Page last updated: 2024-10-23

aspirin and Hip Fractures

aspirin has been researched along with Hip Fractures in 56 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Hip Fractures: Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).

Research Excerpts

ExcerptRelevanceReference
"To evaluates the efficacy and safety of rivaroxaban versus aspirin in prevention of venous thromboembolism (VTE) following total hip (THA) or knee arthroplasty (TKA) or hip fracture surgery."9.12Rivaroxaban versus aspirin in prevention of venous thromboembolism following total joint arthroplasty or hip fracture surgery: a meta-analysis. ( Dai, Z; Hu, B; Hu, M; Jiang, L; Tang, H; Yu, J, 2021)
"Among the patients with hip fracture, allocation to aspirin produced proportional reductions in pulmonary embolism of 43% (95% CI 18-60; p=0."9.09Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial. ( , 2000)
"The study objective was to determine the relative efficacy and safety of a low-molecular-weight heparinoid (Orgaran) compared with aspirin for the prevention of postoperative venous thromboembolism in patients undergoing surgery for fractured hips."9.08Low-molecular-weight heparinoid orgaran is more effective than aspirin in the prevention of venous thromboembolism after surgery for hip fracture. ( Geerts, WH; Gent, M; Ginsberg, JS; Hirsh, J; Jay, RM; Leclerc, J; Levine, MN; Neemeh, JA; Powers, PJ; Turpie, AG, 1996)
"To compare venous thromboembolism (VTE) and bleeding rates in adult patients receiving aspirin versus anticoagulants after major lower extremity orthopedic surgery."8.90Aspirin versus anticoagulation for prevention of venous thromboembolism major lower extremity orthopedic surgery: a systematic review and meta-analysis. ( Chiang, WH; Drescher, FS; Larson, RJ; Lee, A; Morrison, DH; Sirovich, BE, 2014)
"To compare the efficacy and safety of aspirin with rivaroxaban following treatment with enoxaparin for prevention of venous thromboembolism (VTE) after hip fracture surgery (HFS)."7.91Comparison of the Efficacy and Safety of Aspirin and Rivaroxaban Following Enoxaparin Treatment for Prevention of Venous Thromboembolism after Hip Fracture Surgery. ( Huang, Q; Shen, B; Si, HB; Xing, SX; Zeng, Y; Zhou, ZK, 2019)
"In patients with extremity fractures that had been treated operatively or with any pelvic or acetabular fracture, thromboprophylaxis with aspirin was noninferior to low-molecular-weight heparin in preventing death and was associated with low incidences of deep-vein thrombosis and pulmonary embolism and low 90-day mortality."5.69Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture. ( Bosse, MJ; Carlini, AR; Castillo, RC; Degani, Y; Firoozabadi, R; Frey, KP; Goldhaber, SZ; Haut, ER; Marvel, D; O'Hara, NN; O'Toole, RV; Obremskey, W; Scharfstein, DO; Slobogean, GP; Stein, DM; Sudini, K; Taylor, TJ, 2023)
"Aspirin was not associated with a significantly higher risk of hidden blood loss (aspirin group; median 598 mL [410-783 mL] vs control group; median 556 ml [321-741 mL], p = 0."5.62Retrospective high volume comparative study suggests that patients on aspirin could have immediate surgery for hip fractures without significant blood loss. ( Ito, Y; Kanazawa, T; Ohmori, T; Tada, K; Toda, K; Yagata, Y, 2021)
"To evaluates the efficacy and safety of rivaroxaban versus aspirin in prevention of venous thromboembolism (VTE) following total hip (THA) or knee arthroplasty (TKA) or hip fracture surgery."5.12Rivaroxaban versus aspirin in prevention of venous thromboembolism following total joint arthroplasty or hip fracture surgery: a meta-analysis. ( Dai, Z; Hu, B; Hu, M; Jiang, L; Tang, H; Yu, J, 2021)
"Among the patients with hip fracture, allocation to aspirin produced proportional reductions in pulmonary embolism of 43% (95% CI 18-60; p=0."5.09Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial. ( , 2000)
"The study objective was to determine the relative efficacy and safety of a low-molecular-weight heparinoid (Orgaran) compared with aspirin for the prevention of postoperative venous thromboembolism in patients undergoing surgery for fractured hips."5.08Low-molecular-weight heparinoid orgaran is more effective than aspirin in the prevention of venous thromboembolism after surgery for hip fracture. ( Geerts, WH; Gent, M; Ginsberg, JS; Hirsh, J; Jay, RM; Leclerc, J; Levine, MN; Neemeh, JA; Powers, PJ; Turpie, AG, 1996)
"To compare venous thromboembolism (VTE) and bleeding rates in adult patients receiving aspirin versus anticoagulants after major lower extremity orthopedic surgery."4.90Aspirin versus anticoagulation for prevention of venous thromboembolism major lower extremity orthopedic surgery: a systematic review and meta-analysis. ( Chiang, WH; Drescher, FS; Larson, RJ; Lee, A; Morrison, DH; Sirovich, BE, 2014)
"Bone fractures are a global public health concern, yet no thorough investigation of low-dose aspirin usage to prevent fractures in the elderly has been conducted."4.31NHANES cross sectional study of aspirin and fractures in the elderly. ( Abbas, KS; Abouainain, Y; Ahmad, EMS; Albuni, MK; Battikh, E; El-Sakka, AA; Elkalagi, NKH; Hafez, W; Lee, KY; Rakab, A; Sawaf, B; Swed, S, 2023)
"One thousand four hundred forty-two geriatric (ages 60-105 years) patients undergoing isolated primary intramedullary fixation of nonpathologic extracapsular hip fractures from 2009 to 2018 including 657 taking an antiplatelet drug alone (including aspirin), 99 taking warfarin alone, 37 taking a direct oral anticoagulant (DOAC) alone, 59 taking an antiplatelet drug and an anticoagulant, and 590 taking neither."4.31Full Reversal of Anticoagulants Before Cephalomedullary Fixation of Geriatric Hip Fractures May Not Be Necessary. ( Ahn, J; Hake, ME; Maturana, C; Perdue, AM; Schaffer, NE; Singh, M, 2023)
" The incidence of VTE and hematoma formation was evaluated and compared between patients who received aspirin versus enoxaparin or heparin."4.12Does Aspirin Provide Adequate Chemoprophylaxis for Venous Thromboembolic Events in Operative Pelvic and Acetabular Fractures? ( Du, JY; Metcalf, KB; Ochenjele, G, 2022)
"To compare the efficacy and safety of aspirin with rivaroxaban following treatment with enoxaparin for prevention of venous thromboembolism (VTE) after hip fracture surgery (HFS)."3.91Comparison of the Efficacy and Safety of Aspirin and Rivaroxaban Following Enoxaparin Treatment for Prevention of Venous Thromboembolism after Hip Fracture Surgery. ( Huang, Q; Shen, B; Si, HB; Xing, SX; Zeng, Y; Zhou, ZK, 2019)
" The case was complicated due to a history of aspirin usage, marked obesity, and thrombocytopenia."3.67Femoral artery laceration complicating an intertrochanteric hip fracture: a multi-disciplinary therapeutic problem. ( Chmell, S; Haid, S; Milewski, S; Moss, GD; Pillars, JR, 1985)
"Proximal vein thrombosis or pulmonary embolism occurred in 6 patients (9."2.66A randomized trial of less intense postoperative warfarin or aspirin therapy in the prevention of venous thromboembolism after surgery for fractured hip. ( Gent, M; Hirsh, J; Jay, RM; Julian, DH; Levine, M; Powers, PJ; Turpie, AG, 1989)
" The purpose of this study is to quantify the complication rate associated with FICB in patients who are actively taking prescribed anticoagulant and/or antiplatelet medications prior to injury and identify factors that may predispose patients to an adverse event."1.72The safety of continuous fascia iliaca block in patients with hip fracture taking pre-injury anticoagulant and/or antiplatelet medications. ( Barletta, JF; Dzandu, JK; Mangram, AJ; Montanarella, PD; Prokuski, LJ; Shirah, GR; Sucher, JF, 2022)
"Aspirin was not associated with a significantly higher risk of hidden blood loss (aspirin group; median 598 mL [410-783 mL] vs control group; median 556 ml [321-741 mL], p = 0."1.62Retrospective high volume comparative study suggests that patients on aspirin could have immediate surgery for hip fractures without significant blood loss. ( Ito, Y; Kanazawa, T; Ohmori, T; Tada, K; Toda, K; Yagata, Y, 2021)
"The current rates of deep vein thrombosis (DVT) and pulmonary embolism (PE) at our institution following hip or knee arthroplasty or hip fracture surgery are 1."1.56Incidence of venous thromboembolism after total hip, total knee and hip fracture surgery at Waitemata District Health Board following a peer-reviewed audit. ( Andrew, P; Farrington, B; Lawes, CM; Merriman, E; Millar, JS; Misur, P; Walker, M, 2020)
"The rate of postoperative complications has significantly increased annually only in HFS: VTE (P=0."1.46Trends of thromboprophylaxis and complications after major lower limb orthopaedic surgeries in Korea: National Health Insurance Claim Data. ( Ahn, H; Kim, S; Park, JH; Shin, SA; Won, CW, 2017)
" It appears from this study that in these cases prophylaxis against venous thromboembolism using aspirin in a dosage of 600 mg bid is ineffective."1.26Aspirin prophylaxis of venous thromboembolic disease following fracture of the upper femur. ( Channon, GM; Wiley, AM, 1979)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19906 (10.71)18.7374
1990's7 (12.50)18.2507
2000's19 (33.93)29.6817
2010's13 (23.21)24.3611
2020's11 (19.64)2.80

Authors

AuthorsStudies
Metcalf, KB1
Du, JY1
Ochenjele, G1
Sucher, JF1
Barletta, JF1
Shirah, GR1
Prokuski, LJ1
Montanarella, PD1
Dzandu, JK1
Mangram, AJ1
O'Toole, RV1
Stein, DM1
O'Hara, NN1
Frey, KP1
Taylor, TJ1
Scharfstein, DO1
Carlini, AR1
Sudini, K1
Degani, Y1
Slobogean, GP1
Haut, ER1
Obremskey, W1
Firoozabadi, R1
Bosse, MJ1
Goldhaber, SZ1
Marvel, D1
Castillo, RC1
Swed, S1
El-Sakka, AA1
Abouainain, Y1
Lee, KY1
Sawaf, B1
Albuni, MK1
Battikh, E1
Ahmad, EMS1
Elkalagi, NKH1
Abbas, KS1
Hafez, W1
Rakab, A1
Maturana, C1
Singh, M1
Perdue, AM1
Ahn, J1
Hake, ME1
Schaffer, NE1
Poacher, AT1
Hoskins, HC1
Protty, MB1
Pettit, R1
Johansen, A1
Huang, Q1
Xing, SX1
Zeng, Y1
Si, HB1
Zhou, ZK1
Shen, B1
Sugiyama, T1
Millar, JS1
Lawes, CM1
Farrington, B1
Andrew, P1
Misur, P1
Merriman, E1
Walker, M1
Ohmori, T1
Toda, K1
Kanazawa, T1
Tada, K1
Yagata, Y1
Ito, Y1
Hu, B1
Jiang, L1
Tang, H1
Hu, M1
Yu, J1
Dai, Z1
Wang, R1
Wang, X1
Tong, P1
Kim, S1
Ahn, H1
Shin, SA1
Park, JH1
Won, CW1
Lin, SY1
Huang, HT1
Chou, SH1
Ho, CJ1
Liu, ZM1
Chen, CH1
Lu, CC1
Drescher, FS1
Sirovich, BE1
Lee, A1
Morrison, DH1
Chiang, WH1
Larson, RJ1
Sood, A1
Trinh, QD1
Li, T1
Lv, M1
Li, Q1
Lowe, G1
Estilita, J1
Alonso, FM1
Brasil, JS1
Baptista, MS1
Voelker, R1
Struijk-Mulder, MC1
Ettema, HB1
Verheyen, CC1
Büller, HR1
Sobieraj-Teague, M1
Eikelboom, JW1
Hirsh, J3
Chechik, O1
Thein, R1
Fichman, G1
Haim, A1
Tov, TB1
Steinberg, EL1
Scholl, S1
Dellon, ES1
Shaheen, NJ1
Kragh, AM1
Waldén, M1
Apelqvist, A1
Wagner, P1
Atroshi, I1
Ji, HM1
Lee, YK1
Ha, YC1
Kim, KC1
Koo, KH1
Collinge, CA1
Kelly, KC1
Little, B1
Weaver, T1
Schuster, RD1
Wordsworth, DR1
Halsey, T1
Griffiths, R1
Parker, MJ1
Kennedy, MT1
Roche, S1
Fleming, SM1
Lenehan, B1
Curtin, W1
Colwell, CW1
Grant, PJ1
Jaffer, AK1
Jeong, GK1
Gruson, KI1
Egol, KA1
Aharonoff, GB1
Karp, AH1
Zuckerman, JD2
Koval, KJ1
Harty, JA1
McKenna, P1
Moloney, D1
D'Souza, L1
Masterson, E1
Purushothaman, B1
Alho, A1
Stangeland, L1
Røttingen, J1
Wiig, JN1
Monreal, M1
Lafoz, E1
Roca, J1
Granero, X1
Soler, J1
Salazar, X1
Olazabal, A1
Bergqvist, D1
Feldman, DS1
Walters, I1
Sakales, SR1
Warwick, DJ1
Gent, M2
Ginsberg, JS1
Powers, PJ2
Levine, MN1
Geerts, WH1
Jay, RM2
Leclerc, J1
Neemeh, JA1
Turpie, AG2
Bauer, DC1
Orwoll, ES1
Fox, KM1
Vogt, TM1
Lane, NE1
Hochberg, MC1
Stone, K1
Nevitt, MC1
Nettleman, MD1
Alsip, J1
Schrader, M1
Schulte, M1
Sors, H1
Meyer, G1
Henley, E1
Mahé, I1
Bergmann, JF1
Mahé, E1
Caulin, C1
Parker, M1
Thomas, DP2
Grace, DL1
McCahill, JP1
Carrington, RW1
Skinner, JA1
Channon, GM1
Wiley, AM1
Yett, HS1
Skillman, JJ1
Salzman, EW1
Orthner, E1
Hertz, H1
Kwasny, O1
Maier, R1
Zekert, F1
Schemper, M1
Höfer, R1
Bergmann, H1
Havlick, E1
Wohlzogen, FX1
Pini, M1
Spadini, E1
Carluccio, L1
Giovanardi, C1
Magnani, E1
Ugolotti, U1
Uggeri, E1
Julian, DH1
Levine, M1
Moss, GD1
Chmell, S1
Pillars, JR1
Haid, S1
Milewski, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Different Approach to Preventing Thrombosis (ADAPT): A Randomized Controlled Trial Comparing Low Molecular Weight Heparin to Acetylsalicylic Acid in Orthopedic Trauma Patients[NCT02774265]Phase 3329 participants (Actual)Interventional2016-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Deep Venous Thromboembolism

DVT and how the diagnosis was made will be recorded. The number of events in participants in each arm will be compared to evaluate efficacy. (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID5
VTE Prophylaxis With Aspirin 81mg BID9

Number of Participants With Pulmonary Embolism Events

Bases on imaging obtained for symptoms. (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID6
VTE Prophylaxis With Aspirin 81mg BID2

Number of Participants With Treatment-related Bleeding Events as Assessed by the Need for Blood Transfusions and Procedures for Bleeding Complications After Initiation of the Study Medication.

Includes a greater than 2g/dL drop in hemoglobin, blood transfusion, hematoma evacuation, re-operation for a deep surgical site infection or minor procedure for bleeding and GI bleed (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID52
VTE Prophylaxis With Aspirin 81mg BID53

Reviews

5 reviews available for aspirin and Hip Fractures

ArticleYear
Rivaroxaban versus aspirin in prevention of venous thromboembolism following total joint arthroplasty or hip fracture surgery: a meta-analysis.
    Journal of orthopaedic surgery and research, 2021, Feb-13, Volume: 16, Issue:1

    Topics: Aged; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Female; Fracture Fix

2021
Aspirin versus anticoagulation for prevention of venous thromboembolism major lower extremity orthopedic surgery: a systematic review and meta-analysis.
    Journal of hospital medicine, 2014, Volume: 9, Issue:9

    Topics: Aged; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Fema

2014
Comparing consensus guidelines on thromboprophylaxis in orthopedic surgery.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:4

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgical; Cast

2010
When should prophylactic anticoagulation begin after a hip fracture?
    Cleveland Clinic journal of medicine, 2006, Volume: 73, Issue:9

    Topics: Anticoagulants; Aspirin; Chemoprevention; Heparin; Hip Fractures; Humans; Risk Assessment; Risk Fact

2006
Current concepts in venous thromboembolism and major lower limb orthopaedic surgery.
    International journal of clinical practice, 2002, Volume: 56, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement; Aspirin; Heparin, Low-Molecular-

2002

Trials

13 trials available for aspirin and Hip Fractures

ArticleYear
Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture.
    The New England journal of medicine, 2023, 01-19, Volume: 388, Issue:3

    Topics: Adult; Anticoagulants; Aspirin; Chemoprevention; Extremities; Fractures, Bone; Hemorrhage; Heparin,

2023
[Comprehensive prophylaxis for deep venous thrombosis after proximal femur fractures in geriatric patients].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2008, Volume: 22, Issue:4

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Combined Modality Therapy; Female; Femoral Neck Fr

2008
Prophylaxis of venous thromboembolism by aspirin, warfarin and heparin in patients with hip fracture. A prospective clinical study with cost-benefit analysis.
    Annales chirurgiae et gynaecologiae, 1984, Volume: 73, Issue:4

    Topics: Adult; Aspirin; Cost-Benefit Analysis; Female; Heparin; Hip Fractures; Humans; Male; Prospective Stu

1984
Platelet count, antiplatelet therapy and pulmonary embolism--a prospective study in patients with hip surgery.
    Thrombosis and haemostasis, 1995, Volume: 73, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage

1995
Antiplatelet therapy to prevent thrombosis after hip fracture.
    The Journal of bone and joint surgery. British volume, 1995, Volume: 77, Issue:1

    Topics: Aged; Aspirin; Drug Interactions; Heparin; Hip Fractures; Humans; Platelet Aggregation Inhibitors; P

1995
Low-molecular-weight heparinoid orgaran is more effective than aspirin in the prevention of venous thromboembolism after surgery for hip fracture.
    Circulation, 1996, Jan-01, Volume: 93, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Chondroitin Sulfates;

1996
Aspirin and NSAID use in older women: effect on bone mineral density and fracture risk. Study of Osteoporotic Fractures Research Group.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:1

    Topics: Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Density; Female; Fractures, Bo

1996
Place of aspirin in prophylaxis of venous thromboembolism.
    Lancet (London, England), 2000, Apr-15, Volume: 355, Issue:9212

    Topics: Arthroplasty, Replacement, Hip; Aspirin; Dose-Response Relationship, Drug; Hip Fractures; Humans; Pl

2000
Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial.
    Lancet (London, England), 2000, Apr-15, Volume: 355, Issue:9212

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Aspirin; Cause of Death; Dose-Response Rela

2000
The hazards of aspirin plus heparin.
    The New England journal of medicine, 1978, May-11, Volume: 298, Issue:19

    Topics: Aspirin; Drug Therapy, Combination; Hemorrhage; Heparin; Hip Fractures; Humans; Thrombophlebitis; Wa

1978
[Prevention of thromboembolism in para-articular femoral fractures of the hip--results of a prospective randomized study of heparin-DHE and ASS-DHE].
    Unfallchirurgie, 1990, Volume: 16, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Bone Screws; Cause of Death; Dihydroergotamine; Drug Combinations;

1990
Dextran/aspirin versus heparin/dihydroergotamine in preventing thrombosis after hip fractures.
    The Journal of bone and joint surgery. British volume, 1985, Volume: 67, Issue:2

    Topics: Aged; Aspirin; Clinical Trials as Topic; Dextrans; Dihydroergotamine; Double-Blind Method; Drug Ther

1985
A randomized trial of less intense postoperative warfarin or aspirin therapy in the prevention of venous thromboembolism after surgery for fractured hip.
    Archives of internal medicine, 1989, Volume: 149, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clinical Trials as Topic; Female; Follow-Up Studies; Hemorr

1989

Other Studies

38 other studies available for aspirin and Hip Fractures

ArticleYear
Does Aspirin Provide Adequate Chemoprophylaxis for Venous Thromboembolic Events in Operative Pelvic and Acetabular Fractures?
    The Iowa orthopaedic journal, 2022, Volume: 42, Issue:1

    Topics: Anticoagulants; Aspirin; Chemoprevention; Enoxaparin; Hematoma; Heparin; Hip Fractures; Humans; Pelv

2022
The safety of continuous fascia iliaca block in patients with hip fracture taking pre-injury anticoagulant and/or antiplatelet medications.
    American journal of surgery, 2022, Volume: 224, Issue:6

    Topics: Aged; Aged, 80 and over; Aspirin; Hip Fractures; Humans; Nerve Block; Platelet Aggregation Inhibitor

2022
NHANES cross sectional study of aspirin and fractures in the elderly.
    Scientific reports, 2023, 02-01, Volume: 13, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Bone Density; Cross-Sectional Studies; Female; Fractures, Bone; Hi

2023
Full Reversal of Anticoagulants Before Cephalomedullary Fixation of Geriatric Hip Fractures May Not Be Necessary.
    Journal of orthopaedic trauma, 2023, 09-01, Volume: 37, Issue:9

    Topics: Aged; Anticoagulants; Aspirin; Blood Loss, Surgical; Cohort Studies; Hip Fractures; Humans; Platelet

2023
The impact of adopting low-molecular-weight heparin in place of aspirin as routine thromboprophylaxis for patients with hip fracture.
    Postgraduate medical journal, 2023, Jun-15, Volume: 99, Issue:1172

    Topics: Anticoagulants; Aspirin; Heparin, Low-Molecular-Weight; Hip Fractures; Humans; Postoperative Complic

2023
Comparison of the Efficacy and Safety of Aspirin and Rivaroxaban Following Enoxaparin Treatment for Prevention of Venous Thromboembolism after Hip Fracture Surgery.
    Orthopaedic surgery, 2019, Volume: 11, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Drug Ther

2019
Proton Pump Inhibitor Therapy and Fracture Risk: Discrepancy of Results Between Observational and Interventional Studies.
    Gastroenterology, 2020, Volume: 158, Issue:4

    Topics: Aspirin; Hip Fractures; Humans; Proton Pump Inhibitors; Research; Rivaroxaban

2020
Incidence of venous thromboembolism after total hip, total knee and hip fracture surgery at Waitemata District Health Board following a peer-reviewed audit.
    The New Zealand medical journal, 2020, 03-13, Volume: 133, Issue:1511

    Topics: Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement,

2020
Retrospective high volume comparative study suggests that patients on aspirin could have immediate surgery for hip fractures without significant blood loss.
    International orthopaedics, 2021, Volume: 45, Issue:3

    Topics: Aged; Aspirin; Blood Loss, Surgical; Hip Fractures; Humans; Platelet Aggregation Inhibitors; Retrosp

2021
Comment on "Retrospective high volume comparative study suggests that patients on aspirin could have immediate surgery for hip fractures without significant blood loss".
    International orthopaedics, 2021, Volume: 45, Issue:8

    Topics: Aspirin; Hip Fractures; Humans; Platelet Aggregation Inhibitors; Retrospective Studies

2021
Trends of thromboprophylaxis and complications after major lower limb orthopaedic surgeries in Korea: National Health Insurance Claim Data.
    Thrombosis research, 2017, Volume: 155

    Topics: Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement,

2017
The Safety of Continuing Antiplatelet Medication Among Elderly Patients Undergoing Urgent Hip Fracture Surgery.
    Orthopedics, 2019, Sep-01, Volume: 42, Issue:5

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Transfusion; Dipyridamole; Drug Therap

2019
Perioperative aspirin: to give or not to give?
    BJU international, 2014, Volume: 114, Issue:3

    Topics: Aspirin; Blood Transfusion; Coronary Artery Bypass; Coronary Disease; Female; Fibrinolytic Agents; H

2014
Thromboprophylaxis for patients at high risk of VTE.
    Lancet (London, England), 2008, Sep-20, Volume: 372, Issue:9643

    Topics: Anticoagulants; Aspirin; Heparin; Hip Fractures; Humans; Practice Guidelines as Topic; Pulmonary Emb

2008
[Intradural block in essential thrombocytosis].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:1

    Topics: Aged, 80 and over; Anesthesia, Spinal; Aspirin; Female; Fracture Fixation, Internal; Hematoma, Epidu

2009
Common drugs can harm elderly patients.
    JAMA, 2009, Aug-12, Volume: 302, Issue:6

    Topics: Aged; Anticoagulants; Aspirin; Cardiovascular Diseases; Cerebral Hemorrhage; Drug Therapy, Combinati

2009
How can we reduce disagreement among guidelines for venous thromboembolism prevention?
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:4

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgical; Cast

2010
The effect of clopidogrel and aspirin on blood loss in hip fracture surgery.
    Injury, 2011, Volume: 42, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Drug Therapy

2011
Treatment of GERD and proton pump inhibitor use in the elderly: practical approaches and frequently asked questions.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:3

    Topics: Adenocarcinoma; Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Aspirin; Barrett Esop

2011
Bleeding and first-year mortality following hip fracture surgery and preoperative use of low-dose acetylsalicylic acid: an observational cohort study.
    BMC musculoskeletal disorders, 2011, Nov-07, Volume: 12

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Cohort Studies; Dose-Response Relationship,

2011
Little impact of antiplatelet agents on venous thromboembolism after hip fracture surgery.
    Journal of Korean medical science, 2011, Volume: 26, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Female; Hip Fractures; Humans;

2011
The effects of clopidogrel (Plavix) and other oral anticoagulants on early hip fracture surgery.
    Journal of orthopaedic trauma, 2012, Volume: 26, Issue:10

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Cohort Studies;

2012
Clopidogrel has no effect on mortality from hip fracture.
    Injury, 2013, Volume: 44, Issue:6

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Aspirin; Bl

2013
The association between aspirin and blood loss in hip fracture patients.
    Acta orthopaedica Belgica, 2006, Volume: 72, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Bleeding Time; Blood Loss, Surgical; Blood Transfusion; Case-Contr

2006
Thromboprophylaxis in orthopedic surgery.
    American journal of orthopedics (Belle Mead, N.J.), 2006, Volume: Suppl

    Topics: Anesthesia, Epidural; Anesthesia, Spinal; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement,

2006
Thromboprophylaxis after hip fracture: evaluation of 3 pharmacologic agents.
    American journal of orthopedics (Belle Mead, N.J.), 2007, Volume: 36, Issue:3

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Dextrans; Enoxaparin; Female; Fibrinolytic Agents;

2007
Anti-platelet agents and surgical delay in elderly patients with hip fractures.
    Journal of orthopaedic surgery (Hong Kong), 2007, Volume: 15, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Female; Hip Fractures; Humans; Male; Platelet Aggrega

2007
Anti-platelet agents and surgical delay in elderly patients with hip fractures.
    Journal of orthopaedic surgery (Hong Kong), 2008, Volume: 16, Issue:1

    Topics: Aged; Aspirin; Bleeding Time; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Hip Fractures; Hum

2008
Clinical efficacy of aspirin and dextran for thromboprophylaxis in geriatric hip fracture patients.
    Journal of orthopaedic trauma, 1993, Volume: 7, Issue:1

    Topics: Aged; Aspirin; Dextrans; Female; Hip Fractures; Humans; Male; Prospective Studies; Pulmonary Embolis

1993
Predictors of mortality after acute hip fracture.
    Journal of general internal medicine, 1996, Volume: 11, Issue:12

    Topics: Aged; Aged, 80 and over; Aspirin; Comorbidity; Female; Hip Fractures; Hospital Mortality; Humans; Io

1996
Can low-dose aspirin prevent thromboembolic phenomena in patients undergoing surgery for hip fracture or elective arthroplasty?
    The Journal of family practice, 2000, Volume: 49, Issue:7

    Topics: Anticoagulants; Arthroplasty, Replacement; Aspirin; Cause of Death; Double-Blind Method; Follow-Up S

2000
PEP trial. Pulmonary Embolism Prevention.
    Lancet (London, England), 2000, Jul-15, Volume: 356, Issue:9225

    Topics: Aspirin; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Hip Fractures; Humans; Meta-Analysis as

2000
PEP trial. Pulmonary Embolism Prevention.
    Lancet (London, England), 2000, Jul-15, Volume: 356, Issue:9225

    Topics: Aspirin; Hip Fractures; Humans; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Pulmonary

2000
PEP trial. Pulmonary Embolism Prevention.
    Lancet (London, England), 2000, Jul-15, Volume: 356, Issue:9225

    Topics: Aged; Arthroplasty, Replacement, Hip; Aspirin; Hip Fractures; Humans; Male; Myocardial Infarction; P

2000
Thromboprophylaxis--which treatment for which patient?
    The Journal of bone and joint surgery. British volume, 2000, Volume: 82, Issue:7

    Topics: Arthroplasty, Replacement, Hip; Aspirin; Chemoprevention; Fibrinolytic Agents; Hip Fractures; Humans

2000
Prophylactic low-dose aspirin therapy in patients having hip-fracture surgery or elective arthroplasty.
    The Journal of bone and joint surgery. American volume, 2001, Volume: 83, Issue:8

    Topics: Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Hip Fractu

2001
Aspirin prophylaxis of venous thromboembolic disease following fracture of the upper femur.
    Canadian journal of surgery. Journal canadien de chirurgie, 1979, Volume: 22, Issue:5

    Topics: Aged; Aspirin; Female; Femoral Neck Fractures; Hip Fractures; Hip Prosthesis; Humans; Male; Middle A

1979
Femoral artery laceration complicating an intertrochanteric hip fracture: a multi-disciplinary therapeutic problem.
    Orthopedics, 1985, Volume: 8, Issue:12

    Topics: Aged; Aspirin; Embolization, Therapeutic; Female; Femoral Artery; Hematoma; Hip Fractures; Humans; O

1985