Page last updated: 2024-10-23

aspirin and Infection, Postoperative Wound

aspirin has been researched along with Infection, Postoperative Wound in 22 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this meta-analysis is to compare the efficacy and safety of aspirin and rivaroxaban in the prevention of venous thromboembolism (VTE) following either total knee arthroplasty or total hip arthroplasty."7.96Efficacy and safety of aspirin and rivaroxaban for venous thromboembolism prophylaxis after total hip or knee arthroplasty: A protocol for meta-analysis. ( Le, G; Luo, H; Tang, J; Xi, L; Yang, C; Zhang, M; Zhao, J, 2020)
"The rate of surgical site infection was similar between the aspirin group and the warfarin group (1."5.43Aspirin Can Be Used as Prophylaxis for Prevention of Venous Thromboembolism After Revision Hip and Knee Arthroplasty. ( Chen, AF; Deirmengian, GK; Heller, S; Maltenfort, M; Parvizi, J; Smith, EB, 2016)
"The purpose of this meta-analysis is to compare the efficacy and safety of aspirin and rivaroxaban in the prevention of venous thromboembolism (VTE) following either total knee arthroplasty or total hip arthroplasty."3.96Efficacy and safety of aspirin and rivaroxaban for venous thromboembolism prophylaxis after total hip or knee arthroplasty: A protocol for meta-analysis. ( Le, G; Luo, H; Tang, J; Xi, L; Yang, C; Zhang, M; Zhao, J, 2020)
"We performed a retrospective cohort study of 1677 patients undergoing coronary artery bypass surgery to determine the relationship of the preoperative use of aspirin plus clopidogrel vs aspirin alone to the 30-day incidence of postoperative surgical site infection and bacteremia."3.75Aspirin plus clopidogrel and risk of infection after coronary artery bypass surgery. ( Alejo, D; Baumgartner, WA; Blasco-Colmenares, E; Conte, JV; Faraday, N; Guallar, E; Pastor-Barriuso, R; Perl, TM; Sharrett, AR, 2009)
" Patients who received low-molecular-weight heparin for prophylaxis against deep venous thrombosis had a longer time until the postoperative wound was dry than did those treated with aspirin and mechanical foot compression or those who received Coumadin (warfarin); this difference was significant on the fifth postoperative day (p = 0."3.74Factors associated with prolonged wound drainage after primary total hip and knee arthroplasty. ( DeWal, H; Di Cesare, PE; Patel, VP; Preston, C; Sehgal, B; Walsh, M, 2007)
"The rate of surgical site infection was similar between the aspirin group and the warfarin group (1."1.43Aspirin Can Be Used as Prophylaxis for Prevention of Venous Thromboembolism After Revision Hip and Knee Arthroplasty. ( Chen, AF; Deirmengian, GK; Heller, S; Maltenfort, M; Parvizi, J; Smith, EB, 2016)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19907 (31.82)18.7374
1990's3 (13.64)18.2507
2000's3 (13.64)29.6817
2010's7 (31.82)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Le, G1
Yang, C1
Zhang, M1
Xi, L1
Luo, H1
Tang, J1
Zhao, J1
Hughes, LD1
Lum, J1
Mahfoud, Z1
Malik, RA1
Anand, A1
Charalambous, CP1
Pearcy, C1
Almahmoud, K1
Jackson, T1
Hartline, C1
Cahill, A1
Spence, L1
Kim, D1
Olatubosun, O1
Todd, SR1
Campion, EM1
Burlew, CC1
Regner, J1
Frazee, R1
Michaels, D1
Dissanaike, S1
Stewart, C1
Foley, N1
Nelson, P1
Agrawal, V1
Truitt, MS1
Kulshrestha, V1
Kumar, S1
Deirmengian, GK1
Heller, S1
Smith, EB1
Maltenfort, M1
Chen, AF1
Parvizi, J1
Bartolomé, J1
Lozano, MA1
Lucena, R1
Candel, FJ1
Blasco-Colmenares, E1
Perl, TM1
Guallar, E1
Baumgartner, WA1
Conte, JV1
Alejo, D1
Pastor-Barriuso, R1
Sharrett, AR1
Faraday, N1
Ruthmann, O1
Seitz, A1
Richter, S1
Marjanovic, G1
Olschewski, M1
Hopt, UT1
Fischer, A1
Schrag, HJ1
Kramer, E1
Hadad, E1
Westreich, M1
Shalom, A1
Chechik, O1
Goldstein, Y1
Behrbalk, E1
Kaufman, E1
Rabinovich, Y1
Kinduris, S1
Vaisvila, T1
Petronyte, J1
Budrikis, A1
Patel, VP1
Walsh, M1
Sehgal, B1
Preston, C1
DeWal, H1
Di Cesare, PE1
Leffert, RL1
Hackett, RL1
Radzivil, GG1
Musarov, AL1
Pankhurst, CL1
Lewis, DA1
Clark, DT1
Burton, NA1
Lefrak, EA1
Macmanus, Q1
Hill, A1
Marino, JA1
Speir, AM1
Akl, BF1
Albus, RA1
Massimiano, PS1
Fröhlich, M1
Wichmann, G1
Pyshkin, SA1
Kravets, NS1
Mirovich, DIu1
Drupp, IuG1
Berko, AT1
Agadzhanian, VV1
Kozlov, VA1
Livshits, MV1
Poveshchenko, AF1
Gromykhina, NIu1
Ivannikova, IIu1
Banach, J1
Malinowski, J1
Spychalska, M1
Zielińska, B1
Elcock, HW1
Fredrickson, JM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Nonrandomized, Study Comparing the Use of Aspirin and Intraoperative Blood Loss and Postoperative Complications Following Open Inguinal Hernia Repair.[NCT02084615]300 participants (Anticipated)Interventional2014-08-31Enrolling by invitation
The Blood Saving Effect and Wound-related Complications of Tranexamic Acid in Mininally Invasive Total Knee Arthroplasty With Rivaroxaban as Thromboprophylaxis[NCT02458729]Phase 4294 participants (Actual)Interventional2012-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aspirin and Infection, Postoperative Wound

ArticleYear
Comparison of Surgical Site Infection Risk Between Warfarin, LMWH, and Aspirin for Venous Thromboprophylaxis in TKA or THA: A Systematic Review and Meta-Analysis.
    JBJS reviews, 2020, 12-18, Volume: 8, Issue:12

    Topics: Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Heparin, L

2020

Trials

2 trials available for aspirin and Infection, Postoperative Wound

ArticleYear
DVT prophylaxis after TKA: routine anticoagulation vs risk screening approach - a randomized study.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:10

    Topics: Aged; Anticoagulants; Arthritis; Arthroplasty, Replacement, Knee; Aspirin; Chemoprevention; Female;

2013
Prophylactic application of an intra-alveolar socket medicament to reduce postextraction complications in HIV-seropositive patients.
    Oral surgery, oral medicine, and oral pathology, 1994, Volume: 77, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anesthetics, Local; Aspirin; Chlortetracycline; Dental Ca

1994

Other Studies

19 other studies available for aspirin and Infection, Postoperative Wound

ArticleYear
Efficacy and safety of aspirin and rivaroxaban for venous thromboembolism prophylaxis after total hip or knee arthroplasty: A protocol for meta-analysis.
    Medicine, 2020, Dec-04, Volume: 99, Issue:49

    Topics: Anticoagulants; Arthroplasty, Replacement, Knee; Aspirin; Blood Transfusion; Hemorrhage; Humans; Met

2020
Risky business? Investigating outcomes of patients undergoing urgent laparoscopic appendectomy on antithrombotic therapy.
    American journal of surgery, 2017, Volume: 214, Issue:6

    Topics: Adult; Appendectomy; Appendicitis; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Fe

2017
Aspirin Can Be Used as Prophylaxis for Prevention of Venous Thromboembolism After Revision Hip and Knee Arthroplasty.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:10

    Topics: Aged; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Fema

2016
[Peristomal cellulitis due to Magnusiomyces capitatus in a woman carrying percutaneous gastrostomy tube].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2017, Volume: 30, Issue:1

    Topics: Aged, 80 and over; Amphotericin B; Antifungal Agents; Aspirin; Cellulitis; Dermatomycoses; Drug Comb

2017
Aspirin plus clopidogrel and risk of infection after coronary artery bypass surgery.
    Archives of internal medicine, 2009, Apr-27, Volume: 169, Issue:8

    Topics: Aged; Aspirin; Bacteremia; Blood Transfusion; Clopidogrel; Cohort Studies; Coronary Artery Bypass; D

2009
[Percutaneous endoscopic gastrostomy. Complications with and without anticoagulation].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2010, Volume: 81, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Child; Child, Preschool; Clopid

2010
Lack of complications in skin surgery of patients receiving clopidogrel as compared with patients taking aspirin, warfarin, and controls.
    The American surgeon, 2010, Volume: 76, Issue:1

    Topics: Aged; Anticoagulants; Aspirin; Case-Control Studies; Clopidogrel; Dermatologic Surgical Procedures;

2010
Blood loss and complications following carotid endarterectomy in patients treated with clopidogrel.
    Vascular, 2012, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carotid Artery Diseases; Clopidogrel; Drug T

2012
[Bleeding after cardiac surgery: risk factors, frequency, and outcomes].
    Medicina (Kaunas, Lithuania), 2006, Volume: 42, Issue:7

    Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Cardiac Surgical Procedures; Diabetes Mellitus,

2006
Factors associated with prolonged wound drainage after primary total hip and knee arthroplasty.
    The Journal of bone and joint surgery. American volume, 2007, Volume: 89, Issue:1

    Topics: Aged; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Body Mass Index; Dra

2007
Aspergillus aortitis following replacement of aortic valve.
    The Journal of thoracic and cardiovascular surgery, 1967, Volume: 53, Issue:6

    Topics: Adult; Aortic Diseases; Aspergillus; Aspirin; Cardiac Catheterization; Cephalothin; Extracorporeal C

1967
[Intra-aortic administration of drugs in the complex treatment of diffuse peritonitis].
    Vestnik khirurgii imeni I. I. Grekova, 1982, Volume: 128, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Aorta; Aspirin; Catheterization; Drug Combinations;

1982
A reliable bridge to cardiac transplantation: the TCI left ventricular assist device.
    The Annals of thoracic surgery, 1993, Volume: 55, Issue:6

    Topics: Adult; Aspirin; Cardiac Output; Equipment Design; Female; Heart Transplantation; Heart-Assist Device

1993
[Comparative studies on the bacteriostatic effect of "Grisaldon" and "Cholinesalicylate gel"].
    Stomatologie der DDR, 1977, Volume: 27, Issue:7

    Topics: Anti-Infective Agents, Local; Aspirin; Bacteria; Candida albicans; Choline; Drug Combinations; Dry S

1977
[Use of acelysin solution in the treatment of acute purulent inflammatory diseases of soft tissues].
    Klinicheskaia khirurgiia, 1992, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Anti-Infective Agents; Aspirin; Child; Drug Combinations; Female;

1992
[Treatment of the umbilical cord stump with acetylsalicylic acid as a measure to prevent suppurative septic diseases].
    Akusherstvo i ginekologiia, 1989, Issue:9

    Topics: Anti-Infective Agents, Local; Antisepsis; Aspirin; Bandages; Humans; Infant, Newborn; Postnatal Care

1989
[Inhibition of prostaglandins in the prevention of wound infection in open fractures of the crural bones].
    Ortopediia travmatologiia i protezirovanie, 1989, Issue:10

    Topics: Aspirin; Femoral Artery; Fibula; Fractures, Open; Humans; Infusions, Intra-Arterial; Preoperative Ca

1989
[Clinical evaluation of Appernyl preparation].
    Czasopismo stomatologiczne, 1973, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Aspirin; Child; Dry Socket; Evaluation Studies as Topic; Humans; Periodontitis; S

1973
The effect of acetylsalicylic acid on thrombosis at microvenous anastomotic sites.
    The Journal of laryngology and otology, 1972, Volume: 86, Issue:8

    Topics: Animals; Aspirin; Collagen; Platelet Adhesiveness; Postoperative Complications; Rabbits; Surgical Wo

1972