aspirin has been researched along with Hypothermia, Accidental in 7 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It was shown that aspirin could further potentiate the hypothermia-induced closure time prolongations." | 9.20 | The effectiveness of low-dose desmopressin in improving hypothermia-induced impairment of primary haemostasis under influence of aspirin - a randomized controlled trial. ( Cheung, CW; Lee, Y; Leung, SW; Ng, KF; Tsui, PY, 2015) |
| "It was shown that aspirin could further potentiate the hypothermia-induced closure time prolongations." | 5.20 | The effectiveness of low-dose desmopressin in improving hypothermia-induced impairment of primary haemostasis under influence of aspirin - a randomized controlled trial. ( Cheung, CW; Lee, Y; Leung, SW; Ng, KF; Tsui, PY, 2015) |
| " On the other hand, the non-selective NOS inhibitor L-NAME but not aminoguanidine (a relatively selective inhibitor of iNOS), significantly potentiated the acid secretory and mucosal ulcerogenic responses in the stomach but reduced the duodenal damage in response to hypothermia, the effects being antagonized by co-administration of L-arginine." | 3.70 | Roles of endogenous prostaglandins and nitric oxide in gastroduodenal ulcerogenic responses induced in rats by hypothermic stress. ( Araki, H; Mizoguchi, H; Sugamoto, S; Suzuki, K; Takeuchi, K; Umdeda, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsui, PY | 1 |
| Cheung, CW | 1 |
| Lee, Y | 1 |
| Leung, SW | 1 |
| Ng, KF | 1 |
| al-Harbi, MM | 1 |
| Islam, MW | 1 |
| al-Shabanah, OA | 1 |
| al-Gharably, NM | 1 |
| Takeuchi, K | 1 |
| Suzuki, K | 1 |
| Araki, H | 1 |
| Mizoguchi, H | 1 |
| Sugamoto, S | 1 |
| Umdeda, M | 1 |
| Hall, MW | 1 |
| Goodman, PD | 1 |
| Alston, SM | 1 |
| Solen, KA | 1 |
| Parmar, NS | 1 |
| Tariq, M | 1 |
| Ageel, AM | 1 |
| Coldwell, BB | 1 |
| Boyd, EM | 1 |
| Stanfield, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Aspirin, in Vitro Hemodilution and Desmopressin on Platelet Dysfunction Associated With Mild Hypothermia in Healthy Volunteers[NCT01382134] | 60 participants (Actual) | Interventional | 2011-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for aspirin and Hypothermia, Accidental
| Article | Year |
|---|---|
The effectiveness of low-dose desmopressin in improving hypothermia-induced impairment of primary haemostasis under influence of aspirin - a randomized controlled trial.
Topics: Adenosine Diphosphate; Aspirin; Collagen; Deamino Arginine Vasopressin; Double-Blind Method; Epineph | 2015 |
6 other studies available for aspirin and Hypothermia, Accidental
| Article | Year |
|---|---|
Effect of acute administration of fish oil (omega-3 marine triglyceride) on gastric ulceration and secretion induced by various ulcerogenic and necrotizing agents in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Ethanol; Female; Fish Oils; Gastric Aci | 1995 |
Roles of endogenous prostaglandins and nitric oxide in gastroduodenal ulcerogenic responses induced in rats by hypothermic stress.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Atropine; Cyclooxygenase Inhibi | 1999 |
Hypothermia-induced platelet aggregation in heparinized flowing human blood: identification of a high responder subpopulation.
Topics: Alprostadil; Anemia, Hemolytic, Autoimmune; Aspirin; Blood Cell Count; Citric Acid; Cold Temperature | 2002 |
Studies on the gastroulcerogenic effects of pylorus ligation, hypothermic restraint stress, aspirin, indomethacin and reserpine in morphine dependent rats.
Topics: Animals; Aspirin; Gastric Acid; Hypothermia; Indomethacin; Ligation; Male; Morphine Dependence; Pylo | 1987 |
The acute rectal toxicity of acetylsalicylic acid.
Topics: Adrenal Glands; Animals; Aspirin; Ataxia; Body Weight; Brain; Coma; Diarrhea; Diuresis; Dyspnea; Fee | 1966 |
Fever in children in the tropics.
Topics: Anti-Bacterial Agents; Aspirin; Child; Child, Preschool; Chloroquine; Fever; Humans; Hypothermia; Ph | 1969 |