Page last updated: 2024-10-23

aspirin and Heart Valve Diseases

aspirin has been researched along with Heart Valve Diseases in 76 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).

Research Excerpts

ExcerptRelevanceReference
"When myocardial infarction is due to coronary embolism from endocarditic valves standard thrombolysis regimes should be avoided."5.29Acute coronary embolism complicating aortic valve endocarditis treated with streptokinase and aspirin. A case report. ( Connolly, DL; Crowley, JJ; Dardas, PS; Kenny, A; Petch, MC, 1994)
"Five previously suspected risk factors (valve surgery, prior protamine exposure, history of pulmonary hypertension, fish allergy, and vasectomy), aspirin ingestion within 7 days of surgery, and demographic information were recorded."5.10Effect of site of venous protamine administration, previously alleged risk factors, and preoperative use of aspirin on acute protamine-induced pulmonary vasoconstriction. ( Comunale, ME; Haering, JM; Lowenstein, E; Mashikian, JS; Maslow, A; Robertson, LK, 2003)
"Plasma anticoagulation with warfarin during the early postoperative phase was shown statistically to be inferior to platelet aggregation inhibition by aspirin with regards to postoperative bleeding risk, cerebral ischemic events, and survival."3.83Anticoagulation After Biological Aortic Valve Replacement: Is There An Optimal Regimen? ( Breuer, M; Fuchs, J; Hüter, L; Kuntze, T; Lauer, B; Owais, T; Rouman, M, 2016)
" In patients with patent foramen ovale (PFO) and stroke or transient ischemic attack, we recommend initial aspirin therapy (Grade 1B) and suggest substitution of VKA if recurrence (Grade 2C)."3.78Antithrombotic and thrombolytic therapy for valvular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. ( Fremes, SE; Rubens, FD; Sun, JC; Teoh, KH; Whitlock, RP, 2012)
"This prospective audit reports pregnancy outcomes, anticoagulation complications, and anti-Xa levels in women with mechanical heart valves who were treated with therapeutic enoxaparin plus aspirin during pregnancy."3.71Enoxaparin treatment in women with mechanical heart valves during pregnancy. ( McCowan, LM; North, RA; Raudkivi, PJ; Rowan, JA, 2001)
"The risk of early recurrence of embolism in the first 30 days ranges from 8 to 15%."2.38[Embolic complications of chronic atrial fibrillation]. ( Brechenmacher, C; Chauvin, M; Koenig, A; Théolade, R, 1992)
"Minor bleedings were observed in 19 (17."1.91[Comparison of Various Regimens of Antithrombotic Therapy in Patients With Valvular Heart Disease and Coronary Artery Disease After Surgical and Interventional Interventions]. ( Berdibekov, BS; Bulaeva, NI; Golukhova, EZ; Kubova, MC; Ruzina, EV, 2023)
"Aspirin has been shown to decrease postoperative CABG mortality and ischemic events."1.38Effect of timing of chronic preoperative aspirin discontinuation on morbidity and mortality in patients having combined coronary artery bypass grafting and valve surgery. ( Blackstone, E; Cho, L; Jacob, M; Smedira, N; Williams, S, 2012)
"When myocardial infarction is due to coronary embolism from endocarditic valves standard thrombolysis regimes should be avoided."1.29Acute coronary embolism complicating aortic valve endocarditis treated with streptokinase and aspirin. A case report. ( Connolly, DL; Crowley, JJ; Dardas, PS; Kenny, A; Petch, MC, 1994)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199024 (31.58)18.7374
1990's14 (18.42)18.2507
2000's16 (21.05)29.6817
2010's18 (23.68)24.3611
2020's4 (5.26)2.80

Authors

AuthorsStudies
Granath, C1
Freiholtz, D1
Bredin, F1
Olsson, C1
Franco-Cereceda, A1
Björck, HM1
Ruzina, EV1
Berdibekov, BS1
Bulaeva, NI1
Kubova, MC1
Golukhova, EZ1
Gryaznov, AA1
Saeyeldin, A1
Abdelbaky, M1
Zafar, MA1
Tanweer, M1
Papanikolaou, D1
Imran, M1
Li, Y1
Ziganshin, BA1
Elefteriades, JA1
Smilowitz, NR1
Berger, JS1
Mahajan, K1
Negi, P1
Merwaha, R1
Sharma, M1
Baumann Kreuziger, L1
Karkouti, K1
Tweddell, J1
Massicotte, MP1
Jiang, Z1
Elkind, M1
Lucky, M1
Fekete, Z1
Suri, RM1
Thourani, VH1
He, X1
Brennan, JM1
O'Brien, SM1
Rankin, JS1
Schaff, HV1
Gammie, JS1
Trenson, S1
de Ceuninck, M1
Riaz, H1
Alansari, SA1
Khan, MS1
Riaz, T1
Raza, S1
Luni, FK1
Khan, AR1
Riaz, IB1
Krasuski, RA1
Windecker, S1
Tijssen, J1
Giustino, G1
Guimarães, AH1
Mehran, R1
Valgimigli, M1
Vranckx, P1
Welsh, RC1
Baber, U1
van Es, GA1
Wildgoose, P1
Volkl, AA1
Zazula, A1
Thomitzek, K1
Hemmrich, M1
Dangas, GD1
Owais, T1
Rouman, M1
Breuer, M1
Hüter, L1
Fuchs, J1
Lauer, B1
Kuntze, T1
Moreno, R1
Payanam Ramachandra, U1
Shenoy, SJ1
Arumugham, S1
Salem, DN2
O'Gara, PT1
Madias, C1
Pauker, SG2
Csiba, L1
Kovács, KR1
Eisen, DP1
Corey, GR1
McBryde, ES1
Fowler, VG1
Miro, JM1
Cabell, CH1
Street, AC1
Paiva, MG1
Ionac, A1
Tan, RS1
Tribouilloy, C1
Pachirat, O1
Jones, SB1
Chipigina, N1
Naber, C1
Pan, A1
Ravasio, V1
Gattringer, R1
Chu, VH1
Bayer, AS1
ElBardissi, AW1
DiBardino, DJ1
Chen, FY1
Yamashita, MH1
Cohn, LH1
Colli, A2
D'Amico, R1
Mestres, CA1
Pomar, JL1
Cámara, ML1
Ruyra, X1
Mulet, J1
Gendlin, GE1
Tronina, OA1
Storozhakov, GI1
Jacob, M1
Smedira, N1
Blackstone, E1
Williams, S1
Cho, L1
Whitlock, RP1
Sun, JC1
Fremes, SE1
Rubens, FD1
Teoh, KH1
Oliveira, LH1
Mallmann, FB1
Botelho, FN1
Paul, LC1
Gianotto, M1
Abt, Rde B1
Silva, NJ1
Luize, CM1
Nogueira, FL1
Carvalho, RS1
Paola, AA1
Cirenza, C1
Tzeng, SS1
Liou, JT1
Petricevic, M1
Biocina, B1
Gasparovic, H1
Ivancan, V1
Comunale, ME1
Maslow, A1
Robertson, LK1
Haering, JM1
Mashikian, JS1
Lowenstein, E1
CLARK, EJ1
HOUSER, HB1
PIERAGNOLI, E1
CASA, G1
ZHELEZNOVA, AI1
Gherli, T1
Nicolini, F1
Stein, PD1
Al-Ahmad, A1
Bussey, HI1
Horstkotte, D1
Miller, N1
Minola, E1
Arosio, M1
Rizzo, G1
Passerini Tosi, C1
Suter, F1
Goglio, A1
Vaughan, P1
Waterworth, PD1
García-Rinaldi, R1
Laurent, M1
Lelong, B1
Lenormand, C1
De Place, C1
Matali, P1
Leurent, G1
Verhoye, JP1
Almange, C1
Leguerrier, A1
Descarries, LM1
Leduc, L1
Khairy, P1
Mercier, LA1
Hori, M1
Weinstein, GS1
Mavroudis, C1
Ebert, PA1
de Boer, AC1
Genton, E2
Turpie, AG3
Harris, R1
Crowley, DC1
Fuster, V3
Chesebro, JH1
Warlow, CP1
Toyohira, H1
Nakamura, K1
Kariyazono, H1
Yamada, K1
Moriyama, Y1
Shimokawa, S1
Saigenji, H1
Taira, A1
Yankah, AC1
Alexi-Meskhishvili, V1
Weng, Y1
Berger, F1
Lange, P1
Hetzer, R1
Yamak, B1
Sener, E1
Kiziltepes, U1
Gol, K1
Tarcan, O1
Mavitas, B1
Tasdemir, O1
Bayazit, K1
Connolly, DL1
Dardas, PS1
Crowley, JJ1
Kenny, A1
Petch, MC1
Asherson, RA1
Cervera, R1
Albertal, J1
Sutton, M1
Pereyra, D1
Segura, EV1
Aramburu, DF1
Lardani, H1
Diaz, R1
Malaterre, HR1
Daver, L1
Djiane, P1
Boon, A1
Lodder, J1
Cheriex, E1
Kessels, F1
Gershlick, AH1
Manning, WJ1
Goldsmith, I1
Lip, GY1
Mukundan, S1
Rosin, MD1
Laffort, P1
Roudaut, R1
Roques, X1
Lafitte, S1
Deville, C1
Bonnet, J1
Baudet, E1
Rowan, JA1
McCowan, LM1
Raudkivi, PJ1
North, RA1
Prisco, D1
Salazar Mena, J1
García Moya, JB1
Felipe Villaverde, J1
García de la Calzada, MD1
Didisheim, P2
Hirsh, J2
Trufanova, AV1
Kuz'mina, NN1
Glazkova, TG1
Dale, J2
Myhre, E1
Reich, DL1
Hammerschlag, BC1
Rand, JH1
Perucho-Powell, MH1
Thys, DM1
Koenig, A1
Théolade, R1
Chauvin, M1
Brechenmacher, C1
Toshima, H1
Tanabe, A1
Deans, KW1
Hartshorn, JC1
Nuñez, L1
Pinto, AG1
Larrea, JL1
Gil Aguado, M1
Connor, FO1
Nitter-Hauge, S1
Kingdon, HS1
Isom, OW1
Williams, CD1
Falk, EA1
Spencer, FC1
Glassman, E1
Tahernia, AC1
Moatamed, F1
Sharif, H1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
REACTIC-TAVI Trial: Platelet REACtivity According to TICagrelor Dose After Transcatheter AorticValve Implantation. A Pilot Study.[NCT04331145]Phase 440 participants (Actual)Interventional2020-06-23Completed
Global Multicenter, Open-label, Randomized, Event-driven, Active-controlled Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement (TAVR) to Optimize Clinical Outcomes[NCT02556203]Phase 31,653 participants (Actual)Interventional2015-12-16Terminated (stopped due to Imbalance in the efficacy and safety endpoints between treatment arms in favor of comparator)
Observatory of Anticoagulation After Bioprosthetic Aortic Valve Replacement[NCT01293188]434 participants (Actual)Observational2011-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Cardiovascular Death or Thromboembolic Event

Composite of CV-death, any stroke, myocardial infarction (MI), symptomatic valve thrombosis, pulmonary embolism (PE), deep vein thrombosis (DVT), and non-central nervous system (CNS) systemic embolism (per adjudication). (NCT02556203)
Timeframe: Through study completion, on average 16 months

InterventionParticipants (Count of Participants)
Rivaroxaban (Xarelto, BAY59-7939)83
Antiplatelet68

Number of Participants With Composite Bleeding Endpoint of BARC (Bleeding Academic Research Consortium) 2, 3, or 5 Bleeds

Composite of BARC 2,3 or 5 bleedings (NCT02556203)
Timeframe: Through study completion, on average 16 months

InterventionParticipants (Count of Participants)
Rivaroxaban (Xarelto, BAY59-7939)148
Antiplatelet85

Number of Participants With Death or First Thromboembolic Event (DTE)

Death or first adjudicated thromboembolic event (DTE), defined as composite of all-cause death, any stroke, myocardial infarction (MI), symptomatic valve thrombosis, pulmonary embolism (PE), deep vein thrombosis (DVT), and non-central nervous system (CNS) systemic embolism. (NCT02556203)
Timeframe: Through study completion, on average 14 months

InterventionParticipants (Count of Participants)
Rivaroxaban (Xarelto, BAY59-7939)68
Antiplatelet63

Number of Participants With Death or First Thromboembolic Event (DTE)

Death or first adjudicated thromboembolic event (DTE), defined as composite of all-cause death, any stroke, myocardial infarction (MI), symptomatic valve thrombosis, pulmonary embolism (PE), deep vein thrombosis (DVT), and non-central nervous system (CNS) systemic embolism. (NCT02556203)
Timeframe: Through study completion, on average 16 months

InterventionParticipants (Count of Participants)
Rivaroxaban (Xarelto, BAY59-7939)105
Antiplatelet78

Number of Participants With ISTH (International Society on Thrombosis and Haemostasis) Major Bleeds

ISTH major bleeds (NCT02556203)
Timeframe: Through study completion, on average 16 months

InterventionParticipants (Count of Participants)
Rivaroxaban (Xarelto, BAY59-7939)49
Antiplatelet30

Number of Participants With Net-clinical Benefit

The net-clinical-benefit defined as the adjudicated composite of all-cause death, any stroke, myocardial infarction, symptomatic valve thrombosis, pulmonary embolism, deep vein thrombosis, non-CNS systemic embolism (efficacy); VARC life-threatening, disabling and VARC major bleeds (safety). (NCT02556203)
Timeframe: Through study completion, on average 16 months

InterventionParticipants (Count of Participants)
Rivaroxaban (Xarelto, BAY59-7939)137
Antiplatelet100

Number of Participants With Primary Bleeding Event (PBE)

PBE is defined according to VARC (Valve Academic Research Consortium) definitions as the adjudicated composite of: Life-threatening, disabling or major bleeding. (NCT02556203)
Timeframe: Through study completion, on average 16 months

InterventionParticipants (Count of Participants)
Rivaroxaban (Xarelto, BAY59-7939)46
Antiplatelet31

Number of Participants With TIMI (Thrombolysis In Myocardial Infarction) Major / Minor Bleeds

Composite of TIMI major and minor bleedings (NCT02556203)
Timeframe: Through study completion, on average 16 months

InterventionParticipants (Count of Participants)
Rivaroxaban (Xarelto, BAY59-7939)42
Antiplatelet24

Reviews

21 reviews available for aspirin and Heart Valve Diseases

ArticleYear
Perioperative Cardiovascular Risk Assessment and Management for Noncardiac Surgery: A Review.
    JAMA, 2020, 07-21, Volume: 324, Issue:3

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagul

2020
Antithrombotic therapy management of adult and pediatric cardiac surgery patients.
    Journal of thrombosis and haemostasis : JTH, 2018, Volume: 16, Issue:11

    Topics: Adolescent; Adult; Anticoagulants; Aspirin; Blood Coagulation; Cardiac Surgical Procedures; Cardiolo

2018
Safety and Use of Anticoagulation After Aortic Valve Replacement With Bioprostheses: A Meta-Analysis.
    Circulation. Cardiovascular quality and outcomes, 2016, Volume: 9, Issue:3

    Topics: Anticoagulants; Aortic Valve; Aspirin; Bioprosthesis; Drug Administration Schedule; Heart Valve Dise

2016
Antithrombotic Therapy After Transcatheter Aortic Valve Implantation.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2017, Volume: 17, Issue:4

    Topics: Anticoagulants; Aspirin; Fibrinolytic Agents; Heart Valve Diseases; Humans; Postoperative Complicati

2017
[Antithrombotic therapy in primary and secondary stroke prevention of cardiac patients and in acute stroke].
    Orvosi hetilap, 2009, Feb-01, Volume: 150, Issue:5

    Topics: Acute Disease; Anticoagulants; Aspirin; Atrial Fibrillation; Drug Administration Schedule; Fibrinoly

2009
[Antithrombotic therapy in patients with prosthetic heart valves].
    Kardiologiia, 2010, Volume: 50, Issue:9

    Topics: Anticoagulants; Aspirin; Blood Coagulation Tests; Clopidogrel; Drug Monitoring; Heart Valve Diseases

2010
Antithrombotic therapy in valvular heart disease--native and prosthetic: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
    Chest, 2004, Volume: 126, Issue:3 Suppl

    Topics: Aspirin; Bioprosthesis; Evidence-Based Medicine; Fibrinolytic Agents; Heart Valve Diseases; Heart Va

2004
[Primary and secondary prevention of cardiogenic cerebral embolism].
    No to shinkei = Brain and nerve, 2006, Volume: 58, Issue:10

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Female; Heart Valve Diseases; Humans; Intracrani

2006
Chemistry, measurement, and clinical significance of platelet specific proteins.
    Critical reviews in clinical laboratory sciences, 1982, Volume: 18, Issue:2

    Topics: Aspirin; Beta-Globulins; beta-Thromboglobulin; Blood Coagulation; Blood Coagulation Factors; Blood P

1982
Cardiovascular diseases in the elderly.
    The Medical clinics of North America, 1983, Volume: 67, Issue:2

    Topics: Aged; Aging; Amyloidosis; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Aspirin; Brain Ischemia; Car

1983
Antiplatelet therapy.
    Clinics in haematology, 1981, Volume: 10, Issue:2

    Topics: Aspirin; Blood Platelets; Cerebrovascular Disorders; Clofibrate; Coronary Disease; Dipyridamole; Hea

1981
Cerebrovascular disease.
    Clinics in haematology, 1981, Volume: 10, Issue:2

    Topics: Anticoagulants; Antifibrinolytic Agents; Aspirin; Blood Platelets; Cerebrovascular Disorders; Fibrin

1981
Cardiac manifestations of the antiphospholipid syndrome.
    Coronary artery disease, 1993, Volume: 4, Issue:12

    Topics: Antibodies, Anticardiolipin; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Coronary Disease; H

1993
Treating the non-electrical risks of atrial fibrillation.
    European heart journal, 1997, Volume: 18 Suppl C

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clinical Trials as Topic; Heart Valve Diseases;

1997
Role of transesophageal echocardiography in the management of thromboembolic stroke.
    The American journal of cardiology, 1997, Aug-28, Volume: 80, Issue:4C

    Topics: Anticoagulants; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Aspirin; Cerebrovascular Disorde

1997
Actions and clinical status of platelet-suppressive agents.
    Seminars in hematology, 1978, Volume: 15, Issue:1

    Topics: Aspirin; Blood Platelets; Cerebrovascular Disorders; Coronary Disease; Dipyridamole; Heart Valve Dis

1978
Platelet function inhibitors: their clinical use.
    Advances in internal medicine, 1978, Volume: 23

    Topics: Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Coronary Disease

1978
Platelet suppressive therapy.
    British medical bulletin, 1978, Volume: 34, Issue:2

    Topics: Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clofibrate; Coro

1978
Cardiac thromboembolism: evidence for role of platelets and value of platelet suppressant therapy.
    Advances in experimental medicine and biology, 1978, Volume: 102

    Topics: Aspirin; Blood Platelets; Cell Survival; Clofibrate; Coronary Disease; Heart Diseases; Heart Valve D

1978
[Embolic complications of chronic atrial fibrillation].
    Archives des maladies du coeur et des vaisseaux, 1992, Volume: 85, Issue:3

    Topics: Aspirin; Atrial Fibrillation; Chronic Disease; Heart Valve Diseases; Humans; Primary Prevention; Pro

1992
Effectiveness of anticoagulants.
    Seminars in thrombosis and hemostasis, 1986, Volume: 12, Issue:1

    Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Angina, Unstable; Anticoagulants; Aspirin; Blood

1986

Trials

8 trials available for aspirin and Heart Valve Diseases

ArticleYear
Trial design: Rivaroxaban for the prevention of major cardiovascular events after transcatheter aortic valve replacement: Rationale and design of the GALILEO study.
    American heart journal, 2017, Volume: 184

    Topics: Aortic Valve Stenosis; Aspirin; Cardiovascular Diseases; Cause of Death; Clopidogrel; Drug Therapy,

2017
Trial design: Rivaroxaban for the prevention of major cardiovascular events after transcatheter aortic valve replacement: Rationale and design of the GALILEO study.
    American heart journal, 2017, Volume: 184

    Topics: Aortic Valve Stenosis; Aspirin; Cardiovascular Diseases; Cause of Death; Clopidogrel; Drug Therapy,

2017
Trial design: Rivaroxaban for the prevention of major cardiovascular events after transcatheter aortic valve replacement: Rationale and design of the GALILEO study.
    American heart journal, 2017, Volume: 184

    Topics: Aortic Valve Stenosis; Aspirin; Cardiovascular Diseases; Cause of Death; Clopidogrel; Drug Therapy,

2017
Trial design: Rivaroxaban for the prevention of major cardiovascular events after transcatheter aortic valve replacement: Rationale and design of the GALILEO study.
    American heart journal, 2017, Volume: 184

    Topics: Aortic Valve Stenosis; Aspirin; Cardiovascular Diseases; Cause of Death; Clopidogrel; Drug Therapy,

2017
Effect of site of venous protamine administration, previously alleged risk factors, and preoperative use of aspirin on acute protamine-induced pulmonary vasoconstriction.
    Journal of cardiothoracic and vascular anesthesia, 2003, Volume: 17, Issue:3

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aspirin; Cardiopulmonary Bypass; Constriction, Pathol

2003
Series on pharmacology in practice. 10. Antithrombotic therapy: role of platelet-inhibitor drugs. III. Management of arterial thromboembolic and atherosclerotic disease (third of three parts).
    Mayo Clinic proceedings, 1981, Volume: 56, Issue:4

    Topics: Anticoagulants; Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Coro

1981
[Significance of combined use of anticoagulants and antiplatelet agents in the early stage after prosthetic valve replacement].
    Kyobu geka. The Japanese journal of thoracic surgery, 1995, Volume: 48, Issue:9

    Topics: Adult; Aged; Anticoagulants; Aspirin; Blood Coagulation; Depression, Chemical; Drug Therapy, Combina

1995
Early and long-term (one-year) effects of the association of aspirin and oral anticoagulant on thrombi and morbidity after replacement of the mitral valve with the St. Jude medical prosthesis: a clinical and transesophageal echocardiographic study.
    Journal of the American College of Cardiology, 2000, Mar-01, Volume: 35, Issue:3

    Topics: Administration, Oral; Anticoagulants; Aspirin; Drug Therapy, Combination; Echocardiography, Transeso

2000
[Prevention of arterial embolism by acetylsalicyclic acid and anticoagulants in patients with heart valve prosthesis].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Oct-10, Volume: 96, Issue:28

    Topics: Adult; Aged; Anticoagulants; Aspirin; Clinical Trials as Topic; Drug Therapy, Combination; Embolism;

1976
Modest doses of nitroglycerin do not interfere with beef lung heparin anticoagulation in patients taking nitrates.
    Journal of cardiothoracic and vascular anesthesia, 1992, Volume: 6, Issue:6

    Topics: Adult; Anticoagulants; Aspirin; Drug Administration Schedule; Drug Interactions; Heart Valve Disease

1992
Effectiveness of anticoagulants.
    Seminars in thrombosis and hemostasis, 1986, Volume: 12, Issue:1

    Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Angina, Unstable; Anticoagulants; Aspirin; Blood

1986

Other Studies

48 other studies available for aspirin and Heart Valve Diseases

ArticleYear
Acetylsalicylic Acid Is Associated With a Lower Prevalence of Ascending Aortic Aneurysm and a Decreased Aortic Expression of Cyclooxygenase 2.
    Journal of the American Heart Association, 2022, 05-03, Volume: 11, Issue:9

    Topics: Aorta; Aortic Aneurysm; Aspirin; Cross-Sectional Studies; Cyclooxygenase 2; Heart Valve Diseases; Hu

2022
[Comparison of Various Regimens of Antithrombotic Therapy in Patients With Valvular Heart Disease and Coronary Artery Disease After Surgical and Interventional Interventions].
    Kardiologiia, 2023, Jul-28, Volume: 63, Issue:7

    Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Fibrinolytic Agents; Heart Va

2023
Nonusefulness of Antithrombotic Therapy After Surgical Bioprosthetic Aortic Valve Replacement.
    The American journal of cardiology, 2020, 08-15, Volume: 129

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aortic Valve; Aortic Valve Insufficiency; Aortic Val

2020
Isolated tricuspid valve Libman-Sacks endocarditis in a patient with antiphospholipid antibody syndrome.
    BMJ case reports, 2017, Aug-22, Volume: 2017

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Echocardiography; Endocarditis; Female; H

2017
Stroke in a young man: a late complication of radiation therapy.
    BMJ case reports, 2019, Feb-22, Volume: 12, Issue:2

    Topics: Adult; Anticholesteremic Agents; Aortic Valve; Aspirin; Echocardiography, Transesophageal; Factor Xa

2019
Variation in warfarin thromboprophylaxis after mitral valve repair: does equipoise exist and is a randomized trial warranted?
    The Annals of thoracic surgery, 2013, Volume: 95, Issue:6

    Topics: Aged; Anticoagulants; Aspirin; Cohort Studies; Confidence Intervals; Databases, Factual; Female; Fol

2013
A calcified left ventricular mass.
    Acta cardiologica, 2014, Volume: 69, Issue:3

    Topics: Aged, 80 and over; Aging; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; At

2014
Anticoagulation After Biological Aortic Valve Replacement: Is There An Optimal Regimen?
    The Journal of heart valve disease, 2016, Volume: 25, Issue:2

    Topics: Aged; Anticoagulants; Aortic Valve; Aspirin; Bioprosthesis; Blood Coagulation; Brain Ischemia; Femal

2016
Improved Pig Model to Evaluate Heart Valve Thrombosis.
    The Journal of heart valve disease, 2016, Volume: 25, Issue:5

    Topics: Animals; Aspirin; Blood Coagulation; Blood Platelets; Clopidogrel; Disease Models, Animal; Heart Val

2016
Valvular and structural heart disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
    Chest, 2008, Volume: 133, Issue:6 Suppl

    Topics: Aspirin; Evidence-Based Medicine; Fibrinolytic Agents; Heart Valve Diseases; Humans; Platelet Aggreg

2008
Reduced valve replacement surgery and complication rate in Staphylococcus aureus endocarditis patients receiving acetyl-salicylic acid.
    The Journal of infection, 2009, Volume: 58, Issue:5

    Topics: Aged; Aspirin; Cohort Studies; Embolism; Endocarditis, Bacterial; Female; Heart Failure; Heart Valve

2009
Testing a no-warfarin heart valve.
    Harvard heart letter : from Harvard Medical School, 2006, Volume: 16, Issue:8

    Topics: Anticoagulants; Aspirin; Clopidogrel; Heart Valve Diseases; Heart Valve Prosthesis; Humans; Platelet

2006
Is early antithrombotic therapy necessary in patients with bioprosthetic aortic valves in normal sinus rhythm?
    The Journal of thoracic and cardiovascular surgery, 2010, Volume: 139, Issue:5

    Topics: Aged; Aged, 80 and over; Aortic Valve; Aspirin; Bioprosthesis; Chi-Square Distribution; Drug Adminis

2010
Is early antithrombotic therapy necessary after tissue mitral valve replacement?
    The Journal of heart valve disease, 2010, Volume: 19, Issue:4

    Topics: Aged; Aged, 80 and over; Animals; Anticoagulants; Aspirin; Bioprosthesis; Brain Ischemia; Cattle; Ch

2010
Effect of timing of chronic preoperative aspirin discontinuation on morbidity and mortality in patients having combined coronary artery bypass grafting and valve surgery.
    The American journal of cardiology, 2012, Mar-15, Volume: 109, Issue:6

    Topics: Aged; Aspirin; Coronary Artery Bypass; Coronary Artery Disease; Female; Fibrinolytic Agents; Follow-

2012
Antithrombotic and thrombolytic therapy for valvular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
    Chest, 2012, Volume: 141, Issue:2 Suppl

    Topics: Aspirin; Catheterization; Combined Modality Therapy; Ductus Arteriosus, Patent; Evidence-Based Medic

2012
Cross-sectional study of treatment strategies on atrial fibrillation.
    Arquivos brasileiros de cardiologia, 2012, Volume: 98, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Ambulatory Care; Anti-Arrhythmia Agents; Aspirin; Atrial Fibrilla

2012
Bead-like coronary spasm.
    Internal medicine journal, 2012, Volume: 42, Issue:3

    Topics: Aspirin; Bradycardia; Calcium Channel Blockers; Chest Pain; Coronary Angiography; Coronary Stenosis;

2012
Effect of timing of chronic preoperative aspirin discontinuation on morbidity and mortality in patients having combined coronary artery bypass grafting and valve surgery.
    The American journal of cardiology, 2012, May-01, Volume: 109, Issue:9

    Topics: Aspirin; Coronary Artery Bypass; Coronary Artery Disease; Female; Heart Valve Diseases; Heart Valve

2012
Comparative effects of 3-hydroxy-2-phenylcinchoninic acid (HPC) and aspirin on the acute course of rheumatic fever and the occurrence of rheumatic valvular disease.
    American heart journal, 1953, Volume: 45, Issue:4

    Topics: Aspirin; Heart Valve Diseases; Humans; Quinolines; Rheumatic Fever; Rheumatic Heart Disease

1953
[Effect of adrenocortical hormones, antirheumatic drugs and histaminics on experimental valvulitis and myocarditis caused by O-streptolysin].
    Giornale di clinica medica, 1956, Volume: 37, Issue:1

    Topics: Anti-Allergic Agents; Antirheumatic Agents; Aspirin; Bacterial Proteins; Cortisone; Desoxycorticoste

1956
[REMOTE RESULTS OF HORMONE THERAPY OF RHEUMATIC CHILDREN].
    Sovetskaia meditsina, 1963, Volume: 27

    Topics: Adolescent; Aminopyrine; Arthritis; Arthritis, Rheumatoid; Aspirin; Child; Cortisone; Drug Therapy;

1963
Incidence of anticoagulation in patients with bioprostheses.
    The Journal of heart valve disease, 2004, Volume: 13 Suppl 1

    Topics: Anticoagulants; Aortic Valve; Aspirin; Bioprosthesis; Follow-Up Studies; Heart Valve Diseases; Heart

2004
Clinical and laboratory features of acute rheumatic fever: a 18-year experience.
    Le infezioni in medicina, 2005, Volume: 13, Issue:1

    Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aspirin; Child; Echocardiography; E

2005
An audit of anticoagulation practice among UK cardiothoracic consultant surgeons following valve replacement/repair.
    The Journal of heart valve disease, 2005, Volume: 14, Issue:5

    Topics: Adult; Anticoagulants; Aortic Valve; Aspirin; Bioprosthesis; Consultants; Fibrinolytic Agents; Guide

2005
Clopidogrel-aspirin inhibit the thrombogenicity of St. Jude mechanical aortic prostheses.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:2

    Topics: Aspirin; Clopidogrel; Heart Valve Diseases; Heart Valve Prosthesis Implantation; Humans; Patient Sel

2006
[Early non-obstructive thrombosis of mechanical mitral valve prostheses].
    Archives des maladies du coeur et des vaisseaux, 2005, Volume: 98, Issue:12

    Topics: Adult; Aged; Anticoagulants; Aspirin; Drug Therapy, Combination; Echocardiography, Transesophageal;

2005
Low-molecular-weight heparin in pregnant women with prosthetic heart valves.
    The Journal of heart valve disease, 2006, Volume: 15, Issue:5

    Topics: Adult; Anticoagulants; Antifibrinolytic Agents; Aortic Valve; Aspirin; Biomarkers; Coronary Artery D

2006
Preliminary experience with aspirin for anticoagulation in children with prosthetic cardiac valves.
    The Annals of thoracic surgery, 1982, Volume: 33, Issue:6

    Topics: Adolescent; Anticoagulants; Aortic Valve; Aspirin; Bioprosthesis; Child; Child, Preschool; Dicumarol

1982
Cardiovascular complications of mucocutaneous lymph node syndrome.
    Pediatric clinics of North America, 1984, Volume: 31, Issue:6

    Topics: Aneurysm; Aspirin; Child, Preschool; Coronary Disease; Echocardiography; Female; Heart Diseases; Hea

1984
Performance of aortic and pulmonary homografts in the right ventricular outflow tract in children.
    The Journal of heart valve disease, 1995, Volume: 4, Issue:4

    Topics: Age Factors; Aortic Valve; Aortic Valve Stenosis; Aspirin; Calcinosis; Cardiac Catheterization; Chil

1995
Low dose anticoagulation after St. Jude Medical prosthesis implantation in patients under 18 years of age.
    The Journal of heart valve disease, 1995, Volume: 4, Issue:3

    Topics: Adolescent; Anticoagulants; Aortic Valve; Aspirin; Dipyridamole; Drug Therapy, Combination; Female;

1995
Acute coronary embolism complicating aortic valve endocarditis treated with streptokinase and aspirin. A case report.
    The Journal of heart valve disease, 1994, Volume: 3, Issue:3

    Topics: Aortic Valve; Aspirin; Embolism; Endocarditis, Bacterial; Gastrointestinal Hemorrhage; Heart Valve D

1994
Experience with moderate intensity anticoagulation and aspirin after mechanical valve replacement. A retrospective, non-randomized study.
    The Journal of heart valve disease, 1993, Volume: 2, Issue:3

    Topics: Acenocoumarol; Adult; Aged; Aspirin; Blood Coagulation Tests; Dose-Response Relationship, Drug; Drug

1993
[Myocardial infarction and cerebrovascular accident complicating papillary elastofibroma of the mitral valve].
    Presse medicale (Paris, France : 1983), 1995, Oct-14, Volume: 24, Issue:30

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Ischemia; Fibroma; Heart Neoplasms; He

1995
Risk of stroke in a cohort of 815 patients with calcification of the aortic valve with or without stenosis.
    Stroke, 1996, Volume: 27, Issue:5

    Topics: Age Factors; Aged; Anticoagulants; Aortic Valve; Aortic Valve Stenosis; Aspirin; Calcinosis; Cause o

1996
Experience with low-dose aspirin as thromboprophylaxis for the Tissuemed porcine aortic bioprosthesis: a survey of five years' experience.
    The Journal of heart valve disease, 1998, Volume: 7, Issue:5

    Topics: Aged; Aged, 80 and over; Aortic Valve; Aspirin; Bioprosthesis; Data Collection; Dose-Response Relati

1998
Enoxaparin treatment in women with mechanical heart valves during pregnancy.
    American journal of obstetrics and gynecology, 2001, Volume: 185, Issue:3

    Topics: Adult; Antibodies; Anticoagulants; Aspirin; Enoxaparin; Factor Xa; Female; Heart Valve Diseases; Hea

2001
[Guidelines for antithrombotic therapy in atrial fibrillation: what the Italian Hemostasis and Thrombosis Society thinks].
    Haematologica, 2001, Volume: 86, Issue:9 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Comorbidity; Diabetes

2001
[Acute rheumatic carditis. Follow-up (author's transl)].
    Anales espanoles de pediatria, 1979, Volume: 12, Issue:11

    Topics: Acute Disease; Adrenal Cortex Hormones; Aspirin; Cardiomegaly; Child; Child, Preschool; Endocarditis

1979
[New approaches to selection of an optimal method of treatment of children with rheumatic valvulitis on the basis of a prognostic table obtained with the aid of a computer].
    Pediatriia, 1979, Issue:6

    Topics: Aortic Valve; Aspirin; Child; Computers; Drug Evaluation; Female; Heart Valve Diseases; Humans; Male

1979
[Valvular heart disease].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:11

    Topics: Aortic Valve; Arrhythmias, Cardiac; Aspirin; Digitalis; Echocardiography; Electrocardiography, Ambul

1991
Use of antithrombotic agents in valvular heart disease.
    The Journal of cardiovascular nursing, 1987, Volume: 1, Issue:3

    Topics: Aspirin; Dipyridamole; Heart Valve Diseases; Humans; Patient Education as Topic; Warfarin

1987
Oral anticoagulation is not necessary for patients with bioprosthetic mitral valve replacement in atrial fibrillation.
    Zeitschrift fur Kardiologie, 1986, Volume: 75 Suppl 2

    Topics: Anticoagulants; Aortic Valve; Aspirin; Atrial Fibrillation; Bioprosthesis; Dipyridamole; Drug Therap

1986
Do all patients with mechanical heart valve prostheses need anticoagulant therapy?
    Zeitschrift fur Kardiologie, 1986, Volume: 75 Suppl 2

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Bioprosthesis; Dipyridamole; Drug Therapy, Combination

1986
Anticoagulants: a guide for practitioners.
    Postgraduate medicine, 1973, Volume: 54, Issue:2

    Topics: Angina Pectoris; Anticoagulants; Aspirin; Dicumarol; Disseminated Intravascular Coagulation; Electri

1973
Evaluation of anticoagulant therapy in cloth-covered prosthetic valves.
    Circulation, 1973, Volume: 48, Issue:1 Suppl

    Topics: Anticoagulants; Aortic Valve; Aspirin; Cerebral Hemorrhage; Heart Valve Diseases; Heart Valve Prosth

1973
Some clinical observations on rheumatic fever in childhood. Patterns of the disease as seen in Southern iran.
    Clinical pediatrics, 1971, Volume: 10, Issue:9

    Topics: Adolescent; Aspirin; Blood Sedimentation; Child; Child, Preschool; Chorea; Electrocardiography; Endo

1971