Page last updated: 2024-10-23

aspirin and Hypoplastic Left Heart Syndrome

aspirin has been researched along with Hypoplastic Left Heart Syndrome in 5 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Hypoplastic Left Heart Syndrome: A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.

Research Excerpts

ExcerptRelevanceReference
"Purpose Patients with hypoplastic left heart syndrome and its variants following palliation surgery are at risk for thrombosis."1.46Variability of antithrombotics use in patients with hypoplastic left heart syndrome and its variants following first- and second-stage palliation surgery: a national report using the National Pediatric Cardiology Quality Improvement Collaborative registry ( Anderson, JB; Beekman, RH; King, E; Nebbia, A; Ramachandran, P, 2017)
"Aspirin resistance was determined using thromboelastography with platelet mapping (TEG) and urine thromboxane (UTX)."1.42Aspirin Resistance in Single-Ventricle Physiology: Aspirin Prophylaxis Is Not Adequate to Inhibit Platelets in the Immediate Postoperative Period. ( Frank, S; Guleserian, K; Heistein, L; Journeycake, J; Lemler, M; Mir, A; Wolovitis, J, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mir, A1
Frank, S1
Journeycake, J1
Wolovitis, J1
Guleserian, K1
Heistein, L1
Lemler, M1
Emani, SM1
Ramachandran, P1
King, E1
Nebbia, A1
Beekman, RH1
Anderson, JB1
Romlin, BS1
Wåhlander, H1
Strömvall-Larsson, E1
Synnergren, M1
Baghaei, F1
Jeppsson, A1
Karl, TR1

Other Studies

5 other studies available for aspirin and Hypoplastic Left Heart Syndrome

ArticleYear
Aspirin Resistance in Single-Ventricle Physiology: Aspirin Prophylaxis Is Not Adequate to Inhibit Platelets in the Immediate Postoperative Period.
    The Annals of thoracic surgery, 2015, Volume: 99, Issue:6

    Topics: Aspirin; Blalock-Taussig Procedure; Dose-Response Relationship, Drug; Drug Resistance; Female; Follo

2015
Invited Commentary.
    The Annals of thoracic surgery, 2015, Volume: 99, Issue:6

    Topics: Aspirin; Blalock-Taussig Procedure; Drug Resistance; Female; Humans; Hypoplastic Left Heart Syndrome

2015
Variability of antithrombotics use in patients with hypoplastic left heart syndrome and its variants following first- and second-stage palliation surgery: a national report using the National Pediatric Cardiology Quality Improvement Collaborative registry
    Cardiology in the young, 2017, Volume: 27, Issue:4

    Topics: Aspirin; Cardiac Catheterization; Female; Fibrinolytic Agents; Humans; Hypoplastic Left Heart Syndro

2017
Monitoring of acetyl salicylic acid-induced platelet inhibition with impedance aggregometry in children with systemic-to-pulmonary shunts.
    Cardiology in the young, 2013, Volume: 23, Issue:2

    Topics: Aspirin; Blalock-Taussig Procedure; Double Outlet Right Ventricle; Electric Impedance; Female; Heart

2013
Spontaneous occlusion of systemic-to-pulmonary arterial shunts.
    Cardiology in the young, 1999, Volume: 9, Issue:5

    Topics: Anticoagulants; Aspirin; Child; Fibrinolytic Agents; Graft Occlusion, Vascular; Heparin; Humans; Hyp

1999