Page last updated: 2024-10-23

aspirin and Huntington Disease

aspirin has been researched along with Huntington Disease in 2 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Cho, IK1
Easley, CA1
Chan, AWS1
Norflus, F1
Nanje, A1
Gutekunst, CA1
Shi, G1
Cohen, J1
Bejarano, M1
Fox, J1
Ferrante, RJ1
Hersch, SM1

Other Studies

2 other studies available for aspirin and Huntington Disease

ArticleYear
Suppression of trinucleotide repeat expansion in spermatogenic cells in Huntington's disease.
    Journal of assisted reproduction and genetics, 2022, Volume: 39, Issue:10

    Topics: Aspirin; Cytarabine; Germ Cells; Humans; Huntington Disease; Male; Proliferating Cell Nuclear Antige

2022
Anti-inflammatory treatment with acetylsalicylate or rofecoxib is not neuroprotective in Huntington's disease transgenic mice.
    Neurobiology of disease, 2004, Volume: 17, Issue:2

    Topics: Acoustic Stimulation; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; As

2004