Page last updated: 2024-10-23

aspirin and Hemorrhage, Oral

aspirin has been researched along with Hemorrhage, Oral in 35 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Aspirin is a common, chronically administered preventive treatment for cardiovascular disease, but is often discontinued prior to invasive dental procedures because of concern for bleeding complications."2.73Aspirin use and post-operative bleeding from dental extractions. ( Brennan, MT; Fox, PC; Kent, ML; Lockhart, PB; Napeñas, JJ; Noll, JL; Sasser, HC; Valerin, MA, 2008)
"Thrombosis is of greater overall clinical importance in terms of morbidity and mortality than all of the hemorrhagic disorders combined."2.41Antithrombotic agents: implications in dentistry. ( Henry, RG; Little, JW; McIntosh, BA; Miller, CS, 2002)
"Aspirin was not stopped for a single patient."1.33Minor oral surgery without stopping daily low-dose aspirin therapy: a study of 51 patients. ( Madan, AD; Madan, G; Madan, GA; Madan, SG, 2005)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199012 (34.29)18.7374
1990's4 (11.43)18.2507
2000's9 (25.71)29.6817
2010's10 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akhlaghi, F1
Khaheshi, I2
Amirhassani, S1
Tabrizi, R2
Hoseinzadeh, A1
Rezvanpour, B1
Shafie, S1
Wang, WY1
Cui, NH1
Wang, EB1
Zhang, W1
Bajkin, BV2
Urosevic, IM1
Stankov, KM1
Petrovic, BB2
Bajkin, IA2
Zhao, B1
Wang, P1
Dong, Y1
Zhu, Y1
Zhao, H1
Hanken, H1
Gröbe, A1
Heiland, M1
Smeets, R1
Kluwe, L1
Wikner, J1
Koehnke, R1
Al-Dam, A1
Eichhorn, W1
Sadeghi-Ghahrody, M1
Yousefi-Malekshah, SH1
Karimi-Sari, H1
Yazdanpanah, H1
Rezaee-Zavareh, MS1
Yavarahmadi, M1
Brennan, MT2
Valerin, MA1
Noll, JL1
Napeñas, JJ2
Kent, ML1
Fox, PC1
Sasser, HC1
Lockhart, PB2
Henry, RG2
Hong, CH1
Furney, SL1
Goldhaber, SZ1
Scully, C1
Wolff, A1
Allard, RH1
Baart, JA1
Huijgens, PC1
van Merkesteijn, JP1
Madan, GA1
Madan, SG1
Madan, G1
Madan, AD1
Løkken, P1
Skjelbred, P1
Tjønnfjord, GE1
Wahl, MJ1
Howell, J1
Thomason, JM1
Seymour, RA1
Murphy, P1
Brigham, KM1
Jones, P1
Ardekian, L1
Gaspar, R1
Peled, M1
Brener, B1
Laufer, D1
van der Meer, J1
Little, JW1
Miller, CS1
McIntosh, BA1
McGaul, T1
Pawlak, DF1
Itkin, AB1
Lapeyrolerie, FM1
Zweig, B1
Foulke, CN1
Gardin, M1
Simondi, R1
Teramo, MG1
Gallamini, A1
Steidler, NE1
Minssart, F1
Lemkin, SR1
Billesdon, JE1
Davee, JS1
Leake, DL1
Kattlove, HE1
Hersh, RA1
Kjellman, O1
Quick, AJ1
Bodenbender, RH1
Heimansohn, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Local Hemostatic Management in Implant Surgery in Anticoagulated Patients on Warfarin: a Randomized Clinical Study[NCT04846114]71 participants (Actual)Interventional2016-03-31Completed
A Prospective, Nonrandomized, Study Comparing the Use of Aspirin and Intraoperative Blood Loss and Postoperative Complications Following Open Inguinal Hernia Repair.[NCT02084615]300 participants (Anticipated)Interventional2014-08-31Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for aspirin and Hemorrhage, Oral

ArticleYear
Should aspirin be stopped before tooth extraction? A meta-analysis.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2015, Volume: 119, Issue:5

    Topics: Aspirin; Humans; Oral Hemorrhage; Tooth Extraction

2015
Dental management of patients taking antiplatelet medications.
    Texas dental journal, 2009, Volume: 126, Issue:7

    Topics: Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Dental Care for Chronically Ill; Humans; Oral Hemor

2009
Oral surgery in patients on anticoagulant therapy.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2002, Volume: 94, Issue:1

    Topics: Analgesics; Anti-Infective Agents; Anticoagulants; Aspirin; Dental Care for Chronically Ill; Drug In

2002
[Aspirin, a risk factor for bleeding at dental procedures].
    Nederlands tijdschrift voor tandheelkunde, 1995, Volume: 102, Issue:8

    Topics: Antifibrinolytic Agents; Aspirin; Blood Loss, Surgical; Humans; Intraoperative Complications; Oral H

1995
Antithrombotic agents: implications in dentistry.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2002, Volume: 93, Issue:5

    Topics: Anticoagulants; Aspirin; Blood Coagulation Tests; Clopidogrel; Dental Care; Drug Interactions; Embol

2002

Trials

6 trials available for aspirin and Hemorrhage, Oral

ArticleYear
[Clinical evaluation of influence of aspirin on post-operative bleeding after tooth extraction in the elderly].
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2013, Volume: 48, Issue:5

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Aspirin; Female; Humans; Lidocaine; Male; Middle Aged; O

2013
Aspirin use and post-operative bleeding from dental extractions.
    Journal of dental research, 2008, Volume: 87, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Female; Hemostasis; Humans;

2008
The effects of combined oral anticoagulant-aspirin therapy in patients undergoing tooth extractions: a prospective study.
    Journal of the American Dental Association (1939), 2012, Volume: 143, Issue:7

    Topics: Acenocoumarol; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anticoagulants; Aspirin; Chi-Sq

2012
Does low-dose aspirin therapy complicate oral surgical procedures?
    Journal of the American Dental Association (1939), 2000, Volume: 131, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Female; Humans;

2000
Clinical effects of aspirin and acetaminophen on hemostasis after exodontics.
    Journal of oral surgery (American Dental Association : 1965), 1978, Volume: 36, Issue:12

    Topics: Acetaminophen; Aspirin; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Double-Blind Me

1978
Apernyl as alveolar inlay in connection with the removal of impacted third molars of the lower jaw. A clinical double blind investigation of 100 patients.
    Svensk tandlakare tidskrift. Swedish dental journal, 1973, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Dry Socket; Female; Hematoma; Humans; Male; Ma

1973

Other Studies

24 other studies available for aspirin and Hemorrhage, Oral

ArticleYear
Do antiplatelet drugs increase the risk of bleeding after tooth extraction? A case-crossover study.
    International journal of oral and maxillofacial surgery, 2017, Volume: 46, Issue:11

    Topics: Aspirin; Cell Adhesion Molecules; Clopidogrel; Cross-Over Studies; Female; Flow Cytometry; Humans; M

2017
Do Antiplatelet Drugs Increase the Risk of Bleeding After Dental Implant Surgery? A Case-and-Crossover Study.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2018, Volume: 76, Issue:10

    Topics: Aged; Aspirin; Clopidogrel; Cross-Over Studies; Dental Implantation, Endosseous; Dental Implants; Fe

2018
Dental extractions and risk of bleeding in patients taking single and dual antiplatelet treatment.
    The British journal of oral & maxillofacial surgery, 2015, Volume: 53, Issue:1

    Topics: Absorbable Implants; Aged; Aspirin; Clopidogrel; Collagen; Ecchymosis; Female; Hematoma; Hemostasis,

2015
Postoperative bleeding risk for oral surgery under continued rivaroxaban anticoagulant therapy.
    Clinical oral investigations, 2016, Volume: 20, Issue:6

    Topics: Aged; Anticoagulants; Aspirin; Factor Xa Inhibitors; Female; Humans; Male; Middle Aged; Oral Hemorrh

2016
Bleeding after tooth extraction in patients taking aspirin and clopidogrel (Plavix®) compared with healthy controls.
    The British journal of oral & maxillofacial surgery, 2016, Volume: 54, Issue:5

    Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Oral Hemorrhage; Platelet Aggregation Inhib

2016
Frequency of bleeding following invasive dental procedures in patients on low-molecular-weight heparin therapy.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010, Volume: 68, Issue:5

    Topics: Adolescent; Adult; Aged; Anticoagulants; Antifibrinolytic Agents; Aspirin; Enoxaparin; Female; Gelat

2010
Ask the doctor. I am a 79-year-old man with atrial fibrillation that is well controlled by Pacerone. I also take warfarin and aspirin to prevent stroke. I plan to have a tooth pulled next month and wonder if is is safe to go off the blood thinners. Ho
    Harvard heart letter : from Harvard Medical School, 2010, Volume: 21, Issue:3

    Topics: Aged; Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atrial Fibrillation; Drug Prescriptions; Heal

2010
[Antithrombotic therapy and dental surgery with bleeding].
    Nederlands tijdschrift voor tandheelkunde, 2004, Volume: 111, Issue:12

    Topics: Aspirin; Clopidogrel; Fibrinolytic Agents; Humans; Oral Hemorrhage; Oral Surgical Procedures; Platel

2004
Minor oral surgery without stopping daily low-dose aspirin therapy: a study of 51 patients.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2005, Volume: 63, Issue:9

    Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, Local; Aspirin; Blood Coagulat

2005
[Should warfarin and acetylsalicylic acid be withdrawn prior to tooth extraction?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2005, Sep-22, Volume: 125, Issue:18

    Topics: Anticoagulants; Aspirin; Cyclooxygenase Inhibitors; Fibrinolytic Agents; Humans; Oral Hemorrhage; Pl

2005
[Anticoagulation therapy and oral surgery].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2005, Nov-03, Volume: 125, Issue:21

    Topics: Anticoagulants; Aspirin; Fibrinolytic Agents; Humans; Oral Hemorrhage; Risk Factors; Tooth Extractio

2005
Altering anticoagulation therapy: a survey of physicians.
    Journal of the American Dental Association (1939), 1996, Volume: 127, Issue:5

    Topics: Anticoagulants; Aspirin; Cardiology; Data Collection; Dental Care for Chronically Ill; Family Practi

1996
Aspirin-induced post-gingivectomy haemorrhage: a timely reminder.
    Journal of clinical periodontology, 1997, Volume: 24, Issue:2

    Topics: Adult; Aspirin; Cyclosporine; Dental Care for Chronically Ill; Gingival Hypertrophy; Gingivectomy; H

1997
Postoperative bleeding caused by aspirin.
    Journal of dentistry, 1978, Volume: 6, Issue:3

    Topics: Adult; Aspirin; Humans; Male; Oral Hemorrhage; Periodontium; Postoperative Complications

1978
Gingival hemorrhage related to aspirin ingestion. A case report.
    Journal of periodontology, 1976, Volume: 47, Issue:6

    Topics: Adult; Aspirin; Blood Platelets; Gingival Hemorrhage; Humans; Male; Oral Hemorrhage

1976
Hemorrhage after endosseous implant.
    Journal of the American Dental Association (1939), 1991, Volume: 122, Issue:1

    Topics: Aspirin; Dental Implantation, Endosseous, Endodontic; Humans; Male; Mandibular Injuries; Oral Hemorr

1991
[Thrombocytopathy due to aspirin. A case report].
    Minerva stomatologica, 1986, Volume: 35, Issue:9

    Topics: Adolescent; Aspirin; Blood Platelet Disorders; Hematoma; Humans; Male; Oral Hemorrhage

1986
Aspirin and post-surgical haemorrhage.
    Australian orthodontic journal, 1985, Volume: 9, Issue:2

    Topics: Aspirin; Humans; Oral Hemorrhage; Postoperative Complications; Tooth Extraction

1985
[Blood coagulation disorders of a toxic (alcoholism, drugs, poisoning) or iatrogenic (anticoagulants) nature].
    Revue belge de medecine dentaire. Belgisch tijdschrift voor tandheelkunde, 1972, Volume: 27, Issue:2

    Topics: Alcoholic Intoxication; Analgesics; Anticoagulants; Aspirin; Blood Coagulation Disorders; Blood Coag

1972
Aspirin-induced oral bleeding: correction with platelet transfusion. A reminder.
    Oral surgery, oral medicine, and oral pathology, 1974, Volume: 37, Issue:4

    Topics: Aspirin; Blood Platelets; Blood Transfusion; Hemorrhagic Disorders; Humans; Male; Middle Aged; Oral

1974
A clinical study comparing the incidence of postoperative bleeding in patients using salicylate--containing analgesics versus acetaminophen analgesics.
    The journal of the Bergen County Dental Society. Bergen County Dental Society, 1974, Volume: 40, Issue:5

    Topics: Acetaminophen; Analgesics; Aspirin; Oral Hemorrhage; Surgery, Oral

1974
The Minot-von Willebrand syndrome.
    The American journal of the medical sciences, 1967, Volume: 253, Issue:5

    Topics: Adolescent; Adult; Aspirin; Blood Coagulation Tests; Child; Child, Preschool; Diagnosis, Differentia

1967
Aspirin hazard.
    JAMA, 1971, Feb-22, Volume: 215, Issue:8

    Topics: Aspirin; Child; Hemophilia A; Humans; Male; Oral Hemorrhage; Tooth Extraction

1971
Aspirin and hemophilia.
    Journal of the American Dental Association (1939), 1971, Volume: 83, Issue:5

    Topics: Aspirin; Hemophilia A; Oral Hemorrhage; Tooth Extraction

1971