aspirin has been researched along with Hearing Loss, Sensorineural in 23 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Hearing Loss, Sensorineural: Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tinnitus or subjective hearing loss, or both, were reported by 61 of 134 (45%) patients with rheumatoid arthritis (RA) taking regular salicylates and by 73 of 182 (40%) untreated healthy subjects." | 5.06 | Salicylate ototoxicity in patients with rheumatoid arthritis: a controlled study. ( Halla, JT; Hardin, JG, 1988) |
| "The quinine-induced increase in hearing threshold and its recovery can be analysed according to 'the psychophysical power function'." | 2.55 | Concentration-Response Relationship of Hearing Impairment Caused by Quinine and Salicylate: Pharmacological Similarities but Different Molecular Mechanisms. ( Alvan, G; Berninger, E; Gustafsson, LL; Karlsson, KK; Paintaud, G; Wakelkamp, M, 2017) |
| "Susac's syndrome is an extremely rare clinical manifestation characterized by the triad of fluctuating sensorineural hearing loss, sudden visual loss and encephalopathy." | 2.41 | [Susac syndrome as a cause of sensorineural hearing loss]. ( Albaladejo Devis, I; Cubillana Herrero, JD; Jiménez Cervantes-Nicolás, JA; Minguez Merlos, N; Rodríguez González-Herrero, B; Soler Valcárcel, A, 2002) |
| "Ototoxic side effects such as sensorineural hearing loss and tinnitus can be caused by acute salicylate intoxication." | 1.72 | Downbeat Nystagmus and Bilateral Sudden Hearing Loss by Suicidal Aspirin Intoxication. ( Kim, CH; Lee, DH; Noh, H; Shin, JE, 2022) |
| "Aspirin (82%) was the most commonly used ototoxic drug, followed by loop diuretics (77%) and aminoglycosides (57%)." | 1.62 | Pharmacogenetic screening of A1555G and C1494T mitochondrial mutations and the use of ototoxic drugs among Jordanians. ( Al-Trad, B; Bani-Hmoud, M; Rababa'h, AM; Yehya, A, 2021) |
| "Many cases of Susac syndrome are underdiagnosed, mainly at the early stages of the disease, while prompt diagnosis enables a speedy recovery." | 1.43 | Neurological, otolaryngological and ophthalmological implications of Susac syndrome - a case report. ( Czaplicka, E; Grygiel-Górniak, B; Puszczewicz, M, 2016) |
| "We encountered an adolescent with Cogan syndrome complicated by aortitis and anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis." | 1.40 | Childhood Cogan syndrome with aortitis and anti-neutrophil cytoplasmic antibody-associated glomerulonephritis. ( Enya, T; Izu, A; Miyazawa, T; Nishi, H; Okada, M; Sugimoto, K; Takemura, T, 2014) |
| "In some cases, the clinical features of migraine-associated vertigo may mimic the presentation of Menière's disease." | 1.36 | Case reports on two patients with episodic vertigo, fluctuating hearing loss and migraine responding to prophylactic drugs for migraine. Menière's disease or migraine-associated vertigo? ( Bussi, M; Fabiano, B; Limardo, P; Recanati, P; Teggi, R, 2010) |
| "Two patients with sudden sensorineural hearing loss following cervical spine manipulation are presented." | 1.27 | Sudden sensorineural hearing loss following manipulation of the cervical spine. ( Brownson, RJ; Fell, D; Madeira, T; Zollinger, WK, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (30.43) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Nabeyama, W | 1 |
| Ishihara, K | 1 |
| Ban, HS | 1 |
| Wada, H | 1 |
| Nakamura, H | 1 |
| Yehya, A | 1 |
| Al-Trad, B | 1 |
| Bani-Hmoud, M | 1 |
| Rababa'h, AM | 1 |
| Noh, H | 1 |
| Lee, DH | 1 |
| Shin, JE | 1 |
| Kim, CH | 1 |
| Sugimoto, K | 1 |
| Miyazawa, T | 1 |
| Nishi, H | 1 |
| Izu, A | 1 |
| Enya, T | 1 |
| Okada, M | 1 |
| Takemura, T | 1 |
| Kyle, ME | 1 |
| Wang, JC | 1 |
| Shin, JJ | 1 |
| Alvan, G | 1 |
| Berninger, E | 1 |
| Gustafsson, LL | 1 |
| Karlsson, KK | 1 |
| Paintaud, G | 1 |
| Wakelkamp, M | 1 |
| Grygiel-Górniak, B | 1 |
| Puszczewicz, M | 1 |
| Czaplicka, E | 1 |
| Teggi, R | 1 |
| Fabiano, B | 1 |
| Recanati, P | 1 |
| Limardo, P | 1 |
| Bussi, M | 1 |
| Cubillana Herrero, JD | 1 |
| Soler Valcárcel, A | 1 |
| Albaladejo Devis, I | 1 |
| Rodríguez González-Herrero, B | 1 |
| Minguez Merlos, N | 1 |
| Jiménez Cervantes-Nicolás, JA | 1 |
| Orsoni, JG | 1 |
| Zavota, L | 1 |
| Vincenti, V | 1 |
| Pellistri, I | 1 |
| Rama, P | 1 |
| Abdala, C | 1 |
| McFadden, D | 2 |
| Plattsmier, HS | 1 |
| Pasanen, EG | 1 |
| Wildemann, B | 1 |
| Schülin, C | 1 |
| Storch-Hagenlocher, B | 1 |
| Hacke, W | 1 |
| Dithmar, S | 1 |
| Kirchhof, K | 1 |
| Jansen, O | 1 |
| Breitbart, A | 1 |
| Raza, K | 1 |
| Karokis, D | 1 |
| Kitas, GD | 1 |
| Marlowe, FI | 1 |
| Sundel, RP | 1 |
| Cleveland, SS | 1 |
| Beiser, AS | 1 |
| Newburger, JW | 1 |
| McGill, T | 1 |
| Baker, AL | 1 |
| Koren, G | 1 |
| Novak, RE | 1 |
| Harris, JP | 1 |
| Burns, JC | 1 |
| Jordan, CE | 1 |
| Champlin, CA | 1 |
| Halla, JT | 1 |
| Hardin, JG | 1 |
| Brownson, RJ | 1 |
| Zollinger, WK | 1 |
| Madeira, T | 1 |
| Fell, D | 1 |
| Koegel, L | 1 |
| Brown, RD | 1 |
| Henley, CM | 1 |
| Penny, JE | 1 |
| Kupetz, S | 1 |
| Ramsden, RT | 1 |
| Latif, A | 1 |
| O'Malley, S | 1 |
4 reviews available for aspirin and Hearing Loss, Sensorineural
| Article | Year |
|---|---|
Ubiquitous aspirin: a systematic review of its impact on sensorineural hearing loss.
Topics: Aspirin; Hearing Loss, Sensorineural; Humans | 2015 |
Concentration-Response Relationship of Hearing Impairment Caused by Quinine and Salicylate: Pharmacological Similarities but Different Molecular Mechanisms.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Aspirin; Dose-Response Relationship | 2017 |
[Susac syndrome as a cause of sensorineural hearing loss].
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Cerebral Infarction; Cochlea; Combined Modality Therapy; D | 2002 |
Link between functional and morphological changes in the inner ear--functional changes produced by ototoxic agents and their interactions.
Topics: Acetylcysteine; Adult; Aminoglycosides; Aminooxyacetic Acid; Anesthetics; Animals; Anti-Bacterial Ag | 1985 |
1 trial available for aspirin and Hearing Loss, Sensorineural
| Article | Year |
|---|---|
Salicylate ototoxicity in patients with rheumatoid arthritis: a controlled study.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Aspirin; Audiometry; Clinical Trials as Topic | 1988 |
18 other studies available for aspirin and Hearing Loss, Sensorineural
| Article | Year |
|---|---|
Discovery of (2-aminophenyl)methanol as a new molecular chaperone that rescues the localization of P123S mutant pendrin stably expressed in HEK293 cells.
Topics: Amino Acid Substitution; Benzyl Alcohols; Cell Membrane; Goiter, Nodular; Hearing Loss, Sensorineura | 2017 |
Pharmacogenetic screening of A1555G and C1494T mitochondrial mutations and the use of ototoxic drugs among Jordanians.
Topics: Adult; Aminoglycosides; Aspirin; Cross-Sectional Studies; DNA, Mitochondrial; Ear, Inner; Female; Ge | 2021 |
Downbeat Nystagmus and Bilateral Sudden Hearing Loss by Suicidal Aspirin Intoxication.
Topics: Aspirin; Hearing Loss, Bilateral; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Humans; Nystagm | 2022 |
Childhood Cogan syndrome with aortitis and anti-neutrophil cytoplasmic antibody-associated glomerulonephritis.
Topics: Adolescent; Adult; Antibodies, Antineutrophil Cytoplasmic; Antirheumatic Agents; Aortitis; Aspirin; | 2014 |
Neurological, otolaryngological and ophthalmological implications of Susac syndrome - a case report.
Topics: Adult; Aspirin; Hearing Loss, Sensorineural; Humans; Immunoglobulins, Intravenous; Magnetic Resonanc | 2016 |
Case reports on two patients with episodic vertigo, fluctuating hearing loss and migraine responding to prophylactic drugs for migraine. Menière's disease or migraine-associated vertigo?
Topics: Adult; Aspirin; Female; Hearing Loss, Sensorineural; Humans; Meniere Disease; Middle Aged; Migraine | 2010 |
Cogan syndrome in children: early diagnosis and treatment is critical to prognosis.
Topics: Amblyopia; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Autoimmune Diseases; Child; Child, Pres | 2004 |
Effects of aspirin on distortion product otoacoustic emission suppression in human adults: a comparison with neonatal data.
Topics: Acoustic Stimulation; Adolescent; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2005 |
Aspirin-induced hearing loss as a model of sensorineural hearing loss.
Topics: Adult; Aspirin; Hearing Loss; Hearing Loss, Sensorineural; Humans; Male; Models, Biological | 1984 |
Susac's syndrome: improvement with combined antiplatelet and calcium antagonist therapy.
Topics: Adult; Aspirin; Calcium Channel Blockers; Cerebrovascular Disorders; Drug Combinations; Female; Hear | 1996 |
Cogan's syndrome with Takayasu's arteritis.
Topics: Angiography; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents | 1998 |
Ototoxic agents.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Aspirin; Child; Drug-Related Side Effects and Adver | 1978 |
Audiologic profiles of children with Kawasaki disease.
Topics: Aspirin; Audiometry, Pure-Tone; Auditory Threshold; Autoimmunity; Bone Conduction; Child, Preschool; | 1992 |
Case history: asking the right questions.
Topics: Aged; Aspirin; Audiometry, Pure-Tone; Diagnostic Errors; Hearing Loss, Sensorineural; Humans; Male; | 1991 |
Reductions in overshoot during aspirin use.
Topics: Acoustic Stimulation; Adult; Aspirin; Auditory Pathways; Auditory Perception; Hearing Loss, Sensorin | 1990 |
Sudden sensorineural hearing loss following manipulation of the cervical spine.
Topics: Adult; Aspirin; Audiometry; Basilar Artery; Cervical Vertebrae; Chiropractic; Dipyridamole; Female; | 1986 |
Ototoxicity: a contemporary review of aminoglycosides, loop diuretics, acetylsalicylic acid, quinine, erythromycin, and cisplatinum.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Aspirin; Auditory Threshold; Cisplatin; Diuretics; Do | 1985 |
Electrocochleographic changes in acute salicylate overdosage.
Topics: Adult; Aspirin; Audiometry, Evoked Response; Audiometry, Pure-Tone; Cochlea; Female; Hearing Loss, B | 1985 |