Page last updated: 2024-10-23

aspirin and Hyperplasia

aspirin has been researched along with Hyperplasia in 58 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"compared with aspirin monotherapy, the combination of aspirin plus clopidogrel did not significantly reduce the process of SVG intimal hyperplasia 1 year after coronary artery bypass grafting."9.14Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) Trial. ( Delarochelliere, R; Kulik, A; Le May, MR; Mesana, TG; Naidoo, S; Ruel, M; Tardif, JC; Voisine, P; Wells, GA, 2010)
"We sought to evaluate the impact of cilostazol on neointimal hyperplasia after drug-eluting stent (DES) implantation in patients with diabetes mellitus (DM)."9.13Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im ( Cho, YH; Choi, SW; Chun, KJ; Hong, MK; Kim, HS; Kim, JH; Kim, YH; Ko, JK; Lee, CW; Lee, JH; Lee, NH; Lee, SW; Park, DW; Park, JH; Park, SJ; Park, SW; Seong, IW; Yun, SC, 2008)
"To assess the efficacy of fertility-sparing treatment using medroxyprogesterone acetate (MPA) for endometrial carcinoma (EC) and atypical endometrial hyperplasia (AH) in young women."9.12Multicenter phase II study of fertility-sparing treatment with medroxyprogesterone acetate for endometrial carcinoma and atypical hyperplasia in young women. ( Fukunaga, M; Hatae, M; Hiura, M; Iwasaka, T; Kamura, T; Kodama, S; Konishi, I; Nakanishi, T; Saito, T; Saji, F; Sakamoto, A; Sasaki, H; Terakawa, N; Tsuda, H; Ushijima, K; Yaegashi, N; Yahata, H; Yasugi, T; Yoshikawa, H, 2007)
"This study was designed to investigate the efficacy of cilostazol on the prevention of in-stent neointimal hyperplasia as measured by both quantitative coronary angiography (CAG) and volumetric intravascular ultrasound (IVUS)."9.12Effect of cilostazol on in-stent neointimal hyperplasia after coronary artery stenting: a quantative coronary angiography and volumetric intravascular ultrasound study. ( Choi, D; Jang, Y; Jung, JH; Ko, YG; Min, PK; Shim, WH, 2007)
"Paclitaxel-eluting stents used with conventional antiplatelet therapy effectively inhibit restenosis and neointimal hyperplasia, with a safety profile similar to that of standard stents."9.10A paclitaxel-eluting stent for the prevention of coronary restenosis. ( Choi, D; Ho, DS; Hong, MK; Jang, Y; Lam, R; Lee, CW; Mintz, GS; Park, SJ; Park, SW; Raizner, AE; Shim, WH; Weissman, NJ, 2003)
" This study aimed to investigate the effects of aspirin on non-specific inflammation developing into cancer."8.12Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation. ( Chen, Y; Diao, T; Li, D; Shang, G; Shi, L; Sun, L; Yin, X, 2022)
"Data were compared between asthmatic patients who reported exacerbations after aspirin ingestion and those who did not."7.73Chronic hyperplastic eosinophilic sinusitis as a predictor of aspirin-exacerbated respiratory disease. ( Borish, L; Hunt, J; Mascia, K; Patrie, J; Phillips, CD; Steinke, JW, 2005)
"Previous studies have shown that agents such as indomethacin and hydrocortisone act to reduce the level of epidermal hyperplasia produced by various chemical, but little information is available about the effects of such anti-inflammatory agents on the induction of hyperplasia in oral mucosa."7.67Effects of the anti-inflammatory agents indomethacin, metiamide and acetylsalicylic acid on the induction of hyperplasia in hamster cheek-pouch epithelium and ear epidermis. ( Harris, RR; Mackenzie, IC, 1984)
"This experiment evaluated the effect of aspirin (ASA) on the patency and development of intimal hyperplasia in autologous, small caliber, arterial end-to-side anastomosis."7.67Patency and intimal hyperplasia: the effect of aspirin on small arterial anastomosis. ( Henderson, T; Moore, WS; Quiñones-Baldrich, WJ; Ziomek, S, 1988)
"The combination of aspirin and dipyridamole is currently used to prevent intimal hyperplasia and to improve long-term vein graft patency following myocardial revascularization."7.67Comparison of cod-liver oil and aspirin-dipyridamole for the prevention of intimal hyperplasia in autologous vein grafts. ( Cameron, C; Landymore, RW; MacAulay, M; Sheridan, B, 1986)
"Aspirin has anti-inflammatory and antineoplastic activity."5.35Effects of aspirin on the development of Helicobacter pylori-induced gastric inflammation and heterotopic proliferative glands in Mongolian gerbils. ( Chan, AO; Chen, MH; Cho, CH; Gu, Q; Hu, PJ; Li, GQ; Liang, YJ; Lin, HL; Qiao, L; So, WH; Tatematsu, M; Tsukamoto, T; Wong, BC; Xia, HH; Yuen, MF, 2008)
"However, systemic study of thrombus formation in vein grafts is still lacking, and few effective techniques are available to prevent this event."5.32Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. ( Hu, Y; Mayr, U; Thompson, WD; Torsney, E; Xu, Q; Zou, Y, 2004)
"The aspirin was started before operation and continued for 6 weeks after operation, at which time the endarterectomized vessels were excised."5.27Early healing after carotid endarterectomy: effect of high- and low-dose aspirin on thrombosis and early neointimal hyperplasia in a nonhuman primate model. ( Bush, HL; Jakubowski, JA; Sentissi, JM, 1988)
"compared with aspirin monotherapy, the combination of aspirin plus clopidogrel did not significantly reduce the process of SVG intimal hyperplasia 1 year after coronary artery bypass grafting."5.14Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) Trial. ( Delarochelliere, R; Kulik, A; Le May, MR; Mesana, TG; Naidoo, S; Ruel, M; Tardif, JC; Voisine, P; Wells, GA, 2010)
"We sought to evaluate the impact of cilostazol on neointimal hyperplasia after drug-eluting stent (DES) implantation in patients with diabetes mellitus (DM)."5.13Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im ( Cho, YH; Choi, SW; Chun, KJ; Hong, MK; Kim, HS; Kim, JH; Kim, YH; Ko, JK; Lee, CW; Lee, JH; Lee, NH; Lee, SW; Park, DW; Park, JH; Park, SJ; Park, SW; Seong, IW; Yun, SC, 2008)
"To assess the efficacy of fertility-sparing treatment using medroxyprogesterone acetate (MPA) for endometrial carcinoma (EC) and atypical endometrial hyperplasia (AH) in young women."5.12Multicenter phase II study of fertility-sparing treatment with medroxyprogesterone acetate for endometrial carcinoma and atypical hyperplasia in young women. ( Fukunaga, M; Hatae, M; Hiura, M; Iwasaka, T; Kamura, T; Kodama, S; Konishi, I; Nakanishi, T; Saito, T; Saji, F; Sakamoto, A; Sasaki, H; Terakawa, N; Tsuda, H; Ushijima, K; Yaegashi, N; Yahata, H; Yasugi, T; Yoshikawa, H, 2007)
"This study was designed to investigate the efficacy of cilostazol on the prevention of in-stent neointimal hyperplasia as measured by both quantitative coronary angiography (CAG) and volumetric intravascular ultrasound (IVUS)."5.12Effect of cilostazol on in-stent neointimal hyperplasia after coronary artery stenting: a quantative coronary angiography and volumetric intravascular ultrasound study. ( Choi, D; Jang, Y; Jung, JH; Ko, YG; Min, PK; Shim, WH, 2007)
"Paclitaxel-eluting stents used with conventional antiplatelet therapy effectively inhibit restenosis and neointimal hyperplasia, with a safety profile similar to that of standard stents."5.10A paclitaxel-eluting stent for the prevention of coronary restenosis. ( Choi, D; Ho, DS; Hong, MK; Jang, Y; Lam, R; Lee, CW; Mintz, GS; Park, SJ; Park, SW; Raizner, AE; Shim, WH; Weissman, NJ, 2003)
" This study aimed to investigate the effects of aspirin on non-specific inflammation developing into cancer."4.12Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation. ( Chen, Y; Diao, T; Li, D; Shang, G; Shi, L; Sun, L; Yin, X, 2022)
"Reducing the dose of sirolimus eluting from a biocompatible HAp coated stent reduces signs of delayed vascular healing, without affecting neointimal hyperplasia."3.75Lowering the dose of sirolimus, released from a nonpolymeric hydroxyapatite coated coronary stent, reduces signs of delayed healing. ( Peters-Krabbendam, I; Serruys, PW; Sorop, O; van Beusekom, HM; van der Giessen, WJ, 2009)
"Data were compared between asthmatic patients who reported exacerbations after aspirin ingestion and those who did not."3.73Chronic hyperplastic eosinophilic sinusitis as a predictor of aspirin-exacerbated respiratory disease. ( Borish, L; Hunt, J; Mascia, K; Patrie, J; Phillips, CD; Steinke, JW, 2005)
"Aspirin is frequently used after vascular reconstruction to pharmacologically prevent graft occlusion and to suppress the development of myointimal hyperplasia in vascular surgery, but its efficacy is controversial."3.69Aspirin enhances platelet-derived growth factor-induced vascular smooth muscle cell proliferation. ( Bredenberg, CE; Couper, L; Harvey, R; Himmelfarb, J, 1997)
"At 4 weeks, the degree of intimal hyperplasia of the graft of E5510 group was significantly less than that of the Aspirin group and the Control group (p < 0."3.69The inhibition of canine vein graft intimal thickening using a newly developed antiplatelet agent. ( Eguchi, D; Itoh, H; Kawasaki, K; Komori, K; Kuma, S; Mawatari, K; Okazaki, J; Onohara, T; Sugimachi, K, 1997)
"The purpose of this study was to evaluate the efficacy of three drugs (cilazapril, cyclosporine, and aspirin) in modulating the progression of intimal hyperplasia during short postoperative times in short-segment, autogenous vein bypass grafts in a canine model."3.68Pharmacologic modulation of intimal hyperplasia in canine vein interposition grafts. ( Evancho, MM; Hirko, MK; McShannic, JR; Schmidt, SP; Sharp, WV; Siebert, JD; Sims, RL, 1993)
"Previous studies have shown that agents such as indomethacin and hydrocortisone act to reduce the level of epidermal hyperplasia produced by various chemical, but little information is available about the effects of such anti-inflammatory agents on the induction of hyperplasia in oral mucosa."3.67Effects of the anti-inflammatory agents indomethacin, metiamide and acetylsalicylic acid on the induction of hyperplasia in hamster cheek-pouch epithelium and ear epidermis. ( Harris, RR; Mackenzie, IC, 1984)
"The combination of aspirin and dipyridamole is currently used to prevent intimal hyperplasia and to improve long-term vein graft patency following myocardial revascularization."3.67Comparison of cod-liver oil and aspirin-dipyridamole for the prevention of intimal hyperplasia in autologous vein grafts. ( Cameron, C; Landymore, RW; MacAulay, M; Sheridan, B, 1986)
"The effect of aspirin, reserpine, and flurbiprofen on in vivo platelet function and intimal smooth muscle cell hyperplasia in rat carotid arteries subjected to endothelial injury was investigated and related to the effect of these drugs on in vitro platelet aggregation."3.65Failure of certain antiplatelet drugs to affect myointimal thickening following arterial endothelial injury in the rat. ( Clowes, AW; Karnovsky, MJ, 1977)
"Aspirin was administered daily for 1 month prior and 4 months following aortic injury."2.38The effect of prolonged aspirin therapy on experimental balloon-catheter arterial wall injury. ( Connell, RS; Galey, WT; Jacobson, S; Shoemake, RG; Trune, DR; Vetto, RM; Yeager, RA, 1990)
"Aspirin has anti-inflammatory and antineoplastic activity."1.35Effects of aspirin on the development of Helicobacter pylori-induced gastric inflammation and heterotopic proliferative glands in Mongolian gerbils. ( Chan, AO; Chen, MH; Cho, CH; Gu, Q; Hu, PJ; Li, GQ; Liang, YJ; Lin, HL; Qiao, L; So, WH; Tatematsu, M; Tsukamoto, T; Wong, BC; Xia, HH; Yuen, MF, 2008)
"However, systemic study of thrombus formation in vein grafts is still lacking, and few effective techniques are available to prevent this event."1.32Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. ( Hu, Y; Mayr, U; Thompson, WD; Torsney, E; Xu, Q; Zou, Y, 2004)
"The aspirin was started before operation and continued for 6 weeks after operation, at which time the endarterectomized vessels were excised."1.27Early healing after carotid endarterectomy: effect of high- and low-dose aspirin on thrombosis and early neointimal hyperplasia in a nonhuman primate model. ( Bush, HL; Jakubowski, JA; Sentissi, JM, 1988)
"Aspirin treatment (3, 20, or 40 min) resulted in alterations in tight junction complex morphology and permeability."1.27Effects of aspirin on tight junction structure of the canine gastric mucosa. ( McGinley, D; Meyer, RA; Posalaky, Z, 1986)

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199020 (34.48)18.7374
1990's11 (18.97)18.2507
2000's15 (25.86)29.6817
2010's9 (15.52)24.3611
2020's3 (5.17)2.80

Authors

AuthorsStudies
Koga, Y1
Kihara, Y1
Okada, M1
Inoue, Y1
Tochizawa, S1
Toga, K1
Tachibana, K1
Kimura, Y1
Nishi, T1
Hidaka, H1
Chen, Y1
Sun, L1
Li, D1
Yin, X1
Shang, G1
Diao, T1
Shi, L1
Guida, GA1
Angelini, GD1
Ho, JP1
Galex, IA1
Sadeghi, NB1
Weledji, N1
Cabello Bermudez, SI1
Mitchell, BA1
Bush, DM1
Yap, E1
Davis, NC1
Catalino, MP1
Godfrey, V1
Nielsen, JN1
Lee, YZ1
Sasaki-Adams, DM1
Antigüedad-Muñoz, J1
de la Riva, P1
Arenaza Choperena, G1
Muñoz Lopetegi, A1
Andrés Marín, N1
Fernández-Eulate, G1
Moreno Valladares, M1
Martínez Zabaleta, M1
Lee, CH1
Yu, CY1
Chang, SH1
Hung, KC1
Liu, SJ1
Wang, CJ1
Hsu, MY1
Hsieh, IC1
Chen, WJ1
Ko, YS1
Wen, MS1
Petri, MH1
Laguna-Fernandez, A1
Tseng, CN1
Hedin, U1
Perretti, M1
Bäck, M1
Costa, F2
Vranckx, P2
Leonardi, S2
Moscarella, E1
Ando, G1
Calabro, P1
Oreto, G1
Zijlstra, F1
Valgimigli, M3
Gargiulo, G2
Ariotti, S2
Biscaglia, S1
Campo, G1
Esposito, G1
Windecker, S2
Franzone, A1
Piccolo, R1
Marino, M1
Santucci, A1
Baldo, A1
Magnani, G1
Moschovitis, A1
Hemetsberger, R1
Farhan, S1
Strehblow, C1
Sperker, W1
Pavo, I1
Petrasi, Z1
Hemetsberger, H1
Posa, A1
Huber, K1
Glogar, D1
Gyöngyösi, M1
van der Giessen, WJ3
Sorop, O1
Serruys, PW3
Peters-Krabbendam, I1
van Beusekom, HM2
Weale, AR1
Cooper, DG1
Kulik, A1
Le May, MR1
Voisine, P1
Tardif, JC1
Delarochelliere, R1
Naidoo, S1
Wells, GA1
Mesana, TG1
Ruel, M1
Gasparovic, H1
Petricevic, M1
Biocina, B1
Bisdas, T1
Haverich, A1
Teebken, OE1
Park, SJ2
Shim, WH2
Ho, DS1
Raizner, AE1
Park, SW2
Hong, MK2
Lee, CW2
Choi, D2
Jang, Y2
Lam, R1
Weissman, NJ1
Mintz, GS1
Torsney, E1
Mayr, U1
Zou, Y1
Thompson, WD1
Hu, Y1
Xu, Q1
Wijns, W1
Sianos, G1
de Scheerder, I1
van den Heuvel, PA1
Rutsch, W1
Glogar, HD1
Macaya, C1
Materne, PH1
Veldhof, S1
Vonhausen, H1
Otto-Terlouw, PC1
Melero, JM1
Porras, C1
Such, M1
Olalla, E1
Alonso, J1
Mascia, K1
Borish, L1
Patrie, J1
Hunt, J1
Phillips, CD1
Steinke, JW1
Finn, AV1
Joner, M1
Nakazawa, G1
Kolodgie, F1
Newell, J1
John, MC1
Gold, HK1
Virmani, R1
Ushijima, K1
Yahata, H1
Yoshikawa, H1
Konishi, I1
Yasugi, T1
Saito, T2
Nakanishi, T1
Sasaki, H1
Saji, F1
Iwasaka, T1
Hatae, M1
Kodama, S1
Terakawa, N1
Yaegashi, N1
Hiura, M1
Sakamoto, A1
Tsuda, H1
Fukunaga, M1
Kamura, T1
Min, PK1
Jung, JH1
Ko, YG1
Zou, RJ1
Zou, LJ1
Huang, SD1
Wang, Y1
Han, L1
Ji, GY1
Xu, ZY1
Li, GQ1
Xia, HH1
Chen, MH1
Tsukamoto, T1
Tatematsu, M1
Gu, Q1
Qiao, L1
Cho, CH1
So, WH1
Yuen, MF1
Hu, PJ1
Liang, YJ1
Lin, HL1
Chan, AO1
Wong, BC1
Lee, SW1
Kim, YH1
Yun, SC1
Park, DW1
Kim, HS1
Ko, JK1
Park, JH1
Lee, JH1
Choi, SW1
Seong, IW1
Cho, YH1
Lee, NH1
Kim, JH1
Chun, KJ1
Harris, RR1
Mackenzie, IC1
Carlson, RP1
Gilman, SC1
Hodge, TG1
O'Neill-Davis, L1
Blazek, EM1
Lewis, AJ1
Wang, ZG2
Hagen, DO1
Mikat, EM2
Fuchs, JC2
McCann, RL1
Hagen, PO2
Cohen, SM1
Zenser, TV1
Murasaki, G1
Fukushima, S1
Mattammal, MB1
Rapp, NS1
Davis, BB1
Hackel, DB1
Carson, S1
Demling, R1
Esquivel, C1
Talken, L1
Tillman, P1
Schilderman, PA1
ten Vaarwerk, FJ1
Lutgerink, JT1
Van der Wurff, A1
ten Hoor, F1
Kleinjans, JC1
Hirko, MK1
McShannic, JR1
Schmidt, SP1
Sharp, WV1
Evancho, MM1
Sims, RL1
Siebert, JD1
Hårdhammar, PA1
Emanuelsson, HU1
Hofma, SH1
Albertsson, PA1
Verdouw, PD1
Boersma, E1
Stachura, J1
Konturek, JW1
Dembinski, A1
Domschke, W1
Harvey, R1
Bredenberg, CE1
Couper, L1
Himmelfarb, J1
Martínez, ME1
McPherson, RS1
Levin, B1
Glober, GA1
Mawatari, K1
Komori, K1
Kuma, S1
Okazaki, J1
Kawasaki, K1
Eguchi, D1
Itoh, H1
Onohara, T1
Sugimachi, K1
Samaniego, F1
Pati, S1
Karp, JE1
Prakash, O1
Bose, D1
Oblath, RW1
Buckley, FO1
Green, RM1
Schwartz, SI1
DeWeese, JA1
Jones, PM1
Weirich, EG1
Longauer, JK1
Kirkwood, AH1
Clowes, AW1
Karnovsky, MJ1
Graham, LM1
Brothers, TE1
Vincent, CK1
Burkel, WE1
Stanley, JC1
Landymore, RW2
MacAulay, MA1
Fris, J1
Yeager, RA1
Trune, DR1
Jacobson, S1
Connell, RS1
Galey, WT1
Shoemake, RG1
Vetto, RM1
Bush, HL2
Jakubowski, JA2
Sentissi, JM2
Quiñones-Baldrich, WJ1
Ziomek, S1
Henderson, T1
Moore, WS1
Meyer, RA1
McGinley, D1
Posalaky, Z1
Curl, GR1
Hayes, JA1
Deykin, D1
Bourassa, MG1
Fisher, LD1
Campeau, L1
Gillespie, MJ1
McConney, M1
Lespérance, J1
Fuster, V1
Chesebro, JJ1
MacAulay, M1
Sheridan, B1
Cameron, C1
Crean, GP1
Riede, UN1
Torhorst, J1
Rohr, HP1

Clinical Trials (15)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
PROlonging Dual Antiplatelet Treatment In Patients With Coronary Artery Disease After Graded Stent-induced Intimal Hyperplasia studY[NCT00611286]Phase 41,700 participants (Anticipated)Interventional2006-12-31Completed
Impact of Preoperative FFR on Arterial Bypass Graft Functionality: Towards a New CABG Paradigm[NCT02527044]120 participants (Anticipated)Interventional2015-11-30Active, not recruiting
Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial): Does Clopidogrel Prevent Saphenous Vein Graft Disease After Coronary Bypass?[NCT00228423]Phase 2113 participants (Actual)Interventional2006-05-31Completed
A Prospective Optical Coherence Tomography Study on Completeness of Strut Coverage and Vessel Wall Response at 3-6 and 9 Months Following Paclitaxel Eluting Stent Implantation in Multivessel Coronary Artery Disease[NCT00704145]Phase 430 participants (Anticipated)Interventional2007-11-30Completed
Qvanteq Bioactive Coronary Stent System First in Man (FIM) Clinical Investigation[NCT02176265]31 participants (Actual)Interventional2014-09-30Completed
Vessel Injury in Relation With Strut Thickness Assessed by OCT (VISTA): A Comparison of Vascular Injury Induced by a Polymer Free Sirolimus and Probucol Eluting Stent and a Biodegradable-polymer Biolimus-eluting Stent[NCT03026465]Phase 450 participants (Actual)Interventional2017-02-16Completed
In-Vivo Vascular Response of Sirolimus-,Paclitaxel- and Zotarolimus-Eluting Stents in Long Lesions Requiring Overlapping. A Prospective, Randomized, Controlled Study Using Optical Coherence Tomography[NCT00693030]Phase 477 participants (Anticipated)Interventional2006-08-31Recruiting
The Optical Coherence Tomography Drug Eluting Stent Investigation(OCTDESI)[NCT00776204]60 participants (Actual)Interventional2008-05-31Completed
Frequency Domain Imaging to Determine Stent Strut Coverage and Duration of Anti-Platelet Treatment After Endeavor Stent Placement[NCT01219894]0 participants (Actual)Observational2010-11-30Withdrawn (stopped due to Number of patients to meet individual IDE requirements was not obtained.)
Effect of TCFA on Neointimal Coverage After EXCEL Biodegradable Polymer-coated Sirolimus-eluting Stents Implantation at 9 Months Follow-up: Evaluated by Optical Coherence Tomography and Fractional Flow Reserve[NCT02384837]33 participants (Actual)Observational2014-12-31Completed
Optical Frequency Domain Imaging (OFDI) Determined Stent Strut Coverage and Plaque Morphology After RESOLUTE Stent Placement in Non-Insulin Dependent Diabetics Presenting With Acute Coronary Syndrome (ACS)[NCT01794949]8 participants (Actual)Interventional2013-09-30Completed
Value of Levonorgestrel-Releasing Intrauterine System (LNG-IUS) in the Fertility-preserving Treatment of Atypical Endometrial Hyperplasia and Early Endometrial Carcinoma[NCT03463252]Phase 2/Phase 3224 participants (Anticipated)Interventional2018-04-01Recruiting
Study of the Efficacy and Safety of Cilostazol in the Prevention of Ischemic Vascular Events in Diabetic Patients With Symptomatic Peripheral Artery Disease.[NCT02983214]Phase 4826 participants (Actual)Interventional2016-11-30Completed
Comparison of Platelet Inhibitory Effect With Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction Patients According to CYP2C19 Polymorphism[NCT00915733]Phase 480 participants (Actual)Interventional2009-05-31Completed
[NCT00000489]Phase 30 participants Interventional1973-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Major Adverse Coronary Events Within One Year Following Surgery

(NCT00228423)
Timeframe: 1 year

InterventionParticipants (Count of Participants)
75mg Clopidogrel4
Placebo5

Incidence of Major Bleeding Events Within One Year Following Surgery

(NCT00228423)
Timeframe: 1 year

InterventionParticipants (Count of Participants)
75mg Clopidogrel1
Placebo0

Vein Graft Angiographic Patency

Postoperative angiogram 12 months post-CABG (NCT00228423)
Timeframe: One year following surgery

Interventionpercentage (Number)
75mg Clopidogrel94.3
Placebo93.2

Vein Graft Intimal Area

IVUS imaging 12 months post-CABG, and the average intimal area in the proximal 40 mm of one vein graft per patient will be assessed (NCT00228423)
Timeframe: One year following surgery

Interventionmm (Mean)
75mg Clopidogrel4.1
Placebo4.5

Percent Stent Coverage

Assessment of vascular healing 6 months after Resolute Integrity placement in non-diabetic patients and patients with non-insulin dependent diabetes presenting with acute coronary syndrome (ACS) using optical frequency domain imaging (OFDI). Vascular healing will be measured by percent covered stents as determined by OFDI. A higher percentage of stent coverage indicates increased endothelial regrowth, which is an essential component for the maintenance of long-term luminal patency. (NCT01794949)
Timeframe: 6 months

,
InterventionParticipants (Count of Participants)
85% up to 90% stent coverage90% up to 95% stent coverage95% or greater percent stent coverage
NIDDM Patients Receiving the Resolute Stent010
Non-diabetic Patients Receiving the Resolute Stent131

Reviews

5 reviews available for aspirin and Hyperplasia

ArticleYear
Pathophysiology and Mechanisms of Saphenous Vein Graft Failure.
    Brazilian journal of cardiovascular surgery, 2022, 09-02, Volume: 37, Issue:Spec 1

    Topics: Aspirin; Graft Occlusion, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperpla

2022
The effect of prolonged aspirin therapy on experimental balloon-catheter arterial wall injury.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 1990, Volume: 3, Issue:1

    Topics: Animals; Aorta, Abdominal; Aspirin; Catheterization; Hyperplasia; Male; Rabbits

1990
Long-term fate of bypass grafts: the Coronary Artery Surgery Study (CASS) and Montreal Heart Institute experiences.
    Circulation, 1985, Volume: 72, Issue:6 Pt 2

    Topics: Animals; Aspirin; Clinical Trials as Topic; Coronary Artery Bypass; Dipyridamole; Follow-Up Studies;

1985
Aortocoronary artery vein-graft disease: experimental and clinical approach for the understanding of the role of platelets and platelet inhibitors.
    Circulation, 1985, Volume: 72, Issue:6 Pt 2

    Topics: Animals; Aspirin; Blood Platelets; Coronary Artery Bypass; Coronary Disease; Dipyridamole; Dogs; Gra

1985
Etiology of peptic ulcer.
    The Practitioner, 1974, Volume: 213, Issue:1273

    Topics: Anxiety Disorders; Aspirin; Bile Acids and Salts; Blood Group Antigens; Diet; Duodenal Ulcer; Female

1974

Trials

10 trials available for aspirin and Hyperplasia

ArticleYear
Impact of clinical presentation on ischaemic and bleeding outcomes in patients receiving 6- or 24-month duration of dual-antiplatelet therapy after stent implantation: a pre-specified analysis from the PRODIGY (Prolonging Dual-Antiplatelet Treatment After
    European heart journal, 2015, May-21, Volume: 36, Issue:20

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combinat

2015
Impact of proton pump inhibitors on clinical outcomes in patients treated with a 6- or 24-month dual-antiplatelet therapy duration: Insights from the PROlonging Dual-antiplatelet treatment after Grading stent-induced Intimal hyperplasia studY trial.
    American heart journal, 2016, Volume: 174

    Topics: Administration, Oral; Aged; Aspirin; Clopidogrel; Coronary Vessels; Drug Therapy, Combination; Elect

2016
Prolonged vs Short Duration of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention in Patients With or Without Peripheral Arterial Disease: A Subgroup Analysis of the PRODIGY Randomized Clinical Trial.
    JAMA cardiology, 2016, 10-01, Volume: 1, Issue:7

    Topics: Aged; Aspirin; Composite Resins; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans;

2016
Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) Trial.
    Circulation, 2010, Dec-21, Volume: 122, Issue:25

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Dr

2010
Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) Trial.
    Circulation, 2010, Dec-21, Volume: 122, Issue:25

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Dr

2010
Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) Trial.
    Circulation, 2010, Dec-21, Volume: 122, Issue:25

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Dr

2010
Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) Trial.
    Circulation, 2010, Dec-21, Volume: 122, Issue:25

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Dr

2010
A paclitaxel-eluting stent for the prevention of coronary restenosis.
    The New England journal of medicine, 2003, Apr-17, Volume: 348, Issue:16

    Topics: Angiogenesis Inhibitors; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography;

2003
Direct stenting versus direct stenting followed by centered beta-radiation with intravascular ultrasound-guided dosimetry and long-term anti-platelet treatment: results of a randomized trial: Beta-Radiation Investigation with Direct Stenting and Galileo i
    Journal of the American College of Cardiology, 2004, Aug-04, Volume: 44, Issue:3

    Topics: Aged; Aspirin; Brachytherapy; Clopidogrel; Coronary Angiography; Coronary Restenosis; Europe; Female

2004
Multicenter phase II study of fertility-sparing treatment with medroxyprogesterone acetate for endometrial carcinoma and atypical hyperplasia in young women.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Jul-01, Volume: 25, Issue:19

    Topics: Adult; Aspirin; Carcinoma; Disease-Free Survival; Endometrial Neoplasms; Endometrium; Female; Fertil

2007
Effect of cilostazol on in-stent neointimal hyperplasia after coronary artery stenting: a quantative coronary angiography and volumetric intravascular ultrasound study.
    Circulation journal : official journal of the Japanese Circulation Society, 2007, Volume: 71, Issue:11

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Vessels; Dr

2007
Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im
    Journal of the American College of Cardiology, 2008, Mar-25, Volume: 51, Issue:12

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Rest

2008
Long-term fate of bypass grafts: the Coronary Artery Surgery Study (CASS) and Montreal Heart Institute experiences.
    Circulation, 1985, Volume: 72, Issue:6 Pt 2

    Topics: Animals; Aspirin; Clinical Trials as Topic; Coronary Artery Bypass; Dipyridamole; Follow-Up Studies;

1985

Other Studies

44 other studies available for aspirin and Hyperplasia

ArticleYear
2(1H)-quinolinone derivatives as novel anti-arteriostenotic agents showing anti-thrombotic and anti-hyperplastic activities.
    Bioorganic & medicinal chemistry letters, 1998, Jun-16, Volume: 8, Issue:12

    Topics: Animals; Arteriosclerosis; Cilostazol; Hyperplasia; Platelet Aggregation Inhibitors; Quinolines; Qui

1998
Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2022, Volume: 33, Issue:9

    Topics: Animals; Apoptosis; Aspirin; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis, Ulcerative;

2022
Rabbit Elastase Aneurysm: Imaging and Histology Correlates for Inflammation and Healing.
    World neurosurgery, 2021, Volume: 148

    Topics: Animals; Aspirin; Carotid Artery Diseases; Carotid Artery, Common; Disease Models, Animal; Disease P

2021
Internal Carotid Artery Web as the Cause of Recurrent Cryptogenic Ischemic Stroke.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:5

    Topics: Adult; Aspirin; Atorvastatin; Biopsy; Brain Ischemia; Cardiovascular Agents; Carotid Artery Diseases

2018
Promoting endothelial recovery and reducing neointimal hyperplasia using sequential-like release of acetylsalicylic acid and paclitaxel-loaded biodegradable stents.
    International journal of nanomedicine, 2014, Volume: 9

    Topics: Absorbable Implants; Animals; Aorta, Abdominal; Aspirin; Biocompatible Materials; Calcium-Binding Pr

2014
Aspirin-triggered 15-epi-lipoxin A₄ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation.
    International journal of cardiology, 2015, Jan-20, Volume: 179

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Hyperplasia; Lipoxins; Mice; Mice

2015
Association between the efficacy of dual antiplatelet therapy and the development of in-stent neointimal hyperplasia in porcine coronary arteries.
    Coronary artery disease, 2008, Volume: 19, Issue:8

    Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Animals; Aspirin; Cell Proliferation; Clopido

2008
Lowering the dose of sirolimus, released from a nonpolymeric hydroxyapatite coated coronary stent, reduces signs of delayed healing.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Animals; Aspirin; Cardiovascular Agents; Clopidogrel; Coated Materia

2009
Dipyridamole plus aspirin and hemodialysis graft patency.
    The New England journal of medicine, 2009, Aug-13, Volume: 361, Issue:7

    Topics: Aspirin; Blood Vessel Prosthesis; Dipyridamole; Drug Therapy, Combination; Graft Occlusion, Vascular

2009
Letter by Gasparovic et al regarding article, "Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) trial".
    Circulation, 2011, Aug-09, Volume: 124, Issue:6

    Topics: Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Disease; Dr

2011
Letter by Bisdas et al regarding article, "Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) trial".
    Circulation, 2011, Aug-09, Volume: 124, Issue:6

    Topics: Aspirin; Biotransformation; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary

2011
Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection.
    Circulation research, 2004, Jun-11, Volume: 94, Issue:11

    Topics: Animals; Arteriosclerosis; Aspirin; Blood Vessel Prosthesis Implantation; Carotid Arteries; Disease

2004
Severe stenosis of anastomoses by using the symmetry aortic connector system.
    The Annals of thoracic surgery, 2004, Volume: 78, Issue:5

    Topics: Aged; Angina, Unstable; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Arter

2004
Chronic hyperplastic eosinophilic sinusitis as a predictor of aspirin-exacerbated respiratory disease.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2005, Volume: 94, Issue:6

    Topics: Adult; Aspirin; Asthma; Case-Control Studies; Chronic Disease; Cohort Studies; Drug Hypersensitivity

2005
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
    Circulation, 2007, May-08, Volume: 115, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coro

2007
Effect of external stents on prevention of intimal hyperplasia in a canine vein graft model.
    Chinese medical journal, 2007, Dec-20, Volume: 120, Issue:24

    Topics: Animals; Aspirin; Dogs; Femoral Vein; Hyperplasia; Stents; Tunica Intima; Ultrasonography, Doppler,

2007
Effects of aspirin on the development of Helicobacter pylori-induced gastric inflammation and heterotopic proliferative glands in Mongolian gerbils.
    Helicobacter, 2008, Volume: 13, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Aspirin; Choristoma; Dinoprostone; Epithelial Cells; G

2008
Effects of the anti-inflammatory agents indomethacin, metiamide and acetylsalicylic acid on the induction of hyperplasia in hamster cheek-pouch epithelium and ear epidermis.
    Journal of oral pathology, 1984, Volume: 13, Issue:2

    Topics: Animals; Aspirin; Cricetinae; Ear, External; Epidermis; Hyperplasia; Indomethacin; Mesocricetus; Met

1984
Effects of oral aspirin and oxaprozin on the development of lupus-like disease in MRL/1 mice.
    Journal of immunopharmacology, 1984, Volume: 6, Issue:1-2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Aspirin; Autoim

1984
[Intimal hyperplasia in aorta adjacent to small diameter Gore-Tex graft in monkey and its reduction by antiplatelet therapy].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1983, Volume: 21, Issue:12

    Topics: Animals; Aorta; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Hyperplasia; Macaca fascicularis;

1983
Aspirin and dipyridamole decrease intimal hyperplasia in experimental vein grafts.
    Annals of surgery, 1980, Volume: 191, Issue:2

    Topics: Animals; Aspirin; Carotid Arteries; Dipyridamole; Femoral Vein; Haplorhini; Hyperplasia; Iliac Arter

1980
Aspirin inhibition of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced lesions of the urinary bladder correlated with inhibition of metabolism by bladder prostaglandin endoperoxide synthetase.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Animals; Aspirin; Biotransformation; Cyclooxygenase Inhibitors; FANFT; Hyperplasia; Male; Neoplasms,

1981
Antiplatelet therapy reduces aortic intimal hyperplasia distal to small diameter vascular prostheses (PTFE) in nonhuman primates.
    Annals of surgery, 1982, Volume: 195, Issue:3

    Topics: Animals; Aorta, Abdominal; Aortic Diseases; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Dipyr

1982
Testing and treatment of arterial graft thrombosis.
    American journal of surgery, 1981, Volume: 142, Issue:1

    Topics: Animals; Arteries; Aspirin; Blood Vessel Prosthesis; Constriction, Pathologic; Disease Models, Anima

1981
Induction of oxidative DNA damage and early lesions in rat gastro-intestinal epithelium in relation to prostaglandin H synthase-mediated metabolism of butylated hydroxyanisole.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Aspirin; Biotransformation; Butylated Hydroxyanisole; Cell Div

1995
Pharmacologic modulation of intimal hyperplasia in canine vein interposition grafts.
    Journal of vascular surgery, 1993, Volume: 17, Issue:5

    Topics: Animals; Aspirin; Blood Vessel Prosthesis; Carotid Arteries; Cilazapril; Cyclosporine; Dogs; Female;

1993
Reduction in thrombotic events with heparin-coated Palmaz-Schatz stents in normal porcine coronary arteries.
    Circulation, 1996, Feb-01, Volume: 93, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Animals; Aspirin; Coronary Angiography; Coronary Thrombosis; Coronar

1996
Growth markers in the human gastric mucosa during adaptation to continued aspirin administration.
    Journal of clinical gastroenterology, 1996, Volume: 22, Issue:4

    Topics: Adaptation, Physiological; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Drug

1996
Aspirin enhances platelet-derived growth factor-induced vascular smooth muscle cell proliferation.
    Journal of vascular surgery, 1997, Volume: 25, Issue:4

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aorta; Arachidonate 12-Lipoxygenase; Arachidonic Acids;

1997
A case-control study of dietary intake and other lifestyle risk factors for hyperplastic polyps.
    Gastroenterology, 1997, Volume: 113, Issue:2

    Topics: Adenoma; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Mass Index;

1997
The inhibition of canine vein graft intimal thickening using a newly developed antiplatelet agent.
    The Journal of cardiovascular surgery, 1997, Volume: 38, Issue:4

    Topics: Animals; Aspirin; Blood Flow Velocity; Bromodeoxyuridine; Cell Division; Dogs; Fatty Acids, Monounsa

1997
Human herpesvirus 8 K1-associated nuclear factor-kappa B-dependent promoter activity: role in Kaposi's sarcoma inflammation?
    Journal of the National Cancer Institute. Monographs, 2001, Issue:28

    Topics: Amino Acid Motifs; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chlorocebus aethiops;

2001
Prevention of platelet aggregation and adherence to prosthetic vascular grafts by aspirin and dipyridamole.
    Surgery, 1978, Volume: 84, Issue:1

    Topics: Animals; Aspirin; Blood Vessel Prosthesis; Dipyridamole; Dogs; Femoral Artery; Hyperplasia; Platelet

1978
Complete dentures and the associated soft tissues.
    The Journal of the Kansas State Dental Association, 1977, Volume: 61, Issue:1

    Topics: Aspirin; Candidiasis; Cheilitis; Denture, Complete; Diagnosis, Oral; Foreign Bodies; Hyperplasia; Ke

1977
Epidermal antihyperplastic effects of contact antiphlogistics.
    Dermatologica, 1978, Volume: 156, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bufexamac; Fluocinolone Acetonide; Guinea Pigs; Hydrocor

1978
Failure of certain antiplatelet drugs to affect myointimal thickening following arterial endothelial injury in the rat.
    Laboratory investigation; a journal of technical methods and pathology, 1977, Volume: 36, Issue:4

    Topics: Adenosine Diphosphate; Air; Animals; Aspirin; Blood Coagulation Tests; Blood Platelets; Carotid Arte

1977
The role of an endothelial cell lining in limiting distal anastomotic intimal hyperplasia of 4-mm-I.D. Dacron grafts in a canine model.
    Journal of biomedical materials research, 1991, Volume: 25, Issue:4

    Topics: Animals; Aorta, Abdominal; Aspirin; Blood Vessel Prosthesis; Dogs; Endothelium, Vascular; Hyperplasi

1991
Effect of aspirin on intimal hyperplasia and cholesterol uptake in experimental bypass grafts.
    The Canadian journal of cardiology, 1991, Volume: 7, Issue:2

    Topics: Animals; Arteriosclerosis; Aspirin; Cell Division; Cholesterol; Dogs; Graft Occlusion, Vascular; Hyp

1991
Early healing after carotid endarterectomy: effect of high- and low-dose aspirin on thrombosis and early neointimal hyperplasia in a nonhuman primate model.
    Journal of vascular surgery, 1988, Volume: 7, Issue:2

    Topics: Animals; Aspirin; Bleeding Time; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Endar

1988
Patency and intimal hyperplasia: the effect of aspirin on small arterial anastomosis.
    Annals of vascular surgery, 1988, Volume: 2, Issue:1

    Topics: Anastomosis, Surgical; Animals; Aspirin; Female; Hyperplasia; Iliac Artery; Platelet Adhesiveness; P

1988
Effects of aspirin on tight junction structure of the canine gastric mucosa.
    Gastroenterology, 1986, Volume: 91, Issue:2

    Topics: Animals; Aspirin; Cardia; Dogs; Female; Freeze Fracturing; Gastric Fundus; Gastric Mucosa; Hyperplas

1986
Neointimal hyperplasia occurring after carotid endarterectomy in a canine model: effect of endothelial cell seeding vs. perioperative aspirin.
    Journal of vascular surgery, 1987, Volume: 5, Issue:1

    Topics: Animals; Aspirin; Carotid Arteries; Dogs; Endarterectomy; Hyperplasia; Models, Cardiovascular; Plate

1987
Comparison of cod-liver oil and aspirin-dipyridamole for the prevention of intimal hyperplasia in autologous vein grafts.
    The Annals of thoracic surgery, 1986, Volume: 41, Issue:1

    Topics: Animals; Aspirin; Blood Platelets; Cod Liver Oil; Dietary Fats; Dipyridamole; Dogs; Drug Combination

1986
Focal proliferation of the smooth endoplasmic reticulum in the cells of the straight part of the proximal kidney tubule.
    Pathologia Europaea, 1973, Volume: 8, Issue:3

    Topics: Animals; Aspirin; Cell Aggregation; Cytoplasmic Granules; Endoplasmic Reticulum; Hydrocarbons, Bromi

1973