aspirin has been researched along with Hormone-Dependent Neoplasms in 5 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Aspirin use post-diagnosis may modify components of the PI3K pathway, including AKT and mTOR, and has been associated with lower risk of breast cancer recurrence and mortality." | 7.96 | Different associations of tumor PIK3CA mutations and clinical outcomes according to aspirin use among women with metastatic hormone receptor positive breast cancer. ( Armstrong, K; Bardia, A; Chan, AT; He, W; Iafrate, AJ; Kumar, NP; McCarthy, AM; Moy, B; Regan, S; Welch, M, 2020) |
| "Among these breast cancers those that are estrogen-responsive respond well to existing therapeutic regimens while estrogen non-responsive cancers metastasize widely, demonstrate a high relapse rate, and respond poorly to therapy." | 5.31 | Beta-adrenergic and arachidonic acid-mediated growth regulation of human breast cancer cell lines. ( Cakir, Y; Plummer, HK; Schuller, HM; Tithof, PK, 2002) |
| " Aspirin use post-diagnosis may modify components of the PI3K pathway, including AKT and mTOR, and has been associated with lower risk of breast cancer recurrence and mortality." | 3.96 | Different associations of tumor PIK3CA mutations and clinical outcomes according to aspirin use among women with metastatic hormone receptor positive breast cancer. ( Armstrong, K; Bardia, A; Chan, AT; He, W; Iafrate, AJ; Kumar, NP; McCarthy, AM; Moy, B; Regan, S; Welch, M, 2020) |
| "Breast cancer is the most common cancer in women worldwide." | 2.52 | Update on breast cancer risk prediction and prevention. ( Cuzick, J; Sestak, I, 2015) |
| "Among these breast cancers those that are estrogen-responsive respond well to existing therapeutic regimens while estrogen non-responsive cancers metastasize widely, demonstrate a high relapse rate, and respond poorly to therapy." | 1.31 | Beta-adrenergic and arachidonic acid-mediated growth regulation of human breast cancer cell lines. ( Cakir, Y; Plummer, HK; Schuller, HM; Tithof, PK, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wiglenda, T | 1 |
| Ott, I | 1 |
| Kircher, B | 1 |
| Schumacher, P | 1 |
| Schuster, D | 1 |
| Langer, T | 1 |
| Gust, R | 1 |
| McCarthy, AM | 1 |
| Kumar, NP | 1 |
| He, W | 1 |
| Regan, S | 1 |
| Welch, M | 1 |
| Moy, B | 1 |
| Iafrate, AJ | 1 |
| Chan, AT | 1 |
| Bardia, A | 1 |
| Armstrong, K | 1 |
| Sestak, I | 1 |
| Cuzick, J | 1 |
| Fedoruk, MN | 1 |
| Giménez-Bonafé, P | 1 |
| Guns, ES | 1 |
| Mayer, LD | 1 |
| Nelson, CC | 1 |
| Cakir, Y | 1 |
| Plummer, HK | 1 |
| Tithof, PK | 1 |
| Schuller, HM | 1 |
1 review available for aspirin and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Update on breast cancer risk prediction and prevention.
Topics: Age of Onset; Aromatase Inhibitors; Aspirin; Biomarkers, Tumor; Breast Neoplasms; Diphosphonates; Fe | 2015 |
4 other studies available for aspirin and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Synthesis and pharmacological evaluation of 1H-imidazoles as ligands for the estrogen receptor and cytotoxic inhibitors of the cyclooxygenase.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Humans; Imid | 2005 |
Different associations of tumor PIK3CA mutations and clinical outcomes according to aspirin use among women with metastatic hormone receptor positive breast cancer.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Aspi | 2020 |
P-glycoprotein increases the efflux of the androgen dihydrotestosterone and reduces androgen responsive gene activity in prostate tumor cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; ATP Binding Cassette Transporter, Subfamily B, Mem | 2004 |
Beta-adrenergic and arachidonic acid-mediated growth regulation of human breast cancer cell lines.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Arachidonate 5-Lipoxygenase; Arachidonic Acid | 2002 |