aspirin has been researched along with Hematemesis in 49 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Hematemesis: Vomiting of blood that is either fresh bright red, or older coffee-ground in character. It generally indicates bleeding of the UPPER GASTROINTESTINAL TRACT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "96) as well as history of hematemesis, melena in the past 30 days, positive nasogastric aspirate, prior upper gastrointestinal bleeding or use of aspirin or non-steroidal anti-inflammatory." | 3.83 | Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics. ( Camus, M; Dulai, GS; Ghassemi, KA; Jensen, DM; Jutabha, R; Khungar, V; Kovacs, TO; Machicado, GA; Ohning, GV, 2016) |
| "In 674 upper gastrointestinal bleeders, we found that the odds ratio for the presence of erosive oesophagitis in aspirin users was 2 (95% CI, 1-3; P = 0." | 3.73 | Upper gastrointestinal mucosal abnormalities and blood loss complicating low-dose aspirin and antithrombotic therapy. ( Angerson, WJ; Blatchford, O; Knill-Jones, RP; Taha, AS, 2006) |
| "A comparison of aspirin and acetaminophen consumption in 346 matched pairs of patients with hematemesis and melena and general population control subjects has shown associations between intake of both drugs and bleeding." | 3.66 | Analgesic intake and the risk of acute upper gastrointestinal bleeding. ( Coggon, D; Langman, MJ; Spiegelhalter, D, 1983) |
| " The findings of this study are comparable to those of other studies and it is concluded that tolfenamic acid, in the relatively high dosage employed in this trial, is free from any irritant effect on the gastric mucosa." | 2.64 | Comparative effects of tolfenamic acid and acetylsalicylic acid on human gastric mucosa. A double-blind crossover trial employing gastroscopy, extern gastrocamera and multiple biopsies. ( Axelsson, CK; Christiansen, LV; Johansen, A; Poulsen, PE, 1977) |
| "Gastroduodenal ulcers were found in 94 (44%) of the patients; two thirds of the users and one third of the non-users." | 1.29 | [Use of acetylsalicylic acid and other antiphlogistics in hematemesis/melena]. ( Aabakken, L; Breckan, RK, 1994) |
| "The patient was predisposed by previous pyloric stenosis." | 1.26 | Pyloric obstruction caused by aspirin: case report. ( Sherry, E, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (73.47) | 18.7374 |
| 1990's | 5 (10.20) | 18.2507 |
| 2000's | 2 (4.08) | 29.6817 |
| 2010's | 6 (12.24) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mousavi, M | 1 |
| Salehimarzijarani, B | 1 |
| Dadvar, Z | 1 |
| Jalalay, NY | 1 |
| Valizadeh, N | 1 |
| Sotoudeh, H | 1 |
| Zali, M | 1 |
| García Martos, E | 1 |
| García Guerrero, T | 1 |
| Carro Rossell, J | 1 |
| Jiménez Jaén, C | 1 |
| Telaku, S | 1 |
| Kraja, B | 1 |
| Qirjako, G | 1 |
| Prifti, S | 1 |
| Fejza, H | 1 |
| Camus, M | 1 |
| Khungar, V | 1 |
| Jensen, DM | 1 |
| Ohning, GV | 1 |
| Kovacs, TO | 1 |
| Jutabha, R | 1 |
| Ghassemi, KA | 1 |
| Machicado, GA | 1 |
| Dulai, GS | 1 |
| Zimmer, V | 1 |
| Lammert, F | 1 |
| Hara, H | 1 |
| Sakai, E | 1 |
| Inokuchi, Y | 1 |
| Iida, H | 1 |
| Endo, H | 1 |
| Hosono, K | 1 |
| Akiyama, T | 1 |
| Sakamoto, Y | 1 |
| Takahashi, H | 1 |
| Koide, T | 1 |
| Tokoro, C | 1 |
| Inamori, M | 1 |
| Abe, Y | 1 |
| Nakajima, A | 1 |
| Chitose, T | 1 |
| Hokimoto, S | 1 |
| Oshima, S | 1 |
| Nakao, K | 1 |
| Fujimoto, K | 1 |
| Miyao, Y | 1 |
| Shimomura, H | 1 |
| Tsunoda, R | 1 |
| Maruyama, H | 1 |
| Hirose, T | 1 |
| Yamamoto, K | 1 |
| Mizobe, M | 1 |
| Kaikita, K | 1 |
| Nakamura, S | 1 |
| Ogawa, H | 1 |
| EDELMANN, G | 1 |
| WOOD, PH | 1 |
| DIXON, AS | 1 |
| KHOSLA, SN | 1 |
| GEOFFROY, H | 1 |
| JENNINGS, GH | 1 |
| Taha, AS | 1 |
| Angerson, WJ | 1 |
| Knill-Jones, RP | 1 |
| Blatchford, O | 1 |
| Langman, MJ | 5 |
| Coggon, D | 2 |
| Spiegelhalter, D | 2 |
| Booker, JA | 1 |
| Galanda, V | 1 |
| Visnovský, P | 1 |
| Buchanec, J | 1 |
| Cahuana, A | 1 |
| Trías, E | 1 |
| Oliva, F | 1 |
| Youssef, W | 1 |
| Pou, J | 1 |
| Vilar, P | 1 |
| Varea, V | 1 |
| Breckan, RK | 1 |
| Aabakken, L | 1 |
| Symmons, DP | 1 |
| Kelly, JP | 1 |
| Kaufman, DW | 1 |
| Jurgelon, JM | 1 |
| Sheehan, J | 1 |
| Koff, RS | 1 |
| Shapiro, S | 1 |
| Remskar, M | 1 |
| Mozina, H | 1 |
| Noc, M | 1 |
| Zorman, D | 1 |
| Stepec, S | 1 |
| Sherry, E | 1 |
| Shirley, E | 1 |
| Falaiye, JM | 1 |
| Odutola, TA | 1 |
| Axelsson, CK | 1 |
| Christiansen, LV | 1 |
| Johansen, A | 1 |
| Poulsen, PE | 1 |
| Cooke, AR | 1 |
| Domellöf, L | 1 |
| Sönne, B | 1 |
| John, DJ | 1 |
| Coffey, G | 1 |
| Wilson, CW | 1 |
| Holman, RA | 1 |
| Davis, M | 1 |
| Gough, KR | 1 |
| Gartell, P | 1 |
| Britton, DC | 1 |
| Smith, RB | 1 |
| Aluwihare, AP | 1 |
| Karalliedde, LD | 1 |
| Johnston, SJ | 1 |
| Jones, PF | 1 |
| Kyle, J | 1 |
| Needham, CD | 1 |
| Timaffy, M | 1 |
| Búzás, J | 1 |
| Marshall, N | 1 |
| Kuzemko, JA | 1 |
| Nand, UP | 1 |
| Kelner, S | 1 |
| Ferraz, E | 1 |
| Wanderley, F | 1 |
| Horwich, L | 1 |
| Evans, DA | 1 |
| McConnell, RB | 1 |
| Donohoe, WT | 1 |
| Valman, HB | 1 |
| Parry, DJ | 1 |
| Coghill, NF | 1 |
| Benhamou, JP | 1 |
| Debray, C | 1 |
| Hamburger, J | 1 |
| Loygue, J | 1 |
| Roux, M | 1 |
| Pequignot, H | 1 |
| Ferguson, CC | 1 |
| Mathur, SN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sclerotherapy With Polidocanol Foam in the Treatment of First, Second and Third-Grade Hemorrhoidal Disease in Patients With Liver Cirrhosis: A Prospective, Cohort Trial[NCT05807425] | Phase 2/Phase 3 | 40 participants (Anticipated) | Interventional | 2023-03-31 | Recruiting | ||
| Video Capsule Endoscopy for Lesion Localization and Diagnosis in Patients With Severe Hematochezia[NCT03616041] | 50 participants (Anticipated) | Observational | 2021-02-10 | Recruiting | |||
| Gastrointestinal Ulceration in Patients on Dual Antiplatelet Therapy After Percutaneous Coronary Intervention[NCT00413309] | 30 participants (Anticipated) | Interventional | 2006-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for aspirin and Hematemesis
| Article | Year |
|---|---|
The role of the mucosal barrier in drug-induced gastric ulceration and erosions.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Ethanol; Gastric Juice; Gastric Mucosa; | 1976 |
Gastric mucosal damage by aspirin.
Topics: Anemia, Hypochromic; Animals; Aspirin; Cats; Dogs; Ferrets; Gastric Juice; Gastric Mucins; Gastric M | 1975 |
Aspirin, other anti-inflammatory drugs and haematemesis and melaena.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Hematemesis; Humans; Melena; United Kingdom; Unite | 1988 |
Epidemiological evidence for the association of aspirin and acute gastrointestinal bleeding.
Topics: Alcohol Drinking; Animals; Ascorbic Acid Deficiency; Aspirin; Gastrointestinal Hemorrhage; Hematemes | 1970 |
2 trials available for aspirin and Hematemesis
| Article | Year |
|---|---|
Risk of aspirin-associated major upper-gastrointestinal bleeding with enteric-coated or buffered product.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Buffers; Case-Control Stu | 1996 |
Comparative effects of tolfenamic acid and acetylsalicylic acid on human gastric mucosa. A double-blind crossover trial employing gastroscopy, extern gastrocamera and multiple biopsies.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Clinical Trials as Topic; Female; G | 1977 |
43 other studies available for aspirin and Hematemesis
| Article | Year |
|---|---|
Relationship between continuous use of low-dose enteric-coated aspirin and gastrointestinal injuries in patients with gastrointestinal hemorrhage.
Topics: Aspirin; Case-Control Studies; Duodenal Ulcer; Endoscopy, Gastrointestinal; Female; Gastrointestinal | 2013 |
[Hematemesis in an 80-year-old patient with chest pain and nausea].
Topics: Aged, 80 and over; Aspirin; Chest Pain; Clopidogrel; Esophageal Diseases; Esophagoscopy; Female; Hem | 2015 |
Clinical outcomes of nonvariceal upper gastrointestinal bleeding in Kosova.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; An | 2014 |
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont | 2016 |
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont | 2016 |
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont | 2016 |
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont | 2016 |
Clinical images: Multiple esophageal submucosal hematomas.
Topics: Aged; Anticoagulants; Aspirin; Chest Pain; Esophageal Diseases; Esophagoscopy; Female; Hematemesis; | 2010 |
Dissecting intramural hematoma of the esophagus in a Kendo player taking low-dose aspirin.
Topics: Aged; Anticoagulants; Aspirin; Athletes; Esophageal Diseases; Esophagoscopy; Hematemesis; Hematoma; | 2009 |
Clinical outcomes following coronary stenting in Japanese patients treated with and without proton pump inhibitor.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Asian People; Aspirin; Clopidogrel; Coronar | 2012 |
[Severe hematemesis caused by acute gastric ulceration following massive absorption of aspirin].
Topics: Aspirin; Hematemesis; Humans; Stomach Diseases; Stomach Ulcer | 1959 |
"Alka-seltzer" and haematemesis.
Topics: Aspirin; Citrates; Drug Combinations; Hematemesis; Humans; Salicylic Acid; Sodium Bicarbonate | 1963 |
ASPIRIN-INDUCED HAEMATEMESIS.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hematemesis; Hemorrhage; Humans; Melena; Toxicology | 1964 |
[HEMATEMESIS DUE TO DRUGS].
Topics: Adrenal Cortex Hormones; Aspirin; Hematemesis; Phenylbutazone; Reserpine; Toxicology | 1964 |
CAUSAL INFLUENCES IN HAEMATEMESIS AND MELAENA.
Topics: Alcoholic Beverages; Arteriosclerosis; Aspirin; Blood Group Antigens; Duodenal Ulcer; Genetics, Medi | 1965 |
Upper gastrointestinal mucosal abnormalities and blood loss complicating low-dose aspirin and antithrombotic therapy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Dipyrida | 2006 |
Analgesic intake and the risk of acute upper gastrointestinal bleeding.
Topics: Acetaminophen; Analgesics; Aspirin; Female; Gastrointestinal Hemorrhage; Hematemesis; Humans; Male; | 1983 |
Haematemesis and melaena in the elderly.
Topics: Aged; Alcohol Drinking; Anti-Inflammatory Agents; Aspirin; Esophagitis; Female; Gastritis; Hematemes | 1984 |
[Hematemesis and melena in children after administration of salicylates (author's transl)].
Topics: Aspirin; Child; Female; Gastrointestinal Hemorrhage; Hematemesis; Humans; Infant; Male; Melena | 1981 |
[Hematemesis in childhood. Use of the fiberscope in diagnosis].
Topics: Adolescent; Aspirin; Child; Child, Preschool; Duodenitis; Endoscopy; Esophagitis; Female; Fiber Opti | 1982 |
Aspirin, paracetamol, and haematemesis and melaena.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Female; Hematemesis; Humans; Male; Melena; Middle A | 1982 |
[Use of acetylsalicylic acid and other antiphlogistics in hematemesis/melena].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dyspepsia; Female; Hemate | 1994 |
Safety profile of low-dose aspirin.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hematemesis; Humans; Middle Aged; Platelet Aggregation Inhibit | 1996 |
Acute myocardial infarction-failed thrombolysis followed by severe upper gastrointestinal bleeding.
Topics: Aspirin; Fibrinolytic Agents; Follow-Up Studies; Hematemesis; Heparin; Humans; Male; Middle Aged; My | 1999 |
Pyloric obstruction caused by aspirin: case report.
Topics: Aged; Aspirin; Female; Hematemesis; Humans; Pyloric Stenosis; Tablets, Enteric-Coated | 1979 |
A review of papers purporting to show a cause-and-effect relationship between aspirin ingestion and massive gastrointestinal haemorrhage.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hematemesis; Humans; Melena; Time Factors | 1977 |
The economic potential and the role of aspirin and alcohol ingestion in relation to haematemesis and meleana.
Topics: Adult; Aged; Aspirin; Ethanol; Female; Gastrointestinal Hemorrhage; Hematemesis; Humans; Male; Melen | 1978 |
[Serum salicylates in gastrointestinal hemorrhage].
Topics: Acute Disease; Adolescent; Adult; Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Hematemesis; H | 1976 |
Letter: Ascorbic acid deficiency and aspirin-induced haematemesis.
Topics: Ascorbic Acid Deficiency; Aspirin; Gastric Mucosa; Hematemesis; Humans; Platelet Aggregation | 1975 |
Value of a centralised approach in the management of haematemesis and melaena: experience in a district general hospital.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Femal | 1990 |
Leiomyoma of the duodenum presenting with haemorrhage after aspirin ingestion.
Topics: Adult; Aspirin; Duodenal Neoplasms; Female; Hematemesis; Humans; Leiomyoma; Melena | 1988 |
Aspirin and the blood.
Topics: Anemia, Aplastic; Aspirin; Gastric Mucosa; Hematemesis; Hemophilia A; Humans; Substance-Related Diso | 1966 |
Faecal blood-loss after sodium acetylsalicylate taken with alcohol.
Topics: Aspirin; Drug Synergism; Ethanol; Gastrointestinal Hemorrhage; Hematemesis; Humans; Melena; Occult B | 1969 |
Epidemiology and course of gastrointestinal haemorrhage in North-east Scotland.
Topics: Adult; Aged; Alcohol Drinking; Aspirin; Blood Group Antigens; Duodenal Ulcer; Female; Gastritis; Gas | 1973 |
Letter: Naproxen (naprosyn) and gastrointestinal haemorrhage.
Topics: Acetanilides; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Blood Transfusion; Female; Gastritis; | 1974 |
[Recurrent gastric hemorrhage caused by salicylic acid].
Topics: Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Hematemesis; Humans; Male; Melena | 1974 |
Aspirin and haematemesis in children.
Topics: Aspirin; Child; Child, Preschool; Female; Hematemesis; Humans; Male; Medical History Taking; Substan | 1972 |
A case study: haematemesis and melaena following aspirin administration.
Topics: Aspirin; Hematemesis; Melena; Nursing | 1970 |
[Hematemesis: study on its causation by drugs containing acetylsalicylic acid in schistosomotic portal hypertension].
Topics: Adolescent; Adult; Aged; Aspirin; Child; Child, Preschool; Esophageal and Gastric Varices; Female; H | 1966 |
ABO blood groups in gastric bleeding.
Topics: ABO Blood-Group System; Adult; Aspirin; Blood Group Antigens; Duodenal Ulcer; Female; Gastric Mucosa | 1966 |
Lesions associated with gastroduodenal haemorrhage, in relation to aspirin intake.
Topics: Adult; Aged; Aspirin; Duodenal Ulcer; Gastrointestinal Hemorrhage; Gastroscopy; Hematemesis; Humans; | 1968 |
[Procedure to follow in case of severe hematemesis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Blood Transfusion; Blood Volume Determin | 1969 |
Discussion on clinical trials of the fenamates.
Topics: Analgesia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Central Nervous System; Flufena | 1966 |
Susceptibility to aspirin bleeding.
Topics: Alcohols; Anemia, Hypochromic; Aspirin; Gastric Juice; Gastric Mucosa; Gastrointestinal Hemorrhage; | 1970 |
Management of portal hypertension in children.
Topics: Aspirin; Child, Preschool; Esophageal and Gastric Varices; Hematemesis; Humans; Hypertension, Portal | 1968 |
Aspirin-haematemesis.
Topics: Aspirin; Child; Hematemesis; Humans; Male | 1969 |