
Drouet, L1
Lioté, F1
Bianconi, V1
Violi, F1
Fallarino, F1
Pignatelli, P1
Sahebkar, A1
Pirro, M1
Lal, S1
Hashmi, J1
Heidemann, SM1
Tilford, B1
Bauerfeld, C1
Martin, A1
Garcia, RU1
Yagiela, L1
Sarnaik, AP1
Lee, WS1
Margolskee, E1
Mattioli, M1
Benfaremo, D1
Fustini, E1
Gennarini, S1
Trifan, G1
Hillmann, M1
Testai, FD1
Florêncio, FKZ1
Tenório, MO1
Macedo Júnior, ARA1
Lima, SG1
Kofman, AD1
Sizemore, EK1
Detelich, JF1
Albrecht, B1
Piantadosi, AL1
Haque, S1
Jawed, A1
Akhter, N1
Dar, SA1
Khan, F1
Mandal, RK1
Areeshi, MY1
Lohani, M1
Wahid, M1
Wang, N1
Zhang, M2
Su, H1
Huang, Z1
Lin, Y1
Ghati, N1
Roy, A1
Bhatnagar, S1
Bhati, S1
Bhushan, S1
Mahendran, M1
Thakur, A1
Tiwari, P1
Dwivedi, T1
Mani, K1
Gupta, R1
Mohan, A1
Garg, R1
Saxena, A1
Guleria, R1
Deepti, S1
Yang, Y1
Qidwai, U1
Burton, BJL1
Canepa, C1
Itsekson Hayosh, Z1
Schwammenthal, Y1
Orion, D1
Amici, C1
Di Caro, A1
Ciucci, A1
Chiappa, L1
Castilletti, C1
Martella, V1
Decaro, N1
Buonavoglia, C1
Capobianchi, MR1
Santoro, MG1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Dynamics of Hemostatic Parameters in COVID-19 and Comparison of Intervention Strategies Through Adaptive Clinical Trial[NCT04466670]Phase 2379 participants (Anticipated)Interventional2020-07-11Recruiting
Multicenter Randomized, Double-blind, Placebo-controlled, Clinical Trial of Acetylsalicylic Acid in the Prevention of Severe SARS-CoV2 Pneumonia in Hospitalised Patients (Asperum)[NCT04808895]Phase 3204 participants (Anticipated)Interventional2021-04-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for aspirin and Infections, Coronavirus

ArticleYear
Can an Old Ally Defeat a New Enemy?
    Circulation, 2020, 07-28, Volume: 142, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Betacoronavirus; Coronavirus Infections;

2020
Kawasaki-like diseases and thrombotic coagulopathy in COVID-19: delayed over-activation of the STING pathway?
    Emerging microbes & infections, 2020, Volume: 9, Issue:1

    Topics: Angiotensin II; Animals; Aspirin; Blood Coagulation Disorders; Coronavirus Infections; COVID-19; Dip

2020
Is Acetylsalicylic Acid a Safe and Potentially Useful Choice for Adult Patients with COVID-19 ?
    Drugs, 2020, Volume: 80, Issue:14

    Topics: Anti-Inflammatory Agents; Aspirin; Betacoronavirus; Blood Coagulation; Coronavirus Infections; COVID

2020

Trials

3 trials available for aspirin and Infections, Coronavirus

ArticleYear
Enhanced platelet inhibition treatment improves hypoxemia in patients with severe Covid-19 and hypercoagulability. A case control, proof of concept study.
    Pharmacological research, 2020, Volume: 158

    Topics: Aged; Aspirin; Betacoronavirus; Clopidogrel; Compassionate Use Trials; Coronavirus Infections; COVID

2020
Atorvastatin and Aspirin as Adjuvant Therapy in Patients with SARS-CoV-2 Infection: A structured summary of a study protocol for a randomised controlled trial.
    Trials, 2020, Oct-30, Volume: 21, Issue:1

    Topics: Adult; Aged; Aspirin; Atorvastatin; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug

2020
Indomethacin has a potent antiviral activity against SARS coronavirus.
    Antiviral therapy, 2006, Volume: 11, Issue:8

    Topics: Animals; Antiviral Agents; Aspirin; Cell Line; Chlorocebus aethiops; Coronavirus Infections; Coronav

2006

Other Studies

15 other studies available for aspirin and Infections, Coronavirus

ArticleYear
Why we should not stop giving aspirin to pregnant women during the COVID-19 pandemic.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2020, Volume: 55, Issue:6

    Topics: Aspirin; Betacoronavirus; Coronavirus Infections; COVID-19; Female; Humans; Infant; Infant, Newborn;

2020
Should we stop aspirin prophylaxis in pregnant women diagnosed with COVID-19?
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2020, Volume: 55, Issue:6

    Topics: Aspirin; Betacoronavirus; Coronavirus Infections; COVID-19; Female; Humans; Pandemics; Pneumonia, Vi

2020
Multisystem Inflammatory Syndrome with Features of Atypical Kawasaki Disease during COVID-19 Pandemic.
    Indian journal of pediatrics, 2020, Volume: 87, Issue:9

    Topics: Aspirin; Child, Preschool; Coronavirus Infections; COVID-19; Diagnosis, Differential; Humans; Immuno

2020
Cerebral Infarction in an Elderly Patient with Coronavirus Disease.
    Revista da Sociedade Brasileira de Medicina Tropical, 2020, Volume: 53

    Topics: Aged, 80 and over; Anticoagulants; Aspirin; Betacoronavirus; Cerebral Infarction; Coronavirus; Coron

2020
A Rare Finding of Upper Limb Deep Venous Thrombosis in a Patient with COVID-19.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:6

    Topics: Anticoagulants; Arm; Aspirin; Betacoronavirus; Coronavirus Infections; COVID-19; Edema; Enoxaparin;

2020
Three Cases of Pediatric Multisystem Inflammatory Syndrome Associated with COVID-19 Due to SARS-CoV-2.
    The American journal of case reports, 2020, Aug-13, Volume: 21

    Topics: Antipyretics; Aspirin; Betacoronavirus; Child; Child, Preschool; Conjunctivitis; Coronavirus Infecti

2020
Leukoerythroblastosis and plasmacytoid lymphocytes in a child with SARS-CoV-2-associated multisystem inflammatory syndrome.
    Blood, 2020, 08-13, Volume: 136, Issue:7

    Topics: Anti-Inflammatory Agents; Aspirin; Betacoronavirus; Child; Clinical Laboratory Techniques; Coronavir

2020
Atypical Spontaneous Hematomas in a Patient with Severe Coronavirus Disease 2019 (COVID-19).
    Seminars in thrombosis and hemostasis, 2020, Volume: 46, Issue:7

    Topics: Aged, 80 and over; Aspirin; Betacoronavirus; Coronavirus Infections; COVID-19; Erythrocyte Transfusi

2020
Acute Stroke as the Presenting Symptom of SARS-CoV-2 Infection in a Young Patient with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:10

    Topics: Adult; Aspirin; Betacoronavirus; CADASIL; Coronavirus Infections; COVID-19; Female; Host-Pathogen In

2020
Aspirin with or without statin in the treatment of endotheliitis, thrombosis, and ischemia in coronavirus disease.
    Revista da Sociedade Brasileira de Medicina Tropical, 2020, Volume: 53

    Topics: Aspirin; Betacoronavirus; Comorbidity; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; En

2020
A young adult with COVID-19 and multisystem inflammatory syndrome in children (MIS-C)-like illness: a case report.
    BMC infectious diseases, 2020, Sep-29, Volume: 20, Issue:1

    Topics: Adult; Aspirin; Betacoronavirus; Coronavirus Infections; Cough; COVID-19; COVID-19 Drug Treatment; D

2020
Acetylsalicylic acid (Aspirin): a potent medicine for preventing COVID-19 deaths caused by thrombosis and pulmonary embolism.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:18

    Topics: Aspirin; Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Pandemics; Platelet Aggregation

2020
Fibrinolysis is a reasonable alternative for STEMI care during the COVID-19 pandemic.
    The Journal of international medical research, 2020, Volume: 48, Issue:10

    Topics: Aged; Aspirin; Clopidogrel; Coronavirus Infections; COVID-19; Female; Fibrinolysis; Fibrinolytic Age

2020
Bilateral, vertical supranuclear gaze palsy following unilateral midbrain infarct.
    BMJ case reports, 2020, Nov-04, Volume: 13, Issue:11

    Topics: Aspirin; Atrial Fibrillation; Betacoronavirus; Blindness; Brain Stem Infarctions; Coronavirus Infect

2020
Can other coronavirus infections cause a cryptogenic stroke in a young patient?
    BMJ case reports, 2021, Mar-03, Volume: 14, Issue:3

    Topics: Acyclovir; Antiviral Agents; Aspirin; Coronavirus Infections; Coronavirus OC43, Human; COVID-19; Hum

2021