Page last updated: 2024-10-23

aspirin and Hemorrhagic Thrombocythemia

aspirin has been researched along with Hemorrhagic Thrombocythemia in 186 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"The role of aspirin in the antithrombotic strategy of patients with polycythemia vera (PV) and essential thrombocythemia (ET) is highly controversial."10.18Aspirin in polycythemia vera and essential thrombocythemia: current facts and perspectives. ( Landolfi, R; Patrono, C, 1996)
" From 1974 to 1986 we treated 20 symptomatic ET patients with microvascular circulation disturbances including erythromelalgia (N = 18), atypical or typical transient ischemic attacks (N = 6), or acute coronary ischemic syndrome (N = 3) with aspirin and one course of busulfan."9.09Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia. ( Michiels, JJ, 1999)
" Considering the clear risk of complications during pregnancy -- especially the occurrence of spontaneous abortion in the first trimester -- and the risk of intrauterine fetal death, we believe all patients should at least be treated with aspirin unless there is a contraindication."8.81Management of essential thrombocythemia during pregnancy with aspirin, interferon alpha-2a and no treatment. A comparative analysis of the literature. ( Vanstraelen, D; Vantroyen, B, 2002)
" MIAs were frequently preceded or followed by ocular ischemic events of blurred vision, scotomas, transient flashing of the eyes, and sudden transient partial blindness preceded or followed erythromelalgia in the toes or fingers."7.81Aspirin-responsive, migraine-like transient cerebral and ocular ischemic attacks and erythromelalgia in JAK2-positive essential thrombocythemia and polycythemia vera. ( Berneman, Z; De Raeve, H; Gadisseur, A; Lam, KH; Michiels, JJ; Schroyens, W, 2015)
"The effectiveness of low-dose aspirin in the primary prevention of thrombosis in patients with high-risk essential thrombocythaemia (ET) treated with cytoreductive drugs is not well established."7.79Cytoreduction plus low-dose aspirin versus cytoreduction alone as primary prophylaxis of thrombosis in patients with high-risk essential thrombocythaemia: an observational study. ( Alvarez-Larrán, A; Arellano-Rodrigo, E; Besses, C; Cervantes, F; Hernández-Boluda, JC; Pereira, A, 2013)
"The role of aspirin in the antithrombotic strategy of patients with polycythemia vera (PV) and essential thrombocythemia (ET) is highly controversial."6.18Aspirin in polycythemia vera and essential thrombocythemia: current facts and perspectives. ( Landolfi, R; Patrono, C, 1996)
"Essential thrombocythemia is a rare disease of unknown origin characterized by abnormal increase in the platelet count."5.32Pregnancy in essential thrombocythemia during aspirin treatment. ( Cannata, ML; Corrado, F; Ruggeri, Z; Stella, NC, 2003)
" As compared with hydroxyurea plus aspirin, anagrelide plus aspirin was associated with increased rates of arterial thrombosis (P=0."5.11Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. ( Bareford, D; Buck, G; Campbell, PJ; East, CL; Green, AR; Grigg, AP; Harrison, CN; Reilly, JT; Revell, P; van der Walt, JD; Wheatley, K; Wilkins, BS; Woodcock, BE, 2005)
" From 1974 to 1986 we treated 20 symptomatic ET patients with microvascular circulation disturbances including erythromelalgia (N = 18), atypical or typical transient ischemic attacks (N = 6), or acute coronary ischemic syndrome (N = 3) with aspirin and one course of busulfan."5.09Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia. ( Michiels, JJ, 1999)
" Results of the first phase III trial (PT1) that compared anagrelide/aspirin with hydroxyurea/aspirin have sparked an intense discussion, given that the combination of anagrelide and aspirin causes more bleeding complications in the gastrointestinal tract."4.83Anagrelide: what was new in 2004 and 2005? ( Petrides, PE, 2006)
" Considering the clear risk of complications during pregnancy -- especially the occurrence of spontaneous abortion in the first trimester -- and the risk of intrauterine fetal death, we believe all patients should at least be treated with aspirin unless there is a contraindication."4.81Management of essential thrombocythemia during pregnancy with aspirin, interferon alpha-2a and no treatment. A comparative analysis of the literature. ( Vanstraelen, D; Vantroyen, B, 2002)
" Randomized studies have shown that the risk of thrombosis was significantly reduced in ET with the use of hydroxyurea (HU) and in PV with the use of chlorambucil or 32P."4.80Treatment of polycythaemia vera and essential thrombocythaemia. ( Silverstein, MN; Tefferi, A, 1998)
"Aspirin has a well established role in the prevention of arterial thrombosis."4.79Aspirin in essential thrombocythemia: status quo and quo vadis. ( Bangerter, M; Griesshammer, M; Michiels, JJ; van Vliet, HH, 1997)
" MIAs were frequently preceded or followed by ocular ischemic events of blurred vision, scotomas, transient flashing of the eyes, and sudden transient partial blindness preceded or followed erythromelalgia in the toes or fingers."3.81Aspirin-responsive, migraine-like transient cerebral and ocular ischemic attacks and erythromelalgia in JAK2-positive essential thrombocythemia and polycythemia vera. ( Berneman, Z; De Raeve, H; Gadisseur, A; Lam, KH; Michiels, JJ; Schroyens, W, 2015)
"The effectiveness of low-dose aspirin in the primary prevention of thrombosis in patients with high-risk essential thrombocythaemia (ET) treated with cytoreductive drugs is not well established."3.79Cytoreduction plus low-dose aspirin versus cytoreduction alone as primary prophylaxis of thrombosis in patients with high-risk essential thrombocythaemia: an observational study. ( Alvarez-Larrán, A; Arellano-Rodrigo, E; Besses, C; Cervantes, F; Hernández-Boluda, JC; Pereira, A, 2013)
"All the patients were treated with low dose aspirin during the pregnancy."3.77[Pregnancy and essential thrombocytemia]. ( Cambier, N; Depret, S; Deruelle, P; Ducloy, AS; Giraudet, G; Houfflin-Debarge, V; Vaast, P; Wibaut, B, 2011)
" Erythromelalgia is causally related to thrombocythaemia; prompt relief of painful symptoms after treatment with aspirin is typical."3.69[Cutaneous manifestations of essential thrombocythemia. Erythromelalgia, ischemic acrocyanosis, livedo racemosa]. ( Bauerschmitz, J; Knop, J, 1995)
" The antiplatelet response to low-dose aspirin can be markedly improved by shortening the dosing interval to 12 hours, with no improvement with further reductions (EudraCT 2016-002885-30)."2.94A randomized double-blind trial of 3 aspirin regimens to optimize antiplatelet therapy in essential thrombocythemia. ( Beggiato, E; Bertozzi, I; Betti, S; Bucelli, C; Carli, G; Carpenedo, M; Cattaneo, D; Cavalca, V; De Stefano, V; Di Ianni, M; Dragani, A; Elli, EM; Iurlo, A; Lanzarone, G; Palandri, F; Paoli, C; Patrono, C; Petrucci, G; Porro, B; Ranalli, P; Randi, ML; Ricco, A; Rocca, B; Rodeghiero, F; Rossi, E; Ruggeri, M; Soldati, D; Specchia, G; Timillero, A; Tosetto, A; Vannucchi, AM; Vianelli, N, 2020)
" A twice daily (bid) dosing is necessary to fully inhibit TXA2."2.79In vivo prostacyclin biosynthesis and effects of different aspirin regimens in patients with essential thrombocythaemia. ( Barbieri, SS; Cavalca, V; Dragani, A; Pagliaccia, F; Patrono, C; Porro, B; Rocca, B; Squellerio, I; Tremoli, E; Veglia, F, 2014)
" In the present study, we investigated the determinants of aspirin-insensitive platelet TXA(2) biosynthesis and whether it could be further suppressed by changing the aspirin dose, formulation, or dosing interval."2.77Aspirin-insensitive thromboxane biosynthesis in essential thrombocythemia is explained by accelerated renewal of the drug target. ( Dragani, A; Habib, A; Pagliaccia, F; Pascale, S; Patrono, C; Petrucci, G; Pocaterra, D; Ragazzoni, E; Rocca, B; Rolandi, G; Zaccardi, F, 2012)
"Aspirin was fully efficient in only 30% of cases."2.76Neurological disorders in essential thrombocythemia. ( Billot, S; Carpentier, AF; Cassinat, B; Fenaux, P; Jardin, C; Kiladjian, JJ; Kouroupi, EG; Laperche, T; Le Guilloux, J, 2011)
"Essential thrombocythemia is associated with an increased risk of thromboembolic complications."2.74The influence of low-dose aspirin and hydroxyurea on platelet-leukocyte interactions in patients with essential thrombocythemia. ( Chojnowski, K; Robak, T; Smolewski, P; Treliński, J; Tybura, M, 2009)
"Pregnancy is not contraindicated in MPNs, and we recommend aspirin throughout pregnancy with consideration for prophylactic postpartum anticoagulation."2.72Management Issues and Controversies in Low-Risk Patients with Essential Thrombocythemia and Polycythemia Vera. ( Hobbs, G; How, J, 2021)
"The priapism was managed with repeated aspiration and instillation of phenylephrine."2.66Essential Thrombocythemia Presenting with Recurrent Priapism: A Case Report and Review of Literature. ( Jain, M; Kumar, N; Tripathi, AK; Verma, SP, 2020)
"Controlled studies are needed to confirm the clinical outcome value of twice-daily vs once-daily aspirin dosing and the therapeutic role of pegylated interferons and direct oral anticoagulants."2.66Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2020)
" Each case showed a marked platelet decrease, from values within normal limits at the time of delivery, with no severe adverse events."2.58Efficacy and safety of interferon alpha for essential thrombocythemia during pregnancy: two cases and a literature review. ( Hasegawa, M; Sakai, K; Ueda, A; Ueda, Y, 2018)
"Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms, respectively characterized by erythrocytosis and thrombocytosis."2.52Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2015)
"Essential thrombocythemia is a chronic myeloproliferative neoplasm characterized by sustained thrombocytosis, bone marrow megakaryocytic hyperplasia and an increased risk of thrombosis and hemorrhage."2.49[Treatment of essential thrombocythemia]. ( Alvarez-Larrán, A; Besses, C; Cervantes, F, 2013)
"Treatment with busulfan or interferon-α is usually effective in hydroxyurea failures."2.48Polycythemia vera and essential thrombocythemia: 2012 update on diagnosis, risk stratification, and management. ( Tefferi, A, 2012)
"Because of the rarity of primary thrombocythemia thus far only two prospectively randomized studies have been carried out to compare cyto- and thromboreductive therapies."2.43[Primary thrombocythemia: diagnosis and therapy]. ( Petrides, PE, 2006)
"Essential thrombocythemia is a distinct clinical entity within the spectrum of myeloproliferative disorders."2.42Essential thrombocythemia. ( Green, AR; Harrison, CN, 2003)
"The striking similarity to migraine, together with the absence of vascular risk factors and the striking efficacy of aspirin treatment supports the hypothesis that the ischemic neurologic and visual symptoms in ET are caused by shear rate-induced intravascular activation and aggregation of platelets with subsequent transient sludging or occlusion of the cerebral arterial microvasculature."2.40Neurologic and visual symptoms in essential thrombocythemia: efficacy of low-dose aspirin. ( Koudstaal, A; Koudstaal, PJ, 1997)
"Essential thrombocythemia is a chronic myeloproliferative disease characterized by persistent thrombocytosis and an increased risk of thromboembolic complications."2.40[A management program for primary thrombocytopenia]. ( Bruserud, O; Knutsen, H, 1999)
"Essential thrombocythemia is a myeloproliferative disorder characterized by a persistent increase in the platelet count."2.40Essential thrombocythemia during pregnancy. ( Eliyahu, S; Shalev, E, 1997)
"Placental infarction due to thrombosis seems to be the most consistent pathological event as far as the fetus is concerned."2.39Essential thrombocythemia and pregnancy. ( Griesshammer, M; Heimpel, H; Pearson, TC, 1996)
"One pregnancy was complicated by superficial thrombophlebitis and a postpartum haemorrhage."2.38Primary thrombocythaemia in pregnancy. ( Anderson, CC; Beard, J; Hillmen, P; Lewis, SM; Pearson, TC, 1991)
"A computational approach involving mathematical modeling and in silico experiments was used to characterize the determinants of extent and duration of platelet cyclooxygenase (COX)-1 inhibition by aspirin and design precision dosing in patients with accelerated platelet turnover or reduced drug bioavailability."1.72Physiologically based modelling of the antiplatelet effect of aspirin: A tool to characterize drug responsiveness and inform precision dosing. ( Giaretta, A; Petrucci, G; Rocca, B; Toffolo, GM, 2022)
"Nine pregnancies ended in miscarriages (9/34; 26."1.62Interferon alpha for essential thrombocythemia during 34 high-risk pregnancies: outcome and safety. ( Becker, T; Griesshammer, M; Heidel, FH; Hochhaus, A; Kolatzki, V; Sadjadian, P; Schrickel, L; Wille, K, 2021)
"Risk of thrombosis is higher in JAK2-mutated ET."1.51Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2019)
"Polycythemia Vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly, thrombosis, bleeding, microcirculatory symptoms, pruritus, and risk of leukemic or fibrotic transformation."1.46Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk-stratification, and management. ( Barbui, T; Tefferi, A, 2017)
"Essential thrombocythemia is characterized by persistent elevation and functional disturbances of platelets."1.37Direct evidence for normalization of platelet function resulting from platelet count reduction in essential thrombocythemia. ( Chondropoulos, S; Dervenoulas, J; Kapsimali, V; Kopterides, P; Mantzios, G; Nikolopoulos, GK; Tsantes, AE; Tsirigotis, P; Zoi, K; Zomas, A, 2011)
"Essential thrombocythemia is a rare myleoproliferative disorder in pediatrics."1.35Essential thrombocythemia in a child with elevated thrombopoietin concentrations and skeletal anomalies. ( Niazi, M; Robins, EB, 2008)
"We report a case of ET and chronic renal failure treated with anagrelide and low-dose aspirin in a patient who did not receive transfusion and surgical intervention due to religious reasons, and had a fatal outcome."1.35Management of refractory essential thrombocythemia with anagrelide in a patient undergoing hemodialysis. ( Demulder, AC; Malarme, M; Mesquita, Mdo C; Noubouossie, D; Sol, EB, 2009)
"21/29, 72."1.35Outcome of 122 pregnancies in essential thrombocythemia patients: A report from the Italian registry. ( Candoni, A; Cascavilla, N; Cedrone, M; Ciancia, R; Comitini, G; Gugliotta, L; Latagliata, R; Martinelli, V; Martino, B; Melillo, L; Palmieri, F; Radaelli, F; Scalzulli, PR; Specchia, G; Tieghi, A; Usala, E; Valente, D; Valvano, MR, 2009)
"Furthermore, the occurrence of a miscarriage in ET might be a marker for a similar event during subsequent pregnancies."1.35Predictors of pregnancy outcome in essential thrombocythemia: a single institution study of 63 pregnancies. ( Gangat, N; Schwager, S; Tefferi, A; Wolanskyj, AP, 2009)
"Essential thrombocythemia is a rare disease of unknown origin characterized by abnormal increase in the platelet count."1.32Pregnancy in essential thrombocythemia during aspirin treatment. ( Cannata, ML; Corrado, F; Ruggeri, Z; Stella, NC, 2003)
"Management of ET in pregnancy is still very much individualized."1.31Four pregnancies in two patients with essential thrombocythaemia--a case report. ( Devendra, K; Koh, LP; Tien, SL, 2002)
"Hydroxyurea was given to patients with ET with a positive history for major vascular complications or with an extreme thrombocytosis."1.30Acute coronary disease in essential thrombocythemia and polycythemia vera. ( Girolami, A; Randi, ML; Rinaldi, V; Rossi, C; Zerbinati, P, 1998)
"Treatment with aspirin inhibited spontaneous platelet aggregation but had little effect on the activated platelet profile."1.29Platelet activation and thrombosis: studies in a patient with essential thrombocythemia. ( Bihour, C; Nurden, AT; Nurden, P; Raymond, JM; Smith, M, 1996)
"A 59-year-old man had central retinal vein occlusion in the left eye as the initial sign of essential thrombocythemia."1.29Essential thrombocythemia and central retinal vein occlusion with neovascular glaucoma. ( Townsend-Pico, W; Yoshizumi, MO, 1996)
"Aspirin was prescribed for the next 2 years at varying doses and frequency."1.28Essential thrombocythemia in a child: management with anagrelide. ( Chintagumpala, MM; Fernbach, DJ; Mahoney, DH; Ogden, AK; Steuber, CP, 1991)
"Primary thrombocythemia is a myeloproliferative disease characterized by a sustained and marked increase in platelet count."1.27[Primary thrombocythemia in childhood]. ( de Vaan, G; Flapper, B; Van Oostrom, C, 1983)

Research

Studies (186)

TimeframeStudies, this research(%)All Research%
pre-199013 (6.99)18.7374
1990's39 (20.97)18.2507
2000's54 (29.03)29.6817
2010's51 (27.42)24.3611
2020's29 (15.59)2.80

Authors

AuthorsStudies
How, J1
Hobbs, G1
Tosetto, A3
Rocca, B8
Petrucci, G7
Betti, S4
Soldati, D3
Rossi, E3
Timillero, A3
Cavalca, V4
Porro, B3
Iurlo, A3
Cattaneo, D3
Bucelli, C2
Dragani, A7
Di Ianni, M2
Ranalli, P4
Palandri, F3
Vianelli, N3
Beggiato, E3
Lanzarone, G3
Ruggeri, M4
Carli, G3
Elli, EM2
Priolo, S1
Randi, ML12
Bertozzi, I5
Loscocco, GG2
Ricco, A3
Specchia, G4
Vannucchi, AM7
Rodeghiero, F4
De Stefano, V4
Patrono, C8
Goulart, H1
Mascarenhas, J1
Tremblay, D1
Edahiro, Y1
Kishi, Y1
Aota, Y1
Horie, Y1
Sutoh, A1
Moriyama, M1
Okabe, M1
Iguchi, T1
Yokouchi, Y1
Gotoh, A1
Maetani, I1
Nicol, C1
Ajzenberg, N1
Lacut, K1
Couturaud, F1
Lippert, E2
Pan-Petesch, B1
Ianotto, JC4
Pedersen, OB1
Grove, EL1
Pasalic, L1
Ommen, HB1
Kristensen, SD1
Hvas, AM1
Stuckey, R1
Santoro, M1
Czyż, A1
Perez Encinas, MM1
Gómez-Casares, MT1
Noya Pereira, MS1
de Nałęcz, AK1
Gołos, A1
Lewandowski, K1
Szukalski, Ł1
González-Martín, JM1
Wróbel, T1
Sobas, MA1
Giaretta, A1
Toffolo, GM1
Cattaneo, M2
Khodier, M1
Gadó, K1
Tefferi, A20
Pardanani, A3
Arimura, A1
Fujii, K1
Hayashida, M1
Higashi, Y1
Hashiguchi, T1
Kanekura, T1
Fleischman, RA1
Rumi, E3
Cazzola, M2
Carpenedo, M2
Paoli, C2
Bolaman, AZ1
Yavaşoǧlu, İ2
Kellner, A1
Dombi, P2
Illes, A2
Demeter, J2
Homor, L2
Ercsei, I1
Simon, Z2
Karadi, E2
Herczeg, J1
Gy Korom, V1
Gasztonyi, Z1
Szerafin, L1
Udvardy, M2
Egyed, M2
Rebière, V1
Tudesq, JJ1
Chauveau, A2
Eveillard, JR1
Darmon, M1
Braunstein, EM1
Chaturvedi, S1
Verma, SP1
Kumar, N1
Jain, M1
Tripathi, AK1
Barbui, T15
Schrickel, L1
Heidel, FH1
Sadjadian, P1
Becker, T1
Kolatzki, V1
Hochhaus, A1
Griesshammer, M8
Wille, K1
Xie, J1
Geng, L1
Yuan, B1
Guo, Y1
Zhang, Z1
Okada, Y2
Kimura, F1
Scavone, M1
Podda, GM1
Bossi, E1
Paroni, R1
Szuber, N1
Hanson, CA1
Gangat, N3
Antonioli, E1
Romano, I1
Vergoni, F1
Rotunno, G1
Mannelli, F1
Guglielmelli, P1
Choi, HS1
Hong, J1
Hwang, SM1
Lee, JH1
Ma, Y1
Kim, SA1
Lee, JY1
Lee, JO1
Bang, SM1
Kempen, PM1
Sakai, K1
Ueda, A1
Hasegawa, M1
Ueda, Y1
Ventejou, S1
Delaplace, M1
Dehayes, P1
Bailly, E1
Machet, L1
Elli, E2
Finazzi, G7
Lissandrini, L1
Rambaldi, A3
Turnu, L1
Godfrey, AL1
Campbell, PJ2
MacLean, C1
Buck, G2
Cook, J1
Temple, J1
Wilkins, BS2
Wheatley, K2
Nangalia, J1
Grinfeld, J1
McMullin, MF1
Forsyth, C1
Kiladjian, JJ3
Green, AR5
Harrison, CN4
Putti, MC2
Bain, BJ1
Garnett, C1
Deplano, S1
Naresh, K1
Kanfer, E1
Alvarez-Larrán, A3
Cervantes, F2
Besses, C3
Pereira, A1
Arellano-Rodrigo, E1
Hernández-Boluda, JC1
Squizzato, A2
Romualdi, E2
Passamonti, F4
Middeldorp, S2
Haznedaroglu, IC1
Panova-Noeva, M1
Marchetti, M2
Russo, L1
Tartari, CJ1
Leuzzi, A1
ten Cate, H1
Falanga, A2
Ling, C1
Zhu, GH1
Jin, L1
Squellerio, I1
Veglia, F1
Pagliaccia, F2
Barbieri, SS1
Tremoli, E1
Michiels, JJ13
Berneman, Z3
Gadisseur, A1
Lam, KH1
De Raeve, H1
Schroyens, W3
Yoshimoto, G1
Miyamoto, T1
Lancellotti, S1
Basso, M1
Tartaglione, R1
De Cristofaro, R1
Keohane, C1
McLornan, DP1
Sanchez, K1
Connor, C1
Radia, D1
Verger, E1
Cassinat, B2
Dosquet, C1
Giraudier, S1
Schlageter, MH1
Yassin, MA1
Al-Dewik, N1
Carillo, S1
Legouffe, E1
Ugo, V1
Chomienne, C1
Buxhofer-Ausch, V1
Gisslinger, H2
Carobbio, A1
Thiele, J1
Falcone, C1
Villani, M1
Colaizzo, D1
Tiscia, GL1
Chinni, E1
Bodenizza, C1
Cascavilla, N2
Grandone, E1
Sakamoto, Y1
Nito, C1
Abe, A1
Nogami, A1
Sato, T1
Sawada, K1
Hokama, H1
Yamada, M1
Hijikata, N1
Kumagai, T1
Ishiwata, A1
Nagayama, H1
Kimura, K1
Shimazu, Y1
Fujimura, K1
Inoue, S1
Okiyama, N1
Okune, M1
Shiraki, N1
Kessoku, R1
Fujimoto, M1
Piccin, A1
Steurer, M1
Feistritzer, C1
Murphy, C1
Eakins, E1
Van Schilfgaarde, M1
Corvetta, D1
Di Pierro, AM1
Pusceddu, I1
Marcheselli, L1
Gambato, R1
Langes, M1
Veneri, D1
Perbellini, O1
Pacquola, E1
Gottardi, M1
Gherlinzoni, F1
Mega, A1
Tauber, M1
Mazzoleni, G1
Piva, E1
Plebani, M1
Krampera, M1
Gastl, G1
Struve, S1
Birgegård, G1
Bildirici, U1
Celikyurt, U1
Ural, E1
Wolanskyj, AP1
Schwager, S1
Estilita, J1
Alonso, FM1
Brasil, JS1
Baptista, MS1
Melillo, L1
Tieghi, A1
Candoni, A1
Radaelli, F1
Ciancia, R1
Martino, B1
Scalzulli, PR1
Latagliata, R1
Palmieri, F1
Usala, E1
Valente, D1
Valvano, MR1
Cedrone, M1
Comitini, G1
Martinelli, V1
Gugliotta, L1
Kurosawa, H1
Okuya, M1
Matsushita, T1
Kubota, T1
Endoh, K1
Kuwashima, S1
Hagisawa, S1
Sato, Y1
Fukushima, K1
Sugita, K1
Park, MJ1
Hayashi, Y1
Arisaka, O1
Treliński, J1
Tybura, M1
Smolewski, P1
Robak, T1
Chojnowski, K1
Pascale, S2
Recchiuti, A1
Mattoscio, D1
Lattanzio, S1
Mucci, L1
Ferrante, E1
Habib, A2
Ranelletti, FO1
Ciabattoni, G1
Davì, G1
Morra, E1
Beer, PA1
Mesquita, Mdo C1
Sol, EB1
Malarme, M1
Noubouossie, D1
Demulder, AC1
Robier, C1
Neubauer, M1
Sternad, H1
Quehenberger, F1
Rainer, F1
Neumeister, P1
Harrison, C1
Ayvaz, OC1
Kadikoylu, G1
Bozkurt, G1
Bolaman, Z1
Giraudet, G1
Wibaut, B1
Ducloy, AS1
Deruelle, P1
Depret, S1
Cambier, N1
Vaast, P1
Houfflin-Debarge, V1
Tsantes, AE1
Nikolopoulos, GK1
Tsirigotis, P1
Zoi, K1
Zomas, A1
Kapsimali, V1
Kopterides, P1
Chondropoulos, S1
Dervenoulas, J1
Mantzios, G1
Billot, S1
Kouroupi, EG1
Le Guilloux, J1
Jardin, C1
Laperche, T1
Fenaux, P1
Carpentier, AF1
Dillinger, JG1
Sideris, G1
Henry, P1
Bal dit Sollier, C1
Ronez, E1
Drouet, L1
Belotti, A1
Speranza, T1
Lanzi, E1
Pioltelli, P1
Pogliani, E1
Zaccardi, F1
Pocaterra, D1
Ragazzoni, E1
Rolandi, G1
Finazzi, MC1
Frewin, R1
Dowson, A1
Dua, V1
Yadav, SP1
Kumar, V1
Saxena, R1
Sachdeva, A1
Dan, K1
Troost, MM1
van Genderen, PJ4
Ruggeri, Z1
Cannata, ML1
Stella, NC1
Corrado, F1
Langer, C1
Schafer, AI1
Dutrillaux, F1
Maynadié, M1
Carli, PM1
Elliott, MA2
Niittyvuopio, R1
Juvonen, E1
Kaaja, R1
Oksanen, K1
Hallman, H1
Timonen, T1
Ruutu, T1
East, CL1
Bareford, D1
van der Walt, JD1
Reilly, JT2
Grigg, AP1
Revell, P1
Woodcock, BE1
Costello, R1
O'Callaghan, T1
Sébahoun, G1
Landolfi, R3
Di Gennaro, L2
Novarese, L1
Petrides, PE2
Yamaguchi, K1
Hisano, M1
Sakata, M1
Minatogawa, Y1
Suzuki, T1
Ozawa, N1
Kitagawa, M1
Murashima, A1
Budde, U2
van Vliet, HH6
Iwashita, T1
Fujitani, M1
Yamamoto, Y1
Katsurada, T1
Yoshida, Y1
Koudstaal, PJ3
Lindemans, J2
Neumann, HA1
Robins, EB1
Niazi, M1
Usukine, K1
Shinhori, H1
Idetsuki, T1
Taoka, K1
Nakasone, H1
Kida, M1
Iki, S1
Urabe, M1
Oseto, K1
Igarashi, A1
McLornan, D1
McMullin, M1
Cacciola, RR1
Di Francesco, E1
Pezzella, F1
Tibullo, D1
Giustolisi, R1
Cacciola, E1
Bellucci, S1
Dinas, K1
Hatzipantelis, E1
Karasmanis, K1
Zepiridis, L1
Mavromatidis, G1
Bontis, J1
Flapper, B1
Van Oostrom, C1
de Vaan, G1
Fröhli, P1
Graf, C1
Rhyner, K1
Meschengieser, SS1
Woods, AI1
Schattner, MA1
Lazzari, MA1
Oswald, M1
Beuers, U1
Pape, GR1
Paumgartner, G1
Bauerschmitz, J1
Knop, J1
Fuse, I1
Yamamoto, R1
Hirahatake, K1
Yamaguchi, M1
Sato, C1
van Strik, R2
Mulder, AH1
Oliveira, AS1
Miranda, MP1
Duarte, PC1
Sarmento, JN1
Pardini, S1
Dore, F1
Murineddu, M1
Bontigli, S1
Longinotti, M1
Grigliotti, B1
Spano, B1
Nurden, P1
Bihour, C1
Smith, M1
Raymond, JM1
Nurden, AT1
Yoshizumi, MO1
Townsend-Pico, W1
Delage, R1
Demers, C1
Cantin, G1
Roy, J1
Heimpel, H1
Pearson, TC3
Guzzini, F1
Ceppi, M1
Gasparini, P1
Sali, L1
Vecchi, C1
Eliyahu, S1
Shalev, E1
Koudstaal, A1
Bangerter, M4
Leenknegt, H1
Cortelazzo, S2
Orlando, E1
Buchanan, MR1
Willoughby, S1
Rossi, C4
Zerbinati, P1
Rinaldi, V1
Girolami, A4
Luzzatto, G1
Fabris, F4
Knutsen, H1
Bruserud, O1
Beneke, H2
Nussbaumer, B1
Grünewald, M3
Bergmann, L1
Silverstein, MN1
Menapace, L1
Güthner, C1
Hildebrand, A1
Kudo, K1
Horibe, K1
Iwase, K1
Kondo, M1
Kojima, S1
Blaser, T1
Krueger, S1
Kross, R1
Lutze, G1
Franke, A1
Wieker, K1
Goertler, M1
Briere, J1
Guilmin, F1
Wright, CA1
Vantroyen, B1
Vanstraelen, D1
Koh, LP1
Devendra, K1
Tien, SL1
Vera, JC1
Jeri, A1
Horna, E1
Rojas, M1
Chow, EY1
Haley, LP1
Vickars, LM1
Solal-Céligny, P1
Fernandez, H1
Tertian, G1
Campbell, KM1
Schubert, DS1
Scheffer, MG1
Simoons, ML1
Roelandt, JR1
Pineo, GF1
Blahey, WB1
Beard, J1
Hillmen, P1
Anderson, CC1
Lewis, SM1
Chintagumpala, MM1
Steuber, CP1
Mahoney, DH1
Ogden, AK1
Fernbach, DJ1
Bottaro, T1
Cordì, GC1
Gaggero, E1
Motta, A1
Venzano, C1
Buelli, M1
Viero, P1
De Gaetano, G1
Louwerenburg, JW1
Suttorp, MJ1
Herie Kingma, J1
Falconer, J1
Pineo, G1
Blahey, W1
Bowen, T1
Docksteader, B1
Jadusingh, I1
Snethlage, W1
Ten Cate, JW1
Preston, FE1
Emmanuel, IG1
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Malia, RG1
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Rossi, EC1
Geraud, J1
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Guiraud, B1
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Gayrard, M1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised Trial to Compare Aspirin vs Hydroxyurea/Aspirin in 'Intermediate Risk' Primary Thrombocythaemia and Aspirin Only With Observation in 'Low Risk'Primary Thrombocythaemia[NCT00175838]1,398 participants (Actual)Interventional1997-07-31Completed
French Aspirin Study in Essential Thrombocythemia: an Open and Randomized Study[NCT02611973]Phase 32,250 participants (Anticipated)Interventional2016-03-10Recruiting
Mechanism of Action of Interferon in the Treatment of Myeloproliferative Neoplasms[NCT05850273]50 participants (Anticipated)Observational2023-03-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

63 reviews available for aspirin and Hemorrhagic Thrombocythemia

ArticleYear
Management Issues and Controversies in Low-Risk Patients with Essential Thrombocythemia and Polycythemia Vera.
    Current hematologic malignancy reports, 2021, Volume: 16, Issue:5

    Topics: Animals; Aspirin; Disease Management; Female; Humans; Phlebotomy; Platelet Aggregation Inhibitors; P

2021
Low-risk polycythemia vera and essential thrombocythemia: management considerations and future directions.
    Annals of hematology, 2022, Volume: 101, Issue:5

    Topics: Aspirin; Humans; Myeloproliferative Disorders; Polycythemia Vera; Primary Myelofibrosis; Quality of

2022
Treatment options and pregnancy management for patients with PV and ET.
    International journal of hematology, 2022, Volume: 115, Issue:5

    Topics: Aspirin; Female; Humans; Hydroxyurea; Janus Kinase 2; Janus Kinase Inhibitors; Myeloproliferative Di

2022
Aspirin in essential thrombocythemia. For whom? What formulation? What regimen?
    Haematologica, 2023, 06-01, Volume: 108, Issue:6

    Topics: Aspirin; Blood Platelets; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Prostaglandin-Endoper

2023
BCR::ABL1 negative myeloproliferative neoplasms: A review focused on essential thrombocythemia and polycythemia vera.
    Physiology international, 2023, Sep-05, Volume: 110, Issue:3

    Topics: Aspirin; Humans; Hydroxyurea; Mutation; Polycythemia Vera; Thrombocythemia, Essential

2023
Essential Thrombocythemia.
    The New England journal of medicine, 2019, 11-28, Volume: 381, Issue:22

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Female; Humans; Megakaryocytes; Middle Aged; Mutatio

2019
Essential Thrombocythemia Presenting with Recurrent Priapism: A Case Report and Review of Literature.
    The American journal of case reports, 2020, Jul-28, Volume: 21

    Topics: Adult; Antineoplastic Agents; Aspirin; Cytoreduction Surgical Procedures; Humans; Hydroxyurea; Male;

2020
Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2020, Volume: 95, Issue:12

    Topics: Age Factors; Aspirin; Busulfan; Calreticulin; Disease-Free Survival; Humans; Interferon-alpha; Janus

2020
Extreme thrombocytosis in low-risk essential thrombocythemia: Retrospective review of vascular events and treatment strategies.
    American journal of hematology, 2021, 06-01, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Aspirin; Calreticulin; Disease-Free Survival; Erythrocyte Transfusion; Female; Fo

2021
Efficacy and safety of interferon alpha for essential thrombocythemia during pregnancy: two cases and a literature review.
    International journal of hematology, 2018, Volume: 108, Issue:2

    Topics: Adult; Aspirin; Drug Therapy, Combination; Female; Humans; Interferon-alpha; Platelet Count; Pregnan

2018
Contemporary management of essential thrombocythemia in children.
    Expert review of hematology, 2019, Volume: 12, Issue:5

    Topics: Anticoagulants; Aspirin; Calreticulin; Child; Disease Management; Humans; Hydroxyurea; Interferon-al

2019
[Treatment of essential thrombocythemia].
    Medicina clinica, 2013, Sep-21, Volume: 141, Issue:6

    Topics: Adult; Age Factors; Aged; Anticoagulants; Aspirin; Cell Transformation, Neoplastic; Disease Progress

2013
Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia.
    The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4

    Topics: Anticoagulants; Aspirin; Humans; Platelet Aggregation Inhibitors; Polycythemia Vera; Randomized Cont

2013
Antiplatelet therapy in the management of myeloproliferative neoplasms.
    Current hematologic malignancy reports, 2014, Volume: 9, Issue:4

    Topics: Aspirin; Disease Management; Female; Humans; Male; Myeloproliferative Disorders; Platelet Aggregatio

2014
[Treatment strategy for myeloproliferative neoplasms].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Adrenal Cortex Hormones; Aspirin; Calreticulin; Carbamates; Clinical Trials as Topic; Drug Therapy,

2014
Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2015, Volume: 90, Issue:2

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Disease Management; Humans; Hydroxyurea; Janus Kinas

2015
Essential Thrombocythemia and Polycythemia Vera: Focus on Clinical Practice.
    Mayo Clinic proceedings, 2015, Volume: 90, Issue:9

    Topics: Aspirin; Diagnosis, Differential; Disease Management; Disease Progression; Humans; Janus Kinase 2; P

2015
Clinical and histological characteristics of livedo racemosa in essential thrombocythemia: A report of two cases and review of the published works.
    The Journal of dermatology, 2017, Volume: 44, Issue:1

    Topics: Aged; Aspirin; Calreticulin; Humans; Hydroxyurea; Janus Kinase 2; Livedo Reticularis; Male; Middle A

2017
Pharmacotherapy of essential thrombocythemia.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:10

    Topics: Age Factors; Antineoplastic Agents; Aspirin; Disease Progression; Humans; Hydroxyurea; Interferon-al

2008
Evidence and expertise in the management of polycythemia vera and essential thrombocythemia.
    Leukemia, 2008, Volume: 22, Issue:8

    Topics: Aspirin; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Mutation; Phlebotomy; Polycythemia V

2008
Management of Philadelphia negative chronic myeloproliferative disorders in pregnancy.
    Blood reviews, 2008, Volume: 22, Issue:5

    Topics: Aspirin; Female; Heparin, Low-Molecular-Weight; Humans; Platelet Aggregation Inhibitors; Polycythemi

2008
Long-term management of thrombocytosis in essential thrombocythaemia.
    Annals of hematology, 2009, Volume: 88, Issue:1

    Topics: Algorithms; Antineoplastic Agents; Aspirin; Female; Fibrinolytic Agents; Humans; Hydroxyurea; Interf

2009
Insights into the pathogenesis and management of thrombosis in polycythemia vera and essential thrombocythemia.
    Internal and emergency medicine, 2010, Volume: 5, Issue:3

    Topics: Aspirin; Humans; Janus Kinase 2; Leukocytosis; Mutation; Platelet Aggregation Inhibitors; Polycythem

2010
Pathogenesis and management of essential thrombocythemia.
    Hematology. American Society of Hematology. Education Program, 2009

    Topics: Acute Disease; Aged; Aspirin; Clone Cells; Disease Management; Disease Progression; Humans; Hydroxyu

2009
Polycythemia vera and essential thrombocythemia: 2012 update on diagnosis, risk stratification, and management.
    American journal of hematology, 2012, Volume: 87, Issue:3

    Topics: Acute Disease; Age Factors; Alkylating Agents; Anticoagulants; Aspirin; Busulfan; Disease Management

2012
Front-line therapy in polycythemia vera and essential thrombocythemia.
    Blood reviews, 2012, Volume: 26, Issue:5

    Topics: Aspirin; Humans; Phlebotomy; Polycythemia Vera; Risk Factors; Thrombocythemia, Essential

2012
Headache in essential thrombocythaemia.
    International journal of clinical practice, 2012, Volume: 66, Issue:10

    Topics: Alkylating Agents; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Headache Disorders;

2012
Pharmacotherapy of essential thrombocythaemia: economic considerations.
    Expert opinion on pharmacotherapy, 2003, Volume: 4, Issue:9

    Topics: Age Factors; Antineoplastic Agents; Aspirin; Clinical Trials, Phase II as Topic; Cost-Benefit Analys

2003
Essential thrombocythemia.
    Hematology/oncology clinics of North America, 2003, Volume: 17, Issue:5

    Topics: Aspirin; Diagnosis, Differential; Female; Humans; Pregnancy; Pregnancy Complications, Hematologic; R

2003
Thrombocytosis.
    The New England journal of medicine, 2004, Mar-18, Volume: 350, Issue:12

    Topics: Aspirin; Clone Cells; Diagnosis, Differential; Humans; Hydroxyurea; Interferon-alpha; Plasmapheresis

2004
Pathogenesis and management of bleeding in essential thrombocythemia and polycythemia vera.
    Current hematology reports, 2004, Volume: 3, Issue:5

    Topics: Aspirin; Bleeding Time; Hemostatics; Humans; Incidence; Platelet Activation; Platelet Aggregation; P

2004
Pregnancy in essential thrombocythaemia: experience with 40 pregnancies.
    European journal of haematology, 2004, Volume: 73, Issue:6

    Topics: Abortion, Spontaneous; Anticoagulants; Aspirin; Eclampsia; Female; Fetal Death; Finland; Humans; Pla

2004
Thrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia.
    British journal of haematology, 2005, Volume: 128, Issue:3

    Topics: Aged; Aspirin; Hemorrhage; Humans; Hydroxyurea; Middle Aged; Polycythemia Vera; Risk Factors; Thromb

2005
[Treatment of essential thrombocythemia].
    La Revue de medecine interne, 2005, Volume: 26, Issue:12

    Topics: Aspirin; Enzyme Inhibitors; Hemorrhage; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha;

2005
Essential thrombocythemia: scientific advances and current practice.
    Current opinion in hematology, 2006, Volume: 13, Issue:2

    Topics: Antineoplastic Agents; Aspirin; Bone Marrow Examination; Humans; Hydroxyurea; In Situ Hybridization,

2006
Aspirin for the control of platelet activation and prevention of thrombosis in essential thrombocythemia and polycythemia vera: current insights and rationale for future studies.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:3

    Topics: Aspirin; Humans; Myeloproliferative Disorders; Platelet Activation; Polycythemia Vera; Thrombocythem

2006
Anagrelide: what was new in 2004 and 2005?
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:4 Pt 2

    Topics: Antineoplastic Agents; Aspirin; Blood Platelets; Clinical Trials, Phase III as Topic; Drug Therapy,

2006
Update on diagnosis and management of essential thrombocythemia.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:4 Pt 2

    Topics: Age Factors; Antineoplastic Agents; Aspirin; Drug Antagonism; Female; Fibrinolytic Agents; Hemorrhag

2006
[Primary thrombocythemia: diagnosis and therapy].
    Medizinische Klinik (Munich, Germany : 1983), 2006, Aug-15, Volume: 101, Issue:8

    Topics: Adult; Aged; Aspirin; Child; Diagnosis, Differential; Drug Therapy, Combination; Enzyme Inhibitors;

2006
The paradox of platelet activation and impaired function: platelet-von Willebrand factor interactions, and the etiology of thrombotic and hemorrhagic manifestations in essential thrombocythemia and polycythemia vera.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:6

    Topics: Aspirin; Bleeding Time; Blood Platelets; Deamino Arginine Vasopressin; Hemorrhage; Humans; Microcirc

2006
How would I manage a case of essential thrombocythaemia presenting with an ischaemic toe.
    Hematological oncology, 2008, Volume: 26, Issue:1

    Topics: Aspirin; Evidence-Based Medicine; Humans; Hydroxyurea; Interferon-alpha; Ischemia; Janus Kinase 2; M

2008
[Vascular complications of essential thrombocythemia].
    Bulletin de l'Academie nationale de medecine, 2007, Volume: 191, Issue:3

    Topics: Age Factors; Aspirin; Case-Control Studies; Controlled Clinical Trials as Topic; Humans; Middle Aged

2007
Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia.
    The Cochrane database of systematic reviews, 2008, Apr-16, Issue:2

    Topics: Anticoagulants; Aspirin; Humans; Platelet Aggregation Inhibitors; Polycythemia Vera; Randomized Cont

2008
Treatment of essential thrombocythemia during pregnancy with interferon-alpha.
    Obstetrics and gynecology, 1996, Volume: 87, Issue:5 Pt 2

    Topics: Adult; Aspirin; Female; Humans; Infant, Newborn; Interferon-alpha; Male; Platelet Aggregation Inhibi

1996
Essential thrombocythemia and pregnancy.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Aspirin; Busulfan; Combined Modality Therapy; Di

1996
Aspirin in polycythemia vera and essential thrombocythemia: current facts and perspectives.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Adult; Aged; Aspirin; Cyclooxygenase Inhibitors; Erythromelalgia; Female; Fibrinolytic Agents; Human

1996
[Primary thrombocythemia in a female carrier of IgA deficiency].
    Recenti progressi in medicina, 1996, Volume: 87, Issue:10

    Topics: Aged; Aspirin; Bacterial Vaccines; Biopsy; Bone Marrow; Chronic Disease; Combined Modality Therapy;

1996
Essential thrombocythemia during pregnancy.
    Obstetrical & gynecological survey, 1997, Volume: 52, Issue:4

    Topics: Adult; Anticoagulants; Aspirin; Dipyridamole; Female; Heparin; Humans; Platelet Aggregation Inhibito

1997
Neurologic and visual symptoms in essential thrombocythemia: efficacy of low-dose aspirin.
    Seminars in thrombosis and hemostasis, 1997, Volume: 23, Issue:4

    Topics: Anticoagulants; Aspirin; Brain Ischemia; Diagnosis, Differential; Erythromelalgia; Headache; Humans;

1997
Aspirin in essential thrombocythemia: status quo and quo vadis.
    Seminars in thrombosis and hemostasis, 1997, Volume: 23, Issue:4

    Topics: Abortion, Habitual; Aspirin; Cerebrovascular Disorders; Cohort Studies; Contraindications; Erythrome

1997
The use of aspirin in polycythaemia vera and primary thrombocythaemia.
    Blood reviews, 1998, Volume: 12, Issue:1

    Topics: Arachidonic Acid; Aspirin; Cyclooxygenase Inhibitors; Humans; Platelet Aggregation Inhibitors; Polyc

1998
[A management program for primary thrombocytopenia].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1999, Sep-30, Volume: 119, Issue:23

    Topics: Adult; Aged; Anticoagulants; Aspirin; Female; Guidelines as Topic; Humans; Hydroxyurea; Interferon T

1999
Treatment of polycythaemia vera and essential thrombocythaemia.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Adult; Aged; Aspirin; Chlorambucil; Disease Progression; Female; Hemorrhage; Humans; Hydroxyurea; In

1998
The pathogenesis and management of essential thrombocythaemia.
    Haematologica, 1999, Volume: 84 Suppl EHA-4

    Topics: Acute Disease; Alkylating Agents; Aspirin; Cardiovascular Diseases; Clone Cells; Gene Expression; He

1999
[Clinical features of essential thrombocythemia in three children].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2000, Volume: 41, Issue:11

    Topics: Aspirin; Child; Dipyridamole; Female; Humans; Male; Thrombocythemia, Essential; Thrombopoietin

2000
Management of patients with essential thrombocythemia: current concepts and perspectives.
    Pathologie-biologie, 2001, Volume: 49, Issue:2

    Topics: Adult; Aged; Aspirin; Case Management; Clinical Trials as Topic; Diagnosis, Differential; Disease Pr

2001
Current treatment practice for essential thrombocythaemia in adults.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:3

    Topics: Adult; Aspirin; Humans; Hydroxyurea; Interferon-alpha; Pipobroman; Prognosis; Quinazolines; Thromboc

2001
A single institutional experience with 43 pregnancies in essential thrombocythemia.
    European journal of haematology, 2001, Volume: 66, Issue:3

    Topics: Abortion, Induced; Abortion, Spontaneous; Abruptio Placentae; Adult; Anticoagulants; Aspirin; Busulf

2001
Management of essential thrombocythemia during pregnancy with aspirin, interferon alpha-2a and no treatment. A comparative analysis of the literature.
    Acta haematologica, 2002, Volume: 107, Issue:3

    Topics: Abortion, Spontaneous; Aspirin; Blood Component Removal; Female; Fetal Death; Gestational Age; Human

2002
[Pregnancy in patients with essential thrombocythemia. Three cases].
    Presse medicale (Paris, France : 1983), 1992, Dec-12, Volume: 21, Issue:43

    Topics: Adult; Aspirin; Female; Heparin, Low-Molecular-Weight; Humans; Platelet Count; Postpartum Period; Pr

1992
Primary thrombocythaemia in pregnancy.
    British journal of haematology, 1991, Volume: 77, Issue:3

    Topics: Abortion, Incomplete; Adult; Aspirin; Female; Humans; Pregnancy; Pregnancy Complications, Hematologi

1991
[Erythromelalgia and thrombotic thrombocythemia].
    Nederlands tijdschrift voor geneeskunde, 1989, May-13, Volume: 133, Issue:19

    Topics: Aspirin; Erythromelalgia; Humans; Thrombocythemia, Essential

1989
Disorders of platelet function.
    The Medical clinics of North America, 1972, Volume: 56, Issue:1

    Topics: Adenosine Diphosphate; Adolescent; Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors;

1972

Trials

15 trials available for aspirin and Hemorrhagic Thrombocythemia

ArticleYear
A randomized double-blind trial of 3 aspirin regimens to optimize antiplatelet therapy in essential thrombocythemia.
    Blood, 2020, 07-09, Volume: 136, Issue:2

    Topics: Adult; Aged; Aspirin; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Double-Blind Method; Epoprostenol

2020
'MPN Genomic Calculator': real-life use in a young population with essential thrombocythaemia.
    British journal of haematology, 2020, Volume: 191, Issue:1

    Topics: Adult; Aged; Aspirin; Female; Genomics; Humans; Male; Middle Aged; Mutation; Thrombocythemia, Essent

2020
The Aspirin Regimens in Essential Thrombocythemia (ARES) phase II randomized trial design: Implementation of the serum thromboxane B
    Blood cancer journal, 2018, 06-01, Volume: 8, Issue:6

    Topics: Aspirin; Biomarkers; Clinical Protocols; Disease Management; Female; Humans; Male; Patient Selection

2018
Hydroxycarbamide Plus Aspirin Versus Aspirin Alone in Patients With Essential Thrombocythemia Age 40 to 59 Years Without High-Risk Features.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018, 12-01, Volume: 36, Issue:34

    Topics: Adult; Aspirin; Australia; Disease Progression; Dose-Response Relationship, Drug; Drug Administratio

2018
In vivo prostacyclin biosynthesis and effects of different aspirin regimens in patients with essential thrombocythaemia.
    Thrombosis and haemostasis, 2014, Jul-03, Volume: 112, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aspirin; Blood Platelets; Clinical Protocols; Drug Dosage Calcul

2014
The effects of JAK inhibitor therapy upon novel markers of thrombosis In myeloproliferative neoplasms.
    Haematologica, 2015, Volume: 100, Issue:9

    Topics: Aspirin; Biomarkers; Female; Hematologic Neoplasms; Humans; Janus Kinase 2; Male; Middle Aged; Nitri

2015
The influence of low-dose aspirin and hydroxyurea on platelet-leukocyte interactions in patients with essential thrombocythemia.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2009, Volume: 20, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Biomarkers; Blood Platelets; Case-Control Studies; Cell Com

2009
The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy.
    Blood, 2010, Feb-04, Volume: 115, Issue:5

    Topics: Adult; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Therapy, Combina

2010
Neurological disorders in essential thrombocythemia.
    Haematologica, 2011, Volume: 96, Issue:12

    Topics: Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Female; H

2011
Aspirin-insensitive thromboxane biosynthesis in essential thrombocythemia is explained by accelerated renewal of the drug target.
    Blood, 2012, Apr-12, Volume: 119, Issue:15

    Topics: Acceleration; Adult; Aged; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over

2012
Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia.
    The New England journal of medicine, 2005, Jul-07, Volume: 353, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Aspirin; Drug Therapy, Combination; Female; F

2005
Effect of anagrelide on platelet coagulant function in patients with essential thrombocythemia.
    Acta haematologica, 2007, Volume: 118, Issue:4

    Topics: Adult; Aged; Antithrombin III; Aspirin; Drug Therapy, Combination; Female; Fibrin Fibrinogen Degrada

2007
Aspirin in polycythemia vera and essential thrombocythemia: current facts and perspectives.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Adult; Aged; Aspirin; Cyclooxygenase Inhibitors; Erythromelalgia; Female; Fibrinolytic Agents; Human

1996
Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 1999, Volume: 5, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Busulfan; Coronary Disease; Dise

1999
Aspirin seems as effective as myelosuppressive agents in the prevention of rethrombosis in essential thrombocythemia.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 1999, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Busulfan; Disease-Free Survival; Female; Hemorr

1999

Other Studies

109 other studies available for aspirin and Hemorrhagic Thrombocythemia

ArticleYear
Association of Platelet Thromboxane Inhibition by Low-Dose Aspirin With Platelet Count and Cytoreductive Therapy in Essential Thrombocythemia.
    Clinical pharmacology and therapeutics, 2022, Volume: 111, Issue:4

    Topics: Aspirin; Cytoreduction Surgical Procedures; Humans; Platelet Aggregation Inhibitors; Platelet Count;

2022
[Idiopathic esophageal submucosal hematoma during antithrombotic therapy for essential thrombocythemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2022, Volume: 63, Issue:4

    Topics: Aged; Aspirin; Chest Pain; Esophageal Diseases; Female; Fibrinolytic Agents; Gastrointestinal Hemorr

2022
Hemorrhages in Polycythemia Vera and Essential Thrombocythemia: Epidemiology, Description, and Risk Factors-Learnings from a Large Cohort.
    Thrombosis and haemostasis, 2022, Volume: 122, Issue:10

    Topics: Aspirin; Hemorrhage; Humans; Hydroxyurea; Male; Polycythemia Vera; Risk Factors; Thrombocythemia, Es

2022
Cytoreductive treatment and association with platelet function and maturity in patients with essential thrombocythaemia.
    British journal of haematology, 2022, Volume: 198, Issue:4

    Topics: Aspirin; Blood Platelets; Humans; Hydroxyurea; Platelet Aggregation; Platelet Function Tests; Thromb

2022
Validation of thrombotic risk factors in 1381 patients with essential thrombocythaemia: A multicentre retrospective real-life study.
    British journal of haematology, 2022, Volume: 199, Issue:1

    Topics: Aspirin; Humans; Prognosis; Retrospective Studies; Risk Factors; Thrombocythemia, Essential; Thrombo

2022
Physiologically based modelling of the antiplatelet effect of aspirin: A tool to characterize drug responsiveness and inform precision dosing.
    PloS one, 2022, Volume: 17, Issue:8

    Topics: Aspirin; Blood Platelets; Humans; Models, Theoretical; Obesity; Platelet Aggregation Inhibitors; Thr

2022
Anagrelide with low-dose aspirin promptly epithelized ulceronecrotic lesion secondary to essential thrombocythemia.
    The Journal of dermatology, 2020, Volume: 47, Issue:5

    Topics: Aspirin; Bone Marrow; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Janus Kin

2020
Essential Thrombocythemia.
    The New England journal of medicine, 2020, 03-19, Volume: 382, Issue:12

    Topics: Aspirin; Humans; Platelet Aggregation Inhibitors; Thrombocythemia, Essential

2020
Essential Thrombocythemia.
    The New England journal of medicine, 2020, 03-19, Volume: 382, Issue:12

    Topics: Aspirin; Humans; Platelet Aggregation Inhibitors; Thrombocythemia, Essential

2020
Essential Thrombocythemia. Reply.
    The New England journal of medicine, 2020, 03-19, Volume: 382, Issue:12

    Topics: Aspirin; Humans; Platelet Aggregation Inhibitors; Thrombocythemia, Essential

2020
Limb gangrene: The first sign of essential thrombocythemia.
    The Indian journal of medical research, 2020, Volume: 151, Issue:4

    Topics: Aged, 80 and over; Amputation, Surgical; Aspirin; Female; Gangrene; Humans; Hydroxyurea; Leg; Platel

2020
Anagrelide influences thrombotic risk, and prolongs progression-free and overall survival in essential thrombocythaemia vs hydroxyurea plus aspirin.
    European journal of haematology, 2020, Volume: 105, Issue:4

    Topics: Aspirin; Drug Therapy, Combination; Health Care Surveys; Humans; Hungary; Hydroxyurea; Quinazolines;

2020
Aspirin in ET: will twice a day keep thrombosis away?
    Blood, 2020, 07-09, Volume: 136, Issue:2

    Topics: Aspirin; Double-Blind Method; Humans; Platelet Aggregation Inhibitors; Thrombocythemia, Essential; T

2020
Interferon alpha for essential thrombocythemia during 34 high-risk pregnancies: outcome and safety.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:5

    Topics: Abortion, Spontaneous; Adult; Aspirin; Female; Heparin, Low-Molecular-Weight; Humans; Interferon-alp

2021
Complex intracranial vascular complications caused by essential thrombocythemia: a critical case report.
    BMC neurology, 2020, Nov-07, Volume: 20, Issue:1

    Topics: Adult; Aspirin; Blood Platelets; Female; Hemorrhage; Humans; Magnetic Resonance Imaging; Mutation; M

2020
Multiple aortic thrombi in essential thrombocythaemia.
    British journal of haematology, 2021, Volume: 193, Issue:5

    Topics: Aged; Aorta, Abdominal; Aspirin; Cefazolin; Echocardiography; Heparin; Humans; Hydroxyurea; Male; St

2021
Acetylsalicylic acid in essential thrombocythemia.
    Wiener klinische Wochenschrift, 2022, Volume: 134, Issue:1-2

    Topics: Aspirin; Humans; Thrombocythemia, Essential

2022
Lenalidomide: A double-edged sword for concomitant multiple myeloma and post-essential thrombocythemia myelofibrosis.
    American journal of hematology, 2021, 06-01, Volume: 96, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Bone Marrow; Calreticulin; Dexamethas

2021
Evaluation of the need for cytoreduction and its potential carcinogenicity in children and young adults with myeloproliferative neoplasms.
    Annals of hematology, 2021, Volume: 100, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents; Aspirin; Child; Female; Fibrinolytic Agents; Follow-Up Stu

2021
Essential Thrombocytosis and Labor Epidural Placement While on Aspirin: Assessing Hemorrhagic Risks: A Case Report.
    A & A case reports, 2017, Sep-15, Volume: 9, Issue:6

    Topics: Adult; Anesthesia, Epidural; Aspirin; Bupivacaine; Female; Fentanyl; Humans; Labor, Obstetric; Lidoc

2017
Painful Erythematous-violaceous Toe: A Quiz.
    Acta dermato-venereologica, 2018, Jul-11, Volume: 98, Issue:7

    Topics: Aged; Aspirin; Blue Toe Syndrome; Erythema; Female; Humans; Pain; Platelet Aggregation Inhibitors; S

2018
Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2019, Volume: 94, Issue:1

    Topics: Adult; Aspirin; Bone Marrow; Busulfan; Disease Management; Disease Progression; Hemorrhage; Humans;

2019
Dysplasia of all granulocyte lineages in myelodysplastic evolution of essential thrombocythemia.
    American journal of hematology, 2013, Volume: 88, Issue:5

    Topics: Aged; Amino Acid Substitution; Antineoplastic Agents; Aspirin; Bone Marrow; Cell Lineage; Cell Trans

2013
Cytoreduction plus low-dose aspirin versus cytoreduction alone as primary prophylaxis of thrombosis in patients with high-risk essential thrombocythaemia: an observational study.
    British journal of haematology, 2013, Volume: 161, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Aspirin; Drug Therap

2013
The therapeutic goals of essential thrombocythemia under the clouds of over-treatment and under-treatment.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:11

    Topics: Aspirin; Fibrinolytic Agents; Humans; Hydroxyurea; Interferon-alpha; Platelet Aggregation Inhibitors

2013
ADP-induced platelet aggregation and thrombin generation are increased in Essential Thrombocythemia and Polycythemia Vera.
    Thrombosis research, 2013, Volume: 132, Issue:1

    Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Female; Humans; Jan

2013
[A preschool child with primary thrombocytosis].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2013, Volume: 51, Issue:7

    Topics: Aspirin; Blood Cell Count; Blood Platelets; C-Reactive Protein; Child, Preschool; Diagnosis, Differe

2013
Aspirin-responsive, migraine-like transient cerebral and ocular ischemic attacks and erythromelalgia in JAK2-positive essential thrombocythemia and polycythemia vera.
    Acta haematologica, 2015, Volume: 133, Issue:1

    Topics: Adult; Aged; Aspirin; Cerebral Cortex; Erythromelalgia; Eye; Female; Follow-Up Studies; Humans; Isch

2015
New and treatment-relevant risk stratification for thrombosis in essential thrombocythemia and polycythemia vera.
    American journal of hematology, 2015, Volume: 90, Issue:8

    Topics: Age Factors; Aged; Aspirin; Drug Administration Schedule; Enzyme Inhibitors; Fibrinolytic Agents; Hu

2015
Qualitative and quantitative modifications of von Willebrand factor in patients with essential thrombocythemia and controlled platelet count.
    Journal of thrombosis and haemostasis : JTH, 2015, Volume: 13, Issue:7

    Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Aged; Amyloid Precursor Protein Secretases; Aspirin;

2015
Clinical and molecular response to interferon-α therapy in essential thrombocythemia patients with CALR mutations.
    Blood, 2015, Dec-10, Volume: 126, Issue:24

    Topics: Adolescent; Adult; Alleles; Aspirin; Calreticulin; Clonal Evolution; Clone Cells; Dioxygenases; DNA

2015
Practice-relevant revision of IPSET-thrombosis based on 1019 patients with WHO-defined essential thrombocythemia.
    Blood cancer journal, 2015, Nov-27, Volume: 5

    Topics: Aspirin; Humans; Janus Kinase 2; Mutation; Risk Factors; Thrombocythemia, Essential; Thrombosis; Wor

2015
Postpartum haemorrhage in a woman with essential thrombocythemia carrying calreticulin mutation: a case report.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2016, Volume: 27, Issue:6

    Topics: Adult; Aspirin; Calreticulin; Female; Fibrinolytic Agents; Humans; Mutation; Postpartum Hemorrhage;

2016
Aspirin, but not clopidogrel, ameliorates vasomotor symptoms due to essential thrombocythemia: A case report.
    Journal of the neurological sciences, 2016, Jun-15, Volume: 365

    Topics: Aspirin; Clopidogrel; Drug Resistance; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; T

2016
Acute pancreatitis as a side effect of anagrelide hydrochloride hydrate: a case report.
    Annals of hematology, 2016, Volume: 95, Issue:11

    Topics: Abdominal Pain; Acute Disease; Aged; Aspirin; Drug Substitution; Female; Humans; Hydroxyurea; Janus

2016
Anagrelide reduces thrombotic risk in essential thrombocythaemia vs. hydroxyurea plus aspirin.
    European journal of haematology, 2017, Volume: 98, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Drug Therapy, Combination; Female; Follow-Up Studies; Human

2017
Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk-stratification, and management.
    American journal of hematology, 2017, Volume: 92, Issue:1

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Erythropoietin; Humans; Hydroxyurea; Interferon-alph

2017
Observational retrospective study of vascular modulator changes during treatment in essential thrombocythemia.
    Translational research : the journal of laboratory and clinical medicine, 2017, Volume: 184

    Topics: Adrenomedullin; Aged; Aspirin; Blood Platelets; Case-Control Studies; Cell-Derived Microparticles; E

2017
Essential thrombocythemia: a case of acute ST-segment elevation myocardial infarction in a young female.
    Clinical cardiology, 2009, Volume: 32, Issue:2

    Topics: Adult; Age Factors; Antisickling Agents; Aspirin; Clopidogrel; Coronary Angiography; Female; Fibrino

2009
Predictors of pregnancy outcome in essential thrombocythemia: a single institution study of 63 pregnancies.
    European journal of haematology, 2009, Volume: 82, Issue:5

    Topics: Abortion, Spontaneous; Adolescent; Adult; Aspirin; Female; Humans; Janus Kinase 2; Leukocyte Count;

2009
[Intradural block in essential thrombocytosis].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:1

    Topics: Aged, 80 and over; Anesthesia, Spinal; Aspirin; Female; Fracture Fixation, Internal; Hematoma, Epidu

2009
Outcome of 122 pregnancies in essential thrombocythemia patients: A report from the Italian registry.
    American journal of hematology, 2009, Volume: 84, Issue:10

    Topics: Adolescent; Adult; Aspirin; Female; Humans; Interferon Type I; Italy; Janus Kinase 2; Middle Aged; M

2009
JAK2V617F mutation-positive childhood essential thrombocythemia associated with cerebral venous sinus thrombosis.
    Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:9

    Topics: Aspirin; Child; Clone Cells; Cytotoxins; Diagnosis, Differential; Female; Headache; Humans; Hydroxyu

2009
Essential thrombocythemia and pregnancy: Observations from recent studies and management recommendations.
    American journal of hematology, 2009, Volume: 84, Issue:10

    Topics: Aspirin; Female; Heparin, Low-Molecular-Weight; Humans; Hydroxyurea; Interferon Type I; Pregnancy; P

2009
Aspirin in pregnant patients with essential thrombocythemia: a retrospective analysis of 129 pregnancies.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:2

    Topics: Aspirin; Female; Genotype; Humans; Janus Kinase 2; Mutation; Phenotype; Platelet Aggregation Inhibit

2010
Management of refractory essential thrombocythemia with anagrelide in a patient undergoing hemodialysis.
    Clinical therapeutics, 2009, Volume: 31, Issue:11

    Topics: Aged; Aspirin; Blood Cell Count; Blood Chemical Analysis; Blood Transfusion; Drug Resistance; Erythr

2009
Evaluation of platelet function and pharmacological platelet inhibition in patients with myeloproliferative disorders using multiple electrode aggregometry.
    Thrombosis research, 2010, Volume: 126, Issue:3

    Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Austria; Case-Control Studies; Clopid

2010
Aspirin in low-risk essential thrombocythemia, not so simple after all?
    Leukemia research, 2011, Volume: 35, Issue:3

    Topics: Aspirin; Humans; Platelet Aggregation Inhibitors; Prognosis; Thrombocythemia, Essential

2011
Thrombocytosis in rheumatoid arthritis: JAK2V617F-positive essential thrombocythemia.
    Rheumatology international, 2012, Volume: 32, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Comorbidity; Humans; Hydroxyurea; Janus Kinase

2012
[Pregnancy and essential thrombocytemia].
    Gynecologie, obstetrique & fertilite, 2011, Volume: 39, Issue:4

    Topics: Adult; Aspirin; Female; Hospitals, University; Humans; Platelet Aggregation Inhibitors; Pregnancy; P

2011
Direct evidence for normalization of platelet function resulting from platelet count reduction in essential thrombocythemia.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2011, Volume: 22, Issue:6

    Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Platelets; Collagen; Epinephrine; Female; Greece; Human

2011
Twice daily aspirin to improve biological aspirin efficacy in patients with essential thrombocythemia.
    Thrombosis research, 2012, Volume: 129, Issue:1

    Topics: Aged; Arachidonic Acid; Aspirin; Drug Administration Schedule; Drug Resistance; Female; Humans; Male

2012
Circulating endothelial cells and endothelial activation in essential thrombocythemia: results from CD146+ immunomagnetic enrichment--flow cytometry and soluble E-selectin detection.
    American journal of hematology, 2012, Volume: 87, Issue:3

    Topics: Alkylating Agents; Anticoagulants; Aspirin; CD146 Antigen; Drug Therapy, Combination; E-Selectin; En

2012
Overcoming "aspirin resistance" in MPN.
    Blood, 2012, Apr-12, Volume: 119, Issue:15

    Topics: Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Female; Humans; Male; Thrombocythemia, Essential; Throm

2012
Two cases of pediatric essential thrombocythemia managed effectively with hydroxyurea.
    International journal of hematology, 2012, Volume: 96, Issue:6

    Topics: Aspirin; Asymptomatic Diseases; Bone Marrow; Child; Child, Preschool; Female; Headache; Humans; Hydr

2012
[Essential thrombocythemia: molecular pathophysiology and treatment].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 2

    Topics: Aspirin; Humans; Janus Kinase 2; Mutation; Thrombocythemia, Essential

2012
Excessive prolongation of the Ivy bleeding time after aspirin in essential thrombocythemia is also demonstrable in vitro in the high shear stress system PFA-100.
    Annals of hematology, 2002, Volume: 81, Issue:6

    Topics: Adult; Aged; Aspirin; Bleeding Time; Female; Hemostasis; Humans; Male; Middle Aged; Platelet Functio

2002
Pregnancy in essential thrombocythemia during aspirin treatment.
    Archives of gynecology and obstetrics, 2003, Volume: 268, Issue:3

    Topics: Adult; Aspirin; Cesarean Section; Drug Administration Schedule; Female; Humans; Infant, Newborn; Mal

2003
Low-dose aspirin in polycythemia vera.
    The New England journal of medicine, 2004, Apr-15, Volume: 350, Issue:16

    Topics: Aspirin; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Polycythemia Vera; Thrombocythemia, Es

2004
Essential thrombocythaemia in children: is a treatment needed?
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:5

    Topics: Adult; Aspirin; Child; Clinical Trials, Phase II as Topic; Humans; Interferon-alpha; Quinazolines; T

2004
When and how to treat essential thrombocythemia.
    The New England journal of medicine, 2005, Jul-07, Volume: 353, Issue:1

    Topics: Antineoplastic Agents; Aspirin; Drug Therapy, Combination; Hemorrhage; Humans; Hydroxyurea; Leukemia

2005
Periodic plateletpheresis during pregnancy in a high-risk patient with essential thrombocythemia.
    Journal of clinical apheresis, 2006, Volume: 21, Issue:4

    Topics: Abortion, Spontaneous; Adult; Anticoagulants; Aspirin; Blood Flow Velocity; Cesarean Section; Female

2006
The use of aspirin and clinical implications in essential thrombocythemia.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Humans; Middle Aged; Platel

2006
Interferon-alfa treatment of essential thrombocythemia during pregnancy.
    Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:20

    Topics: Adult; Anticoagulants; Aspirin; Drug Therapy, Combination; Female; Fetal Diseases; Humans; Immunolog

2006
Platelet-mediated erythromelalgic, cerebral, ocular and coronary microvascular ischemic and thrombotic manifestations in patients with essential thrombocythemia and polycythemia vera: a distinct aspirin-responsive and coumadin-resistant arterial thromboph
    Platelets, 2006, Volume: 17, Issue:8

    Topics: Aged; Anticoagulants; Aspirin; Drug Resistance; Erythromelalgia; Female; Humans; Ischemia; Male; Mic

2006
Essential thrombocythemia in a child with elevated thrombopoietin concentrations and skeletal anomalies.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:4

    Topics: Aspirin; Bone and Bones; Child, Preschool; Enzyme Inhibitors; Female; Humans; Hydroxyurea; Male; Mot

2008
[Case of erythromelalgia due to essential thrombocythemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2007, Volume: 48, Issue:5

    Topics: Aged; Aspirin; Debridement; Diagnosis, Differential; Erythromelalgia; Female; Humans; Hydroxyurea; T

2007
Practical approach to treating essential thrombocythaemia: case studies.
    European journal of haematology. Supplementum, 2007, Issue:68

    Topics: Adult; Aspirin; Disease Management; Female; Humans; Hydroxyurea; Interferon-alpha; Leg Ulcer; Male;

2007
Prevention of thrombosis in polycythemia vera and essential thrombocythemia.
    Haematologica, 2008, Volume: 93, Issue:3

    Topics: Arterial Occlusive Diseases; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans;

2008
Improving the outcome of pregnancy in essential thrombocythaemia: The role of aspirin.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2008, Volume: 28, Issue:2

    Topics: Adult; Aspirin; Female; Humans; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications,

2008
[Primary thrombocythemia in childhood].
    Tijdschrift voor kindergeneeskunde, 1983, Volume: 51, Issue:3

    Topics: Adolescent; Aspirin; Child; Dipyridamole; Drug Therapy, Combination; Female; Humans; Male; Melphalan

1983
[Prevention of vascular complications in polycythemia vera and primary thrombocythemia treated with low doses of acetylsalicylic acid].
    Schweizerische medizinische Wochenschrift, 1983, Nov-05, Volume: 113, Issue:44

    Topics: Aged; Aspirin; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Polycythemia Ver

1983
[Association of hemorrhagic and thrombotic phenomena in myeloproliferative syndromes].
    Medicina, 1981, Volume: 41 Suppl

    Topics: Adult; Aspirin; Blood Platelet Disorders; Dipyridamole; Female; Humans; Leukemia, Myeloid; Male; Mid

1981
[23-year-old patient with abdominal pain, hepatosplenomegaly, ascites and leg edema].
    Der Internist, 1995, Volume: 36, Issue:9

    Topics: Adult; Ascites; Aspirin; Biopsy; Blood Coagulation Tests; Budd-Chiari Syndrome; Combined Modality Th

1995
[Cutaneous manifestations of essential thrombocythemia. Erythromelalgia, ischemic acrocyanosis, livedo racemosa].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1995, Volume: 46, Issue:7

    Topics: Aged; Aspirin; Cyanosis; Diagnosis, Differential; Erythromelalgia; Female; Humans; Ischemia; Skin; T

1995
[Recent trends in therapy of chronic myeloproliferative disorders].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1993, Jul-10, Volume: 82, Issue:7

    Topics: Alkylating Agents; Aspirin; Humans; Hydroxyurea; Interferons; Pipobroman; Prognosis; Thrombocythemia

1993
[A case of pregnancy with essential thrombocythemia].
    Nihon Sanka Fujinka Gakkai zasshi, 1995, Volume: 47, Issue:3

    Topics: Adult; Aspirin; Dipyridamole; Female; Heparin; Humans; Pregnancy; Pregnancy Complications, Hematolog

1995
Platelet consumption in thrombocythemia complicated by erythromelalgia: reversal by aspirin.
    Thrombosis and haemostasis, 1995, Volume: 73, Issue:2

    Topics: Adult; Aged; Aspirin; Blood Platelets; Case-Control Studies; Cell Survival; Erythromelalgia; Female;

1995
Transient neurologic and ocular manifestations in primary thrombocythemia.
    Neurology, 1993, Volume: 43, Issue:6

    Topics: Adult; Aged; Aspirin; Eye Diseases; Female; Humans; Male; Middle Aged; Nervous System Diseases; Plat

1993
[Essential thrombocythemia. Apropos a case of cerebrovascular stroke].
    Acta medica portuguesa, 1993, Volume: 6, Issue:10

    Topics: Aspirin; Cerebrovascular Disorders; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged;

1993
Alpha 2b-interferon therapy and pregnancy--report of a case of essential thrombocythemia.
    American journal of hematology, 1993, Volume: 43, Issue:1

    Topics: Adult; Aspirin; Female; Humans; Infant, Newborn; Infarction; Interferon alpha-2; Interferon-alpha; P

1993
Platelet activation and thrombosis: studies in a patient with essential thrombocythemia.
    American journal of hematology, 1996, Volume: 51, Issue:1

    Topics: Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Aspirin; Blood Platelets; Disease Susceptibili

1996
Essential thrombocythemia and central retinal vein occlusion with neovascular glaucoma.
    American journal of ophthalmology, 1996, Volume: 121, Issue:6

    Topics: Adrenergic beta-Antagonists; Antisickling Agents; Aspirin; Bone Marrow; Fluorescein Angiography; Fun

1996
The reduction of large von Willebrand factor multimers in plasma in essential thrombocythaemia is related to the platelet count.
    British journal of haematology, 1996, Volume: 93, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Female; Humans; Male; Middle Aged; Platelet Count; Thromboc

1996
The paradox of bleeding and thrombosis in thrombocythemia: is von Willebrand factor the link?
    Seminars in thrombosis and hemostasis, 1997, Volume: 23, Issue:4

    Topics: Aged; Alkylating Agents; Aspirin; Erythromelalgia; Female; Fibrinolytic Agents; Hemorrhage; Hemorrha

1997
Aspirin increases the bleeding side effects in essential thrombocythemia independent of the cyclooxygenase pathway: role of the lipoxygenase pathway.
    American journal of hematology, 1998, Volume: 57, Issue:4

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aspirin; Bleeding Time; Blood Coagulation; Humans; Lipox

1998
Acute coronary disease in essential thrombocythemia and polycythemia vera.
    Journal of internal medicine, 1998, Volume: 244, Issue:1

    Topics: Adult; Aged; Aging; Antisickling Agents; Aspirin; Female; Follow-Up Studies; Humans; Hydroxyurea; Ma

1998
Low-risk essential thrombocythaemia in patients younger than 40.
    British journal of haematology, 1999, Volume: 104, Issue:4

    Topics: Adolescent; Adult; Aspirin; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male;

1999
Essential thrombocythemia in young adults: treatment and outcome of 16 pregnancies.
    Journal of internal medicine, 1999, Volume: 246, Issue:5

    Topics: Adult; Aspirin; Female; Humans; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications,

1999
Increased platelet surface expression of P-selectin and thrombospondin as markers of platelet activation in essential thrombocythaemia.
    Thrombosis research, 1999, Nov-01, Volume: 96, Issue:3

    Topics: Aspirin; Blood Platelets; Flow Cytometry; Gene Expression Regulation; Humans; Middle Aged; P-Selecti

1999
Essential thrombocythemia in young adults: major thrombotic complications and complications during pregnancy--a follow-up study in 68 patients.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2000, Volume: 6, Issue:1

    Topics: Acute Disease; Adult; Age Factors; Arteriosclerosis; Aspirin; Busulfan; Cohort Studies; Disease-Free

2000
Pregnancy in essential thrombocythaemia: treatment and outcome of 17 pregnancies.
    European journal of haematology, 2000, Volume: 65, Issue:3

    Topics: Abortion, Spontaneous; Adult; Aspirin; Female; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Pl

2000
Acetylsalicylic acid induced cessation of transient ischaemic attacks and microembolic signals detected by transcranial Doppler in a patient with essential thrombocythaemia.
    Journal of neurology, 2001, Volume: 248, Issue:1

    Topics: Administration, Oral; Aged; Aspirin; Fibrinolytic Agents; Humans; Infusions, Intravenous; Intracrani

2001
Four pregnancies in two patients with essential thrombocythaemia--a case report.
    Annals of the Academy of Medicine, Singapore, 2002, Volume: 31, Issue:3

    Topics: Adult; Aspirin; Combined Modality Therapy; Cyclooxygenase Inhibitors; Female; Fetal Death; Humans; H

2002
Antiplatelet agents in the treatment of thrombotic complications of primary thrombocythemia.
    Canadian Medical Association journal, 1979, Jan-06, Volume: 120, Issue:1

    Topics: Aged; Aspirin; Humans; Male; Sulfinpyrazone; Thrombocythemia, Essential; Thrombosis

1979
[Essential thrombocytosis. Presentation of one case (author's transl)].
    Sangre, 1975, Volume: 20, Issue:1

    Topics: Adult; Aspirin; Busulfan; Humans; Male; Thrombocythemia, Essential

1975
Essential thrombocythemia in pregnancy: platelet count and pregnancy outcome.
    American journal of hematology, 1992, Volume: 41, Issue:4

    Topics: Adult; Aspirin; Female; Humans; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Pre

1992
Reversal of delirium associated with essential thrombocythemia by antiplatelet therapy.
    Psychosomatics, 1992,Spring, Volume: 33, Issue:2

    Topics: Aged; Aspirin; Delirium; Female; Humans; Hydroxyurea; Platelet Aggregation Inhibitors; Platelet Coun

1992
Thrombocythemia and coronary artery disease.
    American heart journal, 1991, Volume: 122, Issue:2

    Topics: Adult; Aged; Aspirin; Busulfan; Coronary Disease; Female; Humans; Male; Middle Aged; Polycythemia Ve

1991
Erythromelalgia versus erythermalgia.
    Lancet (London, England), 1990, Jul-21, Volume: 336, Issue:8708

    Topics: Aspirin; Erythromelalgia; Humans; Raynaud Disease; Thrombocythemia, Essential

1990
Essential thrombocythemia and complications of pregnancy.
    American journal of hematology, 1991, Volume: 36, Issue:3

    Topics: Abortion, Incomplete; Aspirin; Female; Fetal Death; Humans; Pregnancy; Pregnancy Complications, Hema

1991
Essential thrombocythemia in a child: management with anagrelide.
    The American journal of pediatric hematology/oncology, 1991,Spring, Volume: 13, Issue:1

    Topics: Aspirin; Child; Drug Therapy, Combination; Humans; Male; Platelet Aggregation Inhibitors; Platelet C

1991
[Essential thrombocythemia. Case reports and clinico-therapeutic considerations].
    Minerva medica, 1990, Volume: 81, Issue:3

    Topics: Alkylating Agents; Antimetabolites; Aspirin; Bone Marrow; Dipyridamole; Drug Therapy, Combination; H

1990
Aspirin and risk of bleeding in patients with thrombocythemia.
    The American journal of medicine, 1987, Volume: 83, Issue:2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adolescent; Adult; Aged; Aspirin; Bleeding Time; Blood P

1987
Aspirin withdrawal in a patient with essential thrombocythemia: possible cause of myocardial infarction.
    The American journal of medicine, 1987, Volume: 83, Issue:6

    Topics: Aspirin; Coronary Disease; Coronary Thrombosis; Humans; Male; Middle Aged; Myocardial Infarction; Su

1987
Essential thrombocythemia associated with recurrent abortions and fetal growth retardation.
    American journal of hematology, 1987, Volume: 25, Issue:3

    Topics: Abortion, Habitual; Adult; Aspirin; Dipyridamole; Female; Fetal Growth Retardation; Humans; Platelet

1987
Thrombocythaemia and recurrent late abortions: normal outcome of pregnancies after antiaggregatory treatment. Case report.
    British journal of obstetrics and gynaecology, 1986, Volume: 93, Issue:4

    Topics: Abortion, Habitual; Adult; Aspirin; Dipyridamole; Female; Humans; Pregnancy; Pregnancy Trimester, Se

1986
Essential thrombocythaemia and peripheral gangrene.
    British medical journal, 1974, Aug-31, Volume: 3, Issue:5930

    Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Cell Count; Collagen; Gangrene; Humans; Male; Middle Ag

1974
[Action of Aspirin on the vascular manifestations of thrombocythemia].
    Marseille medical, 1972, Volume: 109, Issue:2

    Topics: Aspirin; Blood Platelet Disorders; Epinephrine; Humans; Male; Platelet Adhesiveness; Thrombocythemia

1972