aspirin and HIV
aspirin has been researched along with HIV in 8 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted a phase 2, open-label, parallel-design, randomized, controlled trial to assess the safety of high-dose rifampicin, linezolid, and high-dose aspirin in HIV-associated TBM." | 5.69 | A Phase 2A Trial of the Safety and Tolerability of Increased Dose Rifampicin and Adjunctive Linezolid, With or Without Aspirin, for Human Immunodeficiency Virus-Associated Tuberculous Meningitis: The LASER-TBM Trial. ( Aziz, S; Banderker, IA; Black, J; Bremer, M; Candy, S; Crede, T; Daroowala, R; Davis, AG; Denti, P; Goliath, R; Jackson, A; Jason Liang, C; Kadernani, Y; Koekemoer, S; Lai Sai, L; Lai, RPJ; Maartens, G; Maxebengula, M; Meintjes, G; Moosa, MS; Naude, J; Offiah, C; Raubenheimer, P; Sihoyiya, T; Stegmann, S; Stek, C; Szymanski, P; Vallie, Y; Vorster, I; Wahl, G; Wasserman, S; Wilkinson, RJ, 2023) |
| "Using a combination of aspirin, anti-tuberculosis drugs and steroids may help to reduce the number of strokes and deaths in patients with tuberculous meningitis." | 3.88 | Can aspirin help? ( Kalantri, A; Kalantri, S, 2018) |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Davis, AG | 2 |
| Wasserman, S | 2 |
| Stek, C | 2 |
| Maxebengula, M | 2 |
| Jason Liang, C | 2 |
| Stegmann, S | 2 |
| Koekemoer, S | 2 |
| Jackson, A | 2 |
| Kadernani, Y | 2 |
| Bremer, M | 2 |
| Daroowala, R | 2 |
| Aziz, S | 2 |
| Goliath, R | 2 |
| Lai Sai, L | 2 |
| Sihoyiya, T | 2 |
| Denti, P | 2 |
| Lai, RPJ | 2 |
| Crede, T | 2 |
| Naude, J | 2 |
| Szymanski, P | 2 |
| Vallie, Y | 2 |
| Banderker, IA | 2 |
| Moosa, MS | 2 |
| Raubenheimer, P | 2 |
| Candy, S | 2 |
| Offiah, C | 2 |
| Wahl, G | 2 |
| Vorster, I | 2 |
| Maartens, G | 2 |
| Black, J | 2 |
| Meintjes, G | 2 |
| Wilkinson, RJ | 2 |
| Kalantri, A | 1 |
| Kalantri, S | 1 |
| Ayers, J | 1 |
| Mandell, R | 1 |
| Sanghvi, K | 1 |
| Aboujaoude, R | 1 |
| Hsi, DH | 1 |
| De Socio, GV | 1 |
| Ricci, E | 1 |
| Parruti, G | 1 |
| Calza, L | 1 |
| Maggi, P | 1 |
| Celesia, BM | 1 |
| Orofino, G | 1 |
| Madeddu, G | 1 |
| Martinelli, C | 1 |
| Menzaghi, B | 1 |
| Taramasso, L | 1 |
| Penco, G | 1 |
| Carenzi, L | 1 |
| Franzetti, M | 1 |
| Bonfanti, P | 1 |
| Azari, M | 2 |
| Ebeling, A | 2 |
| Baker, R | 1 |
| Burhop, K | 1 |
| Camacho, T | 2 |
| Estep, T | 1 |
| Guzder, S | 2 |
| Marshall, T | 2 |
| Rohn, K | 2 |
| Sarajari, R | 2 |
| Boose, JA | 1 |
| Burhop, KE | 1 |
| Catarello, J | 1 |
| Darling, A | 1 |
| Ebeling, AA | 1 |
| Estep, TN | 1 |
| Pearson, L | 1 |
| Herren, J | 1 |
| Ogle, K | 1 |
| Paine, J | 1 |
| Sun, CS | 2 |
| Zhang, L | 1 |
| Armistead, HS | 1 |
| Farmer, M | 1 |
| Hauck, W | 1 |
| White, E | 1 |
| Long, Z | 1 |
Reviews
1 review available for aspirin and HIV
| Article | Year |
|---|---|
Taking the HIV factory tour.
Topics: Anti-HIV Agents; Aspirin; CD4-Positive T-Lymphocytes; HIV; HIV Infections; Humans; NF-kappa B; Selen | 2001 |
Trials
1 trial available for aspirin and HIV
| Article | Year |
|---|---|
A Phase 2A Trial of the Safety and Tolerability of Increased Dose Rifampicin and Adjunctive Linezolid, With or Without Aspirin, for Human Immunodeficiency Virus-Associated Tuberculous Meningitis: The LASER-TBM Trial.
Topics: Antitubercular Agents; Aspirin; HIV; HIV Infections; Humans; Linezolid; Rifampin; Treatment Outcome; | 2023 |
A Phase 2A Trial of the Safety and Tolerability of Increased Dose Rifampicin and Adjunctive Linezolid, With or Without Aspirin, for Human Immunodeficiency Virus-Associated Tuberculous Meningitis: The LASER-TBM Trial.
Topics: Antitubercular Agents; Aspirin; HIV; HIV Infections; Humans; Linezolid; Rifampin; Treatment Outcome; | 2023 |
A Phase 2A Trial of the Safety and Tolerability of Increased Dose Rifampicin and Adjunctive Linezolid, With or Without Aspirin, for Human Immunodeficiency Virus-Associated Tuberculous Meningitis: The LASER-TBM Trial.
Topics: Antitubercular Agents; Aspirin; HIV; HIV Infections; Humans; Linezolid; Rifampin; Treatment Outcome; | 2023 |
A Phase 2A Trial of the Safety and Tolerability of Increased Dose Rifampicin and Adjunctive Linezolid, With or Without Aspirin, for Human Immunodeficiency Virus-Associated Tuberculous Meningitis: The LASER-TBM Trial.
Topics: Antitubercular Agents; Aspirin; HIV; HIV Infections; Humans; Linezolid; Rifampin; Treatment Outcome; | 2023 |
Other Studies
6 other studies available for aspirin and HIV
| Article | Year |
|---|---|
Can aspirin help?
Topics: Adult; Aspirin; Double-Blind Method; HIV; Humans; Stroke; Tuberculosis, Meningeal | 2018 |
Acute coronary thrombosis and multiple coronary aneurysms in a 22-year-old man with the human immunodeficiency virus.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Aneurysm; Coronary An | 2014 |
Statins and Aspirin use in HIV-infected people: gap between European AIDS Clinical Society guidelines and clinical practice: the results from HIV-HY study.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; | 2016 |
Validation of the heat treatment step used in the production of diaspirin crosslinked hemoglobin (DCLHb) for viral inactivation.
Topics: Animals; Aspirin; Blood Substitutes; Diarrhea Viruses, Bovine Viral; Hemoglobins; Hepatovirus; Herpe | 1998 |
Evaluation and validation of virus removal by ultrafiltration during the production of diaspirin crosslinked haemoglobin (DCLHb).
Topics: Animals; Aspirin; Bacteriophage phi X 174; Cell Line; Diarrhea Viruses, Bovine Viral; Drug Contamina | 2000 |
Validation of virus inactivation by heat treatment in the manufacture of diaspirin crosslinked hemoglobin.
Topics: Aspirin; Blood Substitutes; Cross-Linking Reagents; Cytomegalovirus; Drug Contamination; Evaluation | 1992 |