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aspirin and Glomerulonephritis

aspirin has been researched along with Glomerulonephritis in 43 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Glomerulonephritis: Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"Treatment with indomethacin, aspirin, or prednisone has been shown to reduce urinary fibrin/fibrinogen degradation products (F."6.64Modification by drugs of urinary fibrin/fibrinogen degradation products in glomerulonephritis. ( Cash, JD; Clarkson, AR; MacDonald, MK; Robson, JS, 1972)
"Aspirin has been convincingly shown to reduce stroke and death in men with transient ischemic attacks (it may possibly be beneficial to women also), myocardial infarction and death in patients with unstable angina, thromboembolic complications associated with artificial heart valves in patients receiving oral anticoagulants (although gastrointestinal bleeding is prohibitive with this combination), and thrombotic occlusion of silicone rubber arteriovenous cannulae in uremic patients undergoing hemodialysis."6.15Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis. ( Harker, LA, 1986)
"Forty patients with Type I membranoproliferative glomerulonephritis were treated for one year with dipyridamole, 225 mg per day, and aspirin, 975 mg per day, in a prospective, randomized, double-blind, placebo-controlled study."5.05Membranoproliferative glomerulonephritis. A prospective clinical trial of platelet-inhibitor therapy. ( Anderson, CF; Chesebro, JH; Donadio, JV; Fuster, V; Holley, KE; Ilstrup, DM; Mitchell, JC, 1984)
" Twenty four patients aged 48 +/- 17 years (21 with idiopathic glomerulonephritis, one with systemic lupus erythematosus and two with type II diabetes mellitus) were treated with aspirin and dipyridamole or aspirin alone during 23."3.68[Is it justifiable to use antiplatelet drugs as a universal protection in patients with chronic glomerular damage?]. ( Duclos, J, 1993)
"The effects of the antiplatelet agents aspirin (ASA), dipyridamole (DP) and prostacyclin (PGI2) on glomerulonephritis following Habu snake venom have been investigated."3.66Focal mesangial proliferative glomerulonephritis in the rat caused by Habu venom: the effect of antiplatelet agents. ( Cattell, V; Mehotra, A, 1980)
"Nine cases of nephrotic children associated with focal segmental glomerulosclerosis who had failed to respond to prednisone and cyclophosphamide therapy and showed sign of progressive deterioration of renal function, were subjected to the therapeutic combinations of antiplatelet agents + prednisone +/- anticoagulant agents."3.66A new therapeutic approach of nephrotic syndrome associated with focal segmental glomerulosclerosis. ( Futrakul, P, 1980)
" There was no lysozymuria with severe uraemic heart failure, aspirin and paracetamol poisoning, or severe jaundice, nor in two cases of acute glomerulonephritis."3.65Lysozymuria and acute disorders of renal function. ( De Silva, KL; Harrison, JF; Parker, RW, 1973)
"Treatment with indomethacin, aspirin, or prednisone has been shown to reduce urinary fibrin/fibrinogen degradation products (F."2.64Modification by drugs of urinary fibrin/fibrinogen degradation products in glomerulonephritis. ( Cash, JD; Clarkson, AR; MacDonald, MK; Robson, JS, 1972)
"We encountered an adolescent with Cogan syndrome complicated by aortitis and anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis."1.40Childhood Cogan syndrome with aortitis and anti-neutrophil cytoplasmic antibody-associated glomerulonephritis. ( Enya, T; Izu, A; Miyazawa, T; Nishi, H; Okada, M; Sugimoto, K; Takemura, T, 2014)
"Plasmic 6-keto-PGF1a was low."1.32[Endothelium and platelets in pregnant women with chronic glomerulonephritis and therapeutic efficacy of acetylsalicylic acid and dipiridamol]. ( Artem'eva, VB; Gordovskaia, NB; Kozlovskaia, NL; Krylova, MIu; Rogov, VA; Shilov, EM; Sidorova, IS, 2004)
"The purpose of the investigation was to evaluate the long-term administration of 100 mg acetylsalicylic acid in patients with chronic proliferative glomerulonephritis."1.28[Treatment of chronic glomerulonephritis with small doses of acetylsalicylic acid]. ( Jáchymová, M; Knotková, V; Nĕmecek, K; Petrů, I, 1990)
" Optimum drug or combination of drugs and dosage are still controversial."1.26[Inhibition of platelet function in pediatric medicine (author's transl)]. ( Schmidt, B, 1982)
"Two further patients with Goodpasture's syndrome were treated."1.26Immunosuppression and the additive effect of plasma exchange in treatment of rapidly progressive glomerulonephritis. ( Bengtsson, U; Brun, C; Bygren, P; Jonsson, M; Jørgensen, F; Larsen, S; Laurell, AB; Lindholm, T; Norlin, M; Sjöholm, A; Thysell, H, 1982)
"Rats treated with indomethacin showed a marked decrease of proteinuria (tested by the 3% sulfosalicylic aicd method) and a clear ultrastructural picture of hyperplasia and hypertrophy of podocytes."1.26Indomethacin and lysine acetylsalicylate in rats with autologous nephrotoxic serum nephritis. Biochemical and morphological studies. ( Cioffi, A; Conte, F; Di Belgiojoso, GB; Donati, MB; Saruggia, M; Sessa, A, 1978)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199033 (76.74)18.7374
1990's5 (11.63)18.2507
2000's2 (4.65)29.6817
2010's3 (6.98)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamada, S1
Yotsueda, H1
Nagara, T1
Goto, K1
Nakashima, Y1
Hirakata, H1
Fujimi, S1
Tsuruya, K1
Medjeral-Thomas, N1
Ziaj, S1
Condon, M1
Galliford, J1
Levy, J1
Cairns, T1
Griffith, M1
Sugimoto, K1
Miyazawa, T1
Nishi, H1
Izu, A1
Enya, T1
Okada, M1
Takemura, T1
Listernick, R1
Klein-Gitelman, M1
Chadwick, E1
Deal, B1
Tanz, R1
Lane, J1
Rogov, VA2
Shilov, EM1
Kozlovskaia, NL1
Gordovskaia, NB1
Sidorova, IS2
Krylova, MIu1
Artem'eva, VB1
Patrono, C1
Ciabattoni, G1
Patrignani, P1
Filabozzi, P1
Pinca, E1
Satta, MA1
van Dorne, D1
Cinotti, GA1
Pugliese, F1
Pierucci, A1
Simonetti, BM1
Donadio, JV1
Anderson, CF1
Mitchell, JC1
Holley, KE1
Ilstrup, DM1
Fuster, V1
Chesebro, JH1
Carlson, RP1
Gilman, SC1
Hodge, TG1
O'Neill-Davis, L1
Blazek, EM1
Lewis, AJ1
Ogawa, S1
Naruse, T1
Hayslett, JP1
Cattell, V1
Mehotra, A1
Schmidt, B1
Thysell, H1
Bygren, P1
Bengtsson, U1
Lindholm, T1
Norlin, M1
Jonsson, M1
Brun, C1
Larsen, S1
Jørgensen, F1
Sjöholm, A1
Laurell, AB1
Futrakul, P1
Duclos, J1
Tareeva, IE1
Androsova, SO1
Katamadze, KT1
Nikiforova, OV1
Faas, MM1
Schuiling, GA1
Baller, JF1
Valkhof, N1
Bakker, WW1
Kupor, LR1
Lowance, DC1
McPhaul, JJ1
Gladman, DD1
Urowitz, MB1
Keystone, EC1
George, CR2
Clark, WF1
Cameron, JS1
Nanra, RS1
Stuart-Taylor, J1
de Leon, AH1
White, KH1
Zannino, L1
Salvadori, G1
Genova, R1
Barbieri, U1
Cocconcelli, P1
Boselli, F1
Sessa, A1
Cioffi, A1
Conte, F1
Saruggia, M1
Di Belgiojoso, GB1
Donati, MB2
Stewart, JH1
McCarthy, SW1
Storey, BG1
Roberts, BA1
Gallery, E1
Mahony, JF1
Knotková, V2
Petrů, I2
Nĕmecek, K2
Jáchymová, M2
Carmichael, J1
Shankel, SW1
Ehrich, JH1
Wurster, U1
Lütge, M1
Doehring, E1
Oemar, B1
Harker, LA3
West, CD1
Kwong, YL1
Chan, KW1
Chan, MK1
Bang, NU2
Trygstad, W1
Schroeder, JE1
Heidenreich, RO2
Csiscko, BM2
Baker, M1
Trygstad, CW1
Rodda, B1
Slichter, SJ1
Quadracci, LJ1
Striker, GE1
Palester-Chlebowczyk, M1
De Gaetano, G1
Vermylen, J1
Harrison, JF1
Parker, RW1
De Silva, KL1
Burry, HC1
Weiss, HJ1
Clarkson, AR1
MacDonald, MK1
Cash, JD1
Robson, JS1
Haverkorn, MJ1
Valkenburg, HA1
Goslings, WR1

Reviews

6 reviews available for aspirin and Glomerulonephritis

ArticleYear
The role of platelets in glomerulonephritis.
    Advances in nephrology from the Necker Hospital, 1975, Volume: 5

    Topics: Adenosine; Antidepressive Agents; Aspirin; Blood Platelets; Complement System Proteins; Endothelium;

1975
Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia.
    Kidney international, 1978, Volume: 13, Issue:1

    Topics: Adult; Age Factors; Aged; Analgesics; Animals; Aspirin; Australia; Caffeine; Drug Combinations; Fema

1978
[Platelet aggregation inhibitors. Their possible use in pediatric pathology].
    Minerva pediatrica, 1979, Jan-31, Volume: 31, Issue:2

    Topics: Age Factors; Anti-Inflammatory Agents; Aspirin; Child; Clofibrate; Dextrans; Diabetes Mellitus, Type

1979
Effects of nonsteroidal anti-inflammatory drugs on prostaglandins and renal function.
    The American journal of medicine, 1985, Volume: 78, Issue:6 Pt 1

    Topics: Anti-Inflammatory Agents; Aspirin; Epoprostenol; Fenoprofen; Glafenine; Glomerular Filtration Rate;

1985
Antiplatelet drugs in the management of patients with thrombotic disorders.
    Seminars in thrombosis and hemostasis, 1986, Volume: 12, Issue:2

    Topics: Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Blood Coagulation Disorders; Blood Platelets

1986
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical

1986

Trials

7 trials available for aspirin and Glomerulonephritis

ArticleYear
Membranoproliferative glomerulonephritis. A prospective clinical trial of platelet-inhibitor therapy.
    The New England journal of medicine, 1984, May-31, Volume: 310, Issue:22

    Topics: Adolescent; Adult; Aged; Aspirin; Blood Platelets; Cell Survival; Child; Chromium Radioisotopes; Cli

1984
[Acetylsalicylic acid and kurantil in the prevention of pregnancy complications in glomerulonephritis and hypertension].
    Terapevticheskii arkhiv, 1993, Volume: 65, Issue:6

    Topics: Abortion, Spontaneous; Analysis of Variance; Aspirin; Chronic Disease; Dipyridamole; Drug Therapy, C

1993
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical

1986
Psychopathology in systemic lupus erythematosus. I. Psychiatric observations.
    Seminars in arthritis and rheumatism, 1973, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Affective Symptoms; Aspirin; Azathioprine; Brain Diseases; Clinical Trials as Top

1973
A controlled trial of aspirin in childhood glomerular disorders.
    Thrombosis et diathesis haemorrhagica, 1973, Sep-15, Volume: 30, Issue:1

    Topics: Adolescent; Age Factors; Aspirin; Blood Cell Count; Blood Platelets; Child; Child, Preschool; Chroni

1973
Modification by drugs of urinary fibrin/fibrinogen degradation products in glomerulonephritis.
    British medical journal, 1972, Jul-29, Volume: 3, Issue:5821

    Topics: Adolescent; Adult; Aged; Aspirin; Child; Creatinine; Female; Fibrin; Fibrinogen; Glomerulonephritis;

1972
Streptococcal pharyngitis in the general population. I. A controlled study of streptococcal pharyngitis and its complications in the Netherlands.
    The Journal of infectious diseases, 1971, Volume: 124, Issue:4

    Topics: Aspirin; Glomerulonephritis; Humans; Netherlands; Penicillins; Pharyngitis; Rheumatic Fever; Strepto

1971

Other Studies

31 other studies available for aspirin and Glomerulonephritis

ArticleYear
Heterochronic spontaneous rupture of bilateral renal cell carcinomas in a hemodialysis patient.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:6

    Topics: Anemia; Aspirin; Blood Transfusion; Carcinoma, Renal Cell; Glomerulonephritis; Hematuria; Humans; Ki

2013
Retrospective analysis of a novel regimen for the prevention of venous thromboembolism in nephrotic syndrome.
    Clinical journal of the American Society of Nephrology : CJASN, 2014, Volume: 9, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Biomarkers; Female; Fibrinolytic Agents; Gl

2014
Childhood Cogan syndrome with aortitis and anti-neutrophil cytoplasmic antibody-associated glomerulonephritis.
    Pediatric rheumatology online journal, 2014, Volume: 12

    Topics: Adolescent; Adult; Antibodies, Antineutrophil Cytoplasmic; Antirheumatic Agents; Aortitis; Aspirin;

2014
A 7-year-old girl with arthritis and hypertension.
    Pediatric annals, 2004, Volume: 33, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Arthritis, Infectious; Arthritis, J

2004
[Endothelium and platelets in pregnant women with chronic glomerulonephritis and therapeutic efficacy of acetylsalicylic acid and dipiridamol].
    Terapevticheskii arkhiv, 2004, Volume: 76, Issue:12

    Topics: Administration, Oral; Aspirin; Biomarkers; Blood Platelets; Dipyridamole; Embryo Loss; Endothelium;

2004
Evidence for a renal origin of urinary thromboxane B2 in health and disease.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 11

    Topics: Adult; Aspirin; Blood Platelets; Female; Glomerulonephritis; Humans; Kidney; Kinetics; Reference Val

1983
Effects of oral aspirin and oxaprozin on the development of lupus-like disease in MRL/1 mice.
    Journal of immunopharmacology, 1984, Volume: 6, Issue:1-2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Aspirin; Autoim

1984
Effects of various antiplatelet drugs and defibrinating agent on experimental glomerulonephritis in rats.
    The Journal of laboratory and clinical medicine, 1982, Volume: 99, Issue:3

    Topics: Animals; Anticoagulants; Aspirin; Batroxobin; Blood Platelets; Dipyridamole; Glomerulonephritis; Imm

1982
Role of platelets in glomerulonephritis.
    The New England journal of medicine, 1984, May-31, Volume: 310, Issue:22

    Topics: Aspirin; Blood Platelets; Dipyridamole; Glomerulonephritis; Humans

1984
Focal mesangial proliferative glomerulonephritis in the rat caused by Habu venom: the effect of antiplatelet agents.
    British journal of experimental pathology, 1980, Volume: 61, Issue:3

    Topics: Animals; Aspirin; Blood Platelets; Dipyridamole; Epoprostenol; Glomerulonephritis; Glomerulosclerosi

1980
[Inhibition of platelet function in pediatric medicine (author's transl)].
    Klinische Padiatrie, 1982, Volume: 194, Issue:2

    Topics: Age Factors; Aspirin; Child; Dipyridamole; Glomerulonephritis; Graft Rejection; Heart Defects, Conge

1982
Immunosuppression and the additive effect of plasma exchange in treatment of rapidly progressive glomerulonephritis.
    Acta medica Scandinavica, 1982, Volume: 212, Issue:3

    Topics: Adult; Aged; Anti-Glomerular Basement Membrane Disease; Antibodies; Aspirin; Azathioprine; Cyclophos

1982
A new therapeutic approach of nephrotic syndrome associated with focal segmental glomerulosclerosis.
    The International journal of pediatric nephrology, 1980, Volume: 1, Issue:1

    Topics: Adolescent; Anticoagulants; Aspirin; Child; Child, Preschool; Cyclophosphamide; Dipyridamole; Drug T

1980
[Is it justifiable to use antiplatelet drugs as a universal protection in patients with chronic glomerular damage?].
    Revista medica de Chile, 1993, Volume: 121, Issue:3

    Topics: Adolescent; Adult; Aged; Aspirin; Chronic Disease; Clinical Protocols; Dipyridamole; Female; Glomeru

1993
Aspirin treatment of the low-dose-endotoxin-treated pregnant rat: pathophysiologic and immunohistologic aspects.
    The Journal of laboratory and clinical medicine, 1997, Volume: 130, Issue:5

    Topics: Albuminuria; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apyrase; Aspirin; Blood Pressure; Cel

1997
Single and multiple drug therapy in autologous immune complex nephritis in rats.
    The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azathioprine; Basement Membrane; Compleme

1976
Serologically active clinically quiescent systemic lupus erythematosus: a discordance between clinical and serologic features.
    The American journal of medicine, 1979, Volume: 66, Issue:2

    Topics: Adult; Antibodies, Antinuclear; Aspirin; Chloroquine; Complement C3; DNA; DNA Helicases; Female; Glo

1979
[Platelet antiaggregation and anticoagulant drugs in the treatment of proliferative glomerulonephritis in children].
    Minerva pediatrica, 1979, Jan-31, Volume: 31, Issue:2

    Topics: Adolescent; Anticoagulants; Aspirin; Child; Female; Glomerulonephritis; Humans; Male; Platelet Aggre

1979
Indomethacin and lysine acetylsalicylate in rats with autologous nephrotoxic serum nephritis. Biochemical and morphological studies.
    Nephron, 1978, Volume: 22, Issue:4-6

    Topics: Animals; Aspirin; Basement Membrane; Disease Models, Animal; Female; Glomerulonephritis; Immune Sera

1978
Diseases causing end-stage renal failure in New South Wales.
    British medical journal, 1975, Feb-22, Volume: 1, Issue:5955

    Topics: Acetaminophen; Adult; Analgesics; Aspirin; Australia; Caffeine; Codeine; Cystoscopy; Female; Glomeru

1975
[The effect of decreased thromboxane synthesis on proliferative glomerulonephritis].
    Casopis lekaru ceskych, 1991, Oct-18, Volume: 130, Issue:16-17

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Chronic Disease; Creatinine; Female; Glomerular Filtra

1991
[Treatment of chronic glomerulonephritis with small doses of acetylsalicylic acid].
    Casopis lekaru ceskych, 1990, Jun-29, Volume: 129, Issue:26

    Topics: Adult; Aspirin; Chronic Disease; Female; Glomerulonephritis; Humans; Male; Middle Aged

1990
[Enzymuria and kidney diseases in childhood].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:12

    Topics: Acetylglucosaminidase; Adolescent; Aminopeptidases; Anti-Bacterial Agents; Aspirin; CD13 Antigens; C

1986
Childhood membranoproliferative glomerulonephritis: an approach to management.
    Kidney international, 1986, Volume: 29, Issue:5

    Topics: Aspirin; Azathioprine; Child; Cyclophosphamide; Dipyridamole; Drug Administration Schedule; Drug The

1986
Acute post-streptococcal glomerulonephritis followed shortly by acute rheumatic fever.
    Postgraduate medical journal, 1987, Volume: 63, Issue:737

    Topics: Acute Disease; Adolescent; Aspirin; Female; Glomerulonephritis; Humans; Penicillins; Rheumatic Fever

1987
Enhanced platelet function in glomerular renal disease.
    The Journal of laboratory and clinical medicine, 1973, Volume: 81, Issue:5

    Topics: Adenosine Diphosphate; Adolescent; Aspirin; Beta-Globulins; Blood Cell Count; Blood Platelets; Child

1973
A kinetic evaluation of hemostasis in renal disease.
    The New England journal of medicine, 1974, Nov-21, Volume: 291, Issue:21

    Topics: Aspirin; Blood Coagulation; Complement System Proteins; Diabetic Nephropathies; Dipyridamole; Fibrin

1974
Platelet factor-4--properties and clinical significance.
    Advances in experimental medicine and biology, 1972, Volume: 34

    Topics: Adenosine Diphosphate; Aspirin; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Fibri

1972
Lysozymuria and acute disorders of renal function.
    Journal of clinical pathology, 1973, Volume: 26, Issue:4

    Topics: Acetaminophen; Acute Disease; Aspirin; Electroshock; Glomerulonephritis; Heart Failure; Humans; Hypo

1973
Drug-induced nephropathies.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:9

    Topics: Animals; Arthritis, Rheumatoid; Aspirin; Colic; Complement System Proteins; Glomerular Filtration Ra

1973
Inhibition of platelet-induced thrombus formation.
    Schweizerische medizinische Wochenschrift, 1974, Jan-26, Volume: 104, Issue:4

    Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Brain Diseases; Dipyridamole; Epinephrin

1974