aspirin has been researched along with Granuloma in 47 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Simvastatin has important immune-modulatory and anti-inflammatory effects independent of lipid lowering effects." | 5.40 | Effect of simvastatin on inflammatory cytokines balance in air pouch granuloma model. ( Al-Gayyar, MM; El-Gayar, AM; Hassan, HM; Ibrahim, TM, 2014) |
| "Curcumin is a yellow-colored plant polyphenol with a long history of medicinal use in ayurvedic, Chinese and Japanese medicine." | 5.35 | Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model. ( Chopra, K; Dhir, A; Kuhad, A; Nandal, S; Sharma, S, 2009) |
| "In this model of chronic inflammation, aspirin, more selective for the inhibition of COX-1 is more effective than the selective COX-2 inhibitors nimesulide and NS-398 at inhibiting granuloma dry weight, vascularity and COX activity." | 3.70 | Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation. ( Gilroy, DW; Tomlinson, A; Willoughby, DA, 1998) |
| "Findings of lung granulomas are not rare but their etiology may be embarrassing in autoptic and especially in bioptic material which is shown in two such cases: a 19-year old drug addict man practising intravenous administration of Alnagon pills and a 54-year old woman working with acrylonitrile fibres." | 3.68 | [Granulomatous processes in the lungs]. ( Dĕdic, K; Horácek, J, 1990) |
| " The anti-inflammatory properties of FPP028 were evaluated through the carrageenan induced paw edema and the cotton pellet induced granuloma and compared with the activity of indomethacin, phenylbutazone, and isoxicam; as a result, the activity of FPP028 was shown to be similar to that of the latter compounds." | 3.67 | Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent. ( Banchelli, G; Bianchini, F; Ignesti, G; Pecori-Vettori, L; Pirisino, R; Rafanelli, D; Raimondi, L, 1986) |
| "A 13-year-old boy affected by bursitis of the R knee and nonossifying fibroma of the distal metaphysis of the R femur, was treated in the weeks prior to surgical intervention with water-soluble aspirin tablets to relieve local pain." | 3.66 | Epithelioid granulomata in a nonossifying fibroma. The possible drug-induced mechanism. ( Comelli, A; Cozzutto, C, 1982) |
| " In a rat paw edema test for anti-inflammatory activity naproxen was 55 times more active than aspirin." | 3.65 | Chemistry and pharmacology of naproxen. ( Dorfman, RI, 1975) |
| "Aspirin 100 mg/kg was used as a positive control." | 1.48 | Methanolic Extract of Leathery Murdah, Terminalia coriacea (Roxb.) Wight and Arn. Leaves Exhibits Anti-Inflammatory Activity in Acute and Chronic Models. ( Al-Sanea, MM; Gamal Mahmoud, M; Khatoon, N; Rahman, HU; Safwan Ali Khan, M, 2018) |
| "Simvastatin has important immune-modulatory and anti-inflammatory effects independent of lipid lowering effects." | 1.40 | Effect of simvastatin on inflammatory cytokines balance in air pouch granuloma model. ( Al-Gayyar, MM; El-Gayar, AM; Hassan, HM; Ibrahim, TM, 2014) |
| "Curcumin is a yellow-colored plant polyphenol with a long history of medicinal use in ayurvedic, Chinese and Japanese medicine." | 1.35 | Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model. ( Chopra, K; Dhir, A; Kuhad, A; Nandal, S; Sharma, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (78.72) | 18.7374 |
| 1990's | 4 (8.51) | 18.2507 |
| 2000's | 4 (8.51) | 29.6817 |
| 2010's | 2 (4.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goudie, AC | 1 |
| Gaster, LM | 1 |
| Lake, AW | 1 |
| Rose, CJ | 1 |
| Freeman, PC | 1 |
| Hughes, BO | 1 |
| Miller, D | 1 |
| Toja, E | 1 |
| Selva, D | 2 |
| Schiatti, P | 2 |
| Safwan Ali Khan, M | 1 |
| Khatoon, N | 1 |
| Al-Sanea, MM | 1 |
| Gamal Mahmoud, M | 1 |
| Rahman, HU | 1 |
| Hassan, HM | 1 |
| Al-Gayyar, MM | 1 |
| El-Gayar, AM | 1 |
| Ibrahim, TM | 1 |
| Nandal, S | 1 |
| Dhir, A | 1 |
| Kuhad, A | 1 |
| Sharma, S | 1 |
| Chopra, K | 1 |
| Wong, F | 1 |
| Ghate, M | 1 |
| Manohar, D | 1 |
| Kulkarni, V | 1 |
| Shobha, R | 1 |
| Kattimani, SY | 1 |
| Weyand, CM | 1 |
| Goronzy, JJ | 1 |
| WINTER, CA | 1 |
| RISLEY, EA | 1 |
| NUSS, GW | 1 |
| CREPAX, P | 1 |
| SILVESTRINI, B | 1 |
| TEOTINO, UM | 1 |
| FRIZ, LP | 1 |
| GANDINI, A | 1 |
| DELLABELLA, D | 1 |
| RADOUCO-THOMAS, S | 1 |
| GRUMBACH, P | 1 |
| NOSAL, G | 1 |
| RADOUCO-THOMAS, C | 1 |
| Cozzutto, C | 1 |
| Comelli, A | 1 |
| Rawlings, CA | 1 |
| Keith, JC | 1 |
| Losonsky, JM | 1 |
| McCall, JM | 1 |
| Lisciani, R | 1 |
| Fattorusso, E | 1 |
| Surano, V | 1 |
| Cozzolino, S | 1 |
| Giannattasio, M | 1 |
| Sorrentino, L | 1 |
| Bluth, R | 1 |
| Duncker, G | 1 |
| Manthey, KF | 1 |
| Lambrecht, JT | 1 |
| Sugishita, E | 1 |
| Amagaya, S | 1 |
| Ogihara, Y | 1 |
| Elzouki, AN | 1 |
| Lindgren, S | 1 |
| Gilroy, DW | 1 |
| Tomlinson, A | 1 |
| Willoughby, DA | 1 |
| Smith, MS | 1 |
| Barker, JD | 1 |
| Vogel, HG | 1 |
| Chang, WC | 1 |
| Murota, SI | 1 |
| Tsurufuji, S | 1 |
| Waisman, J | 1 |
| Bluestone, R | 1 |
| Klinenberg, JR | 1 |
| Kulonen, E | 1 |
| Potila, M | 1 |
| Förström, L | 1 |
| Winkelmann, RK | 1 |
| Kambayashi, Y | 1 |
| Mizushima, Y | 1 |
| Dorfman, RI | 1 |
| Nakamura, H | 1 |
| Shimizu, M | 1 |
| Toft, E | 1 |
| Vyberg, M | 1 |
| Therkelsen, K | 1 |
| Horácek, J | 1 |
| Dĕdic, K | 1 |
| Pirisino, R | 1 |
| Bianchini, F | 1 |
| Banchelli, G | 1 |
| Ignesti, G | 1 |
| Raimondi, L | 1 |
| Pecori-Vettori, L | 1 |
| Rafanelli, D | 1 |
| Tsuji, H | 1 |
| Mörsdorf, K | 1 |
| Anspach, K | 1 |
| Fujimura, H | 2 |
| Tsurumi, K | 2 |
| Go, K | 1 |
| Hiramatsu, Y | 1 |
| Tamura, Y | 1 |
| Arrigoni-Martelli, E | 1 |
| Lerner, LJ | 1 |
| Diena, A | 1 |
| Sardi, A | 1 |
| Maffii, G | 1 |
| Roszkowski, AP | 2 |
| Rooks, W | 1 |
| Tomolonis, A | 1 |
| Miller, L | 1 |
| Pelczarska, AB | 1 |
| Ferreira, SH | 1 |
| DiPasquale, G | 1 |
| Rassaert, C | 1 |
| Richter, R | 1 |
| Welaj, P | 1 |
| Tripp, L | 1 |
| Nozaki, M | 1 |
| Hayashi, M | 1 |
| Nakano, K | 1 |
| Tanaka, K | 1 |
| Iizuka, Y | 1 |
| Mielens, ZE | 1 |
| Rooks, WH | 1 |
| Tomolonis, AJ | 1 |
| Miller, LM | 1 |
| Swingle, KF | 1 |
| Hamilton, RR | 1 |
| Harrington, JK | 1 |
| Kvam, DC | 1 |
| Ito, M | 1 |
| Nakanishi, M | 1 |
| Imamura, H | 1 |
| Maruyama, Y | 1 |
| Barron, DI | 1 |
| Copley, AR | 1 |
| Vallance, DK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of the Benefit of Early Treatment With an Endothelin Inhibitor (Bosentan) in Patients With Sudden Blindness Due to Giant Cell Arteritis: CECIBO[NCT03841734] | Phase 3 | 8 participants (Anticipated) | Interventional | 2019-03-31 | Not yet recruiting | ||
| VCRC Imaging Protocol for Magnetic Resonance and Positron Emission Tomography in Large-vessel Vasculitis (Takayasu's Arteritis):Development as Clinical Trial Outcome Measures[NCT00744952] | 26 participants (Actual) | Observational | 2008-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for aspirin and Granuloma
| Article | Year |
|---|---|
Liver and kidney diseases.
Topics: Acetaminophen; Anemia, Sickle Cell; Animals; Aspirin; Cholestasis; Cysts; Glomerulonephritis, IGA; G | 2002 |
Medium- and large-vessel vasculitis.
Topics: Adolescent; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Dru | 2003 |
Medium- and large-vessel vasculitis.
Topics: Adolescent; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Dru | 2003 |
Medium- and large-vessel vasculitis.
Topics: Adolescent; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Dru | 2003 |
Medium- and large-vessel vasculitis.
Topics: Adolescent; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Dru | 2003 |
Pharmacological properties of naproxen.
Topics: Administration, Oral; Administration, Topical; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory A | 1973 |
Inflammation, prostaglandins and aspirin-like drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Capillary Permeability; Cardiovascular System; Cell Move | 1973 |
43 other studies available for aspirin and Granuloma
| Article | Year |
|---|---|
4-(6-Methoxy-2-naphthyl)butan-2-one and related analogues, a novel structural class of antiinflammatory compounds.
Topics: Animals; Anti-Inflammatory Agents; Female; Gossypium; Granuloma; Naphthalenes; Rats; Structure-Activ | 1978 |
3-Alkyl-2-aryl-3H-naphth[1,2-d]imidazoles, a novel class of nonacidic antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Drug Evaluation, Preclini | 1984 |
Methanolic Extract of Leathery Murdah, Terminalia coriacea (Roxb.) Wight and Arn. Leaves Exhibits Anti-Inflammatory Activity in Acute and Chronic Models.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Disease Models, Animal; Dose-Response Relationship, Drug | 2018 |
Effect of simvastatin on inflammatory cytokines balance in air pouch granuloma model.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; C-Reactive Protein; Cells, Cultured; Cytokines; Disease | 2014 |
Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Curcumin; Cyclooxygenase 2 Inhibitors; Cy | 2009 |
Synthesis of vanillin ethers from 4-(bromomethyl) coumarins as anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzaldehydes; Carrageenan; Coumarins; Ed | 2003 |
ANTI-INFLAMMATORY AND ANTIPYRETIC ACTIVITIES OF INDOMETHACIN, 1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID.
Topics: Acetates; Adrenalectomy; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents | 1963 |
EXPERIMENTAL EVALUATION IN LABORATORY ANIMALS OF ANTI-INFLAMMATORY ANALGESIC DRUGS.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Animals; Animals, Laboratory; Anti-Inflammatory A | 1963 |
THIO DERIVATIVES OF 2,3-DIHYDRO-4H-1,3-BENZOXAZIN-4-ONE. SYNTHESIS AND PHARMACOLOGICAL PROPERTIES.
Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Ascites; Aspirin; Chem | 1963 |
ANTI-INFLAMMATORY EFFECT OF TRIHYDROXYETHYLRUTOSIDE.
Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Aspirin; Flavonoids; G | 1964 |
Epithelioid granulomata in a nonossifying fibroma. The possible drug-induced mechanism.
Topics: Adolescent; Aspirin; Bone Diseases; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Femoral Neo | 1982 |
An aspirin-prednisolone combination to modify postadulticide lung disease in heartworm-infected dogs.
Topics: Animals; Arsenamide; Aspirin; Dirofilariasis; Dog Diseases; Dogs; Drug Therapy, Combination; Granulo | 1984 |
Anti-inflammatory activity of Eryngium maritimum L. rhizome extracts in intact rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Female; Foot; Granuloma; Hydrocortis | 1984 |
[Comparison of the effect of 3-amino-4-mercapto-6-methylpyridazine with various antiphlogistic agents in rat models of inflammation].
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Di | 1982 |
[Necrotizing granulomatous inflammation of the orbit and the paranasal sinuses belonging to the group of rheumatic diseases--clinical and therapeutic aspects].
Topics: Aged; Aspirin; Female; Granuloma; Humans; Orbital Diseases; Paranasal Sinus Diseases | 1982 |
Anti-inflammatory testing methods: comparative evaluation of mice and rats.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Cyproheptadine; Edema; Female; | 1981 |
Granulomatous hepatitis induced by aspirin-kodein analgesics.
Topics: Analgesics; Aspirin; Biopsy; Chemical and Drug Induced Liver Injury; Codeine; Drug Combinations; Gra | 1996 |
Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation.
Topics: Air; Air Sacs; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Croton Oil; Cyclooxygenase | 1998 |
Granulomatous ileocolitis preceded by three years of pauciarticular arthritis.
Topics: Arthritis, Juvenile; Aspirin; Child; Crohn Disease; Granuloma; Humans; Male; Prednisone; Sulfasalazi | 1978 |
Mechanical and chemical properties of various connective tissue organs in rats as influenced by non-steroidal antirheumatic drugs.
Topics: Animals; Aspirin; Biomechanical Phenomena; Bone and Bones; Cartilage; Collagen; Connective Tissue; G | 1977 |
Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma.
Topics: Animals; Arachidonic Acids; Aspirin; Carrageenan; Depression, Chemical; Granuloma; Hydrocortisone; I | 1978 |
Nephropathy and urinary stones in hyperuricemic rats. The effect of aspirin.
Topics: Animals; Aspirin; Disease Models, Animal; Granuloma; Male; Nephritis; Rats; Uric Acid; Urinary Calcu | 1977 |
Effect of the administration of antirheumatic drugs on experimental granuloma in rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cellulose; Cytidine; Granuloma; Hexosamines; Hydroxyprol | 1975 |
Granulomatous panniculitis in erythema nodosum.
Topics: Adult; Aged; Aspirin; Caseins; Erythema Induratum; Erythema Nodosum; Female; Follow-Up Studies; Gran | 1975 |
Anti-inflammatory action of an s-triazine derivative in rats.
Topics: Administration, Topical; Adrenalectomy; Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthri | 1975 |
Chemistry and pharmacology of naproxen.
Topics: Administration, Oral; Adrenalectomy; Animals; Aspirin; Carrageenan; Drug Evaluation, Preclinical; Ed | 1975 |
Effect of anti-inflammatory agents on accelerated granuloma formation in rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Flufenamic Acid; Granuloma; Indomethacin; | 1975 |
Diltiazem-induced granulomatous hepatitis.
Topics: Aged; Aspirin; Atenolol; Chemical and Drug Induced Liver Injury; Diltiazem; Female; Granuloma; Human | 1991 |
[Granulomatous processes in the lungs].
Topics: Acrylonitrile; Adult; Aspirin; Caffeine; Codeine; Drug Combinations; Female; Granuloma; Humans; Lung | 1990 |
Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 1986 |
[Anti-inflammatory principle synthesized by a strain of Serratia sp].
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Bromelains; Carrageenan; Chymotrypsin; Ed | 1969 |
[Efficacy of different antiphlogistic agents with respect to carrageenan-inflammation, compared with other models of inflammation].
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; D | 1971 |
[Pharmacological study of phthalazino-(2,3-b)-phthalazine-5 (14H), 12(7H)-dione (L-5418)].
Topics: Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Barbiturates; Blood Co | 1974 |
Antiinflammatory activity and other pharmacological properties of phthalazino(2,3-b)phthalazine-5,12(7H, 14H)-dione (Diftalone).
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Pressure; Diuresis; Drug Ev | 1974 |
Influence of prostaglandins (Pg) E2 and F2 on the inflammatory process.
Topics: Animals; Arthritis; Aspirin; Carrageenan; Croton Oil; Edema; Foot; Granuloma; Hindlimb; Hydrocortiso | 1973 |
[Pharmacological studies on N-benzoyl-N'-phenyl-2,6-diaminobenzoic acid (F-1). 1. Anti-inflammatory action].
Topics: Adrenal Glands; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis; Ascorbic Acid; Aspirin; B | 1973 |
[Anti-inflammatory effect of bimetopyrol. I. Suppressive effect on acute inflammation].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyproheptadine; Edema; Erythema; Fever; Flufenamic Acid; | 1972 |
Response of "acute phase" globulins in different models of inflammation in rats.
Topics: Acute Disease; Adjuvants, Immunologic; Animals; Arthritis; Aspirin; Disease Models, Animal; Granulom | 1971 |
Anti-inflammatory and analgetic properties of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen).
Topics: Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Fe | 1971 |
3-Benzoyldifluoromethanesulfonanilide, sodium salt (diflumidone sodium, MBR 4164-8): a new anti-inflammatory agent.
Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoates; Car | 1971 |
[Influence of various drugs on the tissue permeability. 5. Comparison of the potency of various anti-inflammatory agents by the dermal tissue permeability test using filter paper implanted subcutaneously in the ventral region of rats].
Topics: Administration, Oral; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Azepines; Bromelains; | 1970 |
Pharmacological investigations of 2-amino-3-ethoxy-carbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Bradykinin; C | 1970 |
Anti-inflammatory and related properties of 4-(p-biphenylyl)-3-hydroxybutyric acid.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Biphenyl Compounds; Blood Pressure; Bronchial | 1968 |