Page last updated: 2024-10-23

aspirin and Hypertrophy

aspirin has been researched along with Hypertrophy in 7 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Research Excerpts

ExcerptRelevanceReference
"We have previously shown that maximal over-the-counter doses of ibuprofen, compared with low doses of acetylsalicylic acid, reduce muscle hypertrophy in young individuals after 8 wk of resistance training."9.69Limited effect of over-the-counter doses of ibuprofen on mechanisms regulating muscle hypertrophy during resistance training in young adults. ( Apró, W; Gustafsson, T; Langlet, B; Lilja, M; Lundberg, TR; Martínez-Aranda, LM; Moberg, M; Rundqvist, H, 2023)
"The protective effect of aspirin against myocardial hypertrophy (MH) was studied."8.02The Protective Effect of Aspirin against Myocardial Hypertrophy in Rats. ( Fan, X; Liu, J; Ma, X; Wei, M; Wu, X; Xue, M; Zhang, H, 2021)
" The dosage of aspirin was 30 mg/kg orally during the acute febrile stage and 5-10 mg/kg orally after lysis of fever."6.67Histopathologic and coronary angiographic assessment of effectiveness of aspirin or aspirin-and-gammaglobulin in Kawasaki disease. ( Haneda, N; Mori, C, 1993)
"We have previously shown that maximal over-the-counter doses of ibuprofen, compared with low doses of acetylsalicylic acid, reduce muscle hypertrophy in young individuals after 8 wk of resistance training."5.69Limited effect of over-the-counter doses of ibuprofen on mechanisms regulating muscle hypertrophy during resistance training in young adults. ( Apró, W; Gustafsson, T; Langlet, B; Lilja, M; Lundberg, TR; Martínez-Aranda, LM; Moberg, M; Rundqvist, H, 2023)
"The protective effect of aspirin against myocardial hypertrophy (MH) was studied."4.02The Protective Effect of Aspirin against Myocardial Hypertrophy in Rats. ( Fan, X; Liu, J; Ma, X; Wei, M; Wu, X; Xue, M; Zhang, H, 2021)
" The dosage of aspirin was 30 mg/kg orally during the acute febrile stage and 5-10 mg/kg orally after lysis of fever."2.67Histopathologic and coronary angiographic assessment of effectiveness of aspirin or aspirin-and-gammaglobulin in Kawasaki disease. ( Haneda, N; Mori, C, 1993)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Lilja, M1
Moberg, M1
Apró, W1
Martínez-Aranda, LM1
Rundqvist, H1
Langlet, B1
Gustafsson, T1
Lundberg, TR1
Wu, X1
Wei, M1
Zhang, H1
Fan, X1
Ma, X1
Liu, J1
Xue, M1
Ma, KL1
Liu, L1
Zhang, Y1
Wang, GH1
Hu, ZB1
Chen, PP1
Lu, J1
Lu, CC1
Gong, TK1
Gong, YX1
Liu, BC1
Haneda, N1
Mori, C1
Makino, H1
Tanaka, I1
Mukoyama, M1
Sugawara, A1
Mori, K1
Muro, S1
Suganami, T1
Yahata, K1
Ishibashi, R1
Ohuchida, S1
Maruyama, T1
Narumiya, S1
Nakao, K1
Chaudhuri, G1
Goldman, M1
Poppens, CA1

Trials

2 trials available for aspirin and Hypertrophy

ArticleYear
Limited effect of over-the-counter doses of ibuprofen on mechanisms regulating muscle hypertrophy during resistance training in young adults.
    Journal of applied physiology (Bethesda, Md. : 1985), 2023, 03-01, Volume: 134, Issue:3

    Topics: Aspirin; Female; Humans; Hypertrophy; Ibuprofen; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Re

2023
Histopathologic and coronary angiographic assessment of effectiveness of aspirin or aspirin-and-gammaglobulin in Kawasaki disease.
    Acta paediatrica Japonica : Overseas edition, 1993, Volume: 35, Issue:4

    Topics: Acute Disease; Aspirin; Biopsy; Cardiomyopathies; Child; Child, Preschool; Coronary Aneurysm; Corona

1993

Other Studies

5 other studies available for aspirin and Hypertrophy

ArticleYear
The Protective Effect of Aspirin against Myocardial Hypertrophy in Rats.
    BioMed research international, 2021, Volume: 2021

    Topics: Animals; Apoptosis; Aspirin; Blood Pressure; Body Weight; Cardiotonic Agents; Disease Models, Animal

2021
Aspirin attenuates podocyte injury in diabetic rats through overriding cyclooxygenase-2-mediated dysregulation of LDL receptor pathway.
    International urology and nephrology, 2019, Volume: 51, Issue:3

    Topics: Albuminuria; Animals; Aspirin; Creatinine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines;

2019
Prevention of diabetic nephropathy in rats by prostaglandin E receptor EP1-selective antagonist.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:7

    Topics: Animals; Aspirin; Autocrine Communication; Cells, Cultured; Cinnamates; Cyclooxygenase Inhibitors; D

2002
Inhibition by aspirin and indomethacin of uterine hypertrophy induced by an IUD.
    Journal of reproduction and fertility, 1975, Volume: 43, Issue:1

    Topics: Animals; Aspirin; Castration; Fallopian Tubes; Female; Hydrocortisone; Hypertrophy; Indomethacin; In

1975
Inhibition of unilateral ovarian compensatory hypertrophy in the rat by ingestion of aspirin.
    Toxicology and applied pharmacology, 1973, Volume: 24, Issue:1

    Topics: Animals; Aspirin; Body Weight; Castration; Diet; Female; Gonadotropins, Pituitary; Hypertrophy; Orga

1973