Page last updated: 2024-10-23

aspirin and Hemorrhage, Intracranial, Traumatic

aspirin has been researched along with Hemorrhage, Intracranial, Traumatic in 12 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Patients who take aspirin and sustain traumatic intracranial hemorrhage (tICH) are often transfused platelets in an effort to prevent bleeding progression."1.62Platelet Reactivity Testing for Aspirin Patients Who Sustain Traumatic Intracranial Hemorrhage. ( Eastman, DK; Pelaez, CA; Sidwell, RA; Spilman, SK; Tang, K, 2021)
"Aspirin has a central role in preventing thromboembolic complications in atherosclerotic conditions."1.38[The effect of platelet transfusion on traumatic intracranial hemorrhage among patients treated with aspirin]. ( Bental, O; Cohen, ZR; Jonas-Kimchi, T; Margalit, N; Patal, R; Ram, Z; Roth, J, 2012)
"Aspirin was found to be protective (OR=0."1.35Prevalence and characteristics of traumatic intracranial hemorrhage in elderly fallers presenting to the emergency department without focal findings. ( Abrams, AP; Gangavati, AS; Kelly, SP; Kiely, DK; Kulchycki, LK; Lipsitz, LA; Mottley, JL; Nathanson, LA; Wolfe, RE, 2009)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's8 (66.67)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Alvikas, J1
Myers, SP1
Wessel, CB1
Okonkwo, DO1
Joseph, B1
Pelaez, C1
Doberstein, C1
Guillotte, AR1
Rosengart, MR1
Neal, MD1
Masic, D1
Kwon, O1
Rech, MA1
Eastman, DK1
Spilman, SK1
Tang, K1
Sidwell, RA1
Pelaez, CA1
Lee, AT1
Gagnidze, A1
Pan, SR1
Sookplung, P1
Nair, B1
Newman, SF1
Ben-Ari, A1
Zaky, A1
Cain, K1
Vavilala, MS1
Rozet, I1
Pandya, U1
Malik, A1
Messina, M1
Albeiruti, AR1
Spalding, C1
Briggs, A1
Gates, JD1
Kaufman, RM1
Calahan, C1
Gormley, WB1
Havens, JM1
Thaler, HW1
Schmidsfeld, J1
Pusch, M1
Pienaar, S1
Wunderer, J1
Pittermann, P1
Valenta, R1
Gleiss, A1
Fialka, C1
Mousavi, M1
Gangavati, AS1
Kiely, DK1
Kulchycki, LK1
Wolfe, RE1
Mottley, JL1
Kelly, SP1
Nathanson, LA1
Abrams, AP1
Lipsitz, LA1
Inamasu, J1
Nakatsukasa, M1
Miyatake, S1
Hirose, Y1
Patal, R1
Jonas-Kimchi, T1
Margalit, N1
Ram, Z1
Bental, O1
Cohen, ZR1
Roth, J1
Nishijima, DK1
Zehtabchi, S1
Berrong, J1
Legome, E1
Batchelor, JS1
Grayson, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Post-Injury Platelet Biology: Mechanisms and Outcomes[NCT03682757]367 participants (Actual)Observational2018-09-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for aspirin and Hemorrhage, Intracranial, Traumatic

ArticleYear
A systematic review and meta-analysis of traumatic intracranial hemorrhage in patients taking prehospital antiplatelet therapy: Is there a role for platelet transfusions?
    The journal of trauma and acute care surgery, 2020, Volume: 88, Issue:6

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Disease Progression; Humans; Intracranial Hemorrhage,

2020
Utility of platelet transfusion in adult patients with traumatic intracranial hemorrhage and preinjury antiplatelet use: a systematic review.
    The journal of trauma and acute care surgery, 2012, Volume: 72, Issue:6

    Topics: Adult; Aspirin; Clopidogrel; Cohort Studies; Emergency Service, Hospital; Evidence-Based Medicine; F

2012
A meta-analysis to determine the effect of preinjury antiplatelet agents on mortality in patients with blunt head trauma.
    British journal of neurosurgery, 2013, Volume: 27, Issue:1

    Topics: Aged; Anticoagulants; Aspirin; Blood Coagulation Disorders; Clopidogrel; Epidemiologic Methods; Head

2013

Trials

1 trial available for aspirin and Hemorrhage, Intracranial, Traumatic

ArticleYear
Platelet dysfunction and platelet transfusion in traumatic brain injury.
    The Journal of surgical research, 2015, Volume: 193, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelet Disorders; Female; Humans; Intracranial Hemorrhage,

2015

Other Studies

8 other studies available for aspirin and Hemorrhage, Intracranial, Traumatic

ArticleYear
Desmopressin with four-factor prothrombin complex concentrate for life-threatening bleeding: A case series.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:12

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Coagulation Factors; Cerebral Hemorrhage, Tr

2020
Platelet Reactivity Testing for Aspirin Patients Who Sustain Traumatic Intracranial Hemorrhage.
    The Journal of surgical research, 2021, Volume: 263

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Coagulation Tests; Disease Progression; Female; Humans; Intr

2021
Preoperative Low-Dose Aspirin Exposure and Outcomes After Emergency Neurosurgery for Traumatic Intracranial Hemorrhage in Elderly Patients.
    Anesthesia and analgesia, 2017, Volume: 125, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Elective Surgical Procedures; Emergency Treatment; Female; Glasgow

2017
Reversal of antiplatelet therapy in traumatic intracranial hemorrhage: Does timing matter?
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2018, Volume: 50

    Topics: Adult; Aged; Aspirin; Clopidogrel; Female; Glasgow Coma Scale; Hematoma, Subdural; Humans; Intracran

2018
Evaluation of S100B in the diagnosis of suspected intracranial hemorrhage after minor head injury in patients who are receiving platelet aggregation inhibitors and in patients 65 years of age and older.
    Journal of neurosurgery, 2015, Volume: 123, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Biomarkers; Clopidogrel; Craniocerebral Trauma; Female; Gla

2015
Prevalence and characteristics of traumatic intracranial hemorrhage in elderly fallers presenting to the emergency department without focal findings.
    Journal of the American Geriatrics Society, 2009, Volume: 57, Issue:8

    Topics: Accidental Falls; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Chi-Square Distribution; Clopido

2009
Influence of warfarin and low-dose aspirin on the outcomes of geriatric patients with traumatic intracranial hemorrhage resulting from ground-level fall.
    Geriatrics & gerontology international, 2012, Volume: 12, Issue:4

    Topics: Accidental Falls; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Chi-Square Distribution; Female;

2012
[The effect of platelet transfusion on traumatic intracranial hemorrhage among patients treated with aspirin].
    Harefuah, 2012, Volume: 151, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Female; Head Injuries, Closed; Hematoma, Subdural, Acute; Humans;

2012